Amended Statement of Ownership (sc 13g/a)
14 April 2016 - 12:21AM
Edgar (US Regulatory)
UNITED STATES
SECURITIES AND EXCHANGE
COMMISSION
Washington, DC 20549
SCHEDULE 13G/A
Under the Securities Exchange Act of 1934
(Amendment No. 2)*
Biotie Therapies Oyj
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(Name of Issuer)
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Common Stock
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(Title of Class of Securities)
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09074D103
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(CUSIP Number)
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April
11, 2016
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(Date of Event Which Requires Filing of this Statement)
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Check the appropriate box to designate the
rule pursuant to which this Schedule is filed:
o
Rule
13d-1(b)
x
Rule
13d-1(c)
o
Rule
13d-1(d)
*The remainder of this cover page shall be
filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for
any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.
The information required in the remainder of
this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934
(“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions
of the Act (however, see the Notes).
CUSIP No. 09074D103
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SCHEDULE 13G/A
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Page 2
of 8 Pages
|
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1
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NAME OF REPORTING
PERSONS
I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
OrbiMed Capital GP V LLC
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2
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CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
(a)
o
(b)
o
|
|
3
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SEC USE ONLY
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4
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CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
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NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
|
5
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SOLE VOTING POWER
0
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6
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SHARED VOTING POWER
0
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7
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SOLE DISPOSITIVE POWER
0
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8
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SHARED DISPOSITIVE POWER
0
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9
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AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
0
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10
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CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (See Instructions)
|
o
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11
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PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
0.00%
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12
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TYPE OF REPORTING PERSON (See Instructions)
OO
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CUSIP
No. 09074D103
|
SCHEDULE 13G/A
|
Page 3
of 8 Pages
|
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1
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NAME OF REPORTING
PERSONS
I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
OrbiMed Advisors LLC
|
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
(a)
o
(b)
o
|
|
3
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SEC USE ONLY
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4
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CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
|
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
|
5
|
SOLE VOTING POWER
0
|
6
|
SHARED VOTING POWER
0
|
7
|
SOLE DISPOSITIVE POWER
0
|
8
|
SHARED DISPOSITIVE POWER
0
|
9
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AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
0
|
10
|
CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (See Instructions)
|
o
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11
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PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
0.00%
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12
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TYPE OF REPORTING PERSON (See Instructions)
IA
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CUSIP No. 09074D103
|
SCHEDULE 13G/A
|
Page 4
of 8 Pages
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1
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NAME OF REPORTING
PERSONS
I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
Samuel D. Isaly
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2
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CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
(a)
o
(b)
o
|
|
3
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SEC USE ONLY
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4
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CITIZENSHIP OR PLACE OF ORGANIZATION
United States
|
NUMBER OF
SHARES
BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH
|
5
|
SOLE VOTING POWER
0
|
6
|
SHARED VOTING POWER
0
|
7
|
SOLE DISPOSITIVE POWER
0
|
8
|
SHARED DISPOSITIVE POWER
0
|
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
0
|
10
|
CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (See Instructions)
|
o
|
11
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PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
0.00%
|
12
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TYPE OF REPORTING PERSON (See Instructions)
IN
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CUSIP No. 09074D103
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SCHEDULE 13G/A
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Page
5 of 8 Pages
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Item 1.
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(a) Name of Issuer:
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Biotie Therapies Oyj
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(b) Address of Issuer’s Principal
Executive Offices:
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Joukahaisenkatu 6
FI-20520 Turku
Finland
Item 2.
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(a) Name of Person Filing
:
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This
Schedule 13G/A is being filed by each of the following persons (each a “Reporting Person”, and together, the
“Reporting Persons”):
(i) OrbiMed Capital GP V LLC ("GP V")
(ii) OrbiMed Advisors LLC ("Advisors")
(iii)
Samuel D. Isaly ("Isaly")
See
Exhibit A for the Reporting Persons’ agreement for a joint filing of a single statement on their behalf.
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(b) Address
of Principal Business Office:
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601 Lexington Avenue, 54th Floor
New York, NY 10022
Please
refer to Item 4 on each cover sheet for each Reporting Person
.
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(d) Title of Class of Securities:
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Common Stock
09074D103
CUSIP No. 09074D103
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SCHEDULE 13G/A
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Page 6
of 8 Pages
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Item 3.
Not Applicable
Item
4. Ownership:
(a) Amount beneficially owned:
See the response(s) to Item 9 on the attached cover page(s).
(b) Percent of class: See the response(s) to Item 11 on the attached cover page(s).
(i) Sole power to vote
or to direct the vote:See the response(s) to Item 5 on the attached cover page(s).
(ii) Shared power to vote
or to direct the vote: See the response(s) to Item 6 on the attached cover page(s).
(iii) Sole power to dispose
or to direct the disposition of: See the response(s) to Item 7 on the attached cover page(s).
(iv) Shared power to dispose
or to direct the disposition of: See the response(s) to Item 8 on the attached cover page(s).
Item
5. Ownership of Five Percent or Less of a Class.
If
this Statement is being filed to report the fact that as of the date hereof the Reporting Persons have ceased to be the beneficial
owner of more than five percent of the class of securities, check the following
x
Item
6. Ownership of More Than Five Percent on Behalf of Another Person
.