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RNS Number : 8322B

Silence Therapeutics PLC

12 October 2020

Director Dealing

12 October 2020

LONDON, Silence Therapeutics plc, AIM:SLN and Nasdaq: SLN ("Silence" or "the Company"), a leader in the discovery, development and delivery of novel short interfering ribonucleic acid (siRNA) therapeutics for the treatment of diseases with significant unmet medical need, today announces that, on the 8th and 9th October 2020, 9,750 Shares were purchased by Iain Ross, Chairman of the Company, through his self-invested personal pension (SIPP) at GBP4.10 per share, 1,250 Shares were purchased by David Lemus, Non-Executive Director of the Company, at GBP4.00 per share, 3,000 Shares were purchased by James Ede-Golightly, Non-Executive Director of the Company, at GBP4.09 per share, and 4,945 Shares were purchased by Dr. Giles Campion, Executive Director of the Company, at GBP4.04 per share.

Following this purchase, Iain Ross is interested in 54,443 ordinary shares (0.07%) of the issued share capital of the Company, David Lemus is interested in 6,876 ordinary shares (0.01%) of the issued share capital of the Company, James Ede-Golightly is interested in 3,000 ordinary shares (0.00%) of the issued share capital of the Company, and Dr. Giles Campion is interested in 14,945 ordinary shares (0.02%) of the issued share capital of the Company.

Notification and public disclosure of transactions by persons discharging managerial responsibilities and persons closely associated with them

 
 1.   Details of the person discharging managerial responsibilities 
       (PDMR) / person closely associated 
 a)   Name                         Iain Ross 
     ---------------------------  -------------------------------------------- 
 2.   Reason for the notification 
     ------------------------------------------------------------------------- 
 a)   Position / status            Chairman 
     ---------------------------  -------------------------------------------- 
 b)   Initial notification         Initial notification 
       / Amendment 
     ---------------------------  -------------------------------------------- 
 3.   Details of the issuer, emission allowance market participant, 
       auction platform, auctioneer or auction monitor 
     ------------------------------------------------------------------------- 
 a)   Name                         Silence Therapeutics plc 
     ---------------------------  -------------------------------------------- 
 b)   LEI                          213800SSURRJBX85SQ91 
     ---------------------------  -------------------------------------------- 
 4    Details of the transaction(s): section to be repeated for 
       (i) each type of instrument; (ii) each type of transaction; 
       (iii) each date; and (iv) each place where transactions 
       have been conducted 
     ------------------------------------------------------------------------- 
 a)   Description of               Ordinary Shares of 5 pence each in Silence 
       the financial instrument,    Therapeutics plc 
       type of instrument 
 
       Identification 
       code                         ISIN for Silence Therapeutics plc Ordinary 
                                    Shares: 
                                    GB00B9GTXM62 
     ---------------------------  -------------------------------------------- 
 b)   Nature of the transaction    Purchase of Ordinary Shares in Silence 
                                    Therapeutics plc 
     ---------------------------  -------------------------------------------- 
 c)   Prices(a) and volume(s)        Price      Volume 
                                      GBP4.10    9,750 
                                                ------- 
     ---------------------------  -------------------------------------------- 
 d)   Aggregated information 
       - Aggregated volume           9,750 Ordinary Shares 
       - Price                       GBP39,976.00 
     ---------------------------  -------------------------------------------- 
 e)   Date of the transaction      8 October 2020 
     ---------------------------  -------------------------------------------- 
 f)   Place of the transaction     London Stock Exchange, AIM 
     ---------------------------  -------------------------------------------- 
 
 
 1.   Details of the person discharging managerial responsibilities 
       (PDMR) / person closely associated 
 a)   Name                         David Lemus 
     ---------------------------  -------------------------------------------- 
 2.   Reason for the notification 
     ------------------------------------------------------------------------- 
 a)   Position / status            Non-Executive Director 
     ---------------------------  -------------------------------------------- 
 b)   Initial notification         Initial notification 
       / Amendment 
     ---------------------------  -------------------------------------------- 
 3.   Details of the issuer, emission allowance market participant, 
       auction platform, auctioneer or auction monitor 
     ------------------------------------------------------------------------- 
 a)   Name                         Silence Therapeutics plc 
     ---------------------------  -------------------------------------------- 
 b)   LEI                          213800SSURRJBX85SQ91 
     ---------------------------  -------------------------------------------- 
 4    Details of the transaction(s): section to be repeated for 
       (i) each type of instrument; (ii) each type of transaction; 
       (iii) each date; and (iv) each place where transactions 
       have been conducted 
     ------------------------------------------------------------------------- 
 a)   Description of               Ordinary Shares of 5 pence each in Silence 
       the financial instrument,    Therapeutics plc 
       type of instrument 
 
       Identification 
       code                         ISIN for Silence Therapeutics plc Ordinary 
                                    Shares: 
                                    GB00B9GTXM62 
     ---------------------------  -------------------------------------------- 
 b)   Nature of the transaction    Purchase of Ordinary Shares in Silence 
                                    Therapeutics plc 
     ---------------------------  -------------------------------------------- 
 c)   Prices(a) and volume(s)        Price      Volume 
                                      GBP4.00    1,250 
                                                ------- 
     ---------------------------  -------------------------------------------- 
 d)   Aggregated information 
       - Aggregated volume           1,250 Ordinary Shares 
       - Price                       GBP5,000.00 
     ---------------------------  -------------------------------------------- 
 e)   Date of the transaction      9 October 2020 
     ---------------------------  -------------------------------------------- 
 f)   Place of the transaction     London Stock Exchange, AIM 
     ---------------------------  -------------------------------------------- 
 
 
 1.   Details of the person discharging managerial responsibilities 
       (PDMR) / person closely associated 
 a)   Name                         James Ede-Golightly 
     ---------------------------  -------------------------------------------- 
 2.   Reason for the notification 
     ------------------------------------------------------------------------- 
 a)   Position / status            Non-Executive Director 
     ---------------------------  -------------------------------------------- 
 b)   Initial notification         Initial notification 
       / Amendment 
     ---------------------------  -------------------------------------------- 
 3.   Details of the issuer, emission allowance market participant, 
       auction platform, auctioneer or auction monitor 
     ------------------------------------------------------------------------- 
 a)   Name                         Silence Therapeutics plc 
     ---------------------------  -------------------------------------------- 
 b)   LEI                          213800SSURRJBX85SQ91 
     ---------------------------  -------------------------------------------- 
 4    Details of the transaction(s): section to be repeated for 
       (i) each type of instrument; (ii) each type of transaction; 
       (iii) each date; and (iv) each place where transactions 
       have been conducted 
     ------------------------------------------------------------------------- 
 a)   Description of               Ordinary Shares of 5 pence each in Silence 
       the financial instrument,    Therapeutics plc 
       type of instrument 
 
       Identification 
       code                         ISIN for Silence Therapeutics plc Ordinary 
                                    Shares: 
                                    GB00B9GTXM62 
     ---------------------------  -------------------------------------------- 
 b)   Nature of the transaction    Purchase of Ordinary Shares in Silence 
                                    Therapeutics plc 
     ---------------------------  -------------------------------------------- 
 c)   Prices(a) and volume(s)        Price        Volume 
                                      GBP4.0875    3,000 
                                                  ------- 
     ---------------------------  -------------------------------------------- 
 d)   Aggregated information 
       - Aggregated volume           3,000 Ordinary Shares 
       - Price                       GBP12,262.50 
     ---------------------------  -------------------------------------------- 
 e)   Date of the transaction      8 October 2020 
     ---------------------------  -------------------------------------------- 
 f)   Place of the transaction     London Stock Exchange, AIM 
     ---------------------------  -------------------------------------------- 
 
 
 1.   Details of the person discharging managerial responsibilities 
       (PDMR) / person closely associated 
 a)   Name                         Dr. Giles Campion 
     ---------------------------  -------------------------------------------- 
 2.   Reason for the notification 
     ------------------------------------------------------------------------- 
 a)   Position / status            Executive Director 
     ---------------------------  -------------------------------------------- 
 b)   Initial notification         Initial notification 
       / Amendment 
     ---------------------------  -------------------------------------------- 
 3.   Details of the issuer, emission allowance market participant, 
       auction platform, auctioneer or auction monitor 
     ------------------------------------------------------------------------- 
 a)   Name                         Silence Therapeutics plc 
     ---------------------------  -------------------------------------------- 
 b)   LEI                          213800SSURRJBX85SQ91 
     ---------------------------  -------------------------------------------- 
 4    Details of the transaction(s): section to be repeated for 
       (i) each type of instrument; (ii) each type of transaction; 
       (iii) each date; and (iv) each place where transactions 
       have been conducted 
     ------------------------------------------------------------------------- 
 a)   Description of               Ordinary Shares of 5 pence each in Silence 
       the financial instrument,    Therapeutics plc 
       type of instrument 
 
       Identification 
       code                         ISIN for Silence Therapeutics plc Ordinary 
                                    Shares: 
                                    GB00B9GTXM62 
     ---------------------------  -------------------------------------------- 
 b)   Nature of the transaction    Purchase of Ordinary Shares in Silence 
                                    Therapeutics plc 
     ---------------------------  -------------------------------------------- 
 c)   Prices(a) and volume(s)        Price      Volume 
                                      GBP4.04    4,945 
                                                ------- 
     ---------------------------  -------------------------------------------- 
 d)   Aggregated information 
       - Aggregated volume           4,945 Ordinary Shares 
       - Price                       GBP19,977.80 
     ---------------------------  -------------------------------------------- 
 e)   Date of the transaction      9 October 2020 
     ---------------------------  -------------------------------------------- 
 f)   Place of the transaction     London Stock Exchange, AIM 
     ---------------------------  -------------------------------------------- 
 

Enquiries:

 
 Silence Therapeutics plc                              Tel: +1 (646) 637-3208 
  Gem Hopkins, Head of IR & Corporate Communications 
  Investec Bank plc (Nominated Adviser and              Tel: +44 (0) 20 
   Broker)                                               7597 5970 
   Daniel Adams/Gary Clarence 
 European IR                                           Tel: +44 (0) 20 
  Consilium Strategic Communications                    3709 5700 
  Mary-Jane Elliott/Chris Welsh/Angela Gray 
  silencetherapeutics@consilium-comms.com 
 US IR                                                  Tel: +1 (443) 213-0505 
  Westwicke Partners 
  Peter Vozzo 
  peter.vozzo@westwicke.com 
 

About Silence Therapeutics plc

Silence Therapeutics is developing a new generation of medicines by harnessing the body's natural mechanism of RNA interference, or RNAi, to inhibit the expression of specific target genes thought to play a role in the pathology of diseases with significant unmet medical need. Silence's proprietary technology can be used to engineer short interfering ribonucleic acids (siRNAs) that bind specifically to and silence, through the RNAi pathway, almost any gene in the human genome to which siRNA can be delivered. Silence's wholly owned product candidates include SLN360 designed to address the high and prevalent unmet medical need in reducing cardiovascular risk in people born with high levels of Lipoprotein(a) and SLN124 to address beta-thalassemia and myelodysplastic syndrome. Silence is also developing a C3 targeting programme, SLN500, in partnership with Mallinckrodt Pharmaceuticals to reduce the expression of the C3 protein for the treatment of complement pathway-mediated diseases. Silence maintains ongoing research and collaborations with AstraZeneca, Mallinckrodt Pharmaceuticals and Takeda. For more information, please visit: https://www.silence-therapeutics.com/

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