AGM Statement
28 June 2010 - 8:30PM
UK Regulatory
TIDMRGT
AGM STATEMENT
28 June 2010
Commercial Developments
At todays AGM the Chairman of ReGen Therapeutics Plc ('ReGen' or the 'Company')
<AIM:RGT> commented that since the Chairman's Statement of 3 June 2010 there are
additional points which we would like to draw to the attention of shareholders.
There have been encouraging developments in revenue generation. Estimated
revenues for the first half of 2010 are GBP132,000 compared with total revenues in
2009 of GBP56,055. This revenue has come from several of the markets where
Colostrinin(TM) is now on sale and we look to continue this upward trend.
Our Turkish licensee Eczacibasi Ilac Pazarlama A.S ('Eczacibasi')[1] has now
confirmed that it has launched ReGen's nutritional supplement ColostrininTM
under the local tradename 'DynaTM' in the Republic of Turkey.
Since obtaining final product approval on 4 May 2010 Eczacibasi have built a new
marketing and sales team to launch the product and have introduced the product
to key opinion leaders in the market prior to formal launch.
By way of reminder Eczacibasi are supplied with bulk blistered tablets for
which ReGen receive a fee for the active ingredient component. These are
then packaged locally. Revenues to ReGen from Eczacibasi pursuant to the
minimum annual purchase commitments in the distribution agreement are estimated
to be $52,000 in the first year and $104,000 in the second year.
We would also comment that the other aspects of the business are developing as
described in the Chairman's Statement of 3 June. In particular a combination of
fundraising and sales with continuing attention to costs has improved the
Company's financial position since the year end.
Science Update
Zolpidem
South African SPECT Scanning Study - Full Publication
The full paper reporting the results of the SPECT scanning study in South Africa
(first announced in a ReGen press release of 9 November 2009) was published in
the journal Arzneimittel Forschung/ Drug Research. An abstract is available
athttp://www.ncbi.nlm.nih.gov/sites/pubmed by searching under the authors names:
Nyakale NE, Clauss RP, Nel HW, Sathekge MM.
Zolpidem Website
A website drawing together all of the currently available scientific information
on the use of zolpidem in brain trauma has been put together and will be
maintained by Dr Ralf Clauss (http://sites.google.com/site/zolpidemtherapy/).
There is now a link to this from the ReGen website.
Mode of Action Hypothesis Paper
A paper proposing how zolpidem works to overcome the natural brain response to
trauma has been published by Dr Clauss.
http://www.ncbi.nim.nih.gov/pubmed/20347531
Colostrinin(TM)
Austen/Stewart publications - J Nutr and Aging
A publication, by Prof Brian Austen (a former scientific collaborator of ReGen)
and a subsequent letter from Dr M. Stewart (a former collaborator and consultant
to ReGen) further elaborate on the mechanism of how Colostrinin(TM) can protect
human neurones in-vitro from cell death (apoptosis) induced by aggregated beta
amyloid and suggest that this mechanism might be the basis of Colostrinin's(TM)
protective effect in Alzheimer's disease.
Abstracts of both articles are available at:
http://www.ncbi.nlm.nih.gov/sites/pubmed by searching under the authors names.
Douraghi-Zadeh D, Matharu B, Razvi A, Austen B. and Stewart M.G respectively.
For further information, please contact:
Percy Lomax
ReGen Therapeutics Plc
Tel: 020 7153 4920
Roland Cornish/Felicity Geidt
Beaumont Cornish Limited
Tel: 020 7628 3396
David Scott/Nick Bealer
Alexander David Securities Limited
Tel: 020 7448 9820
[1] Eczacibasi http://www.eczacibasi.com is a leading Turkish industrials group
with 40 companies, approximately 9,300 employees and revenues of $3.2bn in
2007. Eczacibasi's Ilac Pazarlama A.S. division is based in Levent-Istanbul,
Turkey.
[HUG#1427734]
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Source: ReGen Therapeutics Plc via Thomson Reuters ONE
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