Bruker Daltonics Announces Installations of maXisâ„¢ UHR-TOF Mass Spectrometers in Top-tier Pharmaceutical & Academic Laborat...
12 November 2008 - 11:00PM
Business Wire
Bruker Daltonics announced today that the first production run of
its ultra-high resolution time-of-flight (UHR-TOF) mass
spectrometer maXis� has been delivered to customers. The
revolutionary maXis high-performance system was introduced at this
year�s American Society for Mass Spectrometry Conference in Denver,
and has now been successfully installed in a number of top tier
pharmaceutical research laboratories and in leading academic
institutions. maXis is the first and only instrument available
today that uniquely enables the previously incompatible trends in
modern mass spectrometry of ultra-high mass resolution and very
fast UHPLC chromatographic separations. Exceptional mass accuracy
of better than 1 ppm in MS and MS/MS mode, ultra-high resolution of
40,000 to 60,000, dynamic range over 5 orders of magnitude, high
m/z capabilities, exceptional stability allowing 1.5 mDa
high-resolution extracted ion chromatograms, as well as outstanding
sensitivity are all maintained simultaneously even when coupled to
the fastest available chromatography separation systems, delivering
the most powerful mass spectrometry research system across a broad
range of applications. maXis has already been proven as an
exceptional tool in quantitative proteomics, peptide and intact
protein analysis as well as small molecule identification using the
unique Smartformula� 3D method for on-the-fly unambiguous molecular
formula read-out co-developed with Pfizer, UK. �Since its ASMS
introduction, we have seen unprecedented demand for the maXis
across a very wide range of applications. This demonstrates the
real need for high performance, high resolution small molecule and
protein analysis mass spectrometry tools that provide an
unparalleled level of information,� commented Bruker Daltonics
Executive Vice President Dr. Ian Sanders. �We are also very
gratified that our novel concept for UHR-TOF has in practice
developed into a system that has achieved all its stated
specifications and better after rapid and straight-forward
installations with some leading customers.� After just a two-day
maXis installation at Pfizer in the UK, Dr. Don Richards, Head of
Structure Elucidation and Trace Analysis, was able to gather new
data for the BMSS meeting the following week and commented: "This
is the mass spec that we've all been waiting for! It's the first
time that we've really been able to use 5 decimal places for mass
accuracy and it has already greatly enhanced our productivity." At
an early November mass spectrometry symposium at the Indian
Institute of Science in Bangalore, Professor Phillip C. Wright,
Head of the Chemical & Process Engineering Department at the
University of Sheffield, UK, said: "We have already had impressive
high throughput quantitative data off the maXis, and are very
excited that the demonstrated combination of high speed, very high
resolution and mass accuracy has opened up enormous opportunities
in our investigations of complex proteomes." Professor Andre M.
Deelder, Head of Parasitology & Biomolecular Mass Spectrometry
Units, from the Leiden University Medical Centre in The Netherlands
provided his perspective: "In the last few weeks two maXis
instruments have been installed in our laboratory. We have always
been happy with the excellent data obtained with our Bruker
micrOTOF and micrOTOF-Q mass spectrometers, which are key in many
of our analytical applications. It is now already obvious from the
data generated here in Leiden that the maXis represents yet another
major step forward in highest mass spectrometry performance. We are
confident that this new platform will have a major positive impact
on the quality of our metabolomics and proteomics data." ABOUT
BRUKER DALTONICS For more information about Bruker Daltonics and
Bruker Corporation (NASDAQ: BRKR), please visit www.bdal.com and
www.bruker.com.
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