RNS Number:4969T
Phytopharm PLC
19 December 2003


                    BLOCKLISTING SIX MONTHLY REVIEW


1. NAME OF COMPANY:     PHYTOPHARM PLC



2. NAME OF SCHEME:      THE PHYTOPHARM 1996 UNAPPROVED DISCRETIONARY SHARE 
                        OPTION SCHEME



3. PERIOD OF RETURN:     FROM: 11 JUNE 2003    TO: 10 DECEMBER 2003



4. NUMBER AND CLASS OF SHARES(S)
   (AMOUNT OF STOCK/DEBT SECURITY)
   NOT ISSUED UNDER SCHEME
   AT END OF THE LAST PERIOD: 260,000 ORDINARY SHARES OF 1 PENCE



5. NUMBER OF SHARES ISSUED/ALLOTTED
   UNDER SCHEME DURING PERIOD:        127,024 ORDINARY SHARES OF 1 PENCE



6. BALANCE UNDER SCHEME NOT YET ISSUED/ALLOTTED 
   AT END OF PERIOD:                  132,976 ORDINARY SHARES OF 1 PENCE



7. NUMBER AND CLASS OF SHARE(S) 
   (AMOUNT OF STOCK/DEBT SECURITIES) 
   ORIGINALLY LISTED AND THE DATE OF ADMISSION:     260,000 ORDINARY SHARES OF 1 
                                                    PENCE ON 10TH DECEMBER 2001


PLEASE CONFIRM TOTAL NUMBER OF SHARES IN ISSUE AT THE END OF THE PERIOD
IN ORDER FOR US TO UPDATE OUR RECORDS.

TOTAL SHARES IN ISSUE 38,805,218 ORDINARY SHARES OF 1 PENCE AT 10 DECEMBER 2003

CONTACT FOR QUERIES

NAME:          DR G W CHONG
TELEPHONE:     01480 437697


                      This information is provided by RNS
            The company news service from the London Stock Exchange

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