Bruker Introduces Fast BioAFM for Automated Mechanobiology
20 December 2021 - 11:00PM
Business Wire
Novel, high-performance JPK NanoWizard V
enables new dynamic mechanobiology research capabilities with
option for seamless optical microscope integration
Bruker today announced the release of the JPK NanoWizard® V
BioAFM, a novel system that marks a milestone in automation and
ease of use for life science atomic force microscopy research.
NanoWizard V is a very fast, automated BioAFM that can
optionally be fully integrated with advanced optical microscopes.
It enables rapid, quantitative mechanical measurements and the
analysis of dynamics on samples ranging in size from sub-molecular
to cells and tissues. The automated setup, alignment and
re-adjustment of system parameters opens new possibilities for
long-term, self-regulating experiments on mechanobiological
dynamics.
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The JPK NanoWizard V BioAFM (Photo:
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“The system’s promised speed and resolution, ease of use, and
up-to-millimeter-range capabilities make this a game changer for
AFM investigations in nanomedicine and biomedical applications,”
said Dr. David Martinez Martin, Senior Lecturer in Biomedical
Engineering and Co-Chair of the Sensors and Diagnostics Cluster of
the Nanohealth Network at the University of Sydney, Australia. The
focus of Dr. Martinez Martin’s research is on the discovery of new
biomarkers for health and disease, and cell physiology.
“We believe that the NanoWizard V is the most advanced
BioAFM, and it combines three significant innovations in one
system: rapid, quantitative mechanobiology measurements, fast
scanning AFM, and automation that requires minimal user input,”
added Dr. Heiko Haschke, Bruker’s Director of BioAFM. “Over the
last decade, we have gathered a wealth of experience in
quantitative nanomechanics using the PeakForce Tapping® and
Quantitative Imaging (QI) modes. By uniting the best aspects of
both in our new PeakForce-QITM mode, we empower novices and experts
alike to perform high-resolution, quantitative mechanobiology
BioAFM experiments. We expect this new system to significantly
contribute to a more comprehensive understanding of dynamic
cellular processes and correlated molecular mechanisms.”
About the JPK NanoWizard V BioAFM JPK NanoWizard V is the
latest generation of Bruker’s industry-leading BioAFMs. It has been
optimized for high spatio-temporal resolution with a large scan
area, flexible experiment design, and outstanding integration with
advanced optical microscope systems. Its PeakForce-QI mode enables
fast and flexible quantitative nanomechanical measurements,
significantly extending the capabilities of AFM in terms of speed
and resolution. NanoWizard V features novel scanner and
sensor technologies and state-of-the-art control software that
encompasses an intuitive, workflow-based graphical user interface
(GUI) to ensure true, easy-to-use AFM operation. The system
comprises JPK’s signature high-speed, high-performance Vortis 2
control electronics, advanced digital control, and novel software
concepts that enhance its multiparametric imaging capabilities and
data processing routines. With motorized mapping and the
DirectOverlay, DirectTiling, and ExperimentPlanner features,
positions and measurements can be set up to run and realign
automatically, ensuring rapid sample observation and highest force
sensitivity. Combined with the new automated hardware features and
an extensive range of liquid cell and temperature control options,
the JPK NanoWizard V enables users of all levels to
focus entirely on their experiments and is, therefore, the ideal
tool for multi-user environments or imaging facilities.
About JPK BioAFM JPK joined Bruker in July 2018, bringing
in-depth expertise in live-cell imaging, cellular mechanics,
adhesion, and molecular force measurements, optical trapping, and
biological stimulus-response characterization to Bruker’s worldwide
infrastructure and established instrumentation development and
support. JPK BioAFM takes full advantage of the best of both
histories to provide microscopy instrumentation for biomolecular
and cellular imaging, as well as force measurements on single
molecules, cells, and tissues. To learn more about Bruker’s
biological research AFMs, please visit: www.bruker.com/BioAFM.
About Bruker Corporation (NASDAQ: BRKR) Bruker is enabling
scientists to make breakthrough discoveries and develop new
applications that improve the quality of human life. Bruker’s
high-performance scientific instruments and high-value analytical
and diagnostic solutions enable scientists to explore life and
materials at molecular, cellular, and microscopic levels. In close
cooperation with our customers, Bruker is enabling innovation,
improved productivity, and customer success in life science
molecular research, in applied and pharma applications, in
microscopy and nanoanalysis, and in industrial applications, as
well as in cell biology, preclinical imaging, clinical phenomics
and proteomics research and clinical microbiology. For more
information, please visit: www.bruker.com.
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version on businesswire.com: https://www.businesswire.com/news/home/20211220005142/en/
Investor: T: +1 (978) 663-3660 x1479 E:
Investor.Relations@bruker.com
Media: Dr. Gabriela Bagordo Communications Manager BioAFM
Bruker Nano GmbH T: +49 (30) 670990 7500 E:
gabriela.bagordo@bruker.com
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