Vivos Inc (QB) (RDGL) Share Price

Similar but different from VIVOs and Radiogel

Molecular jackhammers' 'good vibrations' eradicate cancer cells
Light-induced whole-molecule vibration can rupture melanoma cells' membrane
Date:
December 19, 2023
Source:
Rice University
Summary:
Scientists have found a new way to kill cancer cells by using near-infrared light to make a small dye molecule attached to their membrane vibrate strongly.


FULL STORY
The Beach Boys' iconic hit single "Good Vibrations" takes on a whole new layer of meaning thanks to a recent discovery by Rice University scientists and collaborators, who have uncovered a way to destroy cancer cells by using the ability of some molecules to vibrate strongly when stimulated by light.

The researchers found that the atoms of a small dye molecule used for medical imaging can vibrate in unison - forming what is known as a plasmon - when stimulated by near-infrared light, causing the cell membrane of cancerous cells to rupture. According to the study published in Nature Chemistry, the method had a 99 percent efficiency against lab cultures of human melanoma cells, and half of the mice with melanoma tumors became cancer-free after treatment.

"It is a whole new generation of molecular machines that we call molecular jackhammers," said Rice chemist James Tour, whose lab has previously used nanoscale compounds endowed with a light-activated paddlelike chain of atoms that spins continually in the same direction to drill through the outer membrane of infectious bacteria, cancer cells and treatment-resistant fungi.



Unlike the nanoscale drills based on Nobel laureate Bernard Feringa's molecular motors, molecular jackhammers employ an entirely different - and unprecedented - mechanism of action.

"They are more than one million times faster in their mechanical motion than the former Feringa-type motors, and they can be activated with near-infrared light rather than visible light," Tour said.

Near-infrared light can penetrate far deeper into the body than visible light, accessing organs or bones without damaging tissue.

"Near-infrared light can go as deep as 10 centimeters (~ 4 inches) into the human body as opposed to only half a centimeter (~ 0.2 inches), the depth of penetration for visible light, which we used to activate the nanodrills," said Tour, Rice's T. T. and W. F. Chao Professor of Chemistry and a professor of materials science and nanoengineering. "It is a huge advance."

The jackhammers are aminocyanine molecules, a class of fluorescent synthetic dyes used for medical imaging.

"These molecules are simple dyes that people have been using for a long time," said Ciceron Ayala-Orozco, a Rice research scientist who is a lead author on the study. "They're biocompatible, stable in water and very good at attaching themselves to the fatty outer lining of cells. But even though they were being used for imaging, people did not know how to activate these as plasmons."

Ayala-Orozco initially studied plasmons as a doctoral student in the research group led by Rice's Naomi Halas.



"Due to their structure and chemical properties, the nuclei of these molecules can oscillate in sync when exposed to the right stimulus," Ayala-Orozco said. "I saw a need to use the properties of plasmons as a form of treatment and was interested in Dr. Tour's mechanical approach to dealing with cancer cells. I basically connected the dots.

"The molecular plasmons we identified have a near-symmetrical structure with an arm on one side. The arm doesn't contribute to the plasmonic motion, but it helps anchor the molecule to the lipid bilayer of the cell membrane."

The researchers had to prove that the molecules' mode of action could not be categorized either as a form of photodynamic or photothermal therapy.

"What needs to be highlighted is that we've discovered another explanation for how these molecules can work," Ayala-Orozco said. "This is the first time a molecular plasmon is utilized in this way to excite the whole molecule and to actually produce mechanical action used to achieve a particular goal ? in this case, tearing apart cancer cells' membrane.

"This study is about a different way to treat cancer using mechanical forces at the molecular scale."

Researchers at Texas A&M University led by Jorge Seminario, a quantum chemist and professor of chemical engineering, performed time-dependent density functional theory analysis on the molecular features involved in the jackhammering effect. The cancer studies were performed in mice at the University of Texas MD Anderson Cancer Center in collaboration with Dr. Jeffrey Myers, professor and chair of the Department of Head and Neck Surgery and director of translational research for the Division of Surgery.







Materials provided by Rice University. Note: Content may be edited for style and length.

Journal Reference:

Ciceron Ayala-Orozco, Diego Galvez-Aranda, Arnoldo Corona, Jorge M. Seminario, Roberto Rangel, Jeffrey N. Myers, James M. Tour. Molecular jackhammers eradicate cancer cells by vibronic-driven action. Nature Chemistry, 2023; DOI: 10.1038/s41557-023-01383-y

Rice University. "Molecular jackhammers' 'good vibrations' eradicate cancer cells." ScienceDaily. ScienceDaily, 19 December 2023.

https://www.sciencedaily.com/releases/2023/12/231219182301.htm

Splintered Sunlight = johnnytrader33

$5

Thought I would paint the tape at the close. Those were mine at 0.12.

I agree with this .   Fireworks may come earlier than July . They've been very quiet 

You believe that because you lack basic literacy skills.

Keep at it and you'll eventually understand......maybe!?!

I was trying to negate your point.

You didn't have a point to negate.

Nice post and logical!!

Now, if someone would just light the fuze!!

Food for thought: The recent quiet period might seem concerning, but if you look at past major announcements from bio-tech players, it's often a positive sign in the biotech world. 
When companies go "dark" before major announcements, especially regarding clinical trial results, like their India trials, or regulatory submissions, such as their IDE, it usually means they're intensely focused on finalizing critical data, undergoing rigorous regulatory and legal reviews, and strategically planning the release of information. To me it signals they are being careful to not inadvertently release info or make claims before the official news. 
Given Vivos' past positive updates on the safety of their India trials and the ongoing work for their IDE, this silence most likely indicates they are diligently working behind the scenes to prepare a comprehensive and impactful announcement. 
This is a common pattern for companies nearing a significant breakthrough; they go quiet to ensure everything is perfect before sharing big news. Investors should keep an eye on official company communications for updates.
This is a good time to load up. As we saw with the Christmas Eve update, they like to drop major news out of the blue... then the share price rockets up 

LATE but back at you and ALL fathers
We had a big ol storm Sun morning and someone hydroplaned and hit a telephone pole and a big 4x4 phone junction box at about 4:30 am took out all internet and electric for the day

Aaaah, mid-June, we are within the 30 day window of some significant events for us starting this week!

I hope all you Dad's out there enjoyed your Father's Day weekend!

-Go $RDGL

Happy Father's Day.

Nothing you posted negates my point that you're absurd references to past events have little to no bearing on our current situation.

Except the same speculations have always been there.

SSDD

This is just a different variant.

BTW, I hope you are right and this is different.

I would love to sell my stock, make a killing and move on.

RDGL, please make me congratulate everyone and never post on this board ever again!!!!!!!!!!!!!!!!!!!!

I would love you to prove what you posted.

Please

Take your time.

I'll disappear once RDGL actually goes up a significant amount and stays there.

Hopefully tomorrow!!!!!!!!!

In your world probably never.........

AIMHO......I believe we begin experiencing a general upward trend in the PPS later this week, or early the next in anticipation of the July 14th deadline for IDE submission.

An substantive update from Vivos would definitely increase the likelihood of this occurring.

GLTA

"The Vivos team is currently in India to compile important data for our IDE submission. After understanding the hospital’s policy of sharing patient photos and interviews we are just gathering the content to show when advised. We appreciate your support! $RDGL"

The Vivos team is currently in India to compile important data for our IDE submission. After understanding the hospital’s policy of sharing patient photos and interviews we are just gathering the content to show when advised. We appreciate your support! $RDGL pic.twitter.com/RhBukNpW1M— RadioGel® (@RadioGel) May 27, 2025

For some reason, i have a feeling, there will be some communications this coming week. 

To All Father Longs: Happy Fathers Day, to include myself. RDGL $$$.

Has Vivos gone dark since trip to India? I havent seen anything not even an isopet tweet.

The Complain-Ticons on here are hilarious, and perplexing.......nothing but whingeing and snide commentary ad nauseam.

One would think if owning Vivos was that bothersome they would do themselves the simple service of liquidating their positions and carrying on with their respective lives, but alas......

This is exactly what you posted.......

Quote: "This been a hair away from submission/approval/$5/$6..... for years now........"

An analogy would be a young unemployed man telling everyone that he will one day own a Mansion and a fleet of Sports cars. At some point, many years later, after much hard work he created a valuable product that became very successful and he was finally able to fulfill the goals he wasn't in a position to before.

My point being, all that you heard from posters/Vivos in the past has zero bearing on the possibilities today because the company is now in a groundbreaking position that it was never in before, ie, completed FDA discussions, conducting Trials and has set a firm date for submission.

I believe we are all fully aware that Vivos's IDE needs to be submitted and approved before all our lofty hopes become reality but the fact remains we have NEVER been in this unique position before today so any reference, and/or comparison to the past is simply inane.

He is also the Loanranger, aBrooklyn, frenchbroad, hedges 54, Iglow, SC8, musical shares, portuguese ham, surfkast, koolaidman, homebrew, Researchfyi, Edward, price_and volume --- plus many many more.

To go back to splintered sunlight:

Let me also add that he posted 47, 786 comments on one board and 5,960 on another---- This means severe dishonesty and attempted stock manipulation. All of the posts are often times pretend conversations between one person and fake screen names via IP moving software.

Definition of soon is the answer to "when will you disappear again?"
Bye

Soon.

Would love to hear your definition of soon.

Soon has to be at least years..........

Each and every day!!!!!!!!

I think you are way low.

Could be 1,000's.

Good thing is, the sun will aways come up tomorrow and next week RDGL will begin to run.

So true................

Yup

Just like you been saying for years now..............

Long gone, LOL.

BTW, truly hope you are right!!!!!!!!!!!!

Your post does nothing to refute my post.

I have been reading on this board exactly what I posted and I am still reading the same things irrespective of extensive discussions re IDA via Spirit Meetings............

Either they submit and get approved or they submit and they don't get approved or what has been the case, they keep taking about submitting and the people on this board endlessly cheerlead.

Yes, I know so!!!!!!!!!!!!!!!!!!!!!!!!!

How many years have you been saying this konshe?

Looks like someone is selling around 2600 shares every 18 minutes . Prob a market maker . Only way to increase the share price is to raise the bid . These OTC  games will be over soon 

Broken clock is right twice a day 

Great interview with the new FDA Commissioner about streamlining the system and shortening the Drug approval process. This could help Vivos once we get results from India.



9:00 OxyContin
11:00 New Drug Approvals Process
23:30 Big Pharma
26:00 Lobbyists & The Swamp
29:00 Food Additives
31:00 Animal Testing Vs New Methods
33:00 Shorter Drug Approvals Process
39:00 Food Labels
40:00 Autism & Microbiome
43:00 Microbiome Explanation
45:00 Children’s Health
49:00 Fix Microbiome
54:00 Animal Testing
57:00 Doge Cuts

Heard this about 100 times since investing in Rdgl five years ago lol 

Today is last day to buy at cheap, next week RDGL will begin to run.

Re the evidence cited from the DOD, and general data in the vid.

Was being sarcastic....see post# 189027.

pretty much.. still feeling it..

Vivos investor Life spent between 
Thank you for the cheapies.&Soon these prices will be gone.

DOC
I agree, if if IFIN they file it timely.

About 30 or so days till IDE submission?   These prices will be long gone . 

The stock has been in cruise control for a while, but now that we're just weeks away I expect things to pick up soon.

Hotmeat
OF WHAT

IDE hasn't been submitted yet so I'm not sure what FDA news you're referring to.

Not one shred of EVIDENCE BOB..................



100% Safe and Effective

I was hoping on some major deals to go through to get to that $1. FDA news wasnt what we thought

At what point during the last decade has Vivos previously engaged in extensive discussions re IDE with the FDA via Sprint Meetings and was conducting a Clinical Trial on Radiogel in any jurisdiction, foreign or domestic!?!

Oh yes, I thought so........................

Looks like RDGL is ready to go up,See green Tomorrow MMs will change the direction to run north until big gap up next month.