Bruker Announces Major Multi-Systems NMR Order from Vanderbilt University
20 May 2010 - 9:00PM
Business Wire
Bruker, the leader in analytical magnetic resonance
instrumentation, announces a major multi-systems NMR order from
Vanderbilt University, including an ultra-high field AVANCE™ III
900 US2 NMR spectrometer. This purchase was made possible in large
part by the American Recovery and Reinvestment Act. Vanderbilt will
use these NMR instruments for a broad range of biophysical and
structural analyses in biomedical research, as well as for cancer
drug discovery using fragment-based approaches and structure-based
drug design.
Based on Bruker’s successful 900 MHz (21.2 Tesla)
actively-shielded US² magnet, the AVANCE III 900 offers one of the
highest magnetic fields for NMR applications. The 900 US2 magnet
combines Bruker’s proprietary UltraShield™ active shielding and
UltraStabilized™ sub-cooling technologies. The result is a 900 MHz
magnet with a small footprint which can be sited within
Vanderbilt's existing NMR facility. The system includes unique
CryoProbe™ technology enabling Vanderbilt researchers to benefit
from the increased sensitivity and RF efficiency of this
cryogenically cooled NMR probe.
Vanderbilt's major NMR order includes additional AVANCE III
consoles for existing 800, 600 and 500 MHz NMR magnets, thus
creating one of the largest state-of-the-art NMR centers. The
AVANCE III is the fastest and highest performing NMR spectrometer
on the market. Its architecture delivers an unprecedented level of
digital control, speed, flexibility and exceptionally pure NMR
frequency generation. The AVANCE III’s second-generation (2G)
digital receiver (DR) technology delivers significant improvements
in NMR detection for Vanderbilt’s structural biology and drug
discovery research.
“We are ecstatic about this leap forward in our ability to
perform NMR experiments on biological macromolecules,” said Walter
Chazin, Chancellor's Professor of Biochemistry and Chemistry,
Ingram Professor of Cancer Research and Director of the Center for
Structural Biology at Vanderbilt. “The acquisition of this new
technology is critical to the cutting edge research being performed
with our NMR facilities. The addition of the new 900 MHz instrument
is especially important as it will provide enhanced capability for
our most challenging NMR projects, which study complex integral
membrane proteins, damaged genes and multi-protein machines. We
look forward to new breakthroughs in understanding the biology and
medical impact of these systems, as well as the discovery of
molecular probes and drug candidates from investigations using this
new instrumentation.”
About Bruker
For more information on NMR, please visit
www.bruker-biospin.com/nmr
For information about Bruker Corporation (NASDAQ: BRKR), please
visit www.bruker.com
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