Bruker Features New High Performance Mass Spectrometry Systems & Applications for the Detailed Analysis of Biotherapeutics at...
23 May 2010 - 9:00PM
Business Wire
At the 58th ASMS conference, Bruker unveils a series of new
products and application solutions targeted to improve the
capabilities of researchers to develop biotherapeutics. As many
biotherapeutics currently under development are protein or peptide
based, Bruker has applied its extensive expertise in protein
analysis to develop solutions for many common tasks in analyzing a
protein or peptide based biotherapeutic including:
- Analysis of Truncations and
Splice Variants
- Identification of Point
Mutations
- Identification of Fusion
Proteins
- Protein Glycoform Analysis
- Glycan Structure
Identification
- PEGylation Analysis
At ASMS, Bruker will feature systems and applications built on
the class leading Flex™ series of MALDI mass spectrometers
for direct N- and C-terminal protein sequence analysis utilizing
Bruker’s innovative top-down Edmass™ protein sequencing
technology. This technique is often able to read dozens of amino
acids from the important terminal residues of a protein, regardless
of any protein modifications, and is superior in many aspects to
traditional Edman sequencing. This application area is further
enhanced by the launch of the new faster, highly efficient
autoflex speed™ at ASMS designed to increase the
productivity and capabilities of development operations.
In addition to the proven micrO-TOF™ and
micrO-TOF-QII™ benchtop LCMS ESI-TOF systems, Bruker has
applied its maXis™ UHR-TOF and amaZon ETD™ ion trap
systems for the analysis of intact proteins and post translational
modifications (PTMs). Several key technical presentations will
highlight the powerful and unique capabilities of these systems to
provide important information for the analysis of potential
biotherapeutics. Utilization of the superior resolution (at least
40,000) and mass accuracy (
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