Thermo Fisher Scientific Introduces the Only Fully Automated Plasmid Purification System to Help Accelerate Discovery and Development of Therapies
25 June 2024 - 10:15PM
Business Wire
Thermo Scientific™ KingFisher™ PlasmidPro
prepares high purity plasmid DNA in approximately 75 minutes, half
the traditional process time and without the need for
centrifugation
Thermo Fisher Scientific Inc., the world leader in serving
science, today introduced the Thermo Scientific™ KingFisher™
PlasmidPro Maxi Processor* (PlasmidPro), the only fully automated
maxi-scale plasmid DNA (pDNA) purification system. PlasmidPro
enables innovation at scale, providing complete automation across
mini and maxi scale purification and delivering high-purity plasmid
without manual column preparation and intervention. This is the
latest addition to the Thermo Scientific KingFisher instrument
portfolio which offers a wide range of plasmid DNA extraction
products to help drive efficiency and consistency.
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Thermo Scientific™ KingFisher™ PlasmidPro
Maxi Processor, the only fully automated maxi-scale plasmid DNA
(pDNA) purification system. (Photo: Business Wire)
Globally, there are approximately 1,700 clinical trials for cell
and gene therapies.1 In recent years, plasmids have been
instrumental in the development of cell and gene therapies,
monoclonal antibody therapies and mRNA therapies and vaccines.
Plasmids are commonly used in a variety of molecular biology
applications, including transfection, protein expression, gene
therapy, DNA sequencing, and vaccine development. They are a
critical laboratory tool that can act as a carrier to deliver
desired genes or DNA fragments into target cells.
“With the rapidly growing demand for plasmid DNA purification
for emerging therapies, we are proud to accelerate the purification
process with a ‘press and go’ solution,” said Amy Butler,
president, biosciences, Thermo Fisher Scientific. “By fully
automating a critical step in plasmid DNA manufacturing, the
PlasmidPro DNA purification system can give time back to our
customers to focus on their research and bringing life-saving
therapies and vaccines to patients.”
The PlasmidPro purification system requires no set-up,
centrifugation or pipetting and completely automates the
purification process from culture to plasmid. The product uses a
self-contained cartridge pre-filled with all necessary reagents to
perform the purification, eliminating the need for additional
instrumentation and plastics while minimizing set-up time and
contamination risks. Using 100-150 mL of fresh overnight culture,
the system is capable of producing up to 1.5 mg DNA yield.
For more information on PlasmidPro, please visit
thermofisher.com/plasmidpro.
*For research use only. Not for use in diagnostic
procedures.
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. is the world leader in serving
science, with annual revenue over $40 billion. Our Mission is to
enable our customers to make the world healthier, cleaner and
safer. Whether our customers are accelerating life sciences
research, solving complex analytical challenges, increasing
productivity in their laboratories, improving patient health
through diagnostics or the development and manufacture of
life-changing therapies, we are here to support them. Our global
team delivers an unrivaled combination of innovative technologies,
purchasing convenience and pharmaceutical services through our
industry-leading brands, including Thermo Scientific, Applied
Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services,
Patheon and PPD. For more information, please visit
www.thermofisher.com.
1
https://alliancerm.org/wp-content/uploads/2024/05/Trials_Final_Q1_2024.pdf
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Media Contact Information: Name: Kristin Blake Phone:
760-637-1166 E-mail: kristin.blake@thermofisher.com