FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Bluestone Jeffrey		 2. Issuer Name and Ticker or Trading Symbol

Provention Bio, Inc. [ PRVB ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__X__ Director                    _____ 10% Owner
_____ Officer (give title below)    _____ Other (specify below)
(Last)          (First)          (Middle)

C/O PROVENTION BIO, INC.,, P.O. BOX 666		 3. Date of Earliest Transaction (MM/DD/YYYY)

4/10/2020
(Street)

OLDWICK, NJ 08858
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
 6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock par value $0.0001 per share 4/10/2020  M  32246 A$2.36 39571 (1)I By the Bluestone Family Trust (2)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)		2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)		8. Price of Derivative Security
(Instr. 5)		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Employee Stock Option (right to buy) $2.36 2/27/2020  G (3)  V   128981   (4)3/27/2029 Common Stock 128981 $0 0 D  
Employee Stock Option (right to buy) $2.36 2/27/2020  G (3)  V 128981     (4)3/27/2029 Common Stock 128981 $0 0 I By the Bluestone Family Trust (2)
Employee Stock Option (right to buy) $2.36 4/10/2020  M     32246   (4)3/27/2029 Common Stock 32246 $0 96735 I By the Bluestone Family Trust (2)
Employee Stock Option (right to buy) $12.54 2/27/2020  G (5)  V   24000   (6)6/24/2029 Common Stock 24000 $0 0 D  
Employee Stock Option (right to buy) $12.54 2/27/2020  G (5)  V 24000     (6)6/24/2029 Common Stock 24000 $0 0 I By the Bluestone Family Trust (2)
Explanation of Responses:
(1) Includes 7,325 shares of common stock, par value $0.0001 per share (the "Common Stock") previously reported as being owned directly which are owned indirectly by the Bluestone Family Trust.
(2) The reporting person, together with his spouse are trustees and the reporting person, his spouse and children are the beneficiaries of the Bluestone Family Trust.
(3) On February 27, 2020, the reporting person contributed options to purchase up to 128,981 shares of Common Stock to the Bluestone Family Trust as a gift. The option was granted on March 27, 2019, pursuant to the Issuer's Amended and Restated 2017 Equity Incentive Plan.
(4) The option vests in eight equal semi-annual installments commencing on September 27, 2019 and will become fully vested on March 27, 2023.
(5) On February 27, 2020, the reporting person contributed options to purchase up to 24,000 shares of Common Stock to the Bluestone Family Trust as a gift. The option was granted on June 24, 2019, pursuant to the Issuer's Amended and Restated 2017 Equity Incentive Plan.
(6) The option fully vests on May 28, 2020.
Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Bluestone Jeffrey
C/O PROVENTION BIO, INC.,
P.O. BOX 666
OLDWICK, NJ 08858		X
Signatures
/s/ Andrew Drechsler as attorney-in-fact4/14/2020
**Signature of Reporting PersonDate
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