UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

NOTICE OF EFFECTIVENESS

Effective Date: September 16, 2013
Accession Number: 0001104659-13-069872
Submission Type: POS AM
CIK: 0001356857
Company Name: Trius Therapeutics Inc
File Number: 333-183673
Trius Therapeutics, Inc. (MM) (NASDAQ:TSRX)
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