Optigenex Inc., a World Leader in Advanced DNA Repair, Promotes AC-11(R) Anti-Aging Nutritional Supplement on the iVillage Network Agreement Expands Optigenex's Worldwide Presence NEW YORK, July 26 /PRNewswire-FirstCall/ -- Optigenex Inc., (OTC:OPGX) (BULLETIN BOARD: OPGX) , a leading DNA sciences company, today announced that as part of their marketing initiatives targeting women, Activar AC-11, the company's DNA repair supplement, will be promoted utilizing the iVillage Network. The iVillage Network is a leading women's destination and the number one women's community site online. Optigenex's core product, Activar AC-11 is a nutritional supplement for repairing DNA damage caused by sun, stress, toxins, pollution, and other factors associated with the negative effects of aging. As part of the promotional activities, AC-11 will be marketed online through iVillage advertising and newsletters. "Marketing in iVillage will enable Optigenex to reach a large audience of women who want to be proactive about maintaining good health and well-being," said Anthony A. Bonelli, president and COO of Optigenex. "Our new packaging of AC-11 is now promoted on the iVillage Network, which boasts nearly 15 million unique monthly visitors*." AC-11, a potent extract from a rainforest botanical, is now available in a natural vegetable capsule which can be taken once daily to enhance the body's ability to maintain and repair its DNA. * comScore Media Metrix, June 2005. About Optigenex, Inc. Optigenex Inc. is a world leader in the field of advanced DNA repair. Its core product, Activar(TM) AC-11(R), is a patented product designed to manage the effects of aging and cell damage by supporting the body's natural ability to repair and maintain its DNA. Optigenex is committed to providing life- changing products which support the body's natural defenses against the effects of DNA damage caused by environmental and lifestyle factors. For more information visit the Optigenex website at http://www.ac-11.com/ . Product related inquiries can be directed to Optigenex at 1-866-OPTIGNX or at . These statements have not been evaluated by the Food and Drug Administration (FDA). Optigenex products are not intended to diagnose, treat, cure or prevent any disease. About iVillage Inc. iVillage is "the Internet for women" and consists of several online and offline media-based properties that seek to enrich the lives of women, teenage girls and parents through the offering of unique content, community applications, tools and interactive features. iVillage Inc. (NASDAQ:IVIL) was established in 1995 and is headquartered in New York City. Average monthly page views for iVillage.com and its affiliate Web sites ("The iVillage Network") totaled nearly 443 million for the quarter ended March 31, 2005. In April 2005, according to comScore Media Metrix, The iVillage Network ranked 31st among the top 100 Web and Digital Media properties with approximately 16.5 million unique visitors in the United States and had an average reach of approximately 10% of the total online population and nearly 13% of women 18+ online. Also, according to the same report, The iVillage Network was the number one "women's community site" and the number four "community site" overall on the Web. For more information about iVillage, visit http://www.ivillage.com/ . Contacts: Norman Booth or Hilary Halliwell 973.966.1100 DATASOURCE: Optigenex Inc. CONTACT: Norman Booth, or Hilary Halliwell, , +1-973-966-1100, both for Optigenex Inc. Web site: http://www.ac-11.com/ http://www.optigenex.com/ http://www.ivillage.com/

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