VioQuest Pharmaceuticals' VQD-002 Named One of 10 Most Promising Oncology Projects by Windhover
30 July 2008 - 9:30PM
Business Wire
VioQuest Pharmaceuticals (OTCBB: VOQP) announced today that the
company�s novel Akt inhibitor VQD-002 (triciribine phosphate
monohydrate, or TCN-P) has been selected as one of the Top 10 most
promising oncology projects in development available for strategic
partnering by an independent committee assembled by Windhover
Information, a leading provider of business information products
and services to senior executives in the pharmaceutical,
biotechnology, and medical device industries. "Selected companies
have been screened using a strict set of judging criteria for the
Top 10 award and represent what our committee considered the most
attractive cardiovascular opportunities the industry has to offer,"
said Roger Longman, Managing Director of Windhover Information.
"Winners have met rigorous criteria including: unmet medical need,
market potential, diversity of indications, strong science,
multi-level partnering opportunities (biotech and pharma),
potential for new opportunities beyond initial indications, and
corporate stability.� "We are delighted that Windhover has
recognized the potential of VQD-002 to address serious unmet needs
in cancer treatment," said Michael D. Becker, president and chief
executive officer of VioQuest. "With its demonstrated ability to
inhibit Akt and its synergies with many widely used cancer
therapies, VQD-002 represents a potentially important new way to
treat a range of cancers. We look forward to continuing our efforts
to advance this promising compound through clinical development.�
The selection committee was led by Marc Wortman, Ph.D.,
contributing writer to Windhover�s In Vivo and Start Up, and a team
from Campbell Alliance, a leading business development strategy
consulting firm. Drawing on the analytic resources of these
organizations, the group evaluated hundreds of compounds currently
in development for the treatment of cancer prior to selecting
VQD-002 to be among the top ten most attractive. As a selected
company, VioQuest Pharmaceuticals has been invited to present data
on VQD-002 at Windhover�s Therapeutic Area Partnerships conference
on November 3-5, 2008, in Philadelphia, PA. About VQD-002 VQD-002
(triciribine phosphate monohydrate, or TCN-P), a tricyclic
nucleoside that inhibits the activation of Akt, has demonstrated
anti-tumor activity against a wide spectrum of cancers in
preclinical and clinical studies. Amplification, overexpression, or
activation of Akt, also named protein kinase B, have been detected
in a number of human malignancies, including prostate, breast,
ovarian, colorectal, pancreatic, and hematologic cancers.
Activation of Akt is associated with cell survival, malignant
transformation, tumor invasiveness, and chemo-resistance, while
inhibition of Akt activity has been shown to cause cell death.
These attributes make Akt an attractive target for cancer therapy.
About VioQuest Pharmaceuticals VioQuest Pharmaceuticals is a New
Jersey-based biotechnology company dedicated to becoming a
recognized leader in the successful development of novel drug
therapies targeting both the molecular basis of cancer and side
effects of treatment. VioQuest�s oncology portfolio includes:
Xyfid� (1% uracil topical), for the treatment of dry skin
conditions and to manage the burning and itching associated with
various dermatoses; VQD-002 (triciribine phosphate monohydrate), a
targeted inhibitor of Akt activation; and Lenocta� (sodium
stibogluconate), an inhibitor of certain protein tyrosine
phosphatases such as SHP-1, SHP-2, and PTP1B. Further information
about VioQuest can be found at www.vioquestpharm.com. This press
release contains forward-looking statements that involve risks and
uncertainties that could cause VioQuest's actual results and
experiences to differ materially from the anticipated results and
expectations expressed in these forward-looking statements. These
forward-looking statements concern the timing, progress and results
of the clinical development, regulatory processes, potential
clinical trial initiations of VioQuest�s product candidates, as
well as our ability to complete strategic transactions. These
statements are often, but not always, made through the use of words
or phrases such as anticipates, expects, plans, believes, intends,
and similar words or phrases. These statements are based on current
expectations, forecasts and assumptions that are subject to risks
and uncertainties, which could cause actual outcomes and results to
differ materially from these statements. These statements are
subject to various risks and uncertainties and include VioQuest�s
immediate need for additional capital to cover its current
obligations and future operating expenses and fund its clinical
development programs, the possibility that the results of clinical
trials will not support VioQuest's claims, the possibility that
VioQuest's development efforts relating to its product candidates
will not be successful, the inability to obtain regulatory approval
of VioQuest's product candidates, VioQuest's reliance on
third-party researchers to develop its product candidates, its lack
of experience in developing and commercializing pharmaceutical
products, and the possibility that its licenses to develop and
commercialize its product candidates may be terminated. Additional
risks are described in VioQuest's Annual Report on Form 10-KSB for
the year ended December 31, 2007. VioQuest assumes no obligation
and does not intend to update these forward-looking statements,
except as required by law.
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