As filed with the Securities and Exchange
Commission on November 26, 2014
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NORTHWEST
BIOTHERAPEUTICS, INC.
NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
TO BE HELD ON DECEMBER 19, 2014
Dear Stockholder:
You are hereby cordially invited to attend
the 2014 Annual Meeting of Stockholders of Northwest Biotherapeutics, Inc., which will be held on Friday, December 19, 2014 at
10:00 a.m. (local time) at the offices Gibson, Dunn and Crutcher LLP, 1050 Connecticut Avenue, NW, 2nd Floor, Washington,
DC 20036, and any adjournments or postponements of the annual meeting.
We are holding the annual meeting for
the following purposes:
| 1. | To elect two members to our Board of Directors to serve as Class II directors for a term of three years; |
| 2. | To hold an advisory vote on executive compensation; |
| 3. | To hold an advisory vote on the frequency with which future advisory votes on executive compensation should be held; |
| 4. | To ratify the appointment of Marcum LLP as our independent registered public accounting firm for the fiscal year ending December 31,
2014; and |
| 5. | To act upon such other matters as may properly come before the meeting or any adjournment thereof. |
These matters are more fully described
in the attached proxy statement, which is made a part of this notice. At this point, we are not aware of any other business to
be transacted at the annual meeting.
Only stockholders of record on our books
at the close of business on Friday, November 14, 2014 will be entitled to vote at the annual meeting and any adjournments or postponements
of the annual meeting. For 10 days prior to the annual meeting, a list of stockholders entitled to vote will be available
for inspection at our principal executive offices located at 4800 Montgomery Lane, Suite 800, Bethesda, Maryland 20814. This list
also will be available for inspection at the annual meeting. If you would like to view the stockholder list, please call our executive
offices at (240) 497-9024 to schedule an appointment.
A copy of our 2013 Annual Report on Form
10-K, which contains our consolidated financial statements for the fiscal year ended December 31, 2013, and other information
of interest to stockholders, accompanies this notice and the attached proxy statement. This notice, the attached proxy statement
and our 2013 Annual Report on Form 10-K for the fiscal year ended December 31, 2013 are also available, free of charge, in PDF
and HTML format at http://www.edocumentview.com/NWBO and will remain posted on this website at least until the conclusion
of the meeting.
By Order of the Board of Directors, |
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/s/Linda F. Powers |
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Chairperson of the Board of Directors |
November 26, 2014
WHETHER OR NOT YOU PLAN TO ATTEND THE MEETING, PLEASE PROMPTLY COMPLETE, SIGN, DATE AND RETURN THE ENCLOSED PROXY CARD IN THE ACCOMPANYING ENVELOPE. NO POSTAGE NEED BE AFFIXED IF THE PROXY CARD IS MAILED IN THE UNITED STATES. |
NORTHWEST
BIOTHERAPEUTICS, INC.
4800 Montgomery Lane
Suite 800
Bethesda, Maryland 20814
PROXY STATEMENT
FOR THE ANNUAL MEETING OF STOCKHOLDERS
TO BE HELD ON DECEMBER 19, 2014
This proxy statement is being furnished
in connection with the solicitation of proxies by the Board of Directors of Northwest Biotherapeutics, Inc. (“we,”
“us,” “our” or the “Company”), for use at the 2014 Annual Meeting of Stockholders to be held
on Friday, December 19, 2014 at 10:00 a.m. (local time) at the law firm of Gibson, Dunn and Crutcher LLP, 1050 Connecticut
Avenue, NW, 2nd Floor, Washington, DC 20036, and any adjournments or postponements of the annual meeting. The Board
of Directors, or the Board, is soliciting proxies for the purposes set forth in the accompanying Notice of Annual Meeting of Stockholders.
Record Date and Share Ownership
Only stockholders of record on our books
at the close of business on Friday, November 14, 2014 will be entitled to vote at the annual meeting and any adjournments
or postponements of the annual meeting. As of the close of business on November 14, 2014, we had 64,504,106 shares of common
stock outstanding. Each share of common stock entitles the record holder to one vote on each matter to be voted upon at the annual
meeting. Copies of the Notice of Annual Meeting of Stockholders, this proxy statement, the enclosed proxy card and our Annual
Report on Form 10-K for the fiscal year ended December 31, 2013, will be mailed to stockholders of record on or about November
26, 2014. Exhibits to the Annual Report will be provided to any stockholder at no charge upon written or oral request to our corporate
secretary at the address set forth under “Communication with the Board of Directors” below.
Voting in Person
If you plan to attend the meeting and
vote in person, we will provide a ballot to you when you arrive. However, if you hold your shares in the name of a broker, bank
or other nominee, you must bring an account statement or letter from the nominee indicating that you were the beneficial owner
of the shares on November 14, 2014, the record date for voting.
Voting by Proxy
Shares represented by a properly executed
proxy in the form that accompanies this proxy statement will be voted at the annual meeting and, if you provide instructions on
the proxy, will be voted in accordance with those instructions. If you hold shares in your own name, you may vote by proxy by accessing
the proxy materials on the secured website http://www.investorvote.com/NWBO and following the voting instructions on that
website. If you do not provide instructions as to how your shares should be voted, your shares will be voted according to the recommendations
of our Board as follows:
| • | FOR the election of Robert A. Farmer and Jerry
Jasinowski, as the Class II directors; |
| • | FOR, on an advisory basis, the Company’s
executive compensation; |
| • | FOR, on an advisory basis, the option of every
three years as the frequency with which stockholders are provided an advisory vote on executive compensation; and |
| • | FOR the ratification of the appointment of Marcum
LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2014. |
If other matters come before the annual
meeting, the persons named as proxy will vote on such matters in accordance with his or her best judgment. We have not received
any notice of other matters that may properly be presented at the annual meeting. We bear the expense of soliciting proxies. Our
directors, officers or employees may also solicit proxies personally or by telephone, e-mail, facsimile or other means of communication.
We do not intend to pay additional compensation for doing so. We might reimburse banks, brokerage firms and other custodians, nominees
and fiduciaries representing beneficial owners of our common stock, for their expenses in forwarding soliciting materials to those
beneficial owners.
Revoking a Proxy
You may revoke your proxy at any time
prior to the start of the annual meeting by delivering written instructions to our corporate secretary at the address set forth
under “Communication with the Board of Directors” below. Attendance at the annual meeting will not itself be
deemed to revoke your proxy unless you give notice at the annual meeting that you intend to revoke your proxy and vote in person.
If you are a beneficial owner of shares held in “street name,” you may submit new voting instructions by contacting
your broker, bank or other nominee.
Quorum Required
A quorum of stockholders is necessary
to hold a valid meeting. A majority of shares entitled to vote on the election of directors at the annual meeting present in person
or represented by proxy represents a quorum. Shares which abstain from voting on a particular matter and “broker non-votes,”
or shares held in “street name” by brokers, banks or other nominees who indicate on their proxies that they do not
have discretionary authority to vote such shares on a particular matter, are counted for purposes of determining whether a quorum
exists.
Votes Required
Each stockholder is entitled to one vote
for each share of common stock held on all matters to be voted on at the annual meeting. As of November 14, 2014, there were 64,504,106 shares
of our common stock outstanding and entitled to vote at the meeting. With respect to “routine” matters, such as the
ratification of the selection of our independent registered public accounting firm, a bank, brokerage firm, or other nominee has
the authority (but is not required) under the rules governing self-regulatory organizations, or SRO rules, including NASDAQ, to
vote its clients’ shares if the clients do not provide instructions. When a bank, brokerage firm, or other nominee votes
its clients’ shares on routine matters without receiving voting instructions, these shares are counted both for establishing
a quorum to conduct business at the meeting and in determining the number of shares voted “for”, “against”
or “abstaining” with respect to such routine matters.
With respect to “non-routine”
matters, such as the election of directors, a bank, brokerage firm, or other nominee is not permitted under the SRO rules to vote
its clients’ shares if the clients do not provide instructions. The bank, brokerage firm, or other nominee will so note
on the voting instruction form and this constitutes a “broker non-vote.” “Broker non-votes” will be counted
for purposes of establishing a quorum to conduct business at the meeting, but not for determining the number of shares voted “for”,
“against”, “abstaining” or “withheld from” with respect to such non-routine matters.
Proposal 1: Election of Robert A. Farmer
and Jerry Jasinowski as the Class II Directors
Under our bylaws, the election of directors
requires the affirmative vote of a plurality of the votes cast, and votes may be cast in favor of the nominee or withheld. A “plurality”
means that the nominee receiving the most votes for election to a director position is elected to that position. You may withhold
votes from a nominee by notation on your proxy card. In accordance with Delaware law, abstentions and broker non-votes will be
counted for purposes of determining the presence or absence of a quorum. Abstentions and broker non-votes will not be counted for
purposes of determining the number of shares voted in the election and, accordingly, will not affect the election of directors.
Proposal 2: Advisory Votes on 2013 Executive
Compensation
The approval, on an advisory basis, of
the compensation of our Named Executive Officers (as defined below) as disclosed in this proxy statement requires the affirmative
vote of the holders of a majority of the shares of our common stock present or represented and entitled to vote on the proposal.
Abstentions and broker non-votes are not treated as votes cast, and therefore will have no effect on the proposal. Because your
vote is advisory, it will not be binding on our Board or our Company. However, the Board and the Compensation Committee will consider
the outcome of the vote when making future compensation decisions for our Named Executive Officers.
Proposal 3: Frequency of Advisory Votes
for to Approve Executive Compensation
The frequency of the advisory
vote on executive compensation receiving the greatest number of votes cast—one year, two years or three years—will
be deemed by us as the frequency that has been recommended by stockholders. Abstentions and broker non-votes are not treated as
votes cast, and therefore will have no effect on the proposal. Because your vote is advisory, it will not be binding on our Board
or our Company. However, the Board and the Compensation Committee will consider the outcome of the vote when making future decisions
regarding the frequency of the advisory vote on executive compensation.
Proposal 4: Ratification of the appointment of Marcum
LLP as our registered public accounting firm for the fiscal year ending December 31, 2014
The affirmative vote of a majority of the
votes cast at the meeting is required to ratify the appointment of Marcum LLP as our registered public accounting firm for the
fiscal year ending December 31, 2014. You may vote “for” or “against” the ratification of the appointment
of Marcum LLP as our registered public accounting firm for fiscal year ending December 31, 2014 or you may “abstain”
from voting. In accordance with Delaware law, abstentions and broker non-votes will be counted for purposes of determining the
presence or absence of a quorum. Abstentions will not be counted for purposes of determining the number of shares voted on the
matter and, accordingly, will not affect ratification of Marcum.
Householding
Stockholders of record who reside at the
same address will receive a single copy of our annual report, proxy statement and notice of annual meeting. Each stockholder in
the household, however, will receive a separate proxy card. This process, known as “householding,” reduces the volume
of duplicate information received at your household and helps to reduce our expenses. If you would like to receive a separate
copy of any of these materials, please call or write us at the address set forth under “Communication with the Board
of Directors” below, and we will promptly deliver the requested materials to you.
If you receive multiple copies of our annual
report, proxy statement and notice of annual meeting and wish to receive a single copy in the future, please contact us at the
address set forth under “Communication with the Board of Directors” below. If you hold your shares in street
name, you should contact your broker or nominee regarding combining mailings.
PROPOSAL NO. 1 —
ELECTION OF DIRECTORS
Directors and Nominee for Director
We have a classified Board currently consisting
of one Class I director (Dr. Alton L. Boynton), two Class II directors (Robert A. Farmer and Jerry Jasinowski), and
two Class III directors (Linda F. Powers and Dr. Navid Malik). At each annual meeting of stockholders, directors are elected
for a full term of three years to succeed those whose terms are expiring. This year, two Class II directors will be presented
to the stockholders for election to a three-year term that expires at the 2017 annual meeting and until their successors are elected
and qualified. The Class I director has a term that expires at the 2016 annual meeting and the Class III directors have
a term that expires at the 2015 annual meeting.
The persons named in the enclosed proxy
will vote to elect Robert A. Farmer and Jerry Jasinowski as the Class II directors, unless your proxy is marked otherwise.
Messrs. Farmer and Jasinowski have indicated their willingness to serve, if elected. If either should be unable to serve,
the person acting under the proxy may vote the proxy for a substitute nominee. We have no reason to believe that Messrs. Farmer
and Jasinowski will be unable to serve if elected.
Set forth below are the name and age of
each member of our Board (including Robert A. Farmer and Jerry Jasinowski, the nominees for election as the Class II directors),
and the positions and offices held by him or her, his or her principal occupation and business experience during at least the past
five years, the names of other publicly held companies of which he or she serves as a director and the year of the commencement
of his or her term as a member of our Board.
Vote Required
Directors are elected by a plurality of
the votes cast at the annual meeting. This means that the Class II nominees receiving the highest number of votes will be elected.
Voting by the Proxies
The proxies will
vote your common stock in accordance with your instructions. If you are a stockholder of record, unless you mark your proxy card
to withhold authority to vote, your common stock will be voted for the election of the nominee named in this proxy statement.
If you are a beneficial
owner of shares held in street name and you do not provide your broker with voting instructions, under the SRO rules governing
brokers, your broker may not vote your shares on the election of directors.
Recommendation
We recommend that you vote FOR Robert
A. Farmer and Jerry Jasinowski as the Class II directors.
Family Relationships
There are no family relationships between
any of our directors or executive officers.
Directors
Information with respect to the number
of shares of common stock beneficially owned by each director, directly or indirectly, as of September 30, 2014 appears below
under the heading “Security Ownership of Certain Beneficial Owners and Management.”
Name |
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Age |
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Position |
Linda F. Powers |
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59 |
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Class III Director, Chairperson, President and Chief Executive Officer |
Dr. Alton L. Boynton |
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70 |
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Class I Director, Chief Scientific Officer |
Robert A. Farmer |
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74 |
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Class II Director |
Dr. Navid Malik |
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45 |
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Class III Director |
Jerry Jasinowski |
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71 |
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Class II Director |
Director Biographies
Linda F. Powers. Ms. Powers
has served as the Chairperson of our Board of Directors since her appointment on May 17, 2007 and Chief Executive Officer
since June 8, 2011. Ms. Powers served as a managing director of Toucan Capital Fund II from 2001 to 2010, and Toucan Capital
Fund III thereafter. She also has over 15 years’ experience in corporate finance and restructurings, mergers and acquisitions,
joint ventures and intellectual property licensing. Ms. Powers is a Board member of M2GEN (an affiliate of
Moffitt
Cancer Center), the Chinese Biopharmaceutical Association, and
the Rosalind Franklin Society. She was the Chair of the Maryland Stem Cell Research Commission for the first two years of
the state’s stem cell funding program, and has served an additional four years on the Commission. Ms. Powers served
for several years on a Steering Committee of the National Academy of Sciences, evaluating government research funding, and has
been appointed to three Governors’ commissions created to determine how to build the respective states’ biotech and
other high-tech industries. For more than six years, Ms. Powers taught an annual internal course at the National Institutes
of Health for the bench scientists and technology transfer personnel on the development and commercialization of medical products. Ms. Powers
serves on the boards of six private biotechnology companies. Ms. Powers holds a B.A. from Princeton University,
where she graduated magna cum laude and Phi Beta Kappa. She also earned a J.D., magna cum laude, from Harvard Law School. We
believe Ms. Powers’ background and experience make her well qualified to serve as a Director.
Alton L. Boynton, Ph.D. Dr.
Boynton co-founded our Company, has served as our Chief Scientific Officer and a Director since our inception in 1998, was appointed
our Chief Operating Officer in August 2001, was appointed President in May 2003, and served as Chief Executive Officer from June
2007 to June 2011. Prior to founding our Company, Dr. Boynton headed the Molecular Oncology research lab at the Pacific Northwest
Research Foundation (the original foundation of Bill Hutchinson, from which the Fred Hutchinson Cancer Center was spun off). Dr.
Boynton also served as Director of the Department of Molecular Medicine of Northwest Hospital from 1995 to 2003 where he coordinated
the establishment of a program centered on carcinogenesis. Prior to joining Northwest Hospital, Dr. Boynton was Associate Director
of the Cancer Research Center of Hawaii, The University of Hawaii, where he also held the positions of Director of Molecular Oncology
of the Cancer Research Center and Professor of Genetics and Molecular Biology. Dr. Boynton received his Ph.D. in Radiation Biology
from the University of Iowa in 1972. We believe Dr. Boynton’s background and experience make him well qualified to serve
as a Director.
Robert A. Farmer was appointed to
the Board of Directors in December 2009. Mr. Farmer served as the national treasurer of four presidential campaigns, including
those for John Kerry, Bill Clinton, Michael Dukakis and John Glenn. In these roles he led fundraising of over $800 million.
He served under Ron Brown as treasurer of the Democratic National Committee, and served for eight years as treasurer of the Democratic
Governor’s Association. President Clinton appointed Mr. Farmer as the United States Consul General to Bermuda,
where he served from 1994 to 1999. Mr. Farmer also had a successful career as an entrepreneur, including building his own publishing
company, which he sold in 1983. Mr. Farmer currently serves on the boards of directors of International Data Group,
Dale Carnegie Associates, Sober Steering Sensors, LLC, Charlesbridge Publishing, and Haute Living. Mr. Farmer is a graduate
of Dartmouth College and Harvard Law School. We believe Mr. Farmer’s background and experience, as well as his service on
other boards of directors, make him well qualified to serve as a Director.
Dr. Navid Malik was appointed to
the Board of Directors in April 2012. Dr. Malik is the Head of Life Sciences Research at Cenkos Securities Plc. in the U.K., an
independent specialist institutional securities firm. From September 2011 through January 2012, Dr. Malik was the Head of
Life Sciences Research at Sanlam (Merchant Securities), a global financial services firm. Dr. Malik was Partner and Head of Life
Sciences at Matrix Investment Banking Division, Matrix Group, a financial services firm in London, from December 2008 through September
2011. Dr. Malik was a Senior Pharmaceuticals and Biotechnology Analyst at Wimmer Financial LLP from September 2008 through December
2008, and was the Senior Life Sciences Analyst at Collins Stewart Plc from January 2005 through September 2008. In 2011, Dr. Malik
was awarded two Starmine Awards (awarded each year by Thomson Reuters and the Financial Times): Number One Stock Picker in the
European Pharmaceutical Sector, and Number Two Stock Picker in the U.K. and Ireland Healthcare Sector. Dr. Malik holds a Ph.D.
in Drug Delivery within Pharmaceutical Sciences, as well as degrees in Biomedical Sciences Research (M.Sc.) and Biochemistry and
Physiology (B.Sc., joint honors). Dr. Malik also holds an MBA in finance from the City University Business School, London.
We believe that Dr. Malik’s extensive experience in the life sciences fields and investment banking sector make him well
qualified to serve as a Director.
Jerry Jasinowski was appointed to
the Board of Directors in April 2012. Mr. Jasinowski retired in 2007. Mr. Jasinowski currently serves on the Boards of Procurian
and the Washington Tennis and Education Foundation and has held directorships in several other companies since 1990. From 2004
through 2007, Mr. Jasinowski served as the President of the Manufacturing Institute, an organization dedicated to improving and
expanding manufacturing in the United States, of which he was a founder. Mr. Jasinowski was also the President and CEO of the National
Association of Manufacturers, a trade association with 13,000 corporate members from 1990 to 2004. Mr. Jasinowski holds an A.B.
in Economics from Indiana University and an M.A. in Economics from Columbia University. We believe that Mr. Jasinowski’s
extensive experience across a wide range of manufacturing, technology, and financial firms, including Fortune 1000 and Fortune
500 companies, make him well qualified to serve as a Director.
PROPOSAL NO. 2—ADVISORY
VOTE ON EXECUTIVE COMPENSATION
As required under the Dodd-Frank Wall Street
Reform and Consumer Protection Act of 2010, or Dodd-Frank Act, the Board of Directors is submitting a “say on pay”
proposal for stockholder consideration. While the vote on executive compensation is nonbinding and solely advisory in nature, the
Board and the Compensation Committee value the opinion of our stockholders and will review and consider the voting results.
Our executive officers are compensated based
on performance, and in a manner consistent with our strategy, competitive practice, sound corporate governance principles, and
Company and stockholder interests. We believe our compensation program is strongly aligned with the long-term interests of the
Company and our stockholders. Compensation of our executive officers is designed to enable us to attract and retain talented and
experienced senior executives to lead our Company successfully in a competitive environment.
The compensation of the Named Executive
Officers is described on pages 14-16 of this proxy statement.
We are asking stockholders to vote on the
following resolution:
“RESOLVED, that the stockholders of
Northwest Biotherapeutics, Inc. approve, on an advisory basis, the compensation paid to the Named Executive Officers as disclosed
pursuant to Item 402 of Regulation S-K, including the Summary Compensation Table for fiscal 2013, and the other related tables
and disclosures.”
As indicated above, the stockholder vote
on this resolution will not be binding on our Company or the Board of Directors, and will not be construed as overruling or determining
any decision by us or by the Board. The vote will not be construed to create or imply any change to our fiduciary duties or those
of the Board, or to create or imply any additional fiduciary duties for our Company or the Board.
Vote Required
The affirmative vote of the holders of a
majority of the shares of our common stock present or represented and entitled to vote at the meeting is required to approve the
compensation of our Named Executive Officers, as disclosed in this proxy statement.
Recommendation
The Board of Directors unanimously recommends
stockholders vote, on an advisory basis, FOR the Company’s 2013 executive compensation.
PROPOSAL NO. 3—ADVISORY
VOTE REGARDING THE FREQUENCY OF
FUTURE ADVISORY VOTES ON EXECUTIVE COMPENSATION
Under the Dodd-Frank Act, we are also required
to seek a nonbinding advisory stockholder vote regarding the frequency of submission to stockholders of a “say on pay”
advisory vote such as Proposal Two. The Dodd-Frank Act specifies that stockholders be given the opportunity to vote on our executive
compensation programs either annually, every two years, or every three years. Although this vote is advisory and nonbinding, the
Board of Directors will review voting results and give consideration to the outcome of such voting.
Our Company is a clinical stage company
involved in multiple clinical trials, which involve multi-year activities. Accordingly, as indicated below, the Board recommends
that you vote in favor of an advisory vote on our compensation program every three years.
Stockholders may cast their vote on their
preferred voting frequency by choosing the option of one year, two years, three years, or abstain from voting when voting in response
to the resolution set forth below:
“RESOLVED, that the option of once every
one year, two years, or three years that receives the highest number of votes cast for this resolution will be determined to be
the preferred frequency with which Northwest Biotherapeutics, Inc. is to hold a stockholder vote to approve the compensation of
the Named Executive Officers, as disclosed pursuant to the compensation disclosure rules of the Securities and Exchange Commission
(which disclosure shall include the Summary Compensation Table for fiscal 2013, and the other related tables and disclosures).”
As indicated above, the stockholder vote
on the frequency of nonbinding stockholder votes to approve executive compensation will not be binding on our Company or the Board
of Directors, and will not be construed as overruling or determining any decision by us or the Board. The vote will not be construed
to create or imply any change to our Company’s fiduciary duties or those of the Board, or to create or imply any additional
fiduciary duties for our Company or the Board.
Vote Required
The frequency—every one, two or three
years—receiving the greatest number of votes cast shall be deemed the recommendation of the stockholders for the frequency
of future advisory votes on executive compensation.
Recommendation
The Board unanimously recommends that stockholders
vote FOR the option of every THREE yearS as the frequency with which stockholders
are provided an advisory vote on executive compensation, as disclosed pursuant to the compensation disclosure rules of the SEC.
PROPOSAL NO. 4—RATIFICATION
OF APPOINTMENT OF INDEPENDENT
REGISTERED PUBLIC ACCOUNTING FIRM
Pursuant to its charter, the Audit Committee
of our Board has appointed the firm Marcum LLP, or Marcum, to serve as our independent registered public accounting firm for the
fiscal year ending December 31, 2014. Peterson Sullivan, PLLC, or Peterson Sullivan, served as our independent registered
public accounting firm for the fiscal year ended December 31, 2012. While the Audit Committee is solely responsible for the appointment,
compensation, retention and oversight of the independent registered public accounting firm, the Committee and the Board are requesting
that the stockholders ratify this appointment. If the stockholders ratify this appointment, the Audit Committee, in its discretion,
may appoint a different independent registered public accounting firm at any time if it believes that doing so would be in the
best interests of our Company. If the stockholders do not ratify this appointment, the Audit Committee may reconsider, but might
not change, its appointment. If the stockholders do ratify this appointment, the Audit Committee may nevertheless decide to change
our accounting firm.
On July 25, 2013, we changed our independent
registered public accounting firm from Peterson Sullivan to Marcum for the year ending December 31, 2013. The change was approved
by the Audit Committee and was made to provide us with an auditing firm with a broader national presence. Peterson Sullivan is
located in Seattle, Washington, and had served as our independent registered public accounting firm since February 16, 2005.
Peterson Sullivan’s reports
on our consolidated financial statements as of December 31, 2011 and 2012, and for the two years then ended and for the period
from March 18, 1996 (inception) to December 31, 2012 did not contain an adverse opinion or a disclaimer of opinion, although the
report contained an explanatory paragraph relating to our ability to continue as a going concern, and was not qualified or modified
as to uncertainty, audit scope or accounting principles.
During the two years ended December
31, 2012 and through July 25, 2013, there were no: (a) disagreements with Peterson Sullivan on any matter of accounting principles
or practices, financial statement disclosure, or auditing scope or procedure, which disagreements, if not resolved to Peterson
Sullivan’s satisfaction, would have caused Peterson Sullivan to make reference to the subject matter thereof in connection
with its reports on our financial statements as of December 31, 2011 and 2012, and for the two years then ended and for the period
from March 18, 1996 (inception) to December 31, 2012; or (b) “reportable events”, as defined under Item 304(a)(1)(v)
of Regulation S-K. However, Peterson Sullivan identified material weaknesses in our financial reporting process with respect to
segregation of duties and lack of controls over reporting of material transactions and developments in the financial statements.
Peterson Sullivan has indicated
to us that it concurs with the foregoing statements contained in the paragraphs above as they relate to Peterson Sullivan and furnished
a letter dated July 30, 2013 to the SEC to this effect. A copy of the letter from Peterson Sullivan is attached as Exhibit 16.1
to our current report on Form 8-K filed with the SEC on July 31, 2013.
During the two years ended December
31, 2012 and through July 25, 2013, neither we nor anyone acting on our behalf consulted with Marcum regarding any of the matters
or events set forth in Item 304(a)(2)(i) or (ii) of Regulation S-K.
Representatives of Marcum are not expected
to be present at the annual meeting of stockholders and consequently will not have the opportunity to make a statement or be available
to respond to questions.
Vote Required
Ratification of the appointment of Marcum
as our independent registered public accounting firm requires the affirmative vote of a majority of the votes cast at the meeting.
Voting by the Proxies
The proxies will vote your common stock
in accordance with your instructions. Unless you give specific instructions to the contrary, your common stock will be voted for
the ratification of the appointment of Marcum as our independent registered public accounting firm for the fiscal year ending December 31,
2014.
Recommendation
The Board unanimously recommends that you
vote FOR the ratification of the appointment of Marcum as our independent registered public accounting firm for the fiscal
year ending December 31, 2014.
SECURITY OWNERSHIP OF CERTAIN BENEFICIAL
OWNERS AND MANAGEMENT
The following table presents information
regarding the beneficial ownership of our common stock as of September 30, 2014 by:
| • | each person, or group of affiliated persons, who is known
by us to own beneficially 5% or more of any class of our equity securities; |
| • | our directors and nominees for director; |
| • | each of our named executive officers, as defined in Item 402(a)(3)
of Regulation S-K; and |
| • | our directors and executive officers as a group. |
Shares of common stock beneficially owned
and the respective percentages of beneficial ownership of common stock assumes the exercise of all options, warrants and other
securities convertible into common stock beneficially owned by such person or entity currently exercisable or exercisable within
60 days of September 30, 2014. Shares issuable pursuant to the exercise of stock options and warrants exercisable within 60 days
are deemed outstanding and held by the holder of such options or warrants for computing the percentage of outstanding common stock
beneficially owned by such person, but are not deemed outstanding for computing the percentage of outstanding common stock beneficially
owned by any other person.
Except as indicated by the footnotes below,
we believe, based on the information furnished to us, that the persons and the entities named in the table have sole voting and
investment power with respect to all shares of common stock that they beneficially own, subject to applicable community property
laws, if any. The table below is based upon the information supplied by our executive officers, directors and principal stockholders
and from Schedules 13D and 13G filed with the SEC.
Except as otherwise noted, the address
of the individuals in the following table is c/o Northwest Biotherapeutics, Inc., 4800 Montgomery Lane, Suite 800, Bethesda, MD
20814.
Name of Beneficial Owner | |
Number of Shares Beneficially Owned | | |
Percentage(1) | |
Officers and Directors | |
| | | |
| | |
Alton L. Boynton, Ph.D.(2) | |
| 195,608 | | |
| * | % |
Marnix L. Bosch, Ph.D., M.B.A.(3) | |
| 151,658 | | |
| * | % |
Linda F. Powers(4) | |
| 39,202,623 | | |
| 50.67 | % |
Robert A. Farmer(5) | |
| 174,139 | | |
| * | % |
Leslie Goldman(6) | |
| 504,501 | | |
| * | % |
Dr. Navid Malik | |
| 10,000 | | |
| * | % |
Anthony Maida, Ph.D.(7) | |
| 7,500 | | |
| * | % |
Jerry Jasinowski(8) | |
| 134,573 | | |
| * | % |
All executive officer s and directors as a group (8 persons) | |
| 40,382,602 | | |
| 51.69 | % |
5% Security Holders | |
| | | |
| | |
| |
| | | |
| | |
Toucan Partners, LLC(9) 4800 Montgomery Lane, Suite 801 Bethesda, MD 20814 | |
| 4,105,474 | | |
| 6.40 | % |
| |
| | | |
| | |
Cognate BioServices, Inc.(10) 4800 East Shelby Drive, Suite 108, Memphis, TN | |
| 29,899,143 | | |
| 41.15 | % |
| |
| | | |
| | |
Dennis Mehiel(11) 7 Renaissance Square 5th Floor White Plains, NY 10601 | |
| 4,150,843 | | |
| 6.52 | % |
| (1) | Percentage represents beneficial ownership percentage of common stock calculated in accordance with SEC rules and does not
equate to voting percentages. Based upon 62,218,685 shares of common stock issued and outstanding as of September 30, 2014. |
| (2) | Consists of (i) 12,189 shares held by Dr. Boynton and (ii) 185,419 shares of common stock underlying options that are currently
exercisable. |
| (3) | Consists of (i) 9,802 shares held by Dr. Bosch and (ii) 141,856 shares of common stock underlying options that are currently
exercisable. |
| (4) | Consists of (i) 1,572,200 shares held by Ms. Powers; (ii) 592,500 shares of common stock underlying currently exercisable options
and 1,335,659 shares of common stock underlying currently exercisable warrants held by Ms. Powers; (iii) 804,145 shares of common
stock held by Toucan Capital Fund III, L.P.; (iv) 893,502 shares of common stock underlying currently exercisable warrants held
by Toucan Capital; (v) 2,211,784 shares of common stock held by Toucan Partners, LLC; (vi) 1,893,690 shares of common stock underlying
currently exercisable warrants held by Toucan Partners; (vii) 10,432,387 shares of common stock underlying warrants held by Cognate
Bioservices, Inc.; and (viii) 19,466,756 shares of common stock held by Cognate Bioservices, Inc. Ms. Powers has voting and dispositive
power over the securities owned by the Toucan entities and Cognate Bioservices, Inc. |
| (5) | Consists of (i) 135,417 shares held by Mr. Farmer and (ii) 38,722 shares of common stock underlying currently exercisable warrants. |
| (6) | Consists of (i) 172,742 held by Mr. Goldman, (ii) 238,008 shares of common stock underlying currently exercisable warrants,
and (iii) 93,750 shares of common stock underlying currently exercisable options. |
| (7) | Consists of shares of common stock underlying currently exercisable options. |
| (8) | Consists of (i) 79,317 shares held by Mr. Jasinowski and (ii) 55,256 shares of common stock underlying currently exercisable
warrants. |
| (9) | Consists of (i) 1,893,690 shares of common stock underlying currently exercisable warrants and (ii) 2,211,784 shares of common
stock. Linda Powers holds the voting and dispositive power over the shares held by Toucan Partners, LLC. |
| (10) | Consists of (i) 19,466,756 shares of common stock and (ii) 10,432,387 shares of common stock underlying currently exercisable
warrants. Linda Powers holds the voting and dispositive power over the shares held by Cognate BioServices, Inc. |
| (11) | Includes 2,737,421 shares of common stock and warrants to acquire 1,413,422 shares of common stock. |
CORPORATE GOVERNANCE MATTERS
Board Leadership Structure
The Board believes that Ms. Powers’
service as both Chairperson of the Board and Chief Executive Officer is in our Company’s best interest and our stockholders’
best interests. Ms. Powers possesses detailed and in-depth knowledge of the issues, opportunities, and challenges facing us, and
is thus best positioned to develop Company strategies, business plans and priorities, and corresponding Board agendas that ensure
that the Board’s time and attention are focused on the most critical matters. The Company has multiple major programs under
way, with operations and infrastructure on two continents, which is unusual for a small biotech company and requires heightened
efficiency and involvement between the Board and management. Ms. Powers’ combined role enables decisive leadership, and,
we believe, facilitates this efficiency and involvement. The Board has not appointed a lead independent director.
Board of Directors’ Role in Risk Oversight
The Board plays an active role in risk
oversight of our Company. The Board does not have a formal risk management committee, but administers this oversight function through
various standing committees of the Board of Directors. The Audit Committee maintains responsibility for oversight of financial
reporting-related risks, including those related to our accounting, auditing and financial reporting practices. The Audit Committee
also reviews reports and considers any material allegations regarding potential violations of our Company’s Code of Ethics.
The Compensation Committee oversees risks arising from our compensation policies and programs. This Committee has responsibility
for evaluating and approving our executive compensation and benefit plans, policies and programs.
Director Independence
Our Board of Directors has undertaken a
review of the independence of our directors and has determined that a majority of the Board consists of members who are currently
“independent” as that term is defined within the meaning of Section 5605(a)(2) of the NASDAQ Marketplace Rules. The
Board of Directors considers Messrs. Farmer, Malik and Jasinowski to be independent.
Audit Committee
The Audit Committee has responsibility
for recommending the appointment of our independent accountants, supervising our finance function (which includes, among other
matters, our investment activities), reviewing our internal accounting control policies and procedures, and providing the Board
such additional information and materials as it may deem necessary to make the Board aware of significant financial matters which
require the attention of the Board. The Audit Committee acts under a written charter.
The Audit Committee currently consists
of Messrs. Farmer, Malik and Jasinowski. Our Board has undertaken a review of the independence of our directors and has determined
that Messrs. Farmer, Malik and Jasinowski are independent within the meaning of Section 5605(a)(2) of the NASDAQ Marketplace Rules
as well as pursuant to the additional test for independence for audit committee members imposed by SEC regulation and Section 5605(c)(2)(A)
of the NASDAQ Marketplace Rules. The Audit Committee is established in accordance with Section 3(a)(58)(A) of the Exchange Act.
Compensation Committee
The Compensation Committee is responsible
for determining the overall compensation levels of our executive officers and administering our stock option plans. Ms. Powers,
our Chairperson, President and Chief Executive Officer, participated in discussions regarding salaries and incentive compensation
for all of our executive officers, except that she was and is excluded from discussions regarding her own salary and incentive
compensation. The Board has adopted a written charter for the Compensation Committee and its current members are Messrs. Farmer,
Malik and Jasinowski. The Compensation Committee does not delegate its authority pursuant to its written charter. Our Board of
Directors has determined that all of the members are “independent” under the current listing standards of NASDAQ.
Nominations Committee
The Nominations Committee has responsibility
for assisting the Board of Directors in, among other things, effecting Board organization, membership and function, including:
identifying qualified Board nominees; effecting the organization, membership and function of Board committees, including composition
and recommendation of qualified candidates; establishment of and subsequent periodic evaluation of successor planning for the chief
executive officer and other executive officers; development and evaluation of criteria for Board membership such as overall qualifications,
term limits, age limits and independence; and oversight of compliance with the Corporate Governance Guidelines. The Nominations
Committee shall identify and evaluate the qualifications of all candidates for nomination for election as directors. Potential
nominees are identified by the Board of Directors based on the criteria, skills and qualifications that have been recognized by
the Nominations Committee. While our nomination policy does not prescribe specific diversity standards, the Nominations Committee
and its independent members seek to identify nominees that have a variety of perspectives, professional experience, education,
difference in viewpoints and skills, and personal qualities that will result in a well-rounded Board of Directors.
The Nominations Committee currently consists
of Messrs. Farmer, Malik and Jasinowski. The Board of Directors has determined that all of the members are “independent”
under the current listing standards of NASDAQ. The Board of Directors has adopted a written charter setting forth the authority
and responsibilities of the Nominations Committee.
Information Regarding Meetings of the Board and Committees
The business of our Company is under the
general oversight of our Board, as provided by the laws of Delaware and our bylaws. During the fiscal year ended December 31,
2013, the Board held no less than 15 meetings and also conducted business by written consent, the Audit Committee held 4 meetings,
the Compensation Committee held four meetings and the Nominations Committee held one meeting. Each person who was a director during
2013 attended at least 75% of the Board meetings and the meetings of the committee on which he or she served. We do not have a
formal written policy with respect to Board members’ attendance at our annual meeting of stockholders. Two of our directors
attended the 2013 annual meeting.
Code of Business Conduct and Ethics
We have adopted a formal Code of Business
Conduct and Ethics applicable to all Board members, executive officers and employees. A copy of our Code of Business Conduct and
Ethics will be provided free of charge upon request to Secretary, Northwest Biotherapeutics, Inc., 4800 Montgomery Lane, Suite
800, Bethesda, Maryland, 20814.
Nomination of Directors
The Nominations Committee is responsible
for annually reviewing with the Board the requisite skills and criteria for prospective directors and the structure, size and
composition of the Board as a whole. Although there are no set criteria considered by the Nominations Committee in evaluating
potential director nominees, the committee does consider the skills and expertise that need to be represented on the Board, succession
planning and the time commitments required of directors.
For a stockholder to submit a candidate
for the consideration of the Nominations Committee, the stockholder must timely notify our corporate secretary at the address
set forth under “Communication with the Board of Directors” below. To make such a nomination in advance of
the next year’s annual meeting, a stockholder must provide written notification to our secretary not less than 120 days
nor more than 150 days in advance of the first anniversary of the date on which the proxy statement in connection with the
previous year’s annual meeting was first mailed. However, if we do not hold an annual meeting or the date of such annual
meeting has been changed by more than 30 days from the date first contemplated by the previous year’s proxy statement,
we must receive the stockholder’s notice at least 80 days prior to the date on which we distribute the proxy statement
with respect to the upcoming meeting.
The notice must include the information
specified in our bylaws, including the following: (a) as to each proposed nominee (i) such person’s exact name,
(ii) such person’s age, principal occupation, business address and telephone number, and residence address and telephone
number, (iii) the number of shares (if any) of each class of our capital stock owned directly or indirectly by each such nominee,
and (iv) any other information concerning the nominee that must be disclosed as to nominees in proxy solicitations pursuant
to Regulation 14A under the Securities Exchange Act of 1934, as amended, or the Exchange Act, (including such person’s
notarized written acceptance of such nomination, consent to being named in the proxy statement as a nominee and statement of intention
to serve as a director if elected); and (b) as to the stockholder giving the notice (i) the name and address, as they
appear in our records, of such stockholder; (ii) such stockholder’s principal occupation, business address and telephone
number, and residence address and telephone number, (iii) the class and number of our shares which are held of record or beneficially
owned by such stockholder; and (iv) the dates upon which such stockholder acquired such shares of stock and documentary support
for any claims of beneficial ownership. In addition, notices must include a description of all arrangements or understandings between
the stockholder giving the notice and each nominee and any other person or persons (naming such person or persons) pursuant to
which the nomination or nomination are to be made by such stockholder.
Communication with the Board of Directors
We have established a procedure by which
our stockholders may communicate directly with our Board. All communications should be in written form and directed to our corporate
secretary at the following address: Northwest Biotherapeutics, Inc., 4800 Montgomery Lane, Suite 800, Bethesda, Maryland 20814,
Attention: Secretary (240) 497-9024.
EXECUTIVE OFFICERS
The following table sets forth information
regarding the Company’s current executive officers.
Name |
|
Age |
|
Position |
Linda F. Powers |
|
58 |
|
Class III Director, Chairperson, President and Chief Executive Officer |
Alton L. Boynton, Ph.D. |
|
70 |
|
Class I Director, Chief Scientific Officer |
Anthony E. Maida, Ph.D. |
|
61 |
|
Senior Vice President, Clinical Research |
Leslie J. Goldman |
|
69 |
|
Senior Vice President, Business Development |
Marnix L. Bosch, Ph.D. |
|
54 |
|
Chief Technical Officer |
Linda F. Powers. Please see “Director
Biographies” above.
Alton L. Boynton, Ph.D. Please see
“Director Biographies” above.
Anthony E. Maida, Ph.D. Dr. Maida
joined our Company in June 2011, as Chief Operating Officer. He became Senior Vice President, Clinical Research in 2014. Dr. Maida
has more than 20 years’ experience in building oncology companies, with expertise in the business, financial, clinical and
regulatory aspects of and the underlying science of oncology business. Over these two decades, Dr. Maida has held positions
as Chairman, CEO, COO, CSO, CFO and VP Business Development. Among these experiences, he served as CEO of CancerVax Corporation,
an early leader in cancer vaccines. In that role, he was responsible for conducting multi-hundred patient, multi-center clinical
trials with the company’s cancer vaccines. Prior to joining us, Dr. Maida was serving as global head of oncology for a leading
contract research organization that manages clinical trials in the U.S. and internationally.
Leslie J. Goldman joined us as Senior
Vice President, Business Development in June 2011. Prior to joining us, Mr. Goldman was a
partner at the law firm of Skadden, Arps for over 30 years,
specializing in a wide array of advanced technologies and their commercialization. Mr. Goldman also serves as an advisor
to a number of other technology companies. In addition, for eight years, Mr. Goldman served as Chairman of the Board of a group
of TV stations in four mid-size cities across the country.
Marnix L. Bosch joined us in 2000,
and has been serving as our Chief Technical Officer for a number of years. In this capacity, he plays a key role in the preparation
and submission of our regulatory applications, as well as ongoing development of our product lines, and ongoing development and/or
acquisition of new technologies. Dr. Bosch led the process of designing the protocols, and managed the successful preparation
and submission of our Investigational New Drug (IND) applications for FDA approval to conduct clinical trials for prostate cancer,
brain cancer, ovarian cancer and multiple other cancers. He also led the processes for other regulatory submissions in both
the U.S. and abroad (including the successful applications for orphan drug status in both the U.S. and Europe for DCVax-L for brain
cancer). He spearheaded the development of our manufacturing and quality control processes, and is working with Cognate BioServices,
Inc. on next-generation further development of these processes. Prior to joining us in 2000, Dr. Bosch worked at the Dutch
National Institutes of Health (RIVM) as head of the Department of Molecular Biology, as well as in academia as a professor of Pathobiology.
He has authored more than 40 peer-reviewed research publications in immunology and virology, and is an inventor on several patent
applications on dendritic cell product manufacturing.
EXECUTIVE COMPENSATION
Summary Compensation Table
The following table sets forth certain
information concerning compensation paid or accrued to our executive officers, referred to as our Named Executive Officers, during
the years ended December 31, 2013 and 2012.
Name and Principal
Position | |
Year | | |
Salary | | |
Bonus | | |
Option Awards | | |
Total | |
Linda F. Powers | |
| 2013 | | |
$ | 360,000 | | |
$ | - | | |
$ | - | | |
$ | 360,000 | |
Chairperson, President | |
| 2012 | | |
$ | 360,000 | | |
$ | - | | |
$ | - | | |
$ | 360,000 | |
& Chief Executive Officer | |
| | | |
| | | |
| | | |
| | | |
| | |
| |
| | | |
| | | |
| | | |
| | | |
| | |
Alton L. Boynton, Ph.D. | |
| 2013 | | |
$ | 295,685 | | |
$ | - | | |
$ | - | | |
$ | 295,685 | |
Chief Scientific Officer and | |
| 2012 | | |
$ | 295,685 | | |
$ | - | | |
$ | - | | |
$ | 295,685 | |
Secretary | |
| | | |
| | | |
| | | |
| | | |
| | |
| |
| | | |
| | | |
| | | |
| | | |
| | |
Anthony Maida, Ph.D. | |
| 2013 | | |
$ | 300,000 | | |
$ | - | | |
$ | - | | |
$ | 300,000 | |
Chief Operating Officer | |
| 2012 | | |
$ | 300,000 | | |
$ | - | | |
$ | - | | |
$ | 300,000 | |
| |
| | | |
| | | |
| | | |
| | | |
| | |
Leslie Goldman | |
| 2013 | | |
$ | 348,000 | | |
$ | - | | |
$ | - | | |
$ | 348,000 | |
Senior Vice President, | |
| 2012 | | |
$ | 348,000 | | |
$ | - | | |
$ | - | | |
$ | 348,000 | |
Business Development | |
| | | |
| | | |
| | | |
| | | |
| | |
| |
| | | |
| | | |
| | | |
| | | |
| | |
Marnix L. Bosch, Ph.D., | |
| 2013 | | |
$ | 325,181 | | |
$ | - | | |
$ | - | | |
$ | 325,181 | |
M.B.A. | |
| 2012 | | |
$ | 325,181 | | |
$ | - | | |
$ | - | | |
$ | 325,181 | |
Chief Technical Officer | |
| | | |
| | | |
| | | |
| | | |
| | |
Outstanding Equity Awards at Fiscal
Year-End
The following table
shows outstanding stock option awards classified as exercisable and un-exercisable as of December 31, 2013.
| |
Number of Securities Underlying Unexercised Options |
Name and Principal Position | |
Exercisable | | |
Un-exercisable | | |
Option Exercise Price ($) | | |
Option Expiration Date |
Linda F. Powers | |
| 592,500 | (1) | |
| 296,250 | | |
$ | 10.56 | | |
6/21/2018 |
Chairperson, President & Chief Executive | |
| | | |
| | | |
| | | |
|
| |
| | | |
| | | |
| | | |
|
Alton Boynton
Chief Scientific Officer and Secretary | |
| 93,750 | (2) | |
| 55,000 | | |
$ | 10.56 | | |
6/21/2018 |
| |
| 330 | (6) | |
| - | | |
$ | 300.00 | | |
4/18/2014 |
| |
| 126 | (6) | |
| - | | |
$ | 21.60 | | |
2/18/2016 |
| |
| 89,428 | (7) | |
| - | | |
$ | 8.80 | | |
8/20/2022 |
| |
| | | |
| | | |
| | | |
|
Anthony Maida | |
| 7,500 | (3) | |
| 72,994 | | |
$ | 10.56 | | |
6/21/2018 |
Chief Operating Officer | |
| | | |
| | | |
| | | |
|
| |
| | | |
| | | |
| | | |
|
Leslie Goldman | |
| 93,535 | (4) | |
| 46,875 | | |
$ | 10.56 | | |
6/21/2018 |
Senior Vice President, Business Development | |
| | | |
| | | |
| | | |
|
| |
| | | |
| | | |
| | | |
|
Marnix Bosch | |
| 93,846 | (5) | |
| 73,750 | | |
$ | 10.56 | | |
6/21/2018 |
Chief Technical Officer | |
| 21 | (8) | |
| - | | |
$ | 300.00 | | |
9/20/2014 |
| |
| 52 | (8) | |
| - | | |
$ | 1200.00 | | |
1/10/2015 |
| |
| 209 | (8) | |
| - | | |
$ | 21.60 | | |
2/18/2016 |
| |
| 338 | (8) | |
| - | | |
$ | 28.80 | | |
12/1/2016 |
| |
| 31,770 | (9) | |
| 21,355 | | |
$ | 11.20 | | |
6/23/2022 |
| |
| 15,625 | (10) | |
| - | | |
$ | 8.80 | | |
8/20/2022 |
(1) |
In conjunction with the employment agreement entered into between us and Ms. Powers on June 8, 2011, and in recognition of Ms. Powers’ service to our Company while serving as Chair during the preceding four years, we granted Ms. Powers an option to purchase 870,637 shares of our stock with an exercise price of $10.56 per share. One-third of the options vested on the grant date, and upon vesting became subject to a lock-up which extends to the earlier of 18 months or our reaching the primary endpoint of our GBM brain cancer clinical trial. One-third of the options vested in equal monthly portions over the term of the employment agreement. The remaining one-third will vest in portions tied to material milestones in multiple programs, if and to the extent those milestones are achieved, or may vest in the Board’s discretion. |
(2) |
In conjunction with the employment agreement entered into between us and Dr. Boynton on June 8, 2011, we issued Dr. Boynton an option to purchase 145,162 shares of our stock with an exercise price of $10.56 per share. 86,035 options vested on the grant date. 7,500 options vested in equal monthly portions over the term of the employment agreement. The remaining 51,627 options will vest in portions tied to material milestones in multiple programs, if and to the extent those milestones are achieved, or may vest in the Board’s discretion. |
(3) |
In conjunction with the employment agreement entered into between us and Dr.
Maida on May 31, 2011, we issued Dr. Maida an option to purchase 76,163 shares of our stock with an exercise price of $10.56
per share. No options vested on the grant date. 7,500 options vested in equal monthly portions over the term of the
employment agreement. The remainder will vest in portions tied to material milestones in multiple programs, if and to the
extent those milestones are achieved, or may vest in the Board’s discretion. |
(4) |
In conjunction with the employment agreement entered into between us and Mr. Goldman on June 8, 2011, we issued Mr. Goldman an option to purchase 137,750 shares of our stock with an exercise price of $10.56 per share. One-third of the options vested on the grant date, and upon vesting became subject to a lock-up which extends to the earlier of 18 months or our reaching the primary endpoint of our GBM brain cancer clinical trial. One-third vested in equal monthly portions over the term of the employment agreement. The remaining one-third will vest in portions tied to material milestones in multiple programs, if and to the extent those milestones are achieved, or may vest in the Board’s discretion. |
(5) |
In conjunction with the employment agreement entered into between us and Dr. Bosch on June 8, 2011, we issued Dr. Bosch an option to purchase 145,473 shares of our stock with an exercise price of $10.56 per share. 51,971 options vested on the grant date. 7,500 options vested in equal monthly portions over the term of the employment agreement. The remaining 51,627 options will vest in portions tied to material milestones in multiple programs, if and to the extent those milestones are achieved, or may vest in the Board’s discretion. |
(6) |
These options were granted under the 1999 Plan, the 2001 Plan and under Dr. Boynton’s previous employment agreement. Each of these option grants vests over a four year period. One-fourth of each option grant vests on the first anniversary of the grant date and the remaining three-fourths of each grant vests in equal monthly installments over the remaining three year vesting period. |
(7) |
This option was granted under the 2007 Stock Option Plan. The options were granted August 21, 2009 and vested over a one year period and are exercisable over a 10 year period from issuance at a price of $8.80 per share. |
(8) |
These options were granted under the 1999 Plan and the 2001 Plan. Each of these option grants vested over a four year period. One-fourth of each option grant vested on the first anniversary of the grant date and the remaining three-fourths of each grant vested in equal monthly installments over the remaining three year vesting period. |
(9) |
These options were granted under the 2007 Stock Option Plan. 1,250 options vested each month until May 31, 2013. In addition, 6,250 options vest upon each of Swiss Approval, full Enrollment in Phase II Glioblastoma Multiforme clinical study and FDA approval of NDA. |
(10) |
This option was granted under the 2007 Stock Option Plan. This option grant vested over the balance of 2009 with 7,813 vesting on the grant date and the remainder vesting on December 31, 2009. |
Employment Agreements
In May 2011, we entered
into employment agreements with each of Linda Powers, Dr. Alton Boynton, Leslie Goldman and Marnix Bosch. In June 2011, we entered
into an employment agreement with Dr. Anthony Maida. All of these agreements expired at the end of their respective terms in May
or June 2013.
DIRECTOR COMPENSATION
The following table sets forth certain
information concerning compensation paid or accrued to our non-executive directors during the year ended December 31, 2013.
| |
| | |
Fees Earned | | |
| | |
| |
| |
| | |
or Paid in | | |
All other | | |
| |
Name | |
Year | | |
Cash | | |
Compensation | | |
Total | |
| |
| | |
| | |
| | |
| |
Robert A. Farmer | |
| 2013 | | |
$ | 120,000 | | |
$ | - | | |
$ | 120,000 | |
Dr. Navid Malik | |
| 2013 | | |
$ | - | | |
$ | - | | |
$ | - | |
Jerry Jasinowski | |
| 2013 | | |
$ | - | | |
$ | - | | |
$ | - | |
CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS
Cognate BioServices
On July 31, 2013, Cognate BioServices,
Inc., or Cognate, agreed to convert an aggregate of $11.6 million in notes payable into shares of our common stock at a conversion
price of $4.00 per share, which resulted in the issuance of an aggregate of 2.9 million shares of common stock. The conversion
shares will be subject to a lock-up period of 18 months from the date of their issuance. Under the lock-up, the shares cannot be
sold or traded. The conversions and lock-up are subject to a most favored nation provision with respect to terms provided to other
investors.
On a going forward basis, commencing with
August 2013, we and Cognate agreed to establish a regular ongoing arrangement for payment of at least half of each invoice in shares
of our common stock, and the remainder in cash, at $4.00 per share. The conversions are subject to a most favored nation provision
with respect to terms provided to other investors. The arrangement will continue until terminated by mutual agreement.
On January 17, 2014, we entered into the
following agreements (collectively, the “Cognate Agreements” or the “Agreements”) with Cognate for manufacturing
and related services for our DCVax® products:
| · | a DCVax®-L Manufacturing and Services Agreement; |
| · | a DCVax®-Direct Manufacturing and Services Agreement; |
| · | an Ancillary Services Agreement; and |
| · | a Manufacturing Expansion Services Agreement. |
Together, these Agreements provide for
substantial expansion of manufacturing capacity for our programs, in multiple regions, as well as development of the necessary
systems and logistics, and other near-term and long-term preparations, for large scale scale-up of our programs.
The DCVax®-L Manufacturing and Services
Agreement replaces the prior manufacturing services agreement, dated April 1, 2011, between us and Cognate, and provides for manufacturing
of DCVax®-L products for various cancers, including brain cancer, and related services. In return for the services provided
by Cognate during 2013 in excess of the services that we had contracted for under the prior Services Agreement, and in return for
the completion of milestones by Cognate, and to cover the initiation of substantially expanded DCVax®-L manufacturing services
following execution of the DCVax®-L Manufacturing and Services Agreement, we made a milestone and initiation payment, comprised
of 1,020,273 shares of our common stock and a warrant to purchase 486,802 shares of our common stock. The warrants are exercisable
at $4.00 per share, and have an exercise period of five years from issuance.
The DCVax®-Direct Manufacturing and
Services Agreement provides for these services to continue and to expand substantially along with expansion of our DCVax®-Direct
program. In return for the services provided by Cognate during 2013, and the completion of milestones by Cognate, and to cover
the initiation of substantially expanded DCVax®-Direct manufacturing services following execution of the DCVax®-Direct
Manufacturing and Services Agreement, we made a milestone and initiation payment. Such payment comprised of 1,683,451 shares of
our common stock and a warrant to purchase 803,224 shares of our common stock. The warrants are exercisable at $4.00 per share,
and have an exercise period of five years from issuance.
The Ancillary Services Agreement
provides for other categories of services that will be needed on an expanded scale for clinical programs, compassionate use and
other early access or expanded access programs, and eventual commercialization. In return for the services provided by Cognate
during 2013, and the completion of milestones by Cognate, and to cover the initiation of a broad scope of Ancillary Services on
an accelerated basis, we made a milestone and initiation payment comprised of 1,326,355 shares of our common stock and a warrant
to purchase 632,843 shares of our common stock. The warrants are exercisable at $4.00 per share, and have an exercise period of
five years from issuance and a cashless exercise provision.
The Manufacturing Expansion Services
Agreement covers services associated with designing and developing new or expanded manufacturing capacity or facilities dedicated
to the Company’s DCVax products, preparing the regulatory submissions, and obtaining and maintaining applicable certifications.
In return for the services provided by Cognate during 2013, and to cover the initiation of a broad scope of Manufacturing Expansion
Services on an accelerated basis, we made a Milestone and Initiation Payment comprised of 1,071,287 shares of our common stock
and a warrant to purchase 511,142 shares of our common stock. The warrants are exercisable at $4.00 per share, and have an exercise
period of five years from issuance and a cashless exercise provision.
We also entered into a Lock-Up Agreement
with Cognate on January 17, 2014, under which Cognate agreed to have all of the shares that are issued as part of the Milestone
and Initiation Payments in the Cognate Agreements (collectively, the “Lock-Up Shares”) locked up for up to 36 months,
in return for 15% warrant coverage for each 6-month period of lock-up, on the same terms as the warrants in the Cognate Agreements.
During the lock-up, the Lock-Up Shares may not be sold or traded on the market. These lock-up terms are subject to the same most
favored nation treatment as provided in the Cognate Agreements as described above. We
also agreed to extend the exercise period of all current and
past warrants held by or on behalf of Cognate for three additional years from their existing expiration dates.
Beginning on July 31, 2013, pursuant to
this arrangement, we have issued to Cognate an aggregate of 8,907,750 shares and warrants to purchase an aggregate of 4,582,176
shares through September 30, 2014.
The amounts paid by us in shares and warrants
under each of the Cognate Agreements will be subject to adjustment on a most favored nation basis relative to the terms provided
by us to any other investor or creditor during the term of such Agreement, so that the terms of all securities issued or issuable
under the agreements will have terms no less favorable to Cognate than the terms of any securities issued or issuable to any other
investor or creditor during the term of the respective Agreement, including not only the price and terms of securities issued but
also additional securities, rights and/or benefits to the investor or creditor (including warrants, rights of first refusal, pre-emptive
rights, and/or other securities, rights or benefits). On November 12, 2014, the Board approved the issuance of 8,052,092 shares
of common stock to Cognate for services and most favored nation provisions in accordance with the Cognate agreements. On November
12, 2014, the Board approved the issuance of 3,812,555 warrants to Cognate for services and most favored nation provisions in accordance
with the Cognate agreements. The warrants will have a term of 5.0 years and an initial exercise
price of $4.00, and will be subject to a most favored nation provision.
In July 2013,
we received a short-term loan of $0.6 million from Cognate. The short-term loan was paid-in-full during the third quarter of 2013.
In October and November 2013, we received short-term loans of $0.6 million from Cognate. These short-term loans were paid-in-full
during December of 2013.
In March 2013, we received a short-term
loan of $0.2 million from Toucan Capital. The short-term loan was paid-in-full during the second quarter of 2013. Linda Powers,
our Chief Executive Officer and a director, is a principal of Toucan Capital, which also is a substantial stockholder.
In March 2013, we received a short-term
loan of $0.2 million from Leslie Goldman, our Senior Vice President, Business Development. The short-term loan was paid-in-full
during the second quarter of 2013.
Review, approval or ratification of transactions with related
persons
With respect to reviewing and approving
related-party transactions, the Board reviews related-party transactions for potential conflicts of interests or other improprieties.
Under SEC rules, related-party transactions are those transactions to which we are or may be a party in which the amount involved
exceeds the lesser of $120,000 or one percent of the average of our total assets at year end for the last two completed fiscal
years, and in which any of our directors or executive officers or any other related person had or will have a direct or indirect
material interest, excluding, among other things, compensation arrangements with respect to employment or board membership. Any
transactions with officers, directors or 5% stockholders are on market-based terms, and are approved by a majority of our independent
and disinterested directors.
Audit Committee Report
As part of its specific duties, the Audit
Committee reviews our Company’s financial reporting process on behalf of the Board; reviews the financial information issued
to stockholders and others, including a discussion of the quality, acceptability, and clarity of the information, and monitors
our systems of internal control and the audit process. Management is responsible for the preparation, presentation, and integrity
of our financial statements, accounting and financial reporting principles, and disclosure controls and procedures designed to
ensure compliance with accounting standards and applicable laws and regulations. Management also is responsible for objectively
reviewing and evaluating the adequacy, effectiveness, and quality of our own system of internal control. Our independent registered
public accounting firm is responsible for performing an independent audit of the consolidated financial statements and expressing
an opinion on the conformity of those financial statements with generally accepted accounting principles.
The Audit Committee
has reviewed and discussed with management our audited financial statements for the fiscal year ended December 31, 2013. The
Audit Committee has discussed with Marcum LLP, our Company’s independent registered public accounting firm for the fiscal
year ended December 31, 2013, the matters required to be discussed by the statement on Auditing Standards No. 61, as amended
(AICPA, Professional Standards, Vol. 1 AU Section 380), as adopted by the Public Company Accounting Oversight Board, or PCAOB,
in Rule 3200T. The Audit Committee has received the written disclosures and letter from Marcum LLP, our independent registered
public accounting firm required by applicable requirements of the PCAOB regarding the independent registered public accounting
firm’s communications with the Audit Committee concerning independence, and has discussed with the independent registered
public accounting firm the independent registered public accounting firm’s independence. The Audit Committee has also considered
whether the provision of services other than the audit of our financial statements were compatible with maintaining Marcum LLP’s
independence.
Based on the
review and discussions referred to in the foregoing paragraph, the Audit Committee recommended to the Board of Directors that
the audited financial statements be included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2013
for filing with the SEC.
THE AUDIT COMMITTEE
Robert A. Farmer
Jerry Jasinowski
Dr. Navid Malik
PRINCIPAL ACCOUNTANT FEES AND SERVICES
Fees Paid to Marcum LLP
Marcum LLP was engaged in 2013 and served
as our independent public accounting firm for the fiscal year ended December 31, 2013.
Audit Fees
The aggregate fees billed and unbilled
of the fiscal year ended December 31, 2013 for professional services rendered by Marcum for the audit of our annual financial
statements, the review of our financial statements included in our quarterly reports on Form 10-Q and consultations and consents
were approximately $175,000.
Audit-Related Fees
There were no fees billed in the fiscal
year ended December 31, 2013 for assurance and related services rendered by Marcum related to the performance of the audit
or review of our financial statements.
Tax and Other Fees
There were no fees billed in the fiscal
year ended December 31, 2013 for professional services rendered by Marcum for tax related services or other fees.
Policy on Audit Committee Pre-Approval of Audit and Permissible
Non-Audit Services
Consistent with SEC policies and guidelines
regarding audit independence, the Audit Committee is responsible for the pre-approval of all audit and permissible non-audit services
provided by our principal accountants on a case-by-case basis. Our Audit Committee has established a policy regarding approval
of all audit and permissible non-audit services provided by our principal accountants. Our Audit Committee pre-approves these
services by category and service. Our Audit Committee pre-approved all of the services provided by our principal accountants during
the fiscal years ended December 31, 2013 and 2012.
OTHER MATTERS
Section 16(a) Beneficial Ownership Reporting Compliance
Section 16(a) of the Exchange Act
requires our directors, executive officers and persons who own more than 10% of our stock, or Reporting Persons, to file with the
SEC initial reports of ownership and changes in ownership of our stock. Reporting Persons are required by SEC regulations to furnish
us with copies of all Section 16(a) reports they file. To our knowledge, based solely on our review of the copies of such
reports received, we believe that during our fiscal year ended December 31, 2013 all Reporting Persons timely complied with
all applicable filing requirements, except that Cognate Bioservices made non-timely filings of Form 4 reports for the issuance
to Cognate of (i) a warrant on July 31, 2013 to purchase 2,116,064 shares of common stock, (ii) 2,902,072 shares of common stock
on August 8, 2013, (iii) 233,042 shares and a warrant to purchase 111,521 shares of common stock on December 2, 2013, and (iv)
257,439 shares and a warrant to purchase 128,720 shares of common stock on December 19, 2013, all of which acquisitions were pursuant
to the conversion of accounts payable owed to Cognate, which reports have not been filed. In addition, each of Dr. Navid Malik
and Jerry Jasinowski has not filed a Form 3 in connection with their appointment to the Board of Directors.
Stockholder Proposals for the 2015 Annual Meeting of Stockholders
We have not yet determined when we will
hold the 2015 annual meeting of stockholders, but we anticipate issuing a press release announcing such date when it is determined.
Proposals of stockholders intended to be presented at the 2015 annual meeting pursuant to Rule 14a-8 under the Exchange Act
must be received by us no later than the close of business on July 29, 2015 in order that they may be included in the proxy statement
and form of proxy relating to that meeting. Proposals should be addressed to Northwest
Biotherapeutics, Inc., 4800 Montgomery Lane, Suite 800,
Bethesda, Maryland 20814, Attention: Secretary.
In addition, our bylaws require that we
be given advance notice of stockholder nominations for election to our Board and of other business that stockholders wish to present
for action at an annual meeting of stockholders (other than matters included in our proxy statement in accordance with Rule 14a-8).
Our secretary must receive such notice not less than 120 days nor more than 150 days prior to the first anniversary
of the date on which this proxy statement was first mailed to our stockholders. If the date on which the 2015 annual meeting will
be held is changed by more than 30 calendar days from the date of the 2014 annual meeting, we must receive the notice at least
80 days prior to the date on which we intend to distribute the corresponding proxy statement.
The notice for any stockholder proposal
must contain certain information set forth in our bylaws. In addition, stockholder proposals made under Rule 14a-8 under
the Exchange Act are required to contain certain information. Therefore, we strongly encourage stockholders interested in submitting
a proposal to contact legal counsel with regard to the detailed requirements of applicable securities laws. Copies of our bylaws
can be obtained without charge from our corporate secretary.
Submitting a stockholder proposal does
not guarantee that we will include it in our proxy statement.
THE BOARD HOPES THAT STOCKHOLDERS WILL
ATTEND THE MEETING IN PERSON. WHETHER OR NOT YOU PLAN TO ATTEND, YOU ARE URGED TO COMPLETE, SIGN, DATE AND RETURN THE ENCLOSED
PROXY CARD IN THE ACCOMPANYING ENVELOPE. PROMPT RESPONSES WILL GREATLY FACILITATE ARRANGEMENTS FOR THE MEETING AND YOUR COOPERATION
IS APPRECIATED. STOCKHOLDERS WHO ATTEND THE MEETING MAY VOTE THEIR STOCK PERSONALLY EVEN THOUGH THEY HAVE SENT IN THEIR PROXY
CARDS.
By Order of the Board of Directors, |
|
|
|
|
|
/s/Linda F. Powers |
|
|
Chairperson of the Board of Directors |
November 26, 2014
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