Four-decade study of more than 130,000
people measured the risk of your morning bacon or
ballgame hot dog
Key Takeaways
- Eating about two servings per week of processed red meat
raises the risk of dementia by 14% compared to those who eat less
than approximately three servings a month.
- Swapping a serving of processed red meat for a serving of
nuts, beans or tofu every day may lower the risk of dementia by
20%.
- Each additional daily serving of processed red meat was
linked to an extra 1.6 years of global cognitive aging,
including language and executive function.
- The research included more than 130,000 people, followed for
up to 43 years.
PHILADELPHIA, July 31,
2024 /PRNewswire/ -- People who eat at least 1/4
serving of bacon, bologna or other processed red meat a day (about
two servings a week) have a higher risk of dementia than those who
eat less than 1/10 of a serving a day (about three servings a
month), according to a study reported today at the Alzheimer's
Association International
Conference® (AAIC®) 2024, in
Philadelphia and online.
The findings also suggest that people can decrease their risk of
dementia by replacing one serving of processed red meat with one
serving of nuts and legumes, such as beans and peas, every day.
"Prevention of Alzheimer's disease and all other dementia is a
major focus, and the Alzheimer's Association has long encouraged
eating a healthier diet — including foods that are less processed —
because they've been associated with lower the risk of cognitive
decline," said Heather M. Snyder,
Ph.D., Alzheimer's Association vice president of medical and
scientific relations. "This large, long-term study provides a
specific example of one way to eat healthier."
Eating an overall heart-healthy diet may contribute to
decreasing one's risk for cognitive decline and
dementia. However, there isn't a single food or ingredient
that, through rigorous scientific research, has been shown to
prevent, treat or cure Alzheimer's or other dementia. In fact,
it is unlikely that one food or ingredient will have a significant
beneficial effect against a disease as complex as Alzheimer's.
The researchers observed more than 130,000 participants in the
Nurses' Health Study and Health Professionals Follow-Up Study and
tracked them for up to 43 years to assess the association between
red meat and dementia. They identified 11,173 dementia cases. The
researchers assessed the participants' diet every two to four years
based on their answers to food-frequency questionnaires, which
asked them how often they ate a serving of processed red meat,
which includes bacon (two slices), hot dog (one), sausage or
kielbasa (2 ounces or two small links), salami, bologna or other
processed meat sandwiches; and nuts and legumes, including peanut
butter (1 tablespoon), peanuts, walnuts or other nuts (1 ounce),
soy milk (8-ounce glass), string beans, beans or lentils, peas or
lima beans (1/2 cup), or tofu or soy protein.
Reported for the first time at AAIC 2024, the findings showed
that people in the study who ate 1/4 servings or more of processed
red meat daily had a 14% higher risk of dementia than those who ate
less than 1/10 of a serving daily.
The researchers also assessed cognition using the Telephone
Interview for Cognitive Status for 17,458 study participants and
determined that each additional daily serving of processed red meat
was linked to:
- An extra 1.61 years of cognitive aging for global cognition —
overall cognitive function including language, executive function
and processing, and
- An extra 1.69 years of cognitive aging in verbal memory — the
ability to recall and understand words and sentences.
However, replacing one daily serving of processed red meat with
one daily serving of nuts and legumes was linked to a 20% lower
risk of developing dementia and 1.37 fewer years of cognitive
aging in global cognition.
"Study results have been mixed on whether there is a
relationship between cognitive decline and meat consumption in
general, so we took a closer look at how eating different amounts
of both processed and unprocessed meat affects cognitive risk and
function," said Yuhan Li, M.H.S.,
research assistant in the Channing Division of Network Medicine at
Brigham and Women's Hospital and lead author of the study, which
she conducted while a graduate student at the Harvard T.H. Chan
School of Public Health, Boston.
"By studying people over a long period of time, we found that
eating processed red meat could be a significant risk factor for
dementia. Dietary guidelines could include recommendations limiting
it to promote brain health."
"Processed red meat has also been shown to raise the risk of
cancer, heart disease and diabetes. It may affect the brain because
it has high levels of harmful substances such as nitrites
(preservatives) and sodium," Li said.
The researchers also studied unprocessed red meat and did not
uncover a significant association between dementia and eating
unprocessed red meat, such as hamburger, steak or pork chops.
The Alzheimer's Association U.S. Study to Protect Brain Health
Through Lifestyle Intervention to Reduce Risk (U.S. POINTER) is a
two-year clinical trial to evaluate whether lifestyle interventions
that target many risk factors can protect cognitive function in
older adults who are at increased risk for cognitive decline. More
than 2,000 volunteers are enrolled across five study sites. Results
are expected to be reported in 2025.
About the Alzheimer's Association International
Conference® (AAIC®)
The Alzheimer's
Association International Conference (AAIC) is the world's largest
gathering of researchers from around the world focused on
Alzheimer's and other dementias. As a part of the Alzheimer's
Association's research program, AAIC serves as a catalyst for
generating new knowledge about dementia and fostering a vital,
collegial research community.
AAIC 2024 home page: www.alz.org/aaic/
AAIC 2024 newsroom: www.alz.org/aaic/pressroom.asp
AAIC 2024 hashtag: #AAIC24
About the Alzheimer's Association®
The
Alzheimer's Association is a worldwide voluntary health
organization dedicated to Alzheimer's care, support and research.
Our mission is to lead the way to end Alzheimer's and all other
dementia — by accelerating global research, driving risk reduction
and early detection, and maximizing quality care and support. Our
vision is a world without Alzheimer's and all other
dementia®. Visit alz.org or call 800.272.3900.
- Yuhan Li, M.H.S., et al. A
Prospective Study of Long-Term Red Meat Intake, Risk of Dementia,
and Cognitive Function in US Adults. (Funding: National Institutes
of Health R01AG077489, R00DK119412, RF1AG083764, R01NR01999, and
P30DK046200; the Nurses' Health Study was supported by the NIH UM1
CA186107; and the Health Professionals Follow-Up Study was
supported by the NIH U01 CA167552)
*** AAIC 2024 news releases may contain updated data that does
not match what is reported in the following abstract.
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SOURCE Alzheimer's Association