bubka
1 week ago
One more thing. As I have said many times before, I am a longterm long here. I even added more shares after I got creamed by the 15-1 reverse split of August, 2022. I have noticed that only positive news and developments get posted here and it makes people good about their investments. That's great! But with developmental biotechs, there are always like bumps in the road, like large dilutions, time frames etc. & that kind of information doesn't get posted here.
Non-positive news is 50% of the the information that should be considered when one makes an investment with an always risky development biotech. ie all developmental biotechs are risky. The risk is why the upside can be gigantic. Without risk, the payoff would be, for the most part, priced in.
That's why I'm gonna continue to post here. If you don't like to hear the truth, then yes, put me on ignore or just ignore my posts. I regularly get called a "short"
and all kinds of other offensive names. The posters that are posting accusations about me are the ones who are posting the false information.
Think about that.
Jack Torrance
1 week ago
Correct. If people think that patients are going to walk into a doctor's office and get a tab of street-grade LSD for their condition, they are beyond wrong. Like you said, MM120 is an LSD derivative. And if approved, ONLY MM120 will be allowed to be prescribed and taken by patients. Besides being a derivative, and not 100% actual LSD, there is the requirement of potency regulations concerning prescription medications/therapies. Each dose has to be free of contamination AND very consistent with the actual content of the active ingredient. There are tons of laws and regulations about the production of FDA approved drugs. You can't just cook this stuff up in your basement. Each dose has to be 100% the same as the last, and each lot has to be the same as the last. This stuff is manufactured in a laboratory-like factories with the strictest of guidelines and regulatory oversight.
MomsSpaghetti
1 week ago
For those that want to gripe about patents... chew on this:
There are several examples in the pharmaceutical industry where drugs that could not be patented at the molecular level (often because the molecule was already known or off-patent) were successfully commercialized by patenting other aspects like formulations, delivery methods, manufacturing processes, or specific uses. Here are a few notable examples:
Prozac (Fluoxetine) • Scenario: While fluoxetine as a molecule was patentable when introduced by Eli Lilly, many of its follow-on products (like Prozac Weekly) were patented not for the molecule itself but for the controlled-release formulation. • Success: Extended exclusivity allowed Eli Lilly to maintain a market presence and differentiate from generic versions.
Lyrica (Pregabalin) • Scenario: The basic pregabalin molecule was known, but Pfizer obtained patents for its specific uses (e.g., neuropathic pain and fibromyalgia) and its crystalline structure. • Success: These patents blocked competitors and supported Lyrica’s billion-dollar revenue until generics entered after the patents expired.
Adderall (Amphetamine Salt Combo) • Scenario: Amphetamine salts were long-known substances, but Shire Pharmaceuticals patented a specific formulation and delivery mechanism that allowed a controlled release, creating Adderall XR. • Success: Adderall XR became a blockbuster drug for ADHD.
Wellbutrin XL (Bupropion) • Scenario: The molecule bupropion had already been developed, but GlaxoSmithKline patented the extended-release formulation of Wellbutrin XL to improve patient compliance and reduce side effects. • Success: The reformulation allowed the drug to become widely prescribed for depression and smoking cessation.
Suboxone (Buprenorphine/Naloxone) • Scenario: Buprenorphine is an old molecule, but Indivior patented the combination therapy with naloxone and the sublingual film formulation for opioid dependence. • Success: These innovations created market exclusivity and established Suboxone as a leading treatment in its class.
Trexall (Methotrexate) • Scenario: Methotrexate is a decades-old drug, but newer versions like Trexall leveraged formulation patents for specific dosing regimens or injectable formulations. • Success: It allowed for continued use and revenue in treating autoimmune diseases and cancers.
EpiPen (Epinephrine Auto-Injector) • Scenario: Epinephrine is not patentable, but Mylan protected the auto-injector device design and delivery system. • Success: Despite controversy over pricing, EpiPen became a household name and dominated its market.
OxyContin (Oxycodone) • Scenario: Oxycodone was already known, but Purdue Pharma patented the extended-release formulation that turned it into a controlled-release painkiller. • Success: OxyContin became highly profitable (though also controversial).
Implications for MindMed
For MM-120 (LSD), MindMed’s patents on formulations, manufacturing methods, dosing protocols, and specific therapeutic applications can provide a robust IP portfolio to protect their investment. Similar to the examples above, these protections will allow them to commercialize LSD-derived therapies despite the base molecule’s lack of patentability.