Quantum Genomics Announces Lack of Significant Efficacy for Firibastat in Their Phase III Study, FRESH and is Redirecting to New Developments
28 October 2022 - 5:00PM
Quantum Genomics (Euronext Growth - FR0011648971
- ALQGC), a biopharmaceutical company specialising in the
development of a new class of medications that directly target the
brain to treat resistant hypertension and heart failure, announces
that efficacy results for firibastat in its phase III study
FRESH, are non-significant versus placebo. These results
will be presented in detail at the AHA congress.
"Firibastat has unfortunately failed to
demonstrate significantly greater efficacy than placebo in the
phase III study FRESH. This has caused the Company to prematurely
discontinue the second phase III study, REFRESH, for ethical
reasons concerning the patients. For the same reason, in view of
these results, it has been decided to stop the development of
firibastat in cardiovascular," added Bruno Besse, Medical Director
of Quantum Genomics.
"Nevertheless, we are committed to the
mobilisation of all our strengths in the development of new
innovative treatments designed to save more lives in more patients.
It is with this in mind that we have already identified
BioTech/MedTech with whom negotiations are on-going. I wish to
thank all those who are working alongside us and those who are
supporting us towards therapeutic innovation which has always been
our mission," declared Jean-Philippe Milon, CEO of Quantum
Genomics.
"Stopping the development of firibastat in
cardiology and discontinuing the REFRESH study in particular, will
enable the Company to switch its financial horizon for the third
quarter 2023. Henceforth we will be re-allotting our funds,
amounting to 11 million euros before the discontinuation of the
REFRESH study, to the development of new innovative molecules in
unmet therapeutic domains," adds Benoit Gueugnon, Quantum Genomics
Chief Financial Officer.
All questions can be sent to:
contact@quantum-genomics.com
About Quantum GenomicsQuantum
Genomics is a biopharmaceutical company specialising in the
development of a new class of cardiovascular medications based on
brain aminopeptidase A inhibition (BAPAI). Quantum Genomics is the
only company in the world exploring this innovative approach that
directly targets the brain. It relies on over twenty years of
research conducted at Paris-Descartes University and on work
directed by Dr Catherine Llorens-Cortes at the Collège de France
(French National Institute of Health and Medical Research (INSERM)/
Scientific Centre for National Research (CNRS) laboratory). The
goal of Quantum Genomics is to develop innovative treatments for
difficult-to-treat or even resistant hypertension (hypertension is
poorly or inadequately controlled in 30% of patients) and heart
failure (one in two patients diagnosed with severe heart failure
will die within five years).
Based in Paris and New York, the company is
listed on Euronext Growth in Paris (FR0011648971- ALQGC) and trades
on the OTCQX Market in the United States (symbol: QNNTF).
For more information on
www.quantum-genomics.com, please visit our Twitter and LinkedIn
sites.
Contact information
Quantum Genomics |
|
contact@quantum-genomics.com |
|
Edifice Communication (EUROPE) |
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Financial and media
communicationsquantum-genomics@edifice-communication.com |
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LifeSci (USA) |
|
Mike TattoryMedia communications+1 (646) 751-4362 -
mtattory@lifescipublicrelations.com |
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