Exhibit 4.1
AMENDMENT NO. 1 TO RIGHTS AGREEMENT
This Amendment No. 1 to the Rights Agreement (this Amendment) is made and entered into as of December 26, 2024,
by and between Dynavax Technologies Corporation, a Delaware corporation (the Company), and Computershare Trust Company, N.A., a federally chartered trust company, as rights agent (the Rights
Agent), and amends that certain Rights Agreement, dated as of October 28, 2024 (the Agreement), by and between the Company and the Rights Agent. All capitalized terms used but not defined herein shall
have the meanings given to such terms in the Agreement.
WHEREAS, the board of directors of the Company (the
Board) has determined it to be desirable to amend a certain provision of the Agreement on the terms set forth in the Amendment;
WHEREAS, as of the date hereof, no Person (as defined in the Agreement) has become an Acquiring Person (as defined in the Agreement);
WHEREAS, pursuant to Section 27 of the Agreement, prior to such time as any Person becomes an Acquiring Person, the Company
and the Rights Agent may, if directed by the Board, from time to time supplement or amend any provision of the Agreement as the Company may deem necessary or desirable without the approval of any holders of the Company or any other Person other than
the Rights Agent;
WHEREAS, this Amendment is permitted by Section 27 of the Agreement and the Company desires to amend the
Agreement as set forth below; and
WHEREAS, pursuant to the terms of the Agreement, and in accordance with Section 27 thereof,
the Board has directed that the Agreement be amended as set forth in this Amendment, and by its execution and delivery hereof, the Company directs the Rights Agent to execute this Amendment.
NOW, THEREFORE, in consideration of the foregoing and mutual covenants and agreements set forth in the Agreement and this Amendment,
and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Company and the Rights Agent hereby agree as follows:
Section 1. Amendment to Section 28 of the Agreement. Section 28 of the Agreement is hereby
removed and replaced with the following:
The Board shall have the exclusive power and authority to administer this Agreement and to exercise all rights
and powers specifically granted to the Board, or the Company, or as may be necessary or advisable in the administration of this Agreement, including without limitation, the right and power to (i) interpret the provisions of this Agreement, and
(ii) make all determinations deemed necessary or advisable for the administration of this Agreement (including a determination to redeem or not redeem the Rights or to amend the Agreement). Without limiting any of the rights and immunities of
the Rights Agent, all such actions, calculations, interpretations and determinations (including, for purposes of clause (y) below, all omissions with respect to the foregoing) that are done or made by the Board in good faith, shall (x) be
final, conclusive and binding on the Rights Agent and the holders of the Rights, and (y) not subject the Board to any liability to the holders of the Rights. Nothing in this Agreement, express or implied, including any provision requiring or
permitting the Board to take (or refrain from taking) any action or making any determination shall be deemed to limit or eliminate the fiduciary duties of the Board under applicable law. The Rights Agent is entitled always to assume the Board acted
in good faith and shall be fully protected and incur no liability in reliance thereon. Notwithstanding anything herein to the contrary, in no event shall a determination of the Board that may adversely affect the rights of the Rights Agent under
this Agreement be binding upon the Rights Agent without the express written consent of the Rights Agent, in its sole discretion.