The Institute for Medical Microbiology of the University Medical Center Goettingen Selects Bruker´s MALDI Biotyper for Bacte...
09 November 2010 - 5:00PM
Business Wire
At the European MALDI Biotyper User Group (‘BUG’)
meeting, Bruker Daltonics announced today that the Institute for
Medical Microbiology of the University Medical Center in
Goettingen, Germany (Universitätsmedizin G�ttingen, or UMG), has
installed the Bruker MALDI Biotyper as their
next-generation, rapid molecular microbial identification system.
The UMG Institute for Medical Microbiology is responsible for
research, teaching and diagnosis of bacteriological, mycological
and parasitological infectious diseases. Moreover the Institute is
also the German National Reference Centre for systemic mycosis and
runs hundreds of yeasts and fungi samples per year. The UMG
globally acknowledged yeasts and fungi specialists have extensive
experience in mycosis infectious diseases, as they characterize and
identify such demanding microorganisms on a daily basis.
The identification of yeasts and fungi on the species level is
one of the most challenging tasks of many microbiology
laboratories. It has been shown in several peer-reviewed
publications that the MALDI Biotyper based molecular
fingerprint of yeasts provides significant differentiation on the
species level. Currently more than 40 different Candida species can
be reliably identified when using the MALDI Biotyper
reference library. This is a major improvement in comparison to the
previous differentiation of just Candida glabrata and non-glabrata
by classical biochemical methods. The MALDI Biotyper library
of yeasts strains provides for a more thorough characterization of
these microorganisms. Moreover, the Institute for Medical
Microbiology participates in Bruker´s efforts in establishing an
international group of experts working on the identification of
multicellular fungi with the MALDI Biotyper approach.
Senior physician Priv. Doz. Dr. med. Michael Weig (UMG)
commented: “After evaluating the currently commercially available
MALDI TOF based microorganisms identification systems, it was clear
to us that the MALDI Biotyper will improve and support our
microbiology work due to its performance in identifying difficult
bacteria, yeasts and fungi samples. Bruker has a long term record
in continuously pushing mass spectrometry based applications for
microbiology beyond current opportunities and borders. Therefore,
we are confident to realize our own research ideas for innovative
fungi applications. Deciding to go with Bruker’s high-end autoflex
TOF/TOF instrument in additional allows us to identify new proteins
as part of complex microorganisms’ cell walls and their biological
functions in respective molecular processes. We will also work on a
better understanding of some resistance mechanisms of yeasts and
fungi, which are not yet fully understood. In addition, we plan to
evaluate how to combine Bruker’s standardized fungi workflow with
current EUCAST recommendations for standardized fungi antibiogram
generation.”
Dr. Guido Mix, Sales Director for Microbiology at Bruker,
commented: “The collaboration with the Institute of Medical
Microbiology is an important milestone validating our efforts to
develop user-friendly and reproducible workflows even for yeasts
and fungi, and we look forward to advancing this field even further
with UMG. More than 30 peer reviewed studies on the MALDI
Biotyper have proven the superior analytical performance
compared to classical identification methods for the well known
standard germs representing roughly 95% of the isolates in most
microbiology labs. Now the MALDI Biotyper can also provide
for reliable identification of these last 5%, including for example
multicellular fungi.”
About the Bruker MALDI Biotyper
Bruker’s dedicated MALDI Biotyper solution enables
molecular identification, taxonomical classification or
dereplication of microorganisms like bacteria, yeasts and fungi.
Classification and identification of microorganisms is achieved
reliably and fast using proteomic fingerprinting with
high-throughput MALDI-TOF mass spectrometry. Applications include
clinical routine microbial identification, environmental and
pharmaceutical analysis, taxonomical research, food and consumer
product processing and quality control, as well as in marine
microbiology. Bruker’s robust MALDI Biotyper method requires
minimal sample preparation efforts and offers low cost per sample.
The MALDI Biotyper is available in a research-use-only
version, as well as in an IVD version according to the EU directive
EC/98/79 in certain EU countries. For more information, please
visit www.bdal.com/maldibiotyper.
About Bruker Corporation
Bruker Corporation is a leading provider of high-performance
scientific instruments and solutions for molecular and materials
research, as well as for industrial and applied analysis. For more
information about Bruker Corporation, please visit
http://www.bruker.com.
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