FORM 4 [X] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Chao Jennifer M		 2. Issuer Name and Ticker or Trading Symbol

BIOSPECIFICS TECHNOLOGIES CORP [ BSTC ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__X__ Director                    _____ 10% Owner
_____ Officer (give title below)    _____ Other (specify below)
(Last)          (First)          (Middle)

C/O BIOSPECIFICS TECHNOLOGIES CORP., 2 RIGHTER PKWY, DE CORP CENTER II		 3. Date of Earliest Transaction (MM/DD/YYYY)

12/2/2020
(Street)

WILMINGTON, DE 19803
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
 6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock, $0.001 par value 12/2/2020  D  1920 D (1)1726 D  
Common Stock, $0.001 par value 12/2/2020  D  1726 D (2)0 D  

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)		2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)		8. Price of Derivative Security
(Instr. 5)		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (Right to Buy) $37.64 12/2/2020  D     1687   (3)4/22/2025 Common Stock 1687 $50.86 20000 D  
Stock Option (Right to Buy) $41.82 12/2/2020  D     15000   (4)3/15/2028 Common Stock 15000 $46.68 5000 D  
Stock Option (Right to Buy) $55.62 12/2/2020  D     5000   (5)3/13/2030 Common Stock 5000 $32.88 0 D  
Explanation of Responses:
(1) Upon the consummation of the merger (the "Merger") contemplated by that certain Agreement and Plan of Merger, by and among BioSpecifics Technologies Corp., Endo International plc, and Beta Acquisition Corp., dated October 19, 2020 (the "Merger Agreement"), 1,920 shares of common stock were exchanged for a cash payment of $169,920.00, representing the product obtained by multiplying the offer price ($88.50) by the number of shares owned by the reporting person.
(2) Upon the consummation of the Merger, pursuant to the Merger Agreement, 1,726 outstanding restricted stock units ("RSUs") were canceled in exchange for a cash payment of $152,751.00, representing the product obtained by multiplying (x) the aggregate number of shares of common stock underlying the RSUs, by (y) the offer price ($88.50).
(3) Upon the consummation of the Merger, pursuant to the Merger Agreement, the stock options, which provided for vesting in four equal annual installments following the grant date (April 22, 2015), were canceled in exchange for a cash payment of $85,800.82, representing the product obtained by multiplying (x) the aggregate number of shares of common stock underlying the stock options by (y) the amount by which the offer price ($88.50) exceeds the per share exercise price of such stock option.
(4) Upon the consummation of the Merger, pursuant to the Merger Agreement, the stock options, which provided for vesting in four equal annual installments following the grant date (March 15, 2018), were canceled in exchange for a cash payment of $700,200.00, representing the product obtained by multiplying (x) the aggregate number of shares of common stock underlying the stock options by (y) the amount by which the offer price ($88.50) exceeds the per share exercise price of such stock option.
(5) Upon the consummation of the Merger, pursuant to the Merger Agreement, the stock options, which would have vested in full on the one-year anniversary of the grant date (March 13, 2020), were canceled in exchange for a cash payment of $164,400.00, representing the product obtained by multiplying (x) the aggregate number of shares of common stock underlying the stock options by (y) the amount by which the offer price ($88.50) exceeds the per share exercise price of such stock option.
Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Chao Jennifer M
C/O BIOSPECIFICS TECHNOLOGIES CORP.
2 RIGHTER PKWY, DE CORP CENTER II
WILMINGTON, DE 19803		X
Signatures
/s/ Jennifer M. Chao, by Carl A. Valenstein, attorney-in-fact12/2/2020
**Signature of Reporting PersonDate
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