A*STAR’s Genome Institute of Singapore (GIS), NanoString®
Technologies, Inc. (NASDAQ: NSTG), and Next Level Genomics (NLG),
today announced the establishment of a joint laboratory in
Singapore focusing on the application of spatial biology to
identify biomarkers that can predict disease progression and
treatment response. The new lab, called the SpACE-Dx lab
(Spatial Atlas of Clinical Evolution of
Disease), will harness spatial multiomic (gene and protein
expression) technologies to drive research in complex diseases,
with a primary focus on cancer.
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The SpACE-Dx lab will be situated within A*STAR’s GIS facility
and be accessible to the local research community. It aims to
foster collaboration and accelerate advancements in spatial
genomics research.
A*STAR brings to the table its advanced scientific
infrastructure and expertise in genomics research, sequencing
technologies, data analytics, and spatial omics in the areas of
translational cancer biology, infectious disease, and
neurobiology.
NLG, the leading provider of next-generation sequencing services
focused on long-read technologies, will provide the laboratory
expertise in spatial genomics utilising NanoString instruments to
aid researchers in applying cutting-edge spatial technology to
their ongoing research.
As a leader in the growing field of spatial biology,
NanoString’s platforms allow researchers to measure the multi-modal
expression of genes and proteins in the natural context of tissue
structure, including diseased cells such as cancer cells and the
cells within their microenvironment (stromal and immune cells). The
technologies enable scientists to determine how cells change and
interact during the development and progression of disease.
“Next Level Genomics is honoured to be part of this
collaborative effort to add cutting-edge technology from NanoString
to A*STAR’s research efforts. We look forward to a productive
partnership with A*STAR’s GIS, with ongoing support from NanoString
throughout this project,” said Dr. David Klinzing, Chief Technology
Officer of NLG.
NanoString’s Director of Sales for Asia Pacific and Japan, Dr.
Jay Manikandan, noted, “We are delighted to partner with A*STAR’s
GIS and NLG, taking the next step forward to support our mission to
advance science and improve health. As a leader in spatial biology
with the most powerful laboratory tools available on the market
today, including the CosMx SMI, GeoMx DSP, and AtoMx platforms, we
see the joint lab as an important resource for our customers in
Singapore and the greater region. Our tools enable personalised and
scalable solutions that will elevate the experience of researchers
and increase productivity and reliability.”
“We are excited to partner NLG and NanoString and are hopeful
that this collaborative effort will result in significant
discoveries that can be translated into the clinic,” said Dr.
Ramanuj DasGupta, Senior Group Leader at A*STAR’s GIS, who is
leading the effort to establish the SpACE-Dx joint laboratory.
About A*STAR’s Genome Institute of Singapore (GIS)
The Genome Institute of Singapore (GIS) is an institute of the
Agency for Science, Technology and Research (A*STAR). It has a
global vision that seeks to use genomic sciences to achieve
extraordinary improvements in human health and public prosperity.
Established in 2000 as a centre for genomic discovery, the GIS
pursues the integration of technology, genetics and biology towards
academic, economic and societal impact, with a mission to “read,
reveal and write DNA for a better Singapore and world”. Key
research areas at the GIS include Precision Medicine &
Population Genomics, Genome Informatics, Spatial & Single Cell
Systems, Epigenetic & Epitranscriptomic Regulation, Genome
Architecture & Design, and Sequencing Platforms. The genomics
infrastructure at the GIS is also utilised to train new scientific
talent, to function as a bridge for academic and industrial
research, and to explore scientific questions of high impact.
For more information about GIS, please visit
www.a-star.edu.sg/gis
About the Agency for Science, Technology and Research
(A*STAR)
A*STAR is Singapore’s lead public sector R&D agency. Through
open innovation, we collaborate with our partners in both the
public and private sectors to benefit the economy and society. As a
Science and Technology Organisation, A*STAR bridges the gap between
academia and industry. Our research creates economic growth and
jobs for Singapore, and enhances lives by improving societal
outcomes in healthcare, urban living, and sustainability. A*STAR
plays a key role in nurturing scientific talent and leaders for the
wider research community and industry. A*STAR’s R&D activities
span biomedical sciences to physical sciences and engineering, with
research entities primarily located in Biopolis and Fusionopolis.
For ongoing news, visit www.a-star.edu.sg
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About Next Level Genomics (NLG)
NLG is a dedicated PacBio Hi-Fi Long-read sequencing laboratory
in Singapore, providing genome expertise in all areas of research:
genomes, transcriptomes, epigenomes, microbiomes and metagenomes,
with a team of experienced and trained scientists in genomics and
bioinformatics. NLG exists to serve the scientific community – the
entire scientific community – to enable great things from great
minds – as easily as possible. NLG’s mission is to equip
individuals with the tools and expertise needed to harness the
potential of cutting-edge technologies and explore the
transformative questions that pave the way for breakthroughs in
health, agriculture, basic science, or any chosen field. Our goal
is to relieve you from the complexities of technology upkeep,
empowering you to focus on your true strengths: discovering and
innovating.
Next Level Genomics can be found at
www.NextLevelGenomics.com
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About NanoString Technologies, Inc.
NanoString Technologies, is a leader in spatial biology, offers
an ecosystem of innovative discovery and translational research
solutions, empowering our customers to map the universe of biology.
The GeoMx® Digital Spatial Profiler is a flexible and consistent
solution combining the power of whole tissue imaging with gene
expression and protein data for spatial whole transcriptomics and
proteomics. The CosMx™ Spatial Molecular Imager is a single-cell
imaging platform powered by spatial multiomics enabling researchers
to map single cells in their native environments to extract deep
biological insights and novel discoveries from one experiment. The
AtoMx™ Spatial Informatics Platform is a cloud-based informatics
solution with advanced analytics and global collaboration
capabilities, enabling powerful spatial biology insights anytime,
anywhere. At the foundation of our research tools is our nCounter®
Analysis System, which offers a secure way to easily profile the
expression of hundreds of genes, proteins, miRNAs, or copy number
variations, simultaneously with high sensitivity and precision. For
more information, visit www.nanostring.com. The NanoString logo,
NanoString, NanoString Technologies, GeoMx, CosMx and nCounter are
trademarks or registered trademarks of NanoString Technologies,
Inc., in the United States and/or other countries.
NanoString can be found at www.NanoString.com
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version on businesswire.com: https://www.businesswire.com/news/home/20231003819883/en/
Winnie Lim Senior Assistant Director Office of Corporate
Communications / Office of Research Planning & Management
Genome Institute of Singapore, A*STAR Tel: +65 6808 8013 Email:
limcp2@gis.a-star.edu.sg
Doug Farrell Vice President, Investor Relations & Corporate
Communications NanoString Technologies, Inc. Tel: +1 206-602-1768
Email: dfarrell@nanostring.com
Jovin Lee Marketing Manager Next Level Genomics Pte Ltd Tel: +65
9838 1251 Email: jovin@nextlevelgenomics.com
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