Aastrom Biosciences, Inc. (Nasdaq:ASTM), the leading developer of patient-specific, expanded multicellular therapies for the treatment of severe, chronic cardiovascular diseases, today announced results from a preclinical study demonstrating the ability of ixmyelocel-T to protect the ischemic heart from damage in a murine model of heart failure. Results were presented at the 18th Annual International Society for Cellular Therapy Meeting in a poster presentation entitled "Ixmyelocel-T protects the heart from damage in a murine model of heart failure."

In a blinded, vehicle-controlled study, a murine model of non-acute left anterior descending (LAD) coronary artery occlusion was used to evaluate ixmyelocel-T as a potential treatment for dilated cardiomyopathy (DCM).  Hearts were analyzed four weeks following injection and those in the treated group experienced a significant decrease in infarct length compared to the vehicle control group. The results were consistent between two lots of ixmyelocel-T (Lot 1: 2.72+/- 0.77 vs. 6.14+/- 0.43, P

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