FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

CELGENE CORP /DE/

2. Date of Event Requiring Statement (MM/DD/YYYY)
3/5/2018 

3. Issuer Name and Ticker or Trading Symbol

Juno Therapeutics, Inc. [JUNO]

(Last)        (First)        (Middle)

86 MORRIS AVENUE, 

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                            ___ X ___ 10% Owner
_____ Officer (give title below)          _____ Other (specify below)

(Street)

SUMMIT, NJ 07901       

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed (MM/DD/YYYY)

 

6. Individual or Joint/Group Filing (Check Applicable Line)

___ Form filed by One Reporting Person
_ X _ Form filed by More than One Reporting Person


Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4) 		2. Amount of Securities Beneficially Owned
(Instr. 4) 		3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5) 		4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock   11109160   I   See Footnote   (1)
Common Stock   88118707   I   See Footnote   (2)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4) 		2. Date Exercisable and Expiration Date
(MM/DD/YYYY) 		3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4) 		4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5) 		6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares

Explanation of Responses:
(1)  These shares are owned directly by Celgene Switzerland LLC, a wholly-owned subsidiary of Celgene Corporation ("Celgene").
(2)  These shares are owned directly by Blue Magpie Corporation, a wholly-owned subsidiary of Celgene.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
CELGENE CORP /DE/
86 MORRIS AVENUE
SUMMIT, NJ 07901
X

Celgene Switzerland LLC
AON HOUSE
30 WOODBOURNE AVENUE
PEMBROKE, D0 HM 08
X

Blue Magpie Corp
86 MORRIS AVENUE
SUMMIT, NJ 07901
X


Signatures
/s/ Peter N. Kellogg, Executive Vice President and Chief Financial Officer, Celgene Corporation 3/6/2018
** Signature of Reporting Person Date

/s/ Kevin Mello, Manager, Celgene Switzerland, LLC 3/6/2018
** Signature of Reporting Person Date

/s/ Peter N. Kellogg, Chief Financial Officer, Blue Magpie Corporation 3/6/2018
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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