CBF Cobra Bio-Man.

RNS Number:6197S
Cobra Bio-Manufacturing PLC
08 March 2007



Cobra Biomanufacturing Plc
(the "Company")

Holding in Company


TR-1: NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Identity of the issuer or the underlying issuer of existing shares to which
voting rights are attached:

Cobra Biomanufacturing Plc

2. Reason for the notification (please place an X inside the appropriate bracket
/s):

An acquisition or disposal of voting rights:                              ( )

An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached: ( )

An event changing the breakdown of voting rights:                         (X)

Other (please specify) :                                                  ( )
.................

3. Full name of person(s) subject to the notification obligation:

FMR Corp

4. Full name of shareholder(s) (if different from 3.):

See attached schedule

5. Date of the transaction (and date on which the threshold is crossed or
reached if different):

Revised due to DTR rules

6. Date on which issuer notified:

7 March 2007

7. Threshold(s) that is/are crossed or reached:

.................

8. Notified details:

A: Voting rights attached to shares

Class/type of shares if possible using    Situation previous to the Triggering
the ISIN CODE                             transaction
                                          Number of       Number of voting
                                          shares          Rights
ISIN                                      381,700         381,700
GB0031704835
Resulting situation after the triggering transaction

Class/type of shares if       Number of  Number of voting    % of voting
possible using the ISIN       shares     rights              rights
CODE
                              Direct     Direct   Indirect   Direct   Indirect
                                                   381,700               1.96%

B: Financial Instruments
Resulting situation after the triggering transaction

Type of      Expiration Exercise/     Number of voting rights that may   % of
financial    Date       Conversion    be acquired if the instrument is   voting
instrument              Period/       exercised/ converted.              rights
                        Date

Total (A+B)
Number of voting rights                      % of voting rights
                381,700                                    1.96%

9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable :

See attached schedule

Proxy Voting:

10. Name of the proxy holder:

FMR Corp

11. Number of voting rights proxy holder will cease to hold:

N/A

12. Date on which proxy holder will cease to hold voting rights:

N/A

13. Additional information:

As discussed with the FSA, prior to the implementation of the EU Transparency
Directive, we aggregated the interests of shares in FMR Corp (FMR) and Fidelity
International Limited (FIL) together for the purposes of shareholder reporting.
According to the new DTR rules we are now reporting the indirect holdings of FMR
and FIL separately. A separate notification is being submitted for FMR Corp.
Please note these holdings are correct as of close of business 05 March 2007.

14. Contact name:

Peter Coleman

15. Contact telephone number:

01782 714181

Schedule:

FIL

Issuer name: Cobra Biomanufacturing Plc

Current ownership percentage: 1.96%

Total shares held: 381,700

Issued share capital: 19,507,273

Shares held        Nominee                      Management Company
    381,700        Mellon Bank N.A              FMRCO

Fidelity International Limited (FIL) is the parent holding company for various
direct and indirect subsidiaries, including Fidelity Fund Management Limited
(FFML), Fidelity Investment Services Ltd (FISL), Fidelity Gestion (FIGEST),
Fidelity Investments Advisory (Korea) Limited, (FIAKL), Fidelity Investments
Management (Hong Kong) Limited (FIMHK), Fidelity Pension Management (FPM),
Fidelity Investments Japan (FIJ) and Fidelity Investments International (FII),
Investment managers for various non-US Investment companies and Institutional
clients.



                      This information is provided by RNS
            The company news service from the London Stock Exchange

END
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