TIDMORPH

Open Orphan PLC

27 September 2022

Open Orphan plc

("Open Orphan" or the "Company")

Upcoming Scientific Presentations

Open Orphan plc (AIM: ORPH), (to be renamed hVIVO plc (AIM: HVO) effective 26 October 2022), a rapidly growing specialist contract research organisation (CRO) and world leader in testing infectious and respiratory disease products using human challenge clinical trials, announces that three presentations discussing the data and learnings from recent clinical studies and projects will be presented at two upcoming conferences taking place in Belfast, Northern Ireland.

OPTIONS XI for the Control of Influenza is being held 26 - 29 September 2022 and hVIVO will be at booth 6 during the conference for potential partnering discussions. The 12 (th) International RSV Symposium will take place on 29 September to 2 October 2022 and hVIVO will be at booth 6 during the conference for potential partnering discussions.

Details of the presentations at OPTIONS XI for the Control of Influenza are as follows:

 
 Title:      Immunomodulators and treatment of disease in the influenza 
              human challenge model 
 Abstract:   AOXI0665 
 Date:       Wednesday, 28 September 2022 
 Location:   Hall 1, Poster Board Number: P-532 
 
 
 Title:      Influenza, COVID-19, RSV and HRV: translating efficacy testing 
              of vaccine and drugs from human challenge models to the field 
 Abstract:   AOXI0658 
 Date:       Thursday, 29 September 2022 at 11:12 AM 
 Session:    Oral Abstract Session: Translational: Influenza & COVID-19 
              - Human challenge models 
 

Details of the presentation at the 12(th) International RSV Symposium are as follows:

 
 Title:      RSV vaccines/prophylactics: key learnings from the RSV challenge 
              model and Efficacy of Vaccines 
 Abstract:   ARNI0259 
 Date:       Friday, September 30, 2022 
 
 

The abstracts and posters will be available on hVIVO's website from 4 October 2022 here .

For further information please contact:

 
 Open Orphan plc                                                          +44 (0) 20 7756 1300 
 Yamin Khan, Chief Executive Officer 
 
 Walbrook PR (Financial PR & IR)             +44 (0) 20 7933 8780 or openorphan@walbrookpr.com 
  Stephanie Cuthbert / Phillip                         +44 (0) 7796 794 663 / +44 (0) 7867 984 
  Marriage /                                                                             082 / 
  Louis Ashe-Jepson                                                       +44 (0) 7747 515 393 
 
 
 

Notes to Editors

Open Orphan plc (London and Euronext: ORPH) is changing its name to hVIVO plc (AIM and Euronext: HVO), which is expected to take effect on the AIM market of the London Stock Exchange and the Euronext Growth Exchange market on 26 October 2022.

hVIVO is a rapidly growing contract research company that is a world leader in testing infectious and respiratory disease products using human challenge clinical trials. The Company provides services to Big Pharma, biotech, and government/public health organisations.

The Company has a leading portfolio of human challenge study models for infectious and respiratory diseases and is developing a number of new models, such as malaria and COVID-19, to address the dramatic growth of the global infectious disease market. The Paris and Breda offices have over 25 years of experience providing drug development services such as biometry, data management, statistics CMC, PK and medical writing to third party clients as well as supporting the London-based challenge studies.

hVIVO runs challenge studies in London from its Whitechapel quarantine clinic, its state-of-the-art QMB clinic with its highly specialised on-site virology and immunology laboratory, and its newly opened clinic in Plumbers Row. To recruit volunteers / patients for its studies, the Company leverages its unique clinical trial recruitment capacity via its FluCamp volunteer screening facilities in London and Manchester. The newly opened facilities have expanded the scope of the business to enable the offering of Phase I and Phase II vaccine field trials, PK studies, bridging studies, and patient trials as part of large international multi-centre studies.

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