TIDMAKT 
 
RNS Number : 6872K 
Piper Jaffray Ltd 
23 April 2010 
 
                                                           FORM 8.5 (EPT/NON-RI) 
 
          PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY AN 
EXEMPT PRINCIPAL TRADER WITHOUT RECOGNISED INTERMEDIARY ("RI") STATUS (OR WHERE 
                          RI STATUS IS NOT APPLICABLE) 
                   Rule 8.5 of the Takeover Code (the "Code") 
 
1.         KEY INFORMATION 
 
+-----------------+--------------+ 
| (a)             | Piper        | 
| Name            | Jaffray      | 
| of              | Ltd.         | 
| exempt          |              | 
| principal       |              | 
| trader:         |              | 
+-----------------+--------------+ 
| (b)             | Ark          | 
| Name            | Therapeutics | 
| of              | Group plc    | 
| offeror/offeree |              | 
| in relation to  |              | 
| whose relevant  |              | 
| securities this |              | 
| form relates:   |              | 
| Use a           |              | 
| separate form   |              | 
| for each        |              | 
| offeror/offeree |              | 
+-----------------+--------------+ 
| (c)             | Ark          | 
| Name            | Therapeutics | 
| of the          | Group plc    | 
| party           |              | 
| to the          |              | 
| offer           |              | 
| with            |              | 
| which           |              | 
| exempt          |              | 
| principal       |              | 
| trader is       |              | 
| connected:      |              | 
+-----------------+--------------+ 
| (d)             | 22           | 
| Date            | April        | 
| position        | 2010         | 
| held/dealing    |              | 
| undertaken:     |              | 
+-----------------+--------------+ 
| (e)             | NO           | 
| Has             | If           | 
| the             | YES,         | 
| EPT             | specify      | 
| previously      | which:       | 
| disclosed,      |              | 
| or is it        |              | 
| today           |              | 
| disclosing,     |              | 
| under the       |              | 
| Code in         |              | 
| respect of      |              | 
| any other       |              | 
| party to        |              | 
| this offer?     |              | 
+-----------------+--------------+ 
 
2.         POSITIONS OF THE EXEMPT PRINCIPAL TRADER 
 
(a)        Interests and short positions in the relevant securities of the 
offeror or offeree to which the disclosure relates following the dealing (if 
any) 
 
+----------------+---------+--------+--------+--------+ 
| Class          |            Ordinary 1p             | 
| of             |                                    | 
| relevant       |                                    | 
| security:      |                                    | 
|                |                                    | 
+----------------+------------------------------------+ 
|                |    Interests     |Short positions  | 
|                |                  |                 | 
+                +------------------+-----------------+ 
|                | Number  |   %    |Number  |   %    | 
+----------------+---------+--------+--------+--------+ 
| (1)            |         |        |        |        | 
| Relevant       |550,884  | 0.26%  |        |        | 
| securities     |         |        |        |        | 
| owned          |         |        |        |        | 
| and/or         |         |        |        |        | 
| controlled:    |         |        |        |        | 
+----------------+---------+--------+--------+--------+ 
| (2)            |         |        |        |        | 
| Derivatives    |         |        |        |        | 
| (other than    |         |        |        |        | 
| options):      |         |        |        |        | 
+----------------+---------+--------+--------+--------+ 
| (3)            |         |        |        |        | 
| Options        |         |        |        |        | 
| and            |         |        |        |        | 
| agreements     |         |        |        |        | 
| to             |         |        |        |        | 
| purchase/sell: |         |        |        |        | 
+----------------+---------+--------+--------+--------+ 
|                |         |        |        |        | 
|                |550,884  | 0.26%  |        |        | 
| TOTAL:         |         |        |        |        | 
+----------------+---------+--------+--------+--------+ 
 
All interests and all short positions should be disclosed. 
 
Details of any open derivative or option positions, or agreements to purchase or 
sell relevant securities, should be given on a Supplemental Form 8 (Open 
Positions). 
 
(b)        Rights to subscribe for new securities (including directors' and 
other executive options) 
 
+--------------+--------+ 
| Class        |        | 
| of           |        | 
| relevant     |        | 
| security     |        | 
| in           |        | 
| relation     |        | 
| to which     |        | 
| subscription |        | 
| right        |        | 
| exists:      |        | 
+--------------+--------+ 
| Details,     |        | 
| including    |        | 
| nature of    |        | 
| the          |        | 
| rights       |        | 
| concerned    |        | 
| and          |        | 
| relevant     |        | 
| percentages: |        | 
+--------------+--------+ 
 
If there are positions or rights to subscribe to disclose in more than one class 
of relevant securities of the offeror or offeree named in 1(b), copy table 2(a) 
or (b) (as appropriate) for each additional class of relevant security. 
 
3.         DEALINGS (IF ANY) BY THE EXEMPT PRINCIPAL TRADER 
 
(a)        Purchases and sales 
 
+----------+---------------+------------+--------+ 
|  Class   |Purchase/sale  |  Number    | Price  | 
|    of    |               |    of      |  per   | 
|relevant  |               |securities  |  unit  | 
|security  |               |            |        | 
+----------+---------------+------------+--------+ 
| Ordinary | Purchase      | 1,267      | 9.75p  | 
| 1p       |               |            |        | 
+----------+---------------+------------+--------+ 
| Ordinary | Purchase      | 1,333      | 9.76p  | 
| 1p       |               |            |        | 
+----------+---------------+------------+--------+ 
| Ordinary | Purchase      | 25,000     | 10.00p | 
| 1p       |               |            |        | 
+----------+---------------+------------+--------+ 
 
(b)        Derivatives transactions (other than options) 
 
+----------+-------------+---------------------+------------+--------+ 
|  Class   |  Product    |       Nature        |  Number    | Price  | 
|    of    |description  |         of          |    of      |  per   | 
|relevant  |  e.g. CFD   |      dealing        | reference  |  unit  | 
|security  |             |        e.g.         |securities  |        | 
|          |             |  opening/closing    |            |        | 
|          |             |    a long/short     |            |        | 
|          |             |      position,      |            |        | 
|          |             |increasing/reducing  |            |        | 
|          |             |    a long/short     |            |        | 
|          |             |      position       |            |        | 
+----------+-------------+---------------------+------------+--------+ 
|          |             |                     |            |        | 
|          |             |                     |            |        | 
+----------+-------------+---------------------+------------+--------+ 
 
(c)        Options transactions in respect of existing securities 
 
(i)         Writing, selling, purchasing or varying 
 
+----------+-------------+-------------+------------+----------+-----------+--------+----------+ 
|  Class   |  Product    |  Writing,   |  Number    |Exercise  |   Type    |Expiry  |  Option  | 
|    of    |description  |purchasing,  |    of      |  price   |   e.g.    |  date  |  money   | 
|relevant  |  e.g. call  |  selling,   |securities  |per unit  |American,  |        |  paid/   | 
|security  |   option    |  varying    |  to which  |          | European  |        |received  | 
|          |             |    etc.     |  option    |          |   etc.    |        |per unit  | 
|          |             |             |  relates   |          |           |        |          | 
+----------+-------------+-------------+------------+----------+-----------+--------+----------+ 
|          |             |             |            |          |           |        |          | 
+----------+-------------+-------------+------------+----------+-----------+--------+----------+ 
 
(ii)        Exercising 
 
+----------+-------------+------------+----------+ 
|  Class   |  Product    |  Number    |Exercise  | 
|    of    |description  |    of      |  price   | 
|relevant  |  e.g. call  |securities  |per unit  | 
|security  |   option    |            |          | 
+----------+-------------+------------+----------+ 
|          |             |            |          | 
|          |             |            |          | 
+----------+-------------+------------+----------+ 
 
(d)        Other dealings (including subscribing for new securities) 
 
+----------+---------------+---------+-------------+ 
|  Class   |    Nature     |Details  |    Price    | 
|    of    |      of       |         |    per      | 
|relevant  |    dealing    |         |    unit     | 
|security  |     e.g.      |         |    (if      | 
|          |subscription,  |         |applicable)  | 
|          |  conversion   |         |             | 
+----------+---------------+---------+-------------+ 
|          |               |         |             | 
|          |               |         |             | 
+----------+---------------+---------+-------------+ 
 
The currency of all prices and other monetary amounts should be stated. 
 
Where there have been dealings in more than one class of relevant securities of 
the offeror or offeree named in 1(b), copy table 3(a), (b), (c) or (d) (as 
appropriate) for each additional class of relevant security dealt in. 
 
4.         OTHER INFORMATION 
 
(a)        Indemnity and other dealing arrangements 
 
+-----------------+ 
| Details         | 
| of any          | 
| indemnity       | 
| or option       | 
| arrangement,    | 
| or any          | 
| agreement or    | 
| understanding,  | 
| formal or       | 
| informal,       | 
| relating to     | 
| relevant        | 
| securities      | 
| which may be    | 
| an inducement   | 
| to deal or      | 
| refrain from    | 
| dealing         | 
| entered into    | 
| by the exempt   | 
| principal       | 
| trader making   | 
| the disclosure  | 
| and any party   | 
| to the offer    | 
| or any person   | 
| acting in       | 
| concert with a  | 
| party to the    | 
| offer:          | 
| If there are    | 
| no such         | 
| agreements,     | 
| arrangements    | 
| or              | 
| understandings, | 
| state "none"    | 
+-----------------+ 
|                 | 
|                 | 
|                 | 
+-----------------+ 
 
(b)        Agreements, arrangements or understandings relating to options or 
derivatives 
 
+-----------------+ 
| Details         | 
| of any          | 
| agreement,      | 
| arrangement     | 
| or              | 
| understanding,  | 
| formal or       | 
| informal,       | 
| between the     | 
| exempt          | 
| principal       | 
| trader making   | 
| the disclosure  | 
| and any other   | 
| person          | 
| relating to:    | 
| (i)  the        | 
| voting rights   | 
| of any          | 
| relevant        | 
| securities      | 
| under any       | 
| option; or      | 
| (ii) the        | 
| voting rights   | 
| or future       | 
| acquisition or  | 
| disposal of     | 
| any relevant    | 
| securities to   | 
| which any       | 
| derivative is   | 
| referenced:     | 
| If there are    | 
| no such         | 
| agreements,     | 
| arrangements    | 
| or              | 
| understandings, | 
| state "none"    | 
+-----------------+ 
|                 | 
|                 | 
|                 | 
+-----------------+ 
 
(c)        Attachments 
 
+--------------+--------+ 
| Is a         |  NO    | 
| Supplemental |        | 
| Form 8 (Open |        | 
| Positions)   |        | 
| attached?    |        | 
+--------------+--------+ 
 
 
+-------------+---------------+ 
| Date        | 23            | 
| of          | April         | 
| disclosure: | 2010          | 
+-------------+---------------+ 
| Contact     | Norman        | 
| name:       | Gould         | 
+-------------+---------------+ 
| Telephone   | 020 3142 8780 | 
| number:     |               | 
+-------------+---------------+ 
 
Public disclosures under Rule 8 of the Code must be made to a Regulatory 
Information Service and must also be emailed to the Takeover Panel at 
monitoring@disclosure.org.uk.  The Panel's Market Surveillance Unit is available 
for consultation in relation to the Code's dealing disclosure requirements on 
+44 (0)20 7638 0129. 
 
The Code can be viewed on the Panel's website at www.thetakeoverpanel.org.uk. 
 
 
This information is provided by RNS 
            The company news service from the London Stock Exchange 
   END 
 
 FEOPGUCGCUPUUBW 
 

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