TIDMNFX

RNS Number : 5107V

Nuformix PLC

14 December 2021

Nuformix plc

("Nuformix", the "Company" or the "Group")

Half year Report

14 December 2021: Nuformix plc (LSE: NFX), a pharmaceutical development company targeting unmet medical needs in fibrosis and oncology via drug repurposing, announces its unaudited results for the six months ended 30 September 2021.

Operational highlights (including post-period end)

 
 --   Gross proceeds of GBP1.565 million (net GBP1.4 million) raised 
       from the placing of new ordinary shares in March 2021 have 
       been used to fund R&D work to advance the pipeline assets 
       of NXP002 (pre-clinical stage) and NXP004 (research phase) 
 --   Successfully performed a number of pre-clinical studies on 
       NXP002, which is the lead asset being developed for the treatment 
       of Idiopathic Pulmonary Fibrosis ("IPF"), to generate a robust 
       data package. Studies on the technical feasibility of inhalation 
       and the pharmacokinetic / pharmacodynamic profile of NXP002 
       after inhalation in the rat have, in the opinion of the Company's 
       Directors, been positive to date and endorse the further 
       progression of this asset. The final study in the data package 
       on the durability of the pharmacodynamic response is expected 
       to readout in early 2022 
 --   NXP002 patent application granted in the USA, which is the 
       most important territory for IPF 
 --   Filed a US patent application on 10 November 2021 in relation 
       to NXP004, that represents new forms of a blockbuster oncology 
       drug, which has identified a new family of co-crystals with 
       benefits over the original drug 
 --   Licensing agreement signed with Oxilio Ltd on 10 September 
       2021 for the development and commercialisation of NXP001 
       for oncology indications 
 --   Leadership team enhanced with the appointment of Dr Alastair 
       Riddell as Non-Executive Chairman (with post-period appointment 
       as Executive Chairman from 1 December 2021), who brings significant 
       pharma and biotech experience in R&D, corporate development 
       and general leadership 
 --   Dr Anne Brindley (CEO) resigned in July 2021 and will be 
       leaving the Company at the end of her six-month notice period. 
       Dr Joanne Holland resigned as a director and left the Company 
       as an employee at the end of May 2021 but has continued as 
       a consultant advising on physical form science and research 
 

Financial Highlights

 
 --   Total revenue of GBP50,000 (30 September 2020: GBP195,550) 
 --   Loss before tax GBP449,022 (30 September 2020: loss of GBP475,874) 
 --   Loss on ordinary activities (after tax credit) of GBP449,022 
       (30 September 2020: loss of GBP474,659) 
 --   Loss per share 0.08p (30 September 2020: 0.10p) 
 --   Net assets of GBP5,250,968 (30 September 2020: GBP4,301,236) 
       including GBP1,071,831 of cash and cash equivalents (30 September 
       2020: GBP216,412) 
 

Dr Alastair Riddell, Executive Chairman of Nuformix, said: "The new positive data sets on NXP002, patent progress on NXP004 and the licensing deal for NXP001 form the basis for further value creation in the next 12 months. Both our current lead assets address billion-dollar markets in fibrosis and oncology. The results have given the Board the confidence to progress further work on our products and investment in additional business development resource for the Company."

Dr Anne Brindley, CEO of Nuformix, said: "We have made significant progress on all three of our assets including successfully completed the licensing deal for NXP001 with Oxilio, as well as significantly advancing the data package on NXP002 that has shown positive data to date and filing a new patent application on NXP004. We have achieved this with very prudent use of funds ensuring the Company is on a firm financial footing for the foreseeable future. Although regretfully I am moving on from Nuformix, I remain very optimistic that Nuformix has assets of value that the Group can advance to further develop the company and I wish the Board and the company much success in these endeavours."

Enquiries:

 
Nuformix plc                                           via Walbrook 
Dr Alastair Riddell, Executive Chairman 
Dr Anne Brindley, CEO 
 
Allenby Capital Limited                        +44 (0) 20 3328 5656 
Nick Athanas / George Payne (Corporate 
 Finance) 
Stefano Aquilino / Matt Butlin (Sales 
 and Corporate Broking) 
 
Walbrook PR                                 nuformix@walbrookpr.com 
                                                                 or 
                                                +44 (0)20 7933 8780 
Anna Dunphy / Phillip Marriage             Tel: +44 (0)7876 741 001 
                                                                  / 
                                                +44 (0)7867 984 082 
 

About Nuformix

Nuformix is a pharmaceutical development company targeting unmet medical needs in fibrosis and oncology via drug repurposing. The Company aims to use its expertise in discovering, developing and patenting novel drug forms, with improved physical properties, to develop new products in new indications that are, importantly, differentiated from the original (by way of dosage, delivery route or presentation), thus creating new and attractive commercial opportunities. Nuformix has an early-stage pipeline of preclinical and Phase 1-ready assets with potential for significant value and early licensing opportunities.

Nuformix plc shares are traded on the London Stock Exchange's Official List under the ticker: NFX. For more information, please visit www.nuformix.com .

Executive Chairman's statement

Operational review

NXP002 (new form of tranilast) - Idiopathic Pulmonary Fibrosis (IPF)

NXP002 is the Group's pre-clinical lead asset and a potential novel inhaled treatment for IPF. It is a proprietary, new form of the drug tranilast, to be delivered in an inhaled formulation. IPF is a devastating lung disease associated with a higher mortality rate than many cancers and where there is a need for additional treatment options. Thus IPF represents a high unmet medical need and a significant commercial opportunity. Tranilast has a long history of safe use as an oral drug for allergies but there is evidence that supports its potential in fibrosis, including IPF. NXP002 is differentiated as it is a new form of tranilast that is being formulated for delivery direct to the lungs by inhalation, a new route of administration for this drug. The inhalation route is a well-known strategy for treatment of lung diseases to yield greater efficacy and reduce systemic side-effects compared to oral treatment. Nuformix has filed two patent applications on new forms of tranilast, one of which is granted globally and a second has been issued (granted) in the USA. The positioning of such an inhaled treatment for IPF could be either added to standard of care or administered as a monotherapy.

Within the last six months, since the fundraise in March 2021, the Group has utilised these proceeds to generate a robust data package with the goal of increasing the value of this asset and rendering it more attractive to licensing partners. The Company has successfully progressed studies on NXP002 as follows:

 
 --   Manufactured a supply of the active ingredient NXP002 to be 
       used in formulation development activities, nebulisation feasibility 
       studies and in vivo studies 
 --   Progressed formulation and nebulisation studies and demonstrated 
       that it is feasible to formulate NXP002 into a simple and 
       stable solution which has suitable properties for delivery 
       via nebulisation. The data generated on these formulations 
       also show that the drug can be efficiently delivered in the 
       right particle size range for lung delivery using off-the-shelf 
       and commonly used nebuliser devices. Thus, the Directors of 
       the Company believe that the delivery of NXP002 by nebulisation 
       is feasible 
 --   Progressed several in vivo pharmacokinetic and pharmacodynamic 
       studies of NXP002 formulated as a solution for inhalation 
       (nebulisation) and delivered to the rat 
                                  --                               The first of the in vivo studies evaluated the 
                                                                   pharmacokinetics 
                                                                   of NXP002 when delivered by nebulisation to rats. 
                                                                   This 
                                                                   study demonstrated that NXP002 can be efficiently 
                                                                   delivered 
                                                                   to the lung, achieving significant drug levels, 
                                                                   whilst 
                                                                   limiting systemic exposure compared to oral dosing 
                                  --                               The second in vivo study evaluated the 
                                                                   pharmacodynamics 
                                                                   of NXP002 when delivered by nebulisation. This 
                                                                   study 
                                                                   showed that inhaled NXP002 could dose-dependently 
                                                                   regulate 
                                                                   the production of fibrosis-relevant mediators 
 --   The final planned study as part of the NXP002 pre-clinical 
       data package is an in vivo study investigating the durability 
       of the pharmacodynamic effect. This study is ongoing and the 
       Company anticipates receiving the data for this study in early 
       2022. 
 

Overall, the Board is encouraged by the progress of the studies and the positive data generated to date and is considering next steps, including potential further R&D studies to add further value and licensing activities.

NXP001 (new form of aprepitant) - Oncology

NXP001 is a proprietary new form of the drug aprepitant that is currently marketed as a product in the oncology supportive care setting (chemotherapy induced nausea and vomiting). A disadvantage of aprepitant is that its sub-optimal properties necessitate a complex formulation. The Group has discovered new forms of aprepitant (NXP001) with improved properties and it has been granted patents on these new forms. Literature data suggests that aprepitant could have benefits in oncology, i.e., beyond the currently marketed indications.

To date, the Group has conducted preclinical studies and a Phase 1 study, which demonstrated bioavailability of NXP001, similar to the marketed product but without requiring a complex formulation. Further refinement of the formulation will be required ahead of initiating any future Phase 1 studies.

On 23 September 2020, Oxilio, a privately held pharmaceutical development company, was granted a six-month option to license NXP001 globally for repurposing in oncology. On 23 March 2021, Oxilio exercised the option and on 10 September 2021 a global license deal was executed. As a result, Nuformix has licensed its patent estate and know-how on NXP001 in return for an upfront payment, development milestones and a royalty on net sales, capped at GBP2 million per annum.

NXP004 (new forms of undisclosed drug) - Oncology

The Group has discovered novel forms of an undisclosed marketed oncology drug that is approved globally for the treatment of several cancers, which has significant sales (more than GBP1 billion per annum in 2020) and is showing further sales growth. The Group filed one patent application in September 2020 on new forms of this drug and has utilised certain of the proceeds from the March 2021 placing to do further research on novel forms. This research has been successful, identifying a new family of co-crystal forms and on 10 November 2021, post period, the Company filed a second patent application. This application complements the previous patent application on NXP004 co-crystals, thus expanding the Company's intellectual property portfolio. If the patent applications on these new forms are granted, there is potential for patent expiry to extend to 2040/2041. The Group will seek to license NXP004 to the originator of the marketed drug to potentially extend their patent protection, thus potentially adding significant value for the originator.

Board changes

In the period from April 2021 to September 2021 a number of Board changes have occurred:

 
 --   May 2021 - appointment of Dr Alastair Riddell as Non-Executive 
       Chairman, replacing Dr Chris Blackwell who resigned in February 
       2021 
 --   May 2021 - resignation of Dr Karl Keegan as Non-Executive 
       Director 
 --   May 2021 - resignation of Dr Joanne Holland as Chief Scientific 
       Officer; however, Joanne remains a consultant to Nuformix 
       and is supporting physical form research and science on Nuformix 
       assets 
 --   July 2021 - resignation of Dr Anne Brindley as CEO. Anne 
       has continued to work for the Company through her six-month 
       notice period 
 

On 1 December 2021 Dr Alastair Riddell was appointed as Executive Chairman to ensure there is a suitable executive in place for when Anne Brindley leaves the Company.

Outlook

The success of the fundraise earlier in the year has enabled the Company to continue to advance and exploit the current assets within the portfolio through additional R&D and business development activities as set out above. R&D studies have progressed successfully on both NXP002 and NXP004, while business development activities secured the license agreement for NXP001 and therefore good progress has been made on all fronts. Moreover, the successful fundraise has provided a good cash runway for the Company to fund limited operations for the foreseeable future.

The strategy of the Group is to continue to increase the value of its existing assets while maintaining tight control of costs, including conducting business development / licensing activities using a structured and data-driven approach, with the goal of seeking global licensing deals. The positive data from the R&D studies performed in the last six months has increased the Board's confidence that the Nuformix assets have significant value and thus further investment in and progression of these assets are warranted.

Financial Review

In the first half of the financial year, the Board has continued to focus expenditure on R&D activities that add value to the current assets while optimising the operation to minimise administrative expenditure and the operational cost-base. Revenue was received from the second instalment of the upfront payment from Oxilio on execution of the full licensing agreement for NXP001.

Dr Alastair Riddell

Executive Chairman

14 December 2021

Nuformix plc

Unaudited Interim Results

Consolidated Income Statement and Statement of Comprehensive Income for the six months ended 30 September 2021

 
                                              6 months         6 months 
                                                ending           ending     Year ending 
                                          30 September     30 September        31 March 
                                                  2021             2020            2021 
                                             Unaudited        Unaudited         Audited 
                                  Note             GBP              GBP             GBP 
 Revenue                                        50,000          195,550         195,550 
 
 Cost of sales                                 (1,695)        (115,507)        (62,307) 
                                        --------------  ---------------  -------------- 
 
 Gross profit                                   48,305           80,043         133,243 
 
 Total administrative expenses               (497,327)        (554,822)     (1,507,221) 
 
 Other operating income                              -            1,300           1,300 
                                        --------------  ---------------  -------------- 
 
 Operating loss                              (449,022)        (473,479)     (1,372,678) 
 
 Finance costs                                       -          (2,395)         (3,054) 
                                        --------------  ---------------  -------------- 
 
 Loss before tax                             (449,022)        (475,874)     (1,375,732) 
 
 Income tax receipt                                  -            1,215         122,235 
 
 Loss for the period and total 
  comprehensive income for the 
  period                                     (449,022)        (474,659)     (1,253,497) 
                                        ==============  ===============  ============== 
 
 Loss per share - basic and 
  diluted                           4            0.08p            0.10p           0.22p 
 

Nuformix plc

Registration number: 09632100

Unaudited Interim Results

Consolidated Statement of Financial Position as at 30 September 2021

 
                                         30 September   30 September      31 March 
                                                 2021           2020          2021 
                                  Note      Unaudited      Unaudited       Audited 
                                                  GBP            GBP           GBP 
 Assets 
 Non-current assets 
 Property, plant and equipment     5              698         64,661           957 
 Intangible assets                 6        4,168,640      4,225,381     4,186,868 
                                            4,169,338      4,290,042     4,187,825 
                                        -------------  -------------  ------------ 
 Current assets 
 Trade and other receivables                   53,663         88,956        32,260 
 Income tax asset                             121,020              -       121,020 
 Cash and cash equivalents                  1,071,831        216,411     1,669,780 
                                            1,246,514        305,368     1,823,060 
                                        -------------  -------------  ------------ 
 
 Total assets                               5,415,852      4,595,410     6,010,885 
                                        =============  =============  ============ 
 
 Equity and liabilities 
 Equity 
 Share capital                     7          591,609        490,145       591,609 
 Share premium                              6,384,835      4,480,400     6,384,835 
 Merger relief reserve                     10,950,000     10,950,000    10,950,000 
 Reverse acquisition reserve              (8,005,195)    (8,005,195)   (8,005,195) 
 Share option reserve                       2,019,681      1,847,988     2,005,952 
 Retained earnings                        (6,689,962)    (5,462,102)   (6,240,940) 
                                        -------------  -------------  ------------ 
 
 Total equity                               5,250,968      4,301,236     5,686,261 
                                        -------------  -------------  ------------ 
 
 Current liabilities 
 Trade and other payables                     164,884        243,846       324,624 
 Loans and borrowings                               0         50,328             0 
                                        -------------  -------------  ------------ 
                                              164,884        294,174       324,624 
 
 Total equity and liabilities               5,415,852      4,595,410     6,010,885 
                                        =============  =============  ============ 
 

Nuformix plc

Unaudited Interim Results

Consolidated Statement of Changes in Equity for the six months ended 30 September 2021

 
                             Share        Share        Merger             Reverse            Share            Retained        Total 
                           capital      premium        Relief             acquisition       option            earnings          GBP 
                               GBP          GBP       Reserve             reserve          reserve                 GBP 
                                                          GBP 
                                                                                  GBP 
  At 31 March 2020         490,145    4,480,400    10,950,000             (8,005,195)    1,814,613         (4,987,443)    4,742,520 
Loss for the half-year 
 and total                       -            -             -                       -            -           (474,659)    (474,659) 
comprehensive loss 
 Issue of share capital 
 Share and warrant 
 based                                                                                           -                                - 
 payment                         -            -             -                       -       33,375                   -       33,375 
                         ---------  -----------  ------------  ----------------------  -----------  ------------------  ----------- 
 
  As at 30 September 
  2020                     490,145    4,480,400    10,950,000             (8,005,195)    1,847,988         (5,462,102)    4,301,236 
Loss for the half-year 
 and total 
 comprehensive 
 loss                            -            -             -                       -            -           (778,838)    (778,838) 
Issue of share capital     101,464    2,113,535             -                       -            -                   -    2,214,999 
 Share issue costs                    (209,100)                                                                           (209,100) 
Share and warrant based 
 payment                         -            -             -                       -      157,964                   -      157,964 
                                                                                                                                  - 
                                 -            -             -                       -            -                   - 
                         ---------  -----------  ------------  ----------------------  -----------  ------------------  ----------- 
 
  At 31 March 2021         591,609    6,384,835    10,950,000             (8,005,195)    2,005,952         (6,240,940)    5,686,261 
Loss for the half-year 
 and total 
 comprehensive 
 income                          -            -             -                       -            -           (449,022)    (449,022) 
Share and warrant based 
 payment                         -            -             -                       -       13,729                   -       13,729 
                         ---------  -----------  ------------  ----------------------  -----------  ------------------  ----------- 
 
  As at 30 September 
  2021                     591,609    6,384,835    10,950,000             (8,005,195)    2,019,681         (6,689,962)    5,250,968 
                         =========  ===========  ============  ======================  ===========  ==================  =========== 
 

Nuformix plc

Unaudited Interim Results

Consolidated Statement of Cash Flows for the six months ended 30 September 2021

 
                                                      6 months         6 months 
                                                        ending           ending     Year Ended 
                                                  30 September     30 September       31 March 
                                                          2021             2020           2021 
                                                     Unaudited        Unaudited        Audited 
                                                           GBP              GBP            GBP 
 Cash flows from operating activities 
 Loss for the year                                   (449,022)        (474,659)    (1,253,497) 
 Adjustments to cash flows from non-cash 
  items 
 Depreciation and amortisation                          18,488           41,337         93,052 
 Loss on disposal of plant, property and 
  equipment                                                  -                -          6,179 
 Finance costs/ (income)                                     -            2,395          3,054 
 Income tax expense                                          -                -      (122,235) 
 Share and warrant based payment                        13,729           33,375        191,339 
                                                     (416,805)        (397,552)    (1,082,108) 
 Working capital adjustments 
 (Increase) decrease in trade and other 
  receivables                                         (21,403)          (9,460)         47,237 
 Increase (decrease) in trade and other 
  payables                                           (159,740)         (89,739)         16,099 
                                                --------------  ---------------  ------------- 
 Cash generated from operations                      (597,948)        (496,751)    (1,018,772) 
 Income taxes (paid)/received                                           172,391        173,606 
                                                --------------  ---------------  ------------- 
 Net cash flow from operating activities             (597,948)        (324,360)      (845,166) 
 
 Cash flows from investing activities 
 Acquisitions of property plant and equipment                -            (605)          (605) 
 Disposals of property plant and equipment                   -                -         44,322 
 Net cash flows from investing activities                    -            (605)         43,717 
                                                --------------  ---------------  ------------- 
 
 Cash flows from financing activities 
 Proceeds of share issue                                     -                -      2,005,899 
 Interest paid                                                          (2,395)        (3,054) 
 Reduction in other loans                                    -                -       (75,388) 
 Net cash flows from financing activities                    -          (2,395)      1,927,457 
                                                --------------  ---------------  ------------- 
 
 Net (decrease)/increase in cash and cash 
  equivalents                                        (597,948)        (327,360)      1,126,008 
 
 Cash and cash equivalents at start of 
  period                                             1,669,780          543,772        543,772 
 Cash and cash equivalents at end of period          1,071,832          216,412      1,669,780 
                                                --------------  ---------------  ------------- 
 

Nuformix plc

Unaudited Interim Results

Notes to the Consolidated Financial Statements for the six months ended 30 September 2021

1. Basis of preparation of interim financial information

The consolidated interim financial statements have been prepared in accordance with the recognition and measurement principles of International Accounting Standards as endorsed by the UK Endorsement Board ("IAS").

On 31 December 2020, IFRS as adopted by the European Union at that date was brought into UK law and became UK-adopted International Accounting Standards, with future changes being subject to endorsement by the UK Endorsement Board. The Group transitioned to UK-adopted International Accounting Standards in its consolidated financial statements on 1 April 2021. Whilst this change constitutes a change in accounting framework, there is no impact on recognition, measurement or disclosure.

The consolidated interim financial statements are unaudited and do not constitute statutory accounts within the meaning of Section 434 of the Companies Act 2006. Statutory accounts for the year ended 31 March 2021, prepared in accordance with IAS, have been filed with the Registrar of Companies. The Auditors' Report on these accounts was unqualified and included a reference to which the Auditors drew attention by way of an emphasis of matter, without qualifying their report, that a material uncertainty existed that might cast significant doubt on the Group's ability to continue as a going concern at that time. The Auditors' Report did not contain any statements under section 498 of the Companies Act 2006.

The consolidated interim financial statements are for the 6 months to 30 September 2021.

The consolidated interim financial information does not include all the information and disclosures required in the annual financial statements, and should be read in conjunction with the group's annual financial statements for the year ended 31 March 2021, which were prepared in accordance with IFRS as adopted by the European Union. As explained above, although this was a different accounting framework, there is no impact on recognition, measurement or disclosure.

2. Basis of consolidation

On 16 October 2017 the Company acquired the entire issued ordinary share capital of Nuformix Technologies Limited and became the legal parent of Nuformix Technologies Limited. The accounting policy adopted by the Directors applies the principles of IFRS 3 (Revised) "Business Combinations" in identifying the accounting parent as Nuformix Technologies Limited and the presentation of the Group consolidated statements of the Company (the legal parent) as a continuation of financial statements of the accounting parent or legal subsidiary (Nuformix Technologies Limited).

3. Going concern

The consolidated interim financial statements have been prepared on the going concern basis of preparation which, inter alia, is based on the directors' reasonable expectation that the Group has adequate resources to continue to operate as a going concern for at least twelve months from the date of their approval. In forming this assessment, the directors have prepared cashflow forecasts covering the period ending 31 March 2023 which take into account the likely run rate on overheads and research expenditure and the prudent expectations of income from its lead programmes.

Whilst there can be no guarantee of the successful outcome of future trials, in compiling the cashflow forecasts the directors have made cautious estimates of the likely outcome of such trials, when income might be generated and have considered alternative strategies should projected income be delayed or fail to materialise. These strategies include postponing non-committed research expenditure, securing alternative licensing arrangements from those currently planned and using the Group's established network for fundraising.

These circumstances indicate the existence of a material uncertainty which may cast significant doubt on the Group's ability to continue as a going concern. The consolidated interim financial statements do not include any adjustments that would result if the company or Group was unable to continue as a going concern.

After careful consideration, the directors consider that they have reasonable grounds to believe that the Group can be regarded as a going concern and, for this reason, they continue to adopt the going concern basis in preparing the consolidated interim financial statements.

4 Loss per Share

Loss per share is calculated by dividing the loss after tax attributable to the equity holders of the Group by the weighted average number of shares in issue during the period.

The basic earnings per share for each comparative period is calculated by dividing the loss in each of those periods by the legal entity's historical weighted average number of shares outstanding.

 
                                       30 September    30 September       31 March 
                                               2021            2020           2021 
                                          Unaudited       Unaudited        Audited 
                                                GBP             GBP            GBP 
Loss after tax                            (449,022)       (474,659)    (1,253,497) 
 
  Weighted average number of shares     591,609,368     490,145,083    580,629,372 
Basic and diluted loss per share              0.08p           0.10p          0.22p 
 
 
5. Property, Plant and 
 Equipment                     Leasehold      Computer     Laboratory 
                            improvements     equipment      equipment       Total 
                                     GBP           GBP            GBP         GBP 
Cost or valuation 
At 31 March 2020                 113,618        17,633         17,084     148,335 
Additions                              -           605              -         605 
                         ---------------  ------------  -------------  ---------- 
At 30 September 2020             113,618        18,238         17,084     148,940 
Disposals                      (113,618)      (16,677)       (17,084)   (147,379) 
                         ---------------  ------------  -------------  ---------- 
At 31 March 2021                       -         1,561              -       1,561 
At 30 September 2021                   -         1,561              -       1,561 
                         ---------------  ------------  -------------  ---------- 
 
  Depreciation 
At 31 March 2020                  42,950        12,751          9,722      65,423 
Charge                            15,521         2,145          1,190      18,856 
                         ---------------  ------------  -------------  ---------- 
At 30 September 2020              58,471        14,896         10,912      84,279 
Charge                            11,846           917            439      13,202 
Eliminated on disposal          (70,317)      (15,209)       (11,351)    (96,877) 
                         ---------------  ------------  -------------  ---------- 
 
  At 31 March 2021                     -           604              -         604 
Charge                                 -           259              -         259 
                         ---------------  ------------  -------------  ---------- 
At 30 September 2021                   -           863              -         863 
                         ---------------  ------------  -------------  ---------- 
 
  Carrying amount 
At 30 September 2020              55,147         3,342          6,172      64,661 
                         ===============  ============  =============  ========== 
 
  At 31 March 2021                     -           957              -         957 
                         ===============  ============  =============  ========== 
At 30 September 2021                   -           698              -         698 
                         ===============  ============  =============  ========== 
 
 
6. Intangible Assets 
                          Goodwill     Patents       Total 
                               GBP         GBP         GBP 
  Cost 
At 31 March 2020         4,023,484     449,611   4,473,095 
                       -----------  ----------  ---------- 
At 30 September 2020     4,023,484     449,611   4,473,095 
                       -----------  ----------  ---------- 
At 31 March 2021         4,023,484     449,611   4,473,095 
                       -----------  ----------  ---------- 
At 30 September 2021     4,023,484     449,611   4,473,095 
                       ===========  ==========  ========== 
 
Amortisation 
At 31 March 2020                 -     225,233     225,233 
Amortisation charge              -      22,481      22,481 
                       -----------  ----------  ---------- 
At 30 September 2020             -     247,714     247,714 
Amortisation charge              -      38,513      38,513 
                       -----------  ----------  ---------- 
At 31 March 2021                 -     286,227     286,227 
Amortisation charge              -      18,228      18,228 
                       -----------  ----------  ---------- 
At 30 September 2021             -     304,455     304,455 
                       ===========  ==========  ========== 
Net book value 
At 30 September 2020     4,023,484     201,897   4,225,381 
                       -----------  ----------  ---------- 
At 31 March 2021         4,023,484     163,384   4,186,868 
                       -----------  ----------  ---------- 
At 30 September 2021     4,023,484     145,156   4,168,640 
                       -----------  ----------  ---------- 
 

For impairment testing purposes, management consider the operations of the Group to represent a single cash-generating unit ("CGU") focused on research and development. Consequently, the goodwill is effectively allocated and considered for impairment against the business as a whole being the single CGU.

7. Share Capital

Allotted, called up and fully paid shares

 
                                   30 September                   30 September                                31 March 
                                           2021                           2020                                    2021 
                                      Unaudited                      Unaudited                                 Audited 
                              No.           GBP              No.           GBP              No.                GBP 
                  ---------------  ------------  ---------------  ------------  --------------------  ---------------- 
Ordinary shares 
 of GBP0.001 
 each               591,609,368     591,609        490,145,083     490,145        591,609,368          591,609 
                  ---------------  ------------  ---------------  ------------  --------------------  ---------------- 
 

8 Share Options and Warrants

The Group operates share-based payments arrangements to remunerate directors and key employees in the form of a share option scheme. Equity-settled share-based payments are measured at fair value (excluding the effect of non-market-based vesting conditions) at the date of grant. The fair value determined at the grant date of the equity-settled, share-based payments and is expensed on a straight-line basis over the vesting period, based on the Group's estimate of shares that will eventually vest and adjusted for the effect of non-market based vesting conditions.

Statement of Directors' Responsibilities

We confirm that to the best of our knowledge:

1. this interim condensed set of financial statements has been prepared in accordance with UK adopted IAS 34 'Interim Financial Reporting';

   2.    the interim management report includes a fair review of the information required by: 

2.1. DTR 4.2.7R of the Disclosure Guidance and Transparency Rules, being an indication of important events that have occurred during the first six months of the financial year and their impact on the condensed set of financial statements; and a description of the principal risks and uncertainties for the remaining six months of the year; and

2.2. DTR 4.2.8R of the Disclosure Guidance and Transparency Rules, being related party transactions that have taken place in the first six months of the current financial year and that have materially affected the financial position or performance of the entity during that period; and any changes in the related party transactions described in the last annual report that could do so.

The directors of Nuformix plc are listed in the Group's 2021 Annual Report and Accounts and the current board are set out on the Investors Information section of Nuformix's website at: Investors Information - Nuformix

Dr Alastair Riddell

Executive Chairman

Further copies of this document are available from the company's registered address and will be available on the company's website later today.

Nuformix plc

Registration number: 09632100

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(END) Dow Jones Newswires

December 14, 2021 02:00 ET (07:00 GMT)

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