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Upstream Bio Inc

Upstream Bio Inc (UPB)

8.94
0.52
(6.18%)
Closed 10 March 7:00AM
8.94
0.00
(0.00%)
After Hours: 11:50AM

Empower your portfolio: Real-time discussions and actionable trading ideas.

Key stats and details

Current Price
8.94
Bid
8.63
Offer
25.25
Volume
337,517
8.18 Day's Range 9.29
6.65 52 Week Range 29.35
Market Cap
Previous Close
8.42
Open
8.46
Last Trade
1
@
8.68
Last Trade Time
Financial Volume
US$ 3,032,160
VWAP
8.9837
Average Volume (3m)
335,231
Shares Outstanding
53,596,601
Dividend Yield
-
PE Ratio
-12.52
Earnings Per Share (EPS)
-0.71
Revenue
2.38M
Net Profit
-38.26M

About Upstream Bio Inc

Upstream Bio is a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. We are developing verekitug, the only known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphop... Upstream Bio is a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. We are developing verekitug, the only known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin ("TSLP"), a cytokine which is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune mediated diseases. Preclinical and clinical data to date demonstrate verekitug's highly potent inhibition of the TSLP receptor, which we believe will translate to a differentiated product profile, including improved clinical outcomes, substantially extended dosing intervals and the potential to treat a broad spectrum of patients. Show more

Sector
Pharmaceutical Preparations
Industry
Pharmaceutical Preparations
Headquarters
Wilmington, Delaware, USA
Founded
-
Upstream Bio Inc is listed in the Pharmaceutical Preparations sector of the NASDAQ with ticker UPB. The last closing price for Upstream Bio was US$8.42. Over the last year, Upstream Bio shares have traded in a share price range of US$ 6.65 to US$ 29.35.

Upstream Bio currently has 53,596,601 shares in issue. The market capitalisation of Upstream Bio is US$451.28 million. Upstream Bio has a price to earnings ratio (PE ratio) of -12.52.

UPB Latest News

PeriodChangeChange %OpenHighLowAvg. Daily VolVWAP
11.1414.61538461547.88.946.672404518.13850119CS
40.627.451923076928.328.946.652408397.81587721CS
12-11.68-56.644034917620.6221.136.6533523112.93333698CS
26-12.56-58.418604651221.529.356.6532178617.39684963CS
52-12.56-58.418604651221.529.356.6532178617.39684963CS
156-12.56-58.418604651221.529.356.6532178617.39684963CS
260-12.56-58.418604651221.529.356.6532178617.39684963CS

UPB - Frequently Asked Questions (FAQ)

What is the current Upstream Bio share price?
The current share price of Upstream Bio is US$ 8.94
How many Upstream Bio shares are in issue?
Upstream Bio has 53,596,601 shares in issue
What is the market cap of Upstream Bio?
The market capitalisation of Upstream Bio is USD 451.28M
What is the 1 year trading range for Upstream Bio share price?
Upstream Bio has traded in the range of US$ 6.65 to US$ 29.35 during the past year
What is the PE ratio of Upstream Bio?
The price to earnings ratio of Upstream Bio is -12.52
What is the cash to sales ratio of Upstream Bio?
The cash to sales ratio of Upstream Bio is 201.35
What is the reporting currency for Upstream Bio?
Upstream Bio reports financial results in USD
What is the latest annual turnover for Upstream Bio?
The latest annual turnover of Upstream Bio is USD 2.38M
What is the latest annual profit for Upstream Bio?
The latest annual profit of Upstream Bio is USD -38.26M
What is the registered address of Upstream Bio?
The registered address for Upstream Bio is 251 LITTLE FALLS DRIVE, WILMINGTON, DELAWARE, 19808
What is the Upstream Bio website address?
The website address for Upstream Bio is www.upstreambio.com
Which industry sector does Upstream Bio operate in?
Upstream Bio operates in the PHARMACEUTICAL PREPARATIONS sector

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Discussion

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learningcurve2020 learningcurve2020 2 minutes ago
Landru, That’s about the lowest bar you could possibly hope for when management gets all their shares for nothing but producing ether, and can compensate for a smaller and smaller piece of the pie while leaving their legacy shareholders down and out. 30 years and your formula has done nothing but d
NWBO
chxal chxal 3 minutes ago
Navy, the $301 BILLION repaid also does not include any settlements that were won by the FHFA, Rule of Law Guy's $63 BILLION won, my figure was $50 BILLION but it sounds like his is more accurate. When the lawsuits and settlements were taking place, I was expecting some kind of press release announ
FNMA
HappyLibrarian HappyLibrarian 3 minutes ago
His whole thesis is there is just one chance to get out and it is clearly pointed at frustrated and tired longs which is why you were targeted in my opinion with that response. For those he can’t control then the attempt to discredit and baiting with name calling takes over; ). A fairly apt student
NWBO
BOREALIS BOREALIS 3 minutes ago
Very sickening!!! 'A visitor photographs a large bust of Elon Musk near SpaceX’s Starbase'

Now the Stooge Trump will want one.
ImjinBridger ImjinBridger 5 minutes ago
if it has no relevent for the company?
The relevance is to keep people buying in. If production is actually going strong and headed for commercialization this year like he said, why would he need a pump piece to attract investors? Just give a production update. That will attract a lot more mo
KBLB
awesomed007 awesomed007 7 minutes ago
Disagree. Stock has held up during the recent downturn in the stock market. The company’s commitment has not wavered. 600 % gain last 6 months in this bad stock market is ok.
RDAR
jammy32 jammy32 9 minutes ago
Why is Nasrat jerking us around. Sell the damn company
ELTP
conix conix 9 minutes ago
Does your daughter know you are such a misogynist, arizona?

I am sad for her.
Gmenfan Gmenfan 11 minutes ago
https://media.gettr.com/group4/getter/2025/03/08/18/179bc75b-07da-1057-3b23-71ae97941cd7/e3923b64b112e89cea171617afe811c2.jpg
Gmenfan Gmenfan 11 minutes ago
https://media.gettr.com/group4/getter/2025/03/08/18/179bc75b-07da-1057-3b23-71ae97941cd7/e3923b64b112e89cea171617afe811c2.jpg
BOREALIS BOREALIS 12 minutes ago
Today in History: March 9, ‘Operation Meetinghouse’ firebombing devastates Tokyo

https://dims.apnews.com/dims4/default/69b5928/2147483647/strip/true/crop/2000x1333+0+40/resize/980x653!/format/webp/quality/90/?url=https%3A%2F%2Fassets.apnews.com%2F09%2F56%2F8f5a9ccf45bd84aeaca320a71d24
CanItBThisEZ2Make CanItBThisEZ2Make 12 minutes ago
The Special Number is now 103, now let's see if the BSR drops to align with that and my estimates :)

https://investorshub.advfn.com/uimage/uploads/2023/7/1/rfqbhSRMX_PALLET_OF_4800_VOS_56_DONGLES_JUNE_2023_with_dimensions.png

4800 - 1930 - X = 103 + 9
2870 = 10
SRMX
ilovetech ilovetech 13 minutes ago
Bingo, it must be nice for industry CEO's to be incentivized to sell shares to make their millions, irrespective of their performance. A relatively cushy desk job, with no skill set, or understanding of manufacturing required in their conventional roles. It was that glaring piece amiss from DNDN's f
NWBO
CanItBThisEZ2Make CanItBThisEZ2Make 13 minutes ago
BEST SELLERS RANK (BSR) IS 552 56 Estimated Sold on Amazon Since JAN 1 - 1ST Quarter 2025
https://investorshub.advfn.com/uimage/uploads/2024/4/24/cnxttVOS_5G_GIF.gif
https://www.amazon.com/Vos-RDGL5GX55-B-01-VOS-5G-Dongle/dp/B0C66KHZLP

NOTE: In theory, when BSR Value Dec
SRMX
navycmdr navycmdr 14 minutes ago
I simply got the Judge Lamberth plaintiff lawyer phones & emails

from previously posted public legal documents where we asked

to be PAID based on the proposed Judgement and Allocation Plan

Here is the doc w Plaintiff's lawyer phones & emails listed :
FMCC
The_Gman The_Gman 15 minutes ago
I will be, based on his original EO in 2017, his statement at the address in front of 36 million people, the creation of the Sovereign Wealth Fund, the EXIM president nominee, the EXIM appointments, the position of Congress, the appointment of Wischer, the fact that NioCorp picked it up right away i
NB
learningcurve2020 learningcurve2020 16 minutes ago
Not just any old side hustle either, but one where the cash comes from NWBO retails pockets by way of stock that depreciated 99.9+% over all these years. The fact some here have to keep brining up this point leads one to believe the disciples are really just part of the game.
NWBO
conix conix 16 minutes ago
Agreed. Common sense has been in short supply in the past four years.
luvwetscent luvwetscent 17 minutes ago
Captain, Teterboro has responded to our mayday but the transmission was garbled...we'll have to ditch, save as many souls on board as we can..been good flying with you all these years..same here"
ELTP
peanutz peanutz 18 minutes ago
We should be very close to numbers from them . Next week will be telling .
IGPK
conix conix 18 minutes ago
Exactly--the deterrence effect is to ban transgender athletes in women's sports to "deter" and discourage more crossovers.

Why are you so against fairness in women's sports? Is there some reason that you want to have more biological males competing with biological females in sports,
TucsonPhil TucsonPhil 19 minutes ago
Sure looks like a dealership to me.

https://maps.app.goo.gl/TAephZj7PDiqsbWg7

He put it on the Native American reservation; exercising a loophole to get around restrictive state laws against Tesla selling directly to customers.
TSLA
MartinLutherKing MartinLutherKing 20 minutes ago
Hold on to your dirty underwears brothers cure to cancer moment is here!! RNAZ next explosion
RNAZ
Gmenfan Gmenfan 25 minutes ago
Don't these people have anything better to do with their lives? They are a pitiful lot!!!
BigBang BigBang 25 minutes ago
Did Bray sell 30,000 sharesI may be wrong, however, I believe that he has a commitment to do so on an ongoing basis.
COOP

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