ART Advanced Research Technologies Inc. (ART) (TSX: ARA), a Canadian medical device company and a leader in optical molecular imaging products for the healthcare and pharmaceutical industries, announces its financial results for the third quarter ended September 30, 2008. ART reported revenues of $1,354,365 for the three-month period ended September 30, 2008, compared to $267,741 for the same quarter in 2007. For the nine-month period ended September 30, 2008, revenues were $3,809,146, compared to $703,907 for the same period in 2007. For the 2008 third quarter, the operating loss decreased by $364,326, or 17%, to $1,725,482, from $2,089,808 for the same period a year ago. For the nine-month period ended September 30, 2008, the operating loss was $4,150,766, compared to $7,566,216, for the nine-month period ended September 30, 2007. ART incurred a net loss for the three-month period ended September 30, 2008, of $1,545,940 or $0.02 per share, compared to $2,200,777 or $0.04 per share for the same quarter in 2007. For the nine-month period ended September 30, 2008, the net loss was $3,926,616 or $0.04 per share, compared to $6,939,854 or $0.12 per share, for the nine-month period ended September 30, 2007. All dollar amounts referenced herein are in U.S. dollars, unless otherwise stated.

2008 Third Quarter Highlights

- ART recognized revenue of $1.3 million from Optix� unit sales, and has a backlog representing approximately $600,000 in additional Optix unit sales.

- ART closed a private placement of approximately $6.0 million in preferred shares.

- ART continued to manage expenses carefully, resulting in a lower burn-rate compared to last year.

Post Quarter Events

- Final scans using the SoftScan� device were completed for the treatment monitoring pilot study at the Sunnybrook Health Sciences Centre in Toronto and, deeming these results as significant, the team at Sunnybrook will be submitting them for publication in a peer-reviewed journal.

Revenues

For the three-month period ended September 30, 2008, revenues were $1,354,365, compared to $267,741 for the same period ended September 30, 2007. Sales resulting from products amounted to $1,221,436 in the quarter ended September 30, 2008, compared to $267,741 for the same quarter of last year. Revenues resulting from sales of products for the nine-month period ended September 30, 2008 amounted to $2,464,825, compared to $703,907 for the same period of last year. The increase in product sales in 2008 when compared to 2007 is explained by the Company's transition to a direct distribution model. By selling directly to its customers, the Company now generates a higher revenue per system since it does not have to provide discounts to an exclusive distributor. During the quarter ended September 30, 2008, product sales resulted from the sale of four Optix� systems and Fenestra� products whereas for the same quarter in 2007, product sales included Fenestra products and add-ons for Optix systems only. The Company sold one service contract, and recognized a total of $132,929 in services and other revenues during the third quarter ended September 30, 2008. During the same period ended September 30, 2007, there were no sales resulting from services. During the nine-month period ended September 30, 2008, ART sold the first SoftScan unit, five Optix units, and add-ons for Optix systems that resulted in the conversion of two single-wavelength Optix systems to the MX2 version. Also, the Company recognized revenues totaling $1,075,517 from services rendered on behalf of GE, as ART is completing the transition out of the Optix distribution agreement with GE. During the nine-month period ended September 30, 2007, there were no sales of add-ons for Optix systems that resulted in the conversion of single-wavelength Optix systems to the MX2 version and there were no sales resulting from services.

Gross Margin

During the three-month and nine-month periods ended September 30, 2008, ART generated a gross margin of 45% and 62% respectively from the sales of its products, compared to 66% and 55% for the same periods in the previous year. The gross margin generated on the sales of services and other revenues was 92% and 95% respectively for the three-month and nine-month periods ended September 30, 2008. No gross margin on sales of services is recorded for 2007, as there were no sales of service contracts during the same period in 2007. The decrease of the gross margin ratio for the three-month period ended September 30, 2008, compared to the same quarter of the previous year, is primarily due to a different sales product mix. For the three-month period ended September 30, 2008, the lower gross margin ratio is explained by the fact that ART accounted for the cost of four systems during the current period, as compared to last year when the Company mainly sold add-ons, for which a higher gross margin ratio is typically recognized. The increase in the gross margin ratio during the nine-month period ended September 30, 2008, compared to the same period in 2007 resulted from services and other revenues as well as the sale of the SoftScan unit in the first quarter of 2008, where the gross margin on this unit represented almost 100% of the sale, given that this unit had been sold as a prototype and therefore expensed as incurred in previous years.

Operating Expenses

The Company's research and development ("R&D") expenditures for the three-month period ended September 30, 2008, net of investment tax credits, amounted to $637,713, compared to $1,093,057 for the same period ended September 30, 2007. For the nine-month period ended September 30, 2008, R&D expenditures, net of investment tax credits, were $2,110,642, compared to $3,990,556 for the nine-month period ended September 30, 2007. The R&D expenditures during the three-month and the nine-month periods ended September 30, 2008, decreased by 42% and 47% respectively, compared to the same periods in 2007. The decrease was related to the medical sector given that the SoftScan program reached important approval milestones in the first quarter of 2007 by obtaining the CE marking for Europe. As well, in the preclinical sector, a decrease in R&D expenses was due to the completion of the project leading to the new Optix MX2 system. The costs associated with the achievement of these milestones, therefore, did not have to be incurred again in 2008. As a part of its R&D activities, ART continued to support the Optix product as R&D teams collaborated with clients for the development of applications using the new MX2 version of the system.

Selling, general, and administrative ("SG&A") expenses for the three-month period ended September 30, 2008, totaled $1,523,315, compared to $1,088,071 for the same period ended September 30, 2007. For the nine-month period ended September 30, 2008, SG&A expenses were $4,275,379, compared to $3,706,266 for the nine-month period ended September 30, 2007. The SG&A expenses increased by $435,244 during the three-month period ended September 30, 2008 and by $569,113 in the nine-month period ended September 30, 2008, compared to the same periods of 2007. The increase of the SG&A expenses during the three-month and the nine-month periods was mainly due to the hiring of the new direct sales force, which was effective in the first quarter of 2008, and the direct marketing expenses incurred to support the commercialization of the Optix, SoftScan and Fenestra products.

Net Loss

As a result of the foregoing factors, the net loss for the three-month period ended September 30, 2008, was $1,545,940 or $0.02 per share, compared to $2,200,777 or $0.04 per share for the quarter ended September 30, 2007. For the nine-month period ended September 30, 2008, the net loss was $3,926,616 or $0.04 per share, compared to $6,939,854 or $0.12 per share, for the nine-month period ended September 30, 2007.

Financial Position

As at September 30, 2008, ART has $5,018,947 in cash and cash equivalents, and a working capital of $6,527,294.

The financial statements, accompanying notes to the financial statements, and Management's Discussion and Analysis for the three-month period ended September 30, 2008, will be available online at www.sedar.com, or at www.art.ca, in the "Investors" section. Summary financial tables are provided below. A detailed list of the risks and uncertainties affecting the Company can be found in the Management's Discussion and Analysis for the year ended December 31, 2007, and in the Company's most recent Annual Information Form, available on SEDAR at www.sedar.com.

Conference Call

ART will host a conference call today at 5:00 PM (EDT). The telephone number to access the conference call is (514) 861-1531 when dialing within the Montreal area, or (877) 667-7766 for the rest of North America. Outside of North America, please dial (514) 861-1531. A replay of the call will be available until November 25, 2008. To listen to the replay from the Montreal area, please dial (514) 861-2272, or, (800) 408-3053 for the rest of North America. From outside of North America, please dial (514) 861-2272. The access code for the replay is 3273598#.

About ART

ART Advanced Research Technologies Inc. is a leader in molecular imaging products for the healthcare and pharmaceutical industries. ART has developed products in medical imaging, medical diagnostics, disease research, and drug discovery with the goal of bringing new and better treatments to patients faster. The Optix� optical molecular imaging system, designed for monitoring physiological changes in living systems at the preclinical study phases of new drugs, is used by industry and academic leaders worldwide. The SoftScan� optical medical imaging device is designed to improve the diagnosis and treatment of breast cancer. Finally, the Fenestra� line of molecular imaging contrast products provides image enhancement for a wide range of preclinical Micro CT applications allowing scientists to see greater detail in their imaging studies, with potential extension into other major imaging modalities. ART is commercializing some of these products in a global strategic alliance with GE Healthcare, a world leader in mammography and imaging. ART's shares are listed on the TSX under the ticker symbol ARA. For more information on ART, visit our website at www.art.ca.

This press release may contain forward-looking statements subject to risks and uncertainties that would cause actual events to differ materially from expectations. These risks and uncertainties are described in the most recent Annual Information Form and the financial statements for the year ended December 31, 2007, available on SEDAR (www.sedar.com).

Financial Statements (in U.S. dollars)


ART Advanced Research Technologies Inc.
Balance sheets
(In U.S. dollars)
                                             September 30,    December 31,
                                                     2008            2007
                                               (unaudited)
-------------------------------------------------------------------------
ASSETS
Current assets
  Cash                                         $1,631,977        $561,325
  Term deposits, 2.75% maturing in October
   2008 (2007 - 4.05% maturing in January
   2008)                                        3,386,970       3,026,329
  Accounts receivable                           2,303,600       1,768,146
  Investment tax credits receivable               755,430       1,558,709
  Inventories                                   1,350,241       1,510,499
  Prepaid expenses                                815,471         260,199
-------------------------------------------------------------------------
                                               10,243,689       8,685,207
Property and equipment                            505,525         551,210
Patents                                         1,774,108       2,135,855
Deferred development costs                      2,304,556       1,268,438
-------------------------------------------------------------------------
                                              $14,827,878     $12,640,710
-------------------------------------------------------------------------
-------------------------------------------------------------------------
LIABILITIES
Current liabilities
  Bank loan                                       566,091         605,266
  Accounts payable and accrued liabilities      2,851,705       2,652,219
  Deferred revenues                               110,579         156,167
  Deferred grant                                  147,962         152,305
  Current portion of obligations under
   capital leases                                  40,058               -
-------------------------------------------------------------------------
                                                3,716,395       3,565,957

Obligations under capital leases                   55,823               -
-------------------------------------------------------------------------
-------------------------------------------------------------------------
                                                3,772,218       3,565,957
-------------------------------------------------------------------------
-------------------------------------------------------------------------
SHAREHOLDERS' EQUITY
Share capital and share purchase warrants      39,142,553      32,217,942
Contributed surplus                             4,823,965       4,537,336
Deficit                                       (35,518,077)    (31,007,264)
Accumulated other comprehensive income          2,607,219       3,326,739
-------------------------------------------------------------------------
                                               11,055,660       9,074,753
-------------------------------------------------------------------------
                                              $14,827,878     $12,640,710
-------------------------------------------------------------------------
-------------------------------------------------------------------------



ART Advanced Research Technologies Inc.
Shareholders's Equity
As at September 30, 2008
(In U.S. dollars)
                                   Common Shares         Preferred Shares
-------------------------------------------------------------------------
                            Number        Amount      Number       Amount
-------------------------------------------------------------------------
Balance as at January 1,
 2007                   52,248,981   $14,561,504   8,341,982   $7,907,043
Net loss
Translation adjustment
-------------------------------------------------------------------------
Comprehensive loss
-------------------------------------------------------------------------
-------------------------------------------------------------------------

Issue of shares for
 business acquisition      162,369        95,262
Issue of shares for
 cash                   42,129,242     8,373,257
Issue of share purchase
 warrants
Share and share purchase
 warrant issue expenses
Stock-based compensation
Expired warrants
-------------------------------------------------------------------------
Balance as at December
 31, 2007               94,540,592   $23,030,023   8,341,982   $7,907,043
-------------------------------------------------------------------------
-------------------------------------------------------------------------
(unaudited)
Balance as at
 January 1, 2008        94,540,592   $23,030,023   8,341,982   $7,907,043
Net loss
Translation adjustment
-------------------------------------------------------------------------
Comprehensive income
-------------------------------------------------------------------------
-------------------------------------------------------------------------

Issue of shares for
 cash                                             53,101,296    7,100,000
Share issue expenses
Stock-based compensation
Expired warrants
-------------------------------------------------------------------------
Balance as at September
 30, 2008               94,540,592   $23,030,023  61,443,278  $15,007,043
-------------------------------------------------------------------------
-------------------------------------------------------------------------


                                                            Share Capital
                                                                and Share
                                                                 Purchase
                                                  Warrants       Warrants
-------------------------------------------------------------------------
                                      Number        Amount          Total
-------------------------------------------------------------------------
Balance as at January 1, 2007      3,958,523    $1,562,623    $24,031,170
Net loss
Translation adjustment
-------------------------------------------------------------------------
Comprehensive loss
-------------------------------------------------------------------------
-------------------------------------------------------------------------

Issue of shares for business
 acquisition                                                       95,262
Issue of shares for cash                                        8,373,257
Issue of share purchase warrants   2,175,841       497,288        497,288
Share and share purchase warrant
 issue expenses
Stock-based compensation
Expired warrants                  (1,278,573)     (779,035)      (779,035)
-------------------------------------------------------------------------
Balance as at December 31, 2007    4,855,791    $1,280,876    $32,217,942
-------------------------------------------------------------------------
-------------------------------------------------------------------------
(unaudited)
Balance as at January 1, 2008      4,855,791    $1,280,876    $32,217,942
Net loss
Translation adjustment
-------------------------------------------------------------------------
Comprehensive income
-------------------------------------------------------------------------
-------------------------------------------------------------------------

Issue of shares for cash                                        7,100,000
Share issue expenses
Stock-based compensation
Expired warrants                    (594,907)     (175,389)      (175,389)
-------------------------------------------------------------------------
Balance as at September 30, 2008   4,260,884    $1,105,487    $39,142,553
-------------------------------------------------------------------------
-------------------------------------------------------------------------


                                                 Accumulated
                                                       Other
                    Contributed                Comprehensive
                        Surplus        Deficit        Income        Total
-------------------------------------------------------------------------
Balance as at
 January 1, 2007     $3,586,059   $(21,247,643)   $1,841,127   $8,210,713
Net loss                            (8,623,447)                (8,623,447)
Translation
 adjustment                                        1,485,612    1,485,612
-------------------------------------------------------------------------
Comprehensive loss                  (8,623,447)    1,485,612   (7,137,835)
-------------------------------------------------------------------------
-------------------------------------------------------------------------

Issue of shares for
 business acquisition                                              95,262
Issue of shares for
 cash                                                           8,373,257
Issue of share
 purchase warrants                                                497,288
Share and share
 purchase warrant
 issue expenses                     (1,136,174)                (1,136,174)
Stock-based
 compensation           172,242                                   172,242
Expired warrants        779,035                                         -
-------------------------------------------------------------------------
Balance as at
 December 31, 2007   $4,537,336   $(31,007,264)   $3,326,739   $9,074,753
-------------------------------------------------------------------------
-------------------------------------------------------------------------
(unaudited)
Balance as at
 January 1, 2008     $4,537,336   $(31,007,264)   $3,326,739   $9,074,753
Net loss                            (3,926,616)                (3,926,616)
Translation adjustment                              (719,520)    (719,520)
-------------------------------------------------------------------------
Comprehensive income                (3,926,616)     (719,520)  (4,646,136)
-------------------------------------------------------------------------
-------------------------------------------------------------------------

Issue of shares for
 cash                                                           7,100,000
Share issue expenses                  (584,197)                  (584,197)
Stock-based
 compensation           111,240                                   111,240
Expired warrants        175,389                                         -
-------------------------------------------------------------------------
Balance as at
 September 30, 2008  $4,823,965   $(35,518,077)   $2,607,219  $11,055,660
-------------------------------------------------------------------------
-------------------------------------------------------------------------



ART Advanced Research Technologies Inc.
Operations
(In U.S. dollars)
(Unaudited)
                      Three-month Periods ended  Nine-month Periods ended
                                   September 30              September 30
-------------------------------------------------------------------------
                               2008        2007         2008         2007
-------------------------------------------------------------------------
Sales
  Products               $1,221,436    $267,741   $2,464,825     $703,907
  Services and other
   revenues                 132,929           -    1,344,321            -
-------------------------------------------------------------------------
                          1,354,365     267,741    3,809,146      703,907
-------------------------------------------------------------------------
Cost of sales
  Products                  672,385      91,120      924,580      313,312
  Services and other
   revenues                  11,051           -       68,151            -
-------------------------------------------------------------------------
                            683,436      91,120      992,731      313,312
-------------------------------------------------------------------------
Gross margin                670,929     176,621    2,816,415      390,595
-------------------------------------------------------------------------
Operating expenses
  Research and
   development, net of
   investment tax
   credits                  637,713   1,093,057    2,110,642    3,990,556
  Selling, general
   and administrative     1,523,315   1,088,071    4,275,379    3,706,266
  Amortization              235,383      85,301      581,160      259,989
-------------------------------------------------------------------------
                          2,396,411   2,266,429    6,967,181    7,956,811
-------------------------------------------------------------------------
Operating loss            1,725,482   2,089,808    4,150,766    7,566,216
Other expenses
 (revenues)                (179,542)    110,969     (224,150)     184,943
-------------------------------------------------------------------------
Loss from operations
 before income taxes      1,545,940   2,200,777    3,926,616    7,751,159
Current income taxes
 (recovery)                       -           -            -     (881,305)
-------------------------------------------------------------------------
Net loss                 $1,545,940  $2,200,777   $3,926,616   $6,939,854
-------------------------------------------------------------------------
-------------------------------------------------------------------------
Basic and diluted net
 loss per share               $0.02       $0.04        $0.04        $0.12
-------------------------------------------------------------------------
-------------------------------------------------------------------------
Basic and diluted
 weighted average
 number of common
 shares outstanding      94,540,592  63,290,592   94,540,592   60,148,336
-------------------------------------------------------------------------
-------------------------------------------------------------------------
Number of common
 shares outstanding,
 end of period           94,540,592  63,290,592   94,540,592   63,290,592
-------------------------------------------------------------------------
-------------------------------------------------------------------------



ART Advanced Research Technologies Inc.
Cash Flows
(In U.S. dollars)
(Unaudited)
                      Three-month Periods ended  Nine-month Periods ended
                                   September 30              September 30
-------------------------------------------------------------------------
                               2008        2007         2008         2007
-------------------------------------------------------------------------
OPERATING ACTIVITIES

Net loss                $(1,545,940)$(2,200,777) $(3,926,616)$(6,939,854)
Items not affecting cash
  Amortization              235,383      85,301      581,160      259,988
  Stock-based
   compensation              37,080      28,274      111,240      129,274
  Gain on disposal of
   fixed assets                (835)          -      (27,542)           -
Net changes in working
 capital items
  Accounts receivable      (333,907)    (90,352)    (669,177)    (229,936)
  Investment tax credits
   receivable              (155,018)   (178,725)     748,638     (461,078)
  Inventories               257,283      19,805       57,806       19,866
  Prepaid expenses          (44,314)     55,568     (603,903)      70,703
  Accounts payable and
   accrued liabilities      792,624    (165,761)     365,924   (1,096,831)
  Deferred revenues         (82,375)          -      (34,848)           -
  Deferred grant                  -           -        5,821            -
  Income taxes payable            -           -            -     (811,304)
-------------------------------------------------------------------------
Cash flows from operating
 activities                (840,019) (2,446,667)  (3,391,497)  (9,059,172)
-------------------------------------------------------------------------
INVESTING ACTIVITIES
Short-term investments            -   2,017,154            -     (742,305)
Additions of property
 and equipment               (1,657)    (16,629)     (11,402)    (112,780)
Proceeds from disposal of
 property and equipment       1,617           -       60,789            -
Patents                     (27,466)          -     (159,309)           -
Deferred development
 costs                     (471,601)   (251,829)  (1,235,147)    (493,635)
-------------------------------------------------------------------------
Cash flows from investing
 activities                (499,107)  1,748,696   (1,345,069)  (1,348,720)
-------------------------------------------------------------------------
FINANCING ACTIVITIES
Bank loan                         -                        -      546,398
Repayment of obligations
 under capital leases        (9,761)          -      (27,756)           -
Issue of convertible
 preferred shares         6,000,000           -    7,100,000            -
Issue of common shares
 and share purchase
 warrants                         -           -            -    3,887,999
Equity issue expenses      (502,004)          -     (584,197)    (195,403)
-------------------------------------------------------------------------
Cash flows from financing
 activities               5,488,235           -    6,488,047    4,238,994
Effect of foreign
 currency translation
 adjustments               (256,497)     59,985     (320,188)     316,568
-------------------------------------------------------------------------
                          5,231,738      59,985    6,167,859    4,555,562
-------------------------------------------------------------------------
Net increase (decrease)
 in cash and cash
 equivalents              3,892,612    (637,986)   1,431,293   (5,852,330)
Cash and cash equivalents,
 beginning of period      1,126,335   1,332,592    3,587,654    6,546,936
-------------------------------------------------------------------------
Cash and cash equivalents,
 end of period           $5,018,947    $694,606   $5,018,947     $694,606
-------------------------------------------------------------------------
-------------------------------------------------------------------------
CASH AND CASH
 EQUIVALENTS
Cash                     $1,631,977    $544,606   $1,631,977     $544,606
Term deposits             3,386,970     150,000    3,386,970      150,000
-------------------------------------------------------------------------
                         $5,018,947    $694,606   $5,018,947     $694,606
-------------------------------------------------------------------------
-------------------------------------------------------------------------
Supplemental disclosure
 of cash flow
 information
Interest paid               $13,113     $69,912      $46,128      $93,344
Interest received           $15,521     $17,315      $51,661      $44,193
-------------------------------------------------------------------------
The accompanying notes are an integral part of the financial statements.

Contacts: ART Advanced Research Technologies Inc. Jacques Bedard Chief Financial Officer 514-832-0777 jbedard@art.ca www.art.ca

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