threebabiesbusy
1 week ago
https://www.biospace.com/press-releases/revive-therapeutics-advances-with-next-generation-bucillamine-development
Revive Therapeutics Advances with Next-Generation Bucillamine Development
June 4, 2025 | 4 min read
TORONTO, June 04, 2025 (GLOBE NEWSWIRE) -- Revive Therapeutics Ltd. (“Revive” or the “Company”) (OTCQB: RVVTF) (CSE: RVV) (FRANKFURT: 31R), a specialty life sciences company dedicated to developing innovative therapeutics for critical medical needs, is pleased to announce the advancement of its next-generation lyophilized formulation of Bucillamine (“New Bucillamine”). Developed in collaboration with the esteemed University of Waterloo, this breakthrough aims to address significant unmet medical needs and unlock substantial value for shareholders.
Strategic Development Targeting High-Value Opportunities
Revive is strategically positioning New Bucillamine to target public health emergencies such as pandemic influenza and emerging infectious diseases. Additionally, the company will pursue FDA incentives, including Emergency Use Authorization, Orphan Drug Designation, Fast Track, and Breakthrough Therapy designations, maximizing the potential for rapid market entry and revenue generation.
Highlighting its potential, Bucillamine, a potent antioxidant and anti-inflammatory, already boasts FDA Orphan Drug Designation for ischemia-reperfusion injury following solid organ transplantation. This designation, awarded in 2022, underscores the compound's promise and provides a pathway to accelerated development and commercialization. Furthermore, research suggests Bucillamine may enhance solid tumor treatments in cancer and the Company has been contacted by a prominent clinical researcher from a U.S. University Cancer Institute to investigate Bucillamine for boosting anti-tumor effects in patients with advanced solid tumors, potentially opening up another significant market segment.
Strong Partnerships and Ongoing Research Driving Growth
Revive is committed to fostering strong pharmaceutical and government collaborations to accelerate New Bucillamine's clinical and commercial development. Currently, the company is working with Defence R&D Canada – Suffield Research Centre (DRDC), part of the Canadian Department of National Defence, on a study evaluating Bucillamine for nerve agent exposure. Positive results, expected by June 2025, could pave the way for human clinical trials in the second half of 2025 and subsequent FDA and Health Canada approvals. The potential applications of Bucillamine extend to traumatic brain injury and viral infections, further expanding its market potential and long-term value for investors.
Revive also reports that it is continuing to work with LTS Lohmann Therapie-System AG to settle the previously announced arbitration award.
About Revive Therapeutics Ltd.
Revive Therapeutics is a specialty life sciences company dedicated to developing innovative therapeutics for critical medical needs. Revive strategically prioritizes its drug development pipeline to leverage FDA regulatory incentives like Emergency Use Authorization, Orphan Drug, Fast Track, and Breakthrough Therapy designations, positioning for rapid advancement and market entry. Currently, our efforts are concentrated on unlocking the vast potential of Bucillamine for infectious diseases and medical countermeasures, including the pioneering treatment of nerve agent exposure. Furthermore, Revive is vigorously advancing our Psilocybin and molecular hydrogen therapeutic programs, exploring new frontiers in medical science. For more information, visit www.ReviveThera.com.
For more information, please contact:
Michael Frank
Chief Executive Officer
Revive Therapeutics Ltd.
Tel: 1 888 901 0036
Email: mfrank@revivethera.com
Website: www.revivethera.com
Neither the Canadian Securities Exchange nor its Regulation Services Provider has reviewed or accepts responsibility for the adequacy or accuracy of this release.
threebabiesbusy
1 week ago
Revive Therapeutics Advances Next-Gen Bucillamine for Critical Medical Needs
TipRanks Canadian Auto-Generated Newsdesk
Jun 04, 2025, 06:42 AM
Story Highlights
Revive Therapeutics is advancing its next-gen Bucillamine for public health emergencies.
Bucillamine’s potential spans cancer treatment, nerve agent exposure, and viral infections.
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Revive Therapeutics Advances Next-Gen Bucillamine for Critical Medical Needs
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Revive Therapeutics ( RVV +20.00% ? ) has issued an update.
Revive Therapeutics Ltd. has announced the advancement of its next-generation lyophilized formulation of Bucillamine, developed in collaboration with the University of Waterloo. This new formulation targets public health emergencies and aims to leverage FDA incentives for rapid market entry. Bucillamine already holds FDA Orphan Drug Designation for ischemia-reperfusion injury and has potential applications in cancer treatment, nerve agent exposure, traumatic brain injury, and viral infections. The company is working with Defence R&D Canada on a study for nerve agent exposure, with positive results potentially leading to human trials and regulatory approvals. These developments could significantly expand Bucillamine’s market potential and long-term value for investors.
Spark’s Take on TSE:RVV Stock
According to Spark, TipRanks’ AI Analyst, TSE:RVV is a Neutral.
The overall stock score for Revive Therapeutics is primarily influenced by significant financial challenges, such as no revenue and ongoing losses. Despite this, the company demonstrates short-term bullish technical indicators and has made strategic moves to expand its pipeline through recent acquisitions and collaborations. However, the negative P/E ratio and lack of profitability remain concerns.
To see Spark’s full report on TSE:RVV stock, click here.
More about Revive Therapeutics
Revive Therapeutics Ltd. is a specialty life sciences company focused on developing innovative therapeutics for critical medical needs. The company strategically prioritizes its drug development pipeline to leverage FDA regulatory incentives, aiming for rapid advancement and market entry. Revive’s efforts are concentrated on the potential of Bucillamine for infectious diseases and medical countermeasures, as well as advancing its Psilocybin and molecular hydrogen therapeutic programs.
Average Trading Volume: 257,272
Technical Sentiment Signal: Sell
Current Market Cap: C$12.56M
See more data about RVV stock on TipRanks’ Stock Analysis page.
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threebabiesbusy
1 week ago
https://www.stocktitan.net/news/RVVTF/revive-therapeutics-advances-with-next-generation-bucillamine-hz634mnp5ipj.html
Revive Therapeutics (RVVTF) announces advancement in developing a next-generation lyophilized formulation of Bucillamine in collaboration with the University of Waterloo. The company is positioning New Bucillamine to target public health emergencies, including pandemic influenza and emerging infectious diseases. Bucillamine, which already holds FDA Orphan Drug Designation for ischemia-reperfusion injury in organ transplantation since 2022, shows promise in enhancing solid tumor treatments. The company is working with Defence R&D Canada to evaluate Bucillamine for nerve agent exposure, with results expected by June 2025. Clinical trials could begin in H2 2025, pending positive results. Revive is pursuing various FDA incentives and exploring partnerships to accelerate development and commercialization.
06/04/2025 - 05:55 AM
TORONTO, June 04, 2025 (GLOBE NEWSWIRE) -- Revive Therapeutics Ltd. (“Revive” or the “Company”) (OTCQB: RVVTF) (CSE: RVV) (FRANKFURT: 31R), a specialty life sciences company dedicated to developing innovative therapeutics for critical medical needs, is pleased to announce the advancement of its next-generation lyophilized formulation of Bucillamine (“New Bucillamine”). Developed in collaboration with the esteemed University of Waterloo, this breakthrough aims to address significant unmet medical needs and unlock substantial value for shareholders.
Strategic Development Targeting High-Value Opportunities
Revive is strategically positioning New Bucillamine to target public health emergencies such as pandemic influenza and emerging infectious diseases. Additionally, the company will pursue FDA incentives, including Emergency Use Authorization, Orphan Drug Designation, Fast Track, and Breakthrough Therapy designations, maximizing the potential for rapid market entry and revenue generation.
Highlighting its potential, Bucillamine, a potent antioxidant and anti-inflammatory, already boasts FDA Orphan Drug Designation for ischemia-reperfusion injury following solid organ transplantation. This designation, awarded in 2022, underscores the compound's promise and provides a pathway to accelerated development and commercialization. Furthermore, research suggests Bucillamine may enhance solid tumor treatments in cancer and the Company has been contacted by a prominent clinical researcher from a U.S. University Cancer Institute to investigate Bucillamine for boosting anti-tumor effects in patients with advanced solid tumors, potentially opening up another significant market segment.
Positive
FDA Orphan Drug Designation already secured for ischemia-reperfusion injury application
Potential expansion into multiple high-value markets including cancer treatment and nerve agent exposure
Ongoing collaboration with Defence R&D Canada with results expected June 2025
Strategic pursuit of multiple FDA incentives including Emergency Use Authorization and Fast Track designation
Negative
Pending arbitration settlement with LTS Lohmann Therapie-System AG
Clinical trials for nerve agent exposure application not yet started
No immediate revenue generation from current developments
GLTA!
3BB
Classic Warrior
2 months ago
One can only hope this goes up as quickly as it went down. We haven't seen any good trial news in years, just lots of letters of intent, etc. Hopefully, the trial news come out at some point, backing the relevance and anti-inflammatory nature of Bucy, $.15 with good news and support from Canada doesn't seem out of the question. .
Ecomike
2 months ago
$RVVTF more on the cancer study for using Bucillaimine
https://www.gurufocus.com/news/2771071/revive-therapeutics-to-investigate-bucillamines-potential-in-cancer-treatment-rvvtf-stock-news
Revive Therapeutics (RVVTF, Financial) to explore Bucillamine's potential in cancer treatment.
Partnership with U.S. University Cancer Institute and Defence R&D Canada for research support.
Research funded by NIH and other government entities, boosting market opportunities.
Revive Therapeutics Ltd. (OTCQB: RVVTF), a specialty life sciences company, is collaborating with a prominent researcher from a U.S. University Cancer Institute to explore the potential use of Bucillamine as a cancer treatment. The focus is on enhancing anti-tumor effects in patients with advanced solid tumors.
This initiative will be incorporated into a broader study supported by funding from the National Institutes of Health (NIH) and other government entities. The research aims to capitalize on Bucillamine's role as a thiol donor, which could neutralize reactive oxygen species and replenish reduced glutathione in the tumor microenvironment (TME), thus amplifying anti-tumor effects.
The study builds on Revive's existing partnerships, including one with Defence R&D Canada – Suffield Research Centre, focusing on Bucillamine for nerve agent exposure treatment. This multi-faceted approach highlights the compound's potential for various medical applications.
Chief Executive Officer Michael Frank expressed enthusiasm about collaborating with a leading U.S. cancer institute to validate Bucillamine's anti-inflammatory and antioxidant properties, addressing key factors that contribute to cancer progression. The study reflects Revive's commitment to discovering novel therapeutic strategies for challenging health conditions.
Ecomike
2 months ago
Here is the huge $RVVTF Cancer news, and it sounds like RVVTF is not paying for it?
https://www.biospace.com/press-releases/revive-therapeutics-to-investigate-bucillamines-potential-in-cancer-treatment
announced today that it has been contacted by a prominent clinical researcher from a U.S. University Cancer Institute. The researcher aims to investigate Bucillamine’s potential as a cancer treatment, particularly for boosting anti-tumor effects in patients with advanced solid tumors. This evaluation of Bucillamine in solid tumors would be integrated into a broader study, supported by funding from the NIH and/or other government entities. This proposed research builds on our strategy of evaluating novel uses of Bucillamine in academic and government supporting studies, including the partnership with Defence R&D Canada – Suffield Research Centre, an agency of the Canadian Department of National Defence, evaluating Bucillamine as a potential treatment for nerve agent exposure. Results from this study are expected shortly.
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