TTOO T2 Biosystems Inc

T2 Biosystems, Inc. (NASDAQ: TTOO), a leader in the rapid detection of sepsis-causing pathogens and antibiotic resistance genes, and Prxcision, Inc., innovators behind the real-time AI-powered decision support platform pRxcision®, have announced a co-marketing collaboration intended to deliver a revolutionary solution for patients suspected of bloodstream infections and sepsis, and combat the escalating crisis of antibiotic resistance.

Antibiotic resistance is one of the greatest threats facing modern medicine, with millions of lives at risk. Over 1.27 million deaths are reported annually due to antimicrobial resistance (AMR), which threatens to render essential antibiotics useless. The stakes are high, and time is critical—each hour of delayed targeted treatment can increase the risk of death by up to 8% for sepsis patients. By co-marketing T2 Biosystems’ rapid, direct-from-blood diagnostics and the pRxcision® platform, the companies intend to enable a new, comprehensive approach to infection management. This collaboration is expected to provide hospitals with a powerful solution: rapid identification of pathogens directly from blood in hours, not days, paired with real-time insights and information to guide the best possible treatment decisions—immediately.

A Revolution in Real-Time Care“Imagine being able to detect sepsis-causing pathogens within a few hours and having the information needed to act in real time,” said John Sperzel, CEO of T2 Biosystems. “We believe our collaboration with Prxcision, Inc. brings this vision to life. By combining our direct-from-blood diagnostics with the AI-driven pRxcision® platform, we plan to empower clinicians with the information to stop infections in their tracks—faster than ever before. We believe this collaboration will not only prevent antibiotic misuse but also reduce resistance, save lives, and fundamentally change the way we manage sepsis.”

The Right Treatment at the Right TimeThe pRxcision® platform is designed to leverage data from T2 Biosystems’ diagnostics to provide another level of precision—using advanced pharmacokinetic models, pathogen profiles, and real-time patient data to enable clinicians to prescribe the right drug, dose, and duration as the patient's condition evolves. The platform adapts continuously to changing clinical information, providing ranked, evidence-based treatment regimens that help clinicians optimize care and improve outcomes.

“Our platform delivers real-time insights that were once unimaginable,” said Paul G. Ambrose, CEO of Prxcision, Inc. “pRxcision® brings cutting-edge AI to the patient’s bedside—empowering clinicians to navigate complex decisions with confidence. We are thrilled about this collaboration and believe it can accelerate the adoption of our technology, driving significant improvements in hospitals across the country.”

Unlocking New Growth in a Changing Healthcare LandscapeBeyond improving patient care, this collaboration is intended to drive product adoption and create exciting opportunities for growth in a rapidly evolving market. With speed and accuracy at its core, the combined solution can provide hospitals with a powerful tool to improve outcomes and reduce costs. By offering real-time insights and targeted treatment information, T2 Biosystems and Prxcision, Inc. aim to reduce the burden of AMR, helping healthcare systems across the United States take a proactive stance against one of the top global public health threats.

About T2 BiosystemsT2 Biosystems is commercializing the only FDA-cleared diagnostics capable of detecting sepsis-causing bacterial and fungal pathogens directly from blood in just 3-5 hours—eliminating the need for days-long blood cultures. The T2Bacteria® and T2Candida® Panels identify the most common sepsis-causing pathogens with high sensitivity and specificity, allowing clinicians to act sooner, improve outcomes, and save lives.

About Prxcision, Inc.Prxcision, Inc. leverages two decades of expertise in antibiotic development to create a real-time, AI-powered decision support platform. Integrated with electronic health records, pRxcision® provides clinicians with ranked, evidence-based antibiotic regimens tailored to each patient’s needs. This approach helps stop antibiotic misuse, breaks the cycle of resistance, reduces healthcare costs, and ultimately saves lives.

Forward-Looking StatementsThis press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this press release that do not relate to matters of historical fact should be considered forward-looking statements, including, without limitation, statements regarding the potential for the collaboration between T2 Biosystems and Prxcision, Inc. to deliver a revolutionary solution for patients with suspected of bloodstream infections and sepsis; the likelihood that the collaboration will enable a new, comprehensive approach to infection management; the likelihood that the collaboration will not only prevent antibiotic misuse but also reduce resistance, save lives, and fundamentally change the way we manage sepsis; the likelihood that the collaboration will create a new frontier in antibiotic stewardship and optimize treatment for patients with a bloodstream infection or sepsis; and the likelihood that combining rapid direct-from-blood diagnostics like the T2Bacteria Panel and the T2Candida Panel, with real-time AI-powered decision support tools like the pRxcision® platform can ensure that patients receive the right antibiotics, at the right dose, at the right time, faster than ever before, as well as statements that include the words “expect,” “may,” “should,” “anticipate,” and similar statements of a future or forward-looking nature. These forward-looking statements are based on management’s current expectations. These statements are neither promises nor guarantees, but involve known and unknown risks, uncertainties and other important factors that may cause actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements, including, but not limited to, (i) any inability to (a) realize anticipated benefits from commitments, contracts or products; (b) successfully execute strategic priorities; (c) bring products to market; (d) expand product usage or adoption; (e) obtain customer testimonials; (f) accurately predict growth assumptions; (g) realize anticipated revenues; (h) incur expected levels of operating expenses; or (i) increase the number of high-risk patients at customer facilities; (ii) failure of early data to predict eventual outcomes; (iii) failure to make or obtain anticipated FDA filings or clearances within expected time frames or at all; or (iv) the factors discussed under Item 1A. “Risk Factors” in T2 Biosystems‘ Annual Report on Form 10-K for the year ended December 31, 2023, filed with the U.S. Securities and Exchange Commission, or SEC, on April 1, 2024, and other filings T2 Biosystems makes with the SEC from time to time, including our Quarterly Reports on Form 10-Q and Current Reports on Form 8-K. These and other important factors could cause actual results to differ materially from those indicated by the forward-looking statements made in this press release. Any such forward-looking statements represent management’s estimates as of the date of this press release. While T2 Biosystems and Prxcision may elect to update such forward-looking statements at some point in the future, unless required by law, it disclaims any obligation to do so, even if subsequent events cause their respective views to change. Thus, no one should assume that any silence by T2 Biosystems or Prxcision over time means that actual events are bearing out as expressed or implied in such forward-looking statements. These forward-looking statements should not be relied upon as representing the views of T2 Biosystems or Prxcision as of any date subsequent to the date of this press release.

Investor Contacts:Philip Trip Taylor, Gilmartin Groupir@T2Biosystems.com415-937-5406

Prxcision, Inc.info@pRxcision.com518-631-8191