FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public
Utility Holding Company Act of 1935 or Section 30(f) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Erck Stanley C 		2. Issuer Name and Ticker or Trading Symbol

IOMAI CORP [ IOMI ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                      _____ 10% Owner
__ X __ Officer (give title below)      _____ Other (specify below)
President & CEO
(Last)          (First)          (Middle)

20 FIRSTFIELD ROAD 		3. Date of Earliest Transaction (MM/DD/YYYY)

7/29/2008
(Street)

GAITHERSBURG, MD 20878
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   7/29/2008     M    2901   A $5.51   27901   D    
Common Stock   7/29/2008     M    5300   A $4.95   33201   D    
Common Stock   7/29/2008     S    8200   D $6.55   25001   D    
Common Stock   7/30/2008     M    79086   A $5.51   104087   D    
Common Stock   7/30/2008     M    50950   A $4.95   155037   D    
Common Stock   7/30/2008     S    59101   D $6.55   95936   D    
Common Stock   7/30/2008     S    66313   D $6.56   29623   D    
Common Stock   7/30/2008     S    4622   D $6.57   25001   D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock option (right to buy)   $5.51   7/29/2008     M        2901      (1) 2/16/2016   Common Stock   2901   $0.00   247099   D    
Stock option (right to buy)   $4.95   7/29/2008     M        5300      (2) 3/6/2017   Common Stock   5300   $0.00   219700   D    
Stock option (right to buy)   $5.51   7/30/2008     M        79086      (1) 2/16/2016   Common Stock   79086   $0.00   168013   D    
Stock option (right to buy)   $4.95   7/30/2008     M        50950      (2) 3/6/2017   Common Stock   50950   $0.00   168750   D    

Explanation of Responses:
( 1)  The option vests in four equal installments of 62,500 shares each on February 16, 2007, 2008, 2009 and 2010.
( 2)  The option vests in four equal installments of 56,250 shares each on March 6, 2008, 2009, 2010 and 2011.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Erck Stanley C
20 FIRSTFIELD ROAD
GAITHERSBURG, MD 20878 		X
President & CEO

Signatures
/s/ Stanley C. Erck 7/31/2008
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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