CBF Cobra Bio-Man.

RNS Number:2264V
Cobra Bio-Manufacturing PLC
10 February 2004

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1.     Name of company

       Cobra Bio-Manufacturing plc

2.     Name of shareholder having a major interest

       Fidelity International Limited and its direct and indirect subsidiaries

3.     Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above
   or in respect of a non-beneficial interest or in the case of an individual holder if it is a holding of that
       person's spouse or children under the age of 18.

       As above

4.     Name of the registered holder(s) and, if more than oneholder, the number of shares held by each of them

       Chase Manhattan Bank London

5.     Number of shares/amount of stock acquired

       N/A

6.     Percentage of issued class

       N/A

7.     Number of shares/amount of stock disposed

       N/A

8.     Percentage of issued class

       N/A

9.     Class of security

       Ordinary Shares of 10p each

10.    Date of transaction

       Not stated

11.    Date company informed

       10th February 2004

12.    Total holding following this notification

       925,900 Ordinary Shares

13.    Total percentage holding of issued class following this notification

       4.75%

14.    Any additional information

15.    Name of contact and telephone number for queries

       Tracey Pughe  - Tel: 01782 714181

16.    Name and signature of authorised company official responsible for making this notification.

       Tracey Pughe

Date of notification: 10th February 2004




            This information is provided by RNS
            The company news service from the London Stock Exchange
END

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