This Amendment No. 3 (this Amendment) amends and supplements the Tender Offer Statement on
Schedule TO filed with the Securities and Exchange Commission on December 22, 2020 (together with any subsequent amendments and supplements thereto, the Schedule TO), by Tyto Acquisition Corporation, a Delaware corporation
(Purchaser) and a wholly-owned subsidiary of Eli Lilly and Company, an Indiana corporation (Lilly). This Schedule TO relates to the offer by Purchaser to purchase all of the issued and outstanding shares of common stock, par
value, $0.0001 per share (the Shares) of Prevail Therapeutics Inc., a Delaware corporation (Prevail), in exchange for (a) $22.50 per Share, net to the seller in cash, without interest and less any applicable tax withholding,
plus (b) one non-tradable contingent value right (a CVR), which CVR represents the contractual right to receive a contingent payment of up to $4.00 per share, net to the seller in cash,
without interest and less any applicable tax withholding, which amount (or such lesser amount as determined in accordance with the terms and conditions of such contingent value rights agreement to be entered into with a rights agent mutually
agreeable to Lilly and Prevail) will become payable, if at all, if a specified milestone is achieved prior to December 1, 2028 (the Offer Price), on the terms and subject to the conditions set forth in the Offer to Purchase and in
the related Letter of Transmittal, copies of which are attached hereto as Exhibits (a)(1)(A) and (a)(1)(B), respectively.
Except as otherwise set forth
in this Amendment, the information set forth in the Schedule TO remains unchanged and is incorporated herein by reference to the extent relevant to the items in this Amendment. Capitalized terms used but not defined herein have the meanings ascribed
to them in the Schedule TO.
Items 1 through 9 and Item 11.
The disclosure in the Offer to Purchase and Items 1 through 9 and Item 11 of the Schedule TO is hereby amended and supplemented by adding a new paragraph at
the end of Section 15 Conditions of the Offer of the Offer to Purchase to read as follows:
The Antitrust Condition has been satisfied by the expiration of the HSR Act waiting period, effective January 19, 2021 at 11:59
p.m., Eastern time.
The disclosure in the Offer to Purchase and Items 1 through 9 and Item 11 of the Schedule TO is hereby amended and
supplemented by adding the following sentence at the end of the first paragraph in Section 16 Certain Legal Matters; Regulatory Approvals of the Offer to Purchase under the subheading Antitrust
Compliance:
The waiting period applicable to the Offer under the HSR Act expired effective January 19, 2021 at 11:59
p.m., Eastern time. Accordingly, the Antitrust Condition has been satisfied. The Offer continues to be subject to the remaining conditions set forth in Section 15 Conditions of the Offer of the Offer to
Purchase.