WPD Pharmaceuticals Licensor Announces New Independent In Vitro Testing Confirms Antiviral Activity of WP1122 in Coronavirus
23 July 2020 - 9:30PM
WPD Pharmaceuticals Inc. (CSE: WBIO)(FSE: 8SV1) (the
“
Company” or “
WPD”), a clinical
stage pharmaceutical company, is pleased to announce that Moleculin
Biotech Inc. (“
Moleculin”), the company that
sublicenses the compound WP1122 to WPD for 29 countries mainly in
Europe, announced that a second round of independent laboratory
testing has confirmed the antiviral activity of WP1122 against
coronavirus.
Moleculin’s July 21, 2020 press release states,
“Moleculin contracted with IIT Research Institute (an affiliate of
the Illinois Institute of Technology, "IITRI") for additional in
vitro testing of its drug candidate, WP1122, in development as a
possible treatment for COVID-19. The testing involved a cell
viability assay in the VERO E6 cell line infected with SARS-CoV-2
and compared the therapeutic effects of 2-DG (the active ingredient
in WP1122) alone with those of WP1122, a 2-DG prodrug.
Importantly, the growth medium in this assay was carefully chosen
to reflect the levels of glucose normally found in humans rather
than the artificially high levels of glucose often used to
accelerate in vitro testing.“
“Based on feedback from the U.S. Food and Drug
Administration ("FDA"), (Moleculin) believes it
may need to demonstrate activity in a COVID-19 animal model to
successfully submit a request for Investigational New Drug
("IND") status for WP1122. In addition,
(Moleculin) has also contracted with IITRI to conduct preclinical
toxicology testing, which is currently under way.”
WPD has not conducted its own
independent confirmation testing of WP1122 and is relying solely on
the information contained in Moleculin’s news releases dated July
21, 2020 in providing this information to WPD’s
shareholders.
The Company is not making any express or implied
claims that its product has the ability to eliminate, cure or
contain the Covid-19 (or SARS-2 Coronavirus) at this time.
About WPD
Pharmaceuticals
WPD is a biotechnology research and development
company with a focus on oncology and virology, namely research and
development of medicinal products involving biological compounds
and small molecules. WPD has licensed in certain countries 10
novel drug candidates with 4 that are in clinical development
stage. These drug candidates were researched at institutions, and
WPD currently has ongoing collaborations with Wake Forest
University and leading hospitals and academic centers in
Poland.
WPD has entered into license agreements with
Wake Forest University Health Sciences and sublicense agreements
with Moleculin Biotech, Inc. and CNS Pharmaceuticals, Inc.,
respectively, each of which grant WPD an exclusive, royalty-bearing
sublicense to certain technologies of the licensor. Such agreements
provide WPD with certain research, development, manufacturing and
sales rights, among other things. The sublicense territory
from CNS Pharmaceuticals and Moleculin Biotech includes for most
compounds 30 countries in Europe and Asia, including Russia.
On Behalf of the Board
‘Mariusz Olejniczak’
Mariusz Olejniczak CEO, WPD
Pharmaceuticals
Contact:Investor RelationsEmail:
investors@wpdpharmaceuticals.comTel: 604-428-7050Web:
www.wpdpharmaceuticals.com
Cautionary
Statements:
Neither the Canadian Securities Exchange nor the
Investment Industry Regulatory Organization of Canada accepts
responsibility for the adequacy or accuracy of this release.
This press release contains forward-looking
statements. Forward-looking statements are statements that
contemplate activities, events or developments that the Company can
develop effective drugs against cancer and possibly viruses.
Factors which may prevent the forward looking statement from being
realized include that competitors or others may successfully
challenge a granted patent and the patent could be rendered void;
we may be unable to raise sufficient funding for our research; we
may be unable to expend sufficient funds on research to keep our
sublicense rights; our grant applications may not be successful or
if successful, we may not meet the requirements to receive the
grants awarded; that our drugs don’t provide positive treatment, or
if they do, the side effects are damaging; competitors may develop
better or cheaper drugs; and we may be unable to obtain regulatory
approval for any drugs we develop. Readers should refer to the risk
disclosure included from time-to-time in the documents the Company
files on SEDAR, available at www.sedar.com. Although the
Company believes that the assumptions inherent in these
forward-looking statements are reasonable, they are not guarantees
of future performance and, accordingly, they should not be relied
upon and there can be no assurance that any of them will prove to
be accurate. Finally, these forward-looking statements are
made as of the date of this press release and the Company assumes
no obligation to update them except as required by applicable
law.
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