New MRI CryoProbe™ Delivers Highest Sensitivity in Rat Brain in vivo Imaging
12 May 2014 - 7:00PM
Business Wire
Advanced MRI coil technology will drive new
high resolution applications in small animal neuroimaging
At the joint ISMRM-ESMRMB 2014 meeting, Bruker today announced a
new Phased Array MRI CryoProbe™ for in vivo
neuroimaging that delivers unparalleled access to rat brain
microstructure and biochemistry, previously unresolvable in in vivo
imaging of the rat. The sensitivity increase by up to a factor of
2.4 allows researchers to reduce imaging times by a factor of 5, or
to increase spatial resolution.
4 Channel Phased Array MRI CryoProbe™ for
rat brain (Photo: Business Wire)
The 400 MHz Phased Array MRI CryoProbe is based on
cryogenically-cooled, 4 channel array, RF coil technology that
provides a combination of high sensitivity imaging and parallel
acquisition capabilities for maximum imaging speed and highest
spatial resolution in 9.4 Tesla BioSpec®
systems. This cutting-edge technology provides unrivaled
delineation of key information directly relevant to the early
diagnosis of diseases, based on the in vivo detection of
microscopic anatomical and functional abnormalities in small
animals.
Benefiting from automatic selection, the probe integrates
seamlessly with Bruker’s ParaVision® 6
software, opening up a vast world of imaging protocols and
experimental capabilities to the preclinical imaging researcher.
Thanks to hardware recognition, and automatic tuning and matching
for optimum performance and productivity, the Phased Array
MRI CryoProbe is suited to routine imaging environments. The
corresponding CryoPlatform supplies cold Helium gas via a
closed loop circuit, eliminating any need for handling of cryogens.
The patented temperature shielding technology guarantees safe
operation and optimal performance.
Dr. Wolfgang Weber-Fahr, PI of the Translational Imaging Group
at ZI Mannheim, commented: “We are very excited to work with this
new Phased Array MRI CryoProbe technology and will benefit from the
multi-channel array technology that it uses. This will allow us to
push the boundaries of what is possible with MRI and MRS in rat
imaging in the years to come. The close collaboration with Bruker
will allow us to remain state-of-the-art with our MR hardware and
software, and to explore novel preclinical imaging
technologies.”
Dr. Wulf Jung, President of Bruker BioSpin’s Preclinical Imaging
Division, added: “We are pleased to take this important next step
in MRI CryoProbe preclinical technology, now extended to rat
brain imaging. Having already proven an exceptional success in
neuro and cardio preclinical imaging of mice applications, we are
looking forward to seeing more benefits from this novel technology,
as it brings new insights into neurodegenerative disease in rat
models, beyond what is possible today.”
Bruker is the pioneer and world leader in the development of
cryogenically-cooled probes for high-resolution NMR, with over 1300
units sold worldwide in the last ten years. That expertise and
foresight has been transferred successfully to the MRI
CryoProbe, and in just the last few years, around 60 of these
unique MRI coils have been successfully installed around the
world.
About Bruker Corporation
Bruker Corporation is a leading provider of high performance
scientific instruments and solutions for molecular and materials
research, as well as industrial, diagnostics and applied analysis.
For more information, please visit www.bruker.com.
For more information on Bruker’s preclinical imaging solutions,
please visit www.preclinicalimaging.com.
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Media Contact:Bruker CorporationDr. Thorsten Thiel, +49
(721) 5161 – 6500Director of Marketing
Communicationsthorsten.thiel@bruker.comorInvestor
Contact:Bruker CorporationJoshua Young, +1 978-663-3660, ext.
1479Vice President, Investor Relationsjoshua.young@bruker.com
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