FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Wong Amy
2. Date of Event Requiring Statement (MM/DD/YYYY)
7/29/2022 

3. Issuer Name and Ticker or Trading Symbol

Apexigen, Inc. [APGN]
(Last)        (First)        (Middle)

C/O APEXIGEN, INC., 75 SHOREWAY ROAD, SUITE C
4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                          _____ 10% Owner
___X___ Officer (give title below)        _____ Other (specify below)
SVP, Finance and Operations /
(Street)

SAN CARLOS, CA 94070      

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed(MM/DD/YYYY)
 

6. Individual or Joint/Group Filing(Check Applicable Line)

_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(MM/DD/YYYY)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date ExercisableExpiration DateTitleAmount or Number of Shares
Employee Stock Option (right to buy)  (1)5/9/2024 Common Stock 22333 $1.27 D  
Employee Stock Option (right to buy)  (1)6/25/2025 Common Stock 8708 $1.47 D  
Employee Stock Option (right to buy)  (1)10/30/2025 Common Stock 230507 $1.66 D  
Employee Stock Option (right to buy)  (1)12/16/2026 Common Stock 15367 $2.25 D  
Employee Stock Option (right to buy)  (1)2/17/2027 Common Stock 13830 $2.25 D  
Employee Stock Option (right to buy)  (1)5/22/2028 Common Stock 71159 $3.62 D  
Employee Stock Option (right to buy)  (2)2/14/2029 Common Stock 28685 $4.59 D  
Employee Stock Option (right to buy)  (3)2/20/2030 Common Stock 25611 $4.59 D  
Employee Stock Option (right to buy)  (4)2/12/2031 Common Stock 15366 $4.59 D  

Explanation of Responses:
(1) The shares subject to the option are fully vested and immediately exercisable.
(2) The shares subject to the option vest in 48 equal monthly installments beginning on March 14, 2019.
(3) The shares subject to the option vest in 48 equal monthly installments beginning on February 1, 2020.
(4) The shares subject to the option vest in 48 equal monthly installments beginning on February 1, 2021.

Remarks:
Exhibit 24 - Power of Attorney

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Wong Amy
C/O APEXIGEN, INC.
75 SHOREWAY ROAD, SUITE C
SAN CARLOS, CA 94070


SVP, Finance and Operations

Signatures
/s/ Francis Sarena, by power of attorney8/8/2022
**Signature of Reporting PersonDate


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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