FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

ROCHE HOLDING LTD
2. Date of Event Requiring Statement (MM/DD/YYYY)
9/24/2021 

3. Issuer Name and Ticker or Trading Symbol

Jasper Therapeutics, Inc. [JSPR]
(Last)        (First)        (Middle)

GRENZACHERSTRASSE 124, 4070
4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                          ___X___ 10% Owner
_____ Officer (give title below)        _____ Other (specify below)
(Street)

BASEL, V8 CH-4070      

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed(MM/DD/YYYY)
 

6. Individual or Joint/Group Filing(Check Applicable Line)

___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Voting Common Stock 4624606 D (1) 

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(MM/DD/YYYY)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date ExercisableExpiration DateTitleAmount or Number of Shares

Explanation of Responses:
(1) Roche Finance Ltd ("Roche Finance") is the direct beneficial owner of these securities of the Issuer. Roche Finance is a wholly-owned subsidiary of Roche Holding Ltd, a Swiss corporation whose shares are traded on the SIX Swiss Exchange. Roche Holding Ltd is the indirect beneficial owner of these securities of the Issuer.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
ROCHE HOLDING LTD
GRENZACHERSTRASSE 124, 4070
BASEL, V8 CH-4070

X

ROCHE FINANCE LTD
GRENZACHERSTRASSE 122, 4070
BASEL, V8 

X


Signatures
ROCHE FINANCE LTD By: /s/ Beat Kraehenmann Name: Beat Kraehenmann Title: Authorized Signatory10/4/2021
**Signature of Reporting PersonDate

By: /s/ Carole Nuechterlein Name: Carole Neuchterlein Title: Authorized Signatory10/4/2021
**Signature of Reporting PersonDate

ROCHE HOLDING LTD By: /s/ Beat Kraehenmann Name: Beat Kraehenmann Title: Authorized Signatory10/4/2021
**Signature of Reporting PersonDate

By: /s/ Claudia Boeckstiegel Name: Claudia Boeckstiegel Title: Authorized Signatory10/4/2021
**Signature of Reporting PersonDate

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