Immupharma PLC Holding(s) in Company (1806Z)
25 May 2016 - 4:01PM
UK Regulatory
TIDMIMM
RNS Number : 1806Z
Immupharma PLC
25 May 2016
RNS : FOR IMMEDIATE RELEASE 25 May 2016
NOTIFICATION OF MAJOR INTEREST BY ALTO INVEST
ImmuPharma PLC (LSE:IMM) ("ImmuPharma" or the "Company"), the
specialist drug discovery and development company, announces that
on 24 May 2016 it received notification by Alto Invest and its
subsidiaries ("Alto") confirming its holding in ImmuPharma of
4,870,367 million Ordinary Shares in the capital of the Company,
representing 3.99% of the Company's total voting rights, crossing
above the 3% threshold.
Alto Invest is an independent asset management firm regulated by
the French financial markets authority and is a specialised
investor in European small and mid-cap companies.
Commenting, Tim McCarthy, Chairman of ImmuPharma, said: "Alto
initially participated in ImmuPharma's successful GBP8.4 million
fundraising in February this year following detailed due-diligence
of our Lupuzor(TM) Phase III pivotal trial. We are delighted that
it has increased its holding and we can now disclose that Alto is a
significant shareholder in ImmuPharma."
-Ends-
For further information please
contact:
+ 44 (0) 20
ImmuPharma plc (www.immupharma.org) 7152 4080
Tim McCarthy, Chairman
Lisa Baderoon, Head of Investor
Relations + 44 (0) 7721
Twitter: @immupharma 413 496
Panmure, Gordon & Co., NOMAD & +44 (0) 20 7886
Broker 2500
Fred Walsh, Duncan Monteith, Corporate
Finance
Charles Leigh-Pemberton, Corporate
Broking
Notes to Editors
ImmuPharma PLC
ImmuPharma is a pharmaceutical development company listed since
2006 on AIM of the London Stock Exchange (LSE:IMM), focusing on
developing novel medicines with high sales potential in specialist
markets with serious unmet need. ImmuPharma is led by a
commercially focused Board and management team with extensive
experience.
ImmuPharma announced on 1 March 2016 the successful completion
of a GBP8.4 million fund raise, comprising a Placing and
Subscription together with confirmation of EIS and VCT qualifying
status. Monies raised will principally be used to complete the
pivotal Phase III trial of Lupuzor(TM). Following the issue of the
New Ordinary Shares ImmuPharma has 121,781,219 ordinary shares of
10 pence each (the "Ordinary Shares") in issue.
Lupuzor(TM)
Lupuzor(TM) (also referred to as forigerimod, rigerimod,
IPP-201101 or P140 is ImmuPharma's lead compound and a potential
treatment for lupus (or Systemic Lupus Erythematosus), a chronic,
potentially life-threatening auto-immune disease. Lupuzor(TM) has a
novel mechanism of action aimed at modulating the body's immune
system so that it does not attack healthy cells, and avoids causing
adverse side effects. It has the potential to halt the progression
of the disease in a substantial proportion of patients.
Lupuzor(TM) has been granted Fast Track status by the US FDA and
approval to start Phase III under Special Protocol Assessment
(SPA). This SPA was subsequently amended due to its strong safety
and efficacy profile to allow for a reduced number of patients in
the pivotal Phase III trial thereby reducing the projected cost and
time of development considerably.
The pivotal Phase III clinical study is entitled "A 52-Week,
Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study
to Evaluate the Efficacy and Safety of a 200-mcg Dose of IPP-201101
Plus Standard of Care in Patients With Systemic Lupus
Erythematosus". It is a pivotal study designed to demonstrate the
safety and efficacy of IPP-201101 and as a last step prior to the
filing of the drug for approval with the US Food & Drug
Administration ("FDA") and the European Medicines Agency ("EMA").
For more information please visit:
www.ClinicalTrials.gov/lupuzor
Commercial Opportunity
There are an estimated five million people globally suffering
from Lupus, with approximately 1.5 million patients in the US,
Europe and Japan (Source: Lupus Foundation of America). Current
'standard of care' treatments, including steroids and
immunosuppressants, can potentially have either serious side
effects for patients or limited effectiveness, with over 60% of
patients not adequately treated. GSK's Benlysta is the first Lupus
drug approved in over 50 years and paves the path to market for
Lupuzor(TM). Based on conservative estimates, and taking into
account that Benlysta is priced currently at approximately $35,000
per patient per year, Lupuzor(TM) would be entering a market with
the potential for multi-billion dollar sales. For more information
on Lupuzor(TM) please visit: www.lupuzor.com
This information is provided by RNS
The company news service from the London Stock Exchange
END
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