UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

NOTICE OF EFFECTIVENESS

Effective Date: March 19, 2019
Accession Number: 0001493152-19-003319
Submission Type: POS AM
CIK: 0001572552
Company Name: Asterias Biotherapeutics, Inc.
File Number: 333-215154
Asterias Biotherapeutics, Inc. (AMEX:AST)
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