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Agreement “Strengthens Intellectual Property Estate Around TRC102 and Provides Opportunity for Development of Additional Predictive Biomarkers”
TRACON Pharmaceuticals (Nasdaq:TCON), a clinical stage biopharmaceutical company focused on the development and commercialization of novel targeted therapeutics for cancer, age-related macular degeneration and fibrotic diseases, announced today that it entered into an amended license agreement and a new sponsored research collaboration with Case Western Reserve University (CWRU).
The amended agreement strengthens the intellectual property estate around TRC102 by including additional issued patents and patent applications covering combinations of TRC102 with certain approved chemotherapeutic agents as well as patents covering the use of biomarkers that may be used to predict which patients are most likely to respond to TRC102 treatment. In addition, TRACON and CWRU have entered into a sponsored research agreement whereby CWRU will further assess biomarkers that may predict the activity of regimens combining TRC102 with chemotherapeutics, including Alimta® (pemetrexed).
“We are happy to expand our productive partnership with Case Western Reserve University and look forward to their continued support of our TRC102 clinical development program,” noted Charles Theuer, M.D., Ph.D., President and CEO of TRACON. “We believe that this partnership, along with our collaboration with the National Cancer Institute, will help maximize TRC102’s potential to reverse resistance to chemotherapy, a characteristic that could improve outcomes of patients with lung cancer, brain cancer as well as other malignancies.”
TRACON develops targeted therapies for cancer, age-related macular degeneration and fibrotic diseases. TRACON’s current pipeline includes two clinical stage product candidates: TRC105, an anti-endoglin antibody that is being developed for the treatment of renal cell carcinoma, soft tissue sarcoma, hepatocellular carcinoma, glioblastoma and choriocarcinoma, and TRC102, a small molecule that is being developed for the treatment of lung cancer and glioblastoma. Both TRC105 and TRC102 are being developed for treatment in combination with currently available therapies.
