TIDMIPO
RNS Number : 9919T
IP Group PLC
26 March 2019
FOR RELEASE ON 26 March 2019
("IP Group" or "the Group" or "the Company")
IP Group plc Annual Results Release
IP Group plc (LSE: IPO), the developer of intellectual
property-based businesses, today announces its annual financial
results for the year ended 31 December 2018.
Portfolio highlights
-- Fair value of portfolio: GBP1,128.2m (2017: GBP1,099.8m)
-- Net portfolio loss(1) of GBP48.4m (2017: gain of GBP94.2m)
-- Portfolio cash realisations: GBP29.5m (2017: GBP6.6m)
-- Capital provided by IP Group to portfolio companies and
projects: GBP100.9m (2017: GBP71.2m), with Parkwalk Advisors
investing a further GBP20.3m (2017: GBP13.4m)
-- Total funds raised by portfolio companies of GBP695m (2017: GBP315m)
-- Oxford Nanopore completed GBP100m financing round plus GBP50m
investment from NASDAQ-listed Amgen; significant commercial
progress
-- Ceres Power raised new capital of GBP74m from financial
investors, and new strategic partners Bosch and Weichai Power
-- Microbiotica signed microbiome collaboration with Genentech worth up to $534m
-- Avacta Group plc signed development alliance with LG Chem Life Sciences worth up to $310m
-- Artios Pharma completed GBP65m funding round
-- Ultrahaptics completed GBP35m funding round
-- IP Group Australasia completed its first two spin-out investments
Financial and operational highlights
-- Hard NAV(1) GBP1,217.5m (2017: GBP1,295.8m)
-- Net assets GBP1,218.2m (2017: GBP1,508.5m)
-- Gross cash and deposits GBP219.0m (2017: GBP326.3m)
-- Return on Hard NAV(1) of negative GBP75.6m (2017: positive GBP64.1m)
-- Loss for the year of GBP90.6m before exceptional goodwill
impairment(1) of GBP203.2m (2017: profit GBP53.4m; GBPnil)
-- Annual synergies achieved from Touchstone integration of GBP8m by full year 2020
-- US business attracted external funding from privately held US blue-chip family office
-- Appointment of Sir Douglas Flint as Chairman and Heejae Chae as Non-Executive Director
Post period end highlights
-- Featurespace completed GBP25.0m funding round
-- Technology Transfer Operations transferred back to Imperial
College; resulting in annual cost savings of c.GBP3m
[1] Alternative performance measure, see Note 27 for definition
and reconciliation to IFRS primary statements.
Alan Aubrey, Chief Executive of IP Group, said: "2018 has been a
year of consolidation for the Group as we finalised the integration
of Touchstone Innovations and identified significant cost synergies
that are now starting to come through. We remain excited by the
enlarged portfolio which we continue to believe will deliver
significant benefits for all stakeholders.
Material progress was made on a number of fronts in 2018,
notably the maturation of our model and portfolio with cash
realisations rising more than fourfold to GBP29.5m while our
portfolio companies raised GBP695m, more than double the prior
year. While market conditions for AIM-listed small-cap companies
were challenging, there was significant commercial progress among
many of the key companies in our portfolio, now valued at
GBP1.1bn.
We retain a high level of confidence in our portfolio, with many
of our companies due to reach material inflexion points this year,
and the benefits that will accrue sustainably to shareholders in
the years ahead.
For more information, please contact:
IP Group plc www.ipgroupplc.com
Alan Aubrey, Chief Executive
Officer +44 (0) 20 7444 0050
Greg Smith, Chief Financial
Officer +44 (0) 20 7444 0062/+44 (0) 7979
Liz Vaughan-Adams, Communications 853802
Charlotte Street Partners
David Gaffney +44 (0) 7854 609998
Andrew Wilson +44 (0) 7810 636995
Further information on IP Group is available on our website:
www.ipgroupplc.com
Notes
(i) Nature of announcement
This Annual Results Release was approved by the directors on 25
March 2019.
The financial information set out in this Annual Results Release
does not constitute the company's statutory accounts for 2018 or
2017. Statutory accounts for the years ended 31 December 2018 and
31 December 2017 have been reported on by the Independent Auditor.
The Independent Auditor's Reports on the Annual Report and
Financial Statements for 2018 and 2017 were unqualified, did not
draw attention to any matters by way of emphasis, and did not
contain a statement under 498(2) or 498(3) of the Companies Act
2006. Statutory accounts for the year ended 31 December 2017 have
been filed with the Registrar of Companies. The statutory accounts
for the year ended 31 December 2018 will be delivered to the
Registrar following the Company's annual general meeting.
The 2018 Annual Report and Accounts will be published in April
2019 and a copy will be posted on the Group's website
(www.ipgroupplc.com). In accordance with Listing Rule 9.6.1 a copy
of the Annual Report and Accounts will also be submitted to the
National Storage Mechanism on or around this date and will be
available for inspection at: www.Hemscott.com/nsm.do from that
time.
Throughout this Annual Results Release the Group's holdings in
portfolio companies reflect the undiluted beneficial equity
interest excluding debt, unless otherwise explicitly stated.
(ii) Forward looking statements
This Annual Report and Accounts may contain forward looking
statements. These statements reflect the Board's current view, are
subject to a number of material risks and uncertainties and could
change in the future. Factors which could cause or contribute to
such changes include, but are not limited to, the general economic
climate and market conditions, as well as specific factors relating
to the financial or commercial prospects or performance of
individual companies within the Group's portfolio.
STRATEGIC REPORT
Chairman's summary
2018 was a year of consolidation for IP Group as it bedded down
its acquisition of Touchstone Innovations plc ('Touchstone') and
navigated public investment markets that were not particularly
favourable towards smaller technology focussed companies, given
broader market uncertainties. Therefore, realisation opportunities
at valuations that made sense were limited, given the Group's
assessment of long-term potential. Encouragingly, our longer-term
valuation perspective was reinforced by a number of third-party
investments into and partnership collaborations across a number of
our most important portfolio companies during the year. Our
portfolio companies as a whole raised GBP695m, the highest annual
total so far. Alan Aubrey will cover these in more detail in his
report.
This is my inaugural report as Chairman of IP Group, having
taken over the role in November last year. I want to record on
behalf of shareholders and the Board our gratitude to my
predecessor, Mike Humphrey, for his commitment and wise counsel,
initially as a non-executive director upon joining the Board in
October 2011, before becoming Non-executive Chairman in March
2015.
Technology is reshaping the world at least as significantly as
the geopolitics which attracts so much media attention. This is
increasingly apparent in areas where technology leadership commands
global market dominance or has strategic implications. But it is
also the key to addressing some of the world's most pressing
challenges in disease prevention and mitigation, in the transition
to a less carbon intense energy world and in productivity
improvement. These are all core areas of focus within IP Group with
its focus on backing and building world-changing businesses, based
on innovative science and technology. This focus is enabled through
collaboration with the science and engineering departments of
leading universities in the UK, the United States and
Australasia.
By way of illustration of the impact of IP Group, with your
support, the Group has invested more than GBP850m to date in the UK
in science and technology and created more than 300 companies
which, in aggregate, have raised approximately GBP4.7bn of funding.
Through these endeavours, we calculate more than 5,000 jobs have
been created across the UK.
In addition, the Group's portfolio companies are, from the
outset, truly international in outlook, as technology has few
national boundaries, so projecting the 'Global Britain' positioning
that will be increasingly important to the UK's future trading
success.
One simple illustration of this in 2018 was the GBP7m investment
by portfolio company Ceres Power in a new, state of the art
manufacturing facility in Redhill in the UK, creating 60 new jobs
as demand, largely from overseas, for its low cost, next generation
fuel cell technology expanded. Alongside this, as part of a broader
strategic collaboration with Weichai Power, one of the leading
automobile and equipment manufacturing companies in China, Ceres
Power announced a joint venture for a major new fuel cell
manufacturing facility in Shandong, China, subject to completion of
successful trials.
Alan's operational review, which follows, highlights the other
key events during the year within the Group's portfolio.
Financial performance
The Group had a disappointing financial performance in 2018, the
most significant driver of which was share price declines of a
number of AIM listed portfolio companies. 2018 was the first year
for a long time that the world's major equity markets all declined,
with the FTSE100 down 12%, FTSEAIM down 19%, the S&P500 down
10% and NASDAQ down 8%. China's 'A' share market fell by 12%.
Given the long-term focus of the Group's business, management's
key financial performance indicator remains Hard NAV and this is
the core element of the incentive portion of directors'
remuneration, as approved by shareholders. At the end of 2018, Hard
NAV amounted to GBP1,217.5m, a reduction of 5.9% over the year,
with the fair value of the portfolio broadly flat at GBP1,128.2m
(2017: GBP1,099.8m). In terms of financial performance for the
year, the Group's Return on Hard NAV was negative GBP75.6m (2017:
positive GBP64.1m). It is important to recognise that, as the
Group's business model is long-term in nature, fluctuations in
portfolio company valuations and results are to be expected. The
Group ended the year with a strong balance sheet with gross cash
and deposits of GBP219.0m (2017: GBP326.3m).
The Board remains focused on actions that will bring the Group
into a more sustainable position and has taken steps to streamline
its operations following the Touchstone acquisition in late 2017.
Following modest headcount reductions and other combination
synergies, such as rationalising duplicated professional adviser
and similar costs during 2018, on 28 February 2019 we agreed to
transfer back to Imperial College their Technology Transfer
Operations. In this way we have reduced both cost and complexity in
the Group's business. We also began the process of slimming the
portfolio, disposing of a number of smaller investments.
Given these operational changes, the current macroeconomic
climate and the recent performance of the Group's portfolio,
considerable Board focus was directed to the carrying value of
goodwill on the Group's balance sheet, the significant majority of
which arose from the nil-premium, all-paper acquisition of
Touchstone and it was clear that this should be written off.
Although the resulting non-cash charge does not impact the Group's
key performance indicator of Hard NAV, which has always excluded
goodwill, this action resulted in an overall reported IFRS loss for
the year of GBP293.7m (2017: profit GBP53.4m). It is also worth
reiterating at this point that the strategic rationale for the
Touchstone acquisition, i.e. that of scale, liquidity and a more
balanced portfolio by sector and stage of development, remains
sound.
Governance and the Board
At Board level, there have been a number of changes this year in
addition to the departure of the previous Chairman, Mike Humphrey,
following his indication earlier in the year that he wished to
retire.
Sadly, we also said goodbye to Professor Lynn Gladden during
2018 following her appointment as Executive Chairman of the
Engineering and Physical Sciences Research Council (EPSRC) in
October. She left the Board at the end of September and I would
like to express on behalf of shareholders and the Board our thanks
to her for her dedicated service since joining the Board in
2014.
Heejae Chae, Chief Executive of AIM-listed Scapa Group plc, was
appointed as Non-executive Director in May. He brings to the Board
considerable experience both from the perspective as a CEO of
growing businesses and in finance, having spent the early part of
his career at The Blackstone Group and Credit Suisse First Boston.
Mr Chae has degrees in Economics and Engineering from Columbia
University and an MBA from Harvard University.
Our people
A key focus for the Board is recruitment and retention of the
talent needed to drive long-term sustainable success for the Group.
As we integrated Touchstone into the Group it reinforced the
imperative to create an environment of collaboration, co-operation
and collegiality, but also one that encourages challenge and
questioning, given the high degree of ambiguity and uncertainty
that surrounds the world of technology and life science
investment.
The culture we aim for at IP Group is necessarily
entrepreneurial while being collaborative, reflecting the Group's
purpose of evolving great ideas into world-changing businesses. As
we partner with academic institutions, it is critical that we have
a highly skilled workforce who can work constructively in
partnership to help foster the commercialisation of novel science.
IP Group's core values of being 'passionate, pioneering and
principled' guide the behaviours the Group wishes to see not only
in its general endeavours but also in its interactions with all
stakeholders. We believe that these values and behaviours have
contributed positively to the portfolio that we have built over
many years and we will be exploring how we refine and build on them
to deliver future success. I have been particularly impressed by
the quality and enthusiasm of IP Group's team and their
overwhelming ambition to make a difference to the world through
building the companies of the future.
Outlook
IP Group's portfolio is both well diversified and maturing and
we remain confident that it will deliver appropriate and meaningful
returns for stakeholders over the medium to long term. I would like
to thank our staff, academic partners and portfolio companies for
their commitment and contribution during the year as well as our
shareholders for their continued support.
Sir Douglas Flint
Chairman
Chief Executive's operational review
UK business
The results for the period, which showed a negative Return on
Hard NAV of GBP75.6m compared to a positive return of GBP64.1m for
2017, were impacted by the exposure of our quoted portfolio to the
weaker performance of stock markets as well as certain company
specific issues, the biggest of which was Diurnal. This financial
performance does not, we believe, reflect the underlying strength
and quality of IP Group's portfolio and overshadows the commercial
progress seen in the year from a number of our key assets which are
emerging as the leaders in their respective fields.
Turning first to Diurnal, its shares fell 78% over the year,
resulting in a GBP33.1m reduction in the value of our holding,
after its drug Chronocort did not meet the primary endpoint in a
Phase 3 study in congenital adrenal hyperplasia (CAH). IP Group has
invested a total of GBP19.4m into Diurnal to date and the company
is currently valued at GBP19.7m on AIM. Despite the headline
results, the company is optimistic that the drug remains
approvable, given some very positive outcomes using other measures
in the Phase 3 study, and that premium pricing is still possible.
You can read more in the life sciences report below.
Excluding Diurnal, the Group's quoted portfolio fell 35% in
2018, against a 19% decline in the performance of the AIM index
which has suffered this year from a number of well-documented
factors. Including Diurnal, the Group's quoted portfolio fell 43%
during 2018. Of the bigger quoted share price falls were Xeros
Technology Group (GBP21.1m loss), Circassia (GBP14m loss) and
Mirriad Advertising (GBP12.3m loss), in addition to a GBP12.4m loss
for private company Cell Medica Limited. These falls more than
offset fair value gains, the largest of which came from Garrison
Technology (GBP15.2m gain), Ceres Power (GBP11.1m gain), Uniformity
Labs (GBP9.0m gain) and Featurespace (GBP9.6m gain).
I am also pleased to report that there was strong commercial
progress in the year from a number of our portfolio companies.
Oxford Nanopore Technologies, Ceres Power and WaveOptics have all
signed partnerships with blue chip companies further validating
their respective technologies. In particular, Ceres Power signed
agreements with China's Weichai Power and Germany's Robert Bosch.
In the private portfolio, NASDAQ-listed Amgen invested GBP50m into
Oxford Nanopore Technologies while WaveOptics agreed a partnership
with and investment from Goertek, a global leader in the design and
manufacturing of high-tech consumer electronics.
In the quoted portfolio, there was excellent commercial progress
from a number of companies that, in our opinion, has not yet been
reflected in their share prices. Tissue Regenix (GBP4.6m loss)
announced that its subsidiary CellRight Technologies entered into
an agreement to allow Arthrex, Inc. to distribute its proprietary
'BioRinse' bone portfolio throughout Europe, with the initial focus
on the UK. Avacta Group (GBP5m loss) signed a development alliance
with LG Chem Life Sciences worth up to $310m including $180m across
upfront, near-term payments and development milestones. Medaphor,
which has changed its name to Intelligent Ultrasound Group plc, is
expecting turnover for 2018 to increase by approximately 27% to
between GBP5.3m and GBP5.4m.
Touchstone integration
From an operational perspective, in 2018 one of the most
significant areas of focus for the Group was finalising the
integration of the Touchstone team and portfolio, which I am
pleased to report is now substantially complete.
The former Touchstone and IP Group portfolio companies are being
managed together in the UK by our Life Sciences and Technology
partnerships that were formed in the year from a combination of
professionals from both businesses. While there has been a level of
further reduction in the fair values of some of the former
Touchstone companies, the combined portfolio is now well-balanced
by sector and stage of development and contains a number of
opportunities for significant future value growth.
While the strategic rationale of the transaction was primarily
one of scale and combined portfolio strength, it also presented the
opportunity to realise synergies from an operational perspective.
During the 18 months since the transaction completed, we have taken
a number of steps to streamline the two businesses. Most recently,
in the first quarter of 2019, we agreed to transfer back to
Imperial College the technology transfer operation known previously
as Imperial Innovations. This will not impact our plans to continue
to work with Imperial and continue to invest in some of the most
exciting opportunities from the university.
There has been some modest headcount reduction, outside of the
transfer of the technology transfer team to Imperial College. We
have taken the opportunity to rationalise professional fees and
other administrative costs, particularly for services duplicated
across the two businesses, including the costs of Touchstone being
a listed entity. Finally, in March 2019, we surrendered the lease
on Touchstone's former head office in Central London. As a result
of these actions, we anticipate annual cost synergies by full-year
2020 of more than GBP8m from the combination versus the
pre-integration cost base of the two companies.
North America
Turning to North America, IP Group, Inc. and its portfolio
companies continued to make significant developments during the
12-month period. The portfolio attracted $30m of external
investment from both financial and strategic investors and reached
several significant milestones. These financing rounds resulted in
net portfolio gains in the US portfolio of $14m during the year,
representing an increase of approximately 50% on the opening
position. The team also attracted a significant strategic
investment into the US business that was led by a privately held
blue-chip family office based in the US. We consider these
co-investments to be a great endorsement of both our model and
attractiveness of the portfolio and future opportunities to US
investors.
Of particular note in the portfolio, Exyn Technologies
(University of Pennsylvania) completed a series of global
commercial engagements, the most recent with Dundee Precious Metals
(TMX:DPM), a Canadian-based international mining company, that we
believe significantly endorse Exyn's ground-breaking artificial
intelligence technology and its commercial relevance. Carisma
Therapeutics (University of Pennsylvania), a developer of
technology that targets and kills solid tumours, closed a $53.0m
Series A financing round led by AbbVie Ventures and Healthcap.
Uniformity Labs (Princeton University) has made substantial
progress establishing relationships with new customers, including
multiple validation projects and a signed letter of intent for the
supply of aluminium powder.
We added Yale University as a collaboration partner, bringing
our total to six prominent universities and three U.S. Department
of Energy Labs. We have an established team of 16 professionals
with broad business development capabilities across life sciences
and technology who continue to advance the existing portfolio of 21
exciting companies.
Australasia
In Australasia, the Group completed its first two investments
from partner universities in 2018, Canopus Networks (The University
of New South Wales) and Inosi Therapeutics (Monash University).
Canopus is using machine learning and software-defined networking
to develop solutions for analysing and optimising data flows within
telecommunication networks and large corporates. Inosi is
developing small-molecule inhibitors of a novel target for
fibrosis-related diseases and the Group invested alongside
BioCurate, a joint venture of Monash and Melbourne universities for
early stage commercialisation of pharmaceutical research.
On the capital side, the Group continued to work with Hostplus,
one of Australia's largest superannuation funds with over AU$34
billion in funds under management, through the AU$100m IP Group
Hostplus Innovation Fund which participated in financings for
Oxford Nanopore Technologies and Ultrahaptics in 2018.
Our team in Australasia now totals nine, based between
Melbourne, Sydney and Brisbane, and represents a strong blend of
expertise and experience in academia, industry and
commercialisation. In addition, the Group has established a
steering group in Australasia comprising experienced senior
executives with a broad range of operational and investment
experience. The team has identified an attractive pipeline of
opportunities and anticipates progressing several of these to
investment in 2019.
Greater China
Many of our portfolio companies have secured investment and
business partnerships in China, including Oxford Nanopore, Ceres
Power, Mirriad Advertising and Creavo Medical Technologies. The
Group considers China to be strategically important and, in
September, announced the launch of its office in Hong Kong in order
to continue to facilitate market entry, business partnership and
investment discussions with relevant Chinese partners for our
portfolio companies. This also allows the Group to manage its
growing pan-Asian investor base. Following last year's success in
Beijing and Shenzhen, the Group hosted its second annual "Global
Deep Tech Forum" event in Hong Kong and Shanghai in September where
22 of our portfolio companies introduced their technology and
business to hundreds of attendees from the Greater China area.
Outlook
In summary, significant progress was achieved by many of our
portfolio companies during 2018, which in our view is yet to be
reflected in their valuations. As a result, the Board is confident
about the potential of the Group's portfolio including Oxford
Nanopore, which commented publicly on significant increases in its
order book and has attracted investment from a world-leader in
human genetics, First Light Fusion Limited, which aims to
demonstrate fusion using its 'Machine 3' by mid-2019 and a number
of our therapeutic assets which are approaching key inflexion
points.
While IP Group is a long-term business where results can and do
fluctuate from year to year, the Board is confident that the
portfolio can generate significant returns for stakeholders and in
the medium term will begin to position the business for transition
to a more self-sustaining model. This will allow the Group to
sustainably fulfil its mission of supporting outstanding science
from around the world from the eureka moment through to
maturity.
Alan Aubrey
Chief Executive Officer
Portfolio review
Overview
At 31 December 2018 the value of the Group's portfolio had
increased to GBP1,128.2m, from GBP1,099.8m at the end of 2017, as a
result of the fair value movements set out below, and a net
investment of GBP71.4m (2017 GBP64.6m). The portfolio now consists
of interests in 147 companies (122 UK, 23 US and 2 Australasia, and
61 of which are of key focus), strategic holdings in three
multi-sector platform businesses as well as a further 44 de minimis
holdings and 47 organic holdings (2017: 155,3,42,39).
In a departure from previous years, we have categorised the
portfolio to highlight those companies on which the life science
and tech partnership teams focus a significant proportion of their
resources and capital. These 61 companies comprise 84% of the
portfolio by value. Outside these companies, the portfolio contains
a broad selection of potentially exciting opportunities, many of
which are at an early stage, but which typically receive a lower
level of management resource and capital.
During the year to 31 December 2018, the Group provided
pre-seed, seed and post-seed capital totalling GBP100.9m to its
portfolio companies (2017: GBP71.2m). The Group deployed capital
into nine new companies or projects during the year (2017: 21),
five of which were sourced from the UK, two from the US and two
from Australasia (2017: 10,11,0). The three geographies have
provided consistent pipelines of opportunities, and the Group has
backed the best innovations from all three, whilst sustainably
managing portfolio size. The new investments in Australasia have
helped to further diversify the portfolio geographically and are a
reflection of the quality of new research the Group now has access
to through the additional university partnerships it formed in
2017.
In 2018 we fully exited three investments (2017: two), and a
further 15 companies, with a total historic cost of GBP8.5m, were
closed or fully provided against (2017: two, GBP2.9m).
During 2018 the cash proceeds from the realisation of
investments increased to GBP29.5m (2017: GBP6.6m), arising from 14
investments, spread roughly evenly across the sectors and
comprising a mix of quoted and private capital. The largest
disposals were from interests in Veryan Medical Limited, Abzena
plc, Getech Group plc and Concirrus Limited. The largest
realisations in the prior year arose from the cash received from
the sales of Puridify Limited and Plaxica Limited.
Performance summary
A summary of the Income Statement gains and losses which are
directly attributable to the portfolio is as follows:
2018 2017
GBPm GBPm
---------------------------------------------------- ------- ------
Unrealised gains on the revaluation of investments 99.7 99.3
Unrealised losses on the revaluation of investments (153.1) (49.2)
Effects of movement in exchange rates 3.0 (1.1)
---------------------------------------------------- ------- ------
Change in fair value of equity and debt investments (50.4) 49.0
---------------------------------------------------- ------- ------
Gain on disposals of equity investments 2.0 0.1
Gain on deconsolidation of subsidiary - 45.1
---------------------------------------------------- ------- ------
Net portfolio gains/(losses) (48.4) 94.2
---------------------------------------------------- ------- ------
The most significant contributors to unrealised gains on the
revaluation of investments were Garrison Technology Limited
(GBP15.2m), Ceres Power Holdings plc (GBP11.1), Featurespace
Limited (GBP9.6m), Uniformity Labs Inc (GBP9.0m), Wave Optics
Limited (GBP7.6m) and Ultrahaptics Holdings Limited (GBP6.4m)(1)
.
The major contributors to the unrealised losses on the
revaluation of investments were Diurnal Group plc (GBP33.1m), Xeros
Technology Group plc (GBP21.1m), Circassia Pharmaceuticals plc
(GBP14.0m), Cell Medica Limited (GBP12.4m), Mirriad Advertising plc
(GBP12.3m), Actual Experience plc (GBP8.4m), OxSyBio Limited(1)
(6.6m), Abzena plc (GBP5.2m) and Avacta Group plc (GBP5.0m).
The performance of the Group's holdings in companies quoted on
AIM saw a net unrealised fair value decrease of GBP99.8m (2017:
decrease of GBP1.0m) while the Group's holdings in unquoted
companies experienced a net fair value increase of GBP46.4m (2017:
increase of GBP49.9m, in addition to a GBP45.1m gain in respect of
the deconsolidation of Istesso Limited and its recognition as a
portfolio company).
Investments and realisations
The Group's overall rate of capital deployment increased during
2018, with a total of GBP100.9m being deployed across 77 new and
existing projects (2017: GBP71.2m, 79 projects). The average level
of capital deployed per company remained relatively consistent, at
GBP1.3m, compared to GBP1.2m in 2017.
Cash invested by company focus was as follows:
2018 2017
GBPm GBPm
------------------------------------------------------ ------ -----
Top 20 26.0 20.7
Focus 41.6 23.7
Other (including companies exited by 31 December 2018) 19.4 20.7
------------------------------------------------------ ------ -----
Total United Kingdom 87.0 65.1
United States(2) 13.2 6.1
Australasia 0.7 -
Multi-sector platforms - -
------------------------------------------------------ ------ -----
Total purchase of equity and debt investments 100.9 71.2
------------------------------------------------------ ------ -----
Less cash proceeds from sales of equity investments (29.5) (6.6)
------------------------------------------------------ ------ -----
Net investment 71.4 64.6
------------------------------------------------------ ------ -----
(2) United States investment total includes GBP1.1m invested in
Uniformity Labs, Inc., which is one of the Top 20 holdings by
value.
During the year, 9 opportunities received initial incubation or
seed funding (2017: 21).
(1) Of the fair value gains noted above, the following amounts
are attributable to the third-party limited partners in the
consolidated fund, IPVF II: Ultrahaptics Holdings Limited: gain of
GBP1.8m (2017, GBP2.0m), OxSyBio Limited: loss of GBP1.3m (2017:
gain of GBP0.7m).
Portfolio analysis by focus
At 31 December 2018, the Group's portfolio fair value of
GBP1,128.2m was distributed across the portfolio as follows:
As at 31 December 2018 As at 31 December 2017
Fair value Number Fair value(2) Number
---------------- ---------- ----------------- ---------
Stage GBPm % % GBPm % %
--------- ----- ---- ---- ---------- ----- --- ----
Top 20 by value 732.5 68% 20 13% 663.0 62% 20 13%
Focus 204.4 19% 41 27% 216.8 20% 41 26%
Other 147.7 13% 89 60% 190.5 18% 97 61%
---------------------- --------- ----- ---- ---- ---------- ----- --- ----
Total 1,084.6 100% 150 100% 1,070.3 100% 158 100%
De minimis & Organic
holdings 8.3 7.2
---------------------- --------- ----------
Total Portfolio 1,092.9 1,077.5
---------------------- --------- ----------
Attributable to third
parties(1) 35.3 22.3
---------------------- --------- ----------
Gross Portfolio 1,128.2 1,099.8
---------------------- --------- ----------
(1) The amount attributable to third parties consists of
GBP18.7m attributable to minority interests represented by third
party limited partners in the consolidated fund, IPVFII, GBP5.5m
attributable to minority interests represented by third party
limited partners in the consolidated US portfolio, GBP8.1m
attributable to Imperial College London and GBP3.0m to other third
parties (2017: GBP16.3m IPVFII, n/a US, GBP5.7m Imperial College,
GBP0.3m other).
(2.) Restated following finalisation of provisional acquisition
accounting in respect of Touchstone acquisition (see note 26)
Top 20 investments consist of 20 most valuable holdings in the
Group's portfolio by year-end value. Focus investments are those
investments that are not within the 20 most valuable but on which
the life sciences and technology teams focus a significant
proportion of their resources and capital. These investments
typically, although not exclusively, fall within the 100 most
valuable portfolio company holdings by year-end value. Other
companies are those that are not within the Top 20 or focus
category.
Companies which are at a very early stage or in which the
Group's holding is of minimal value, but remain as operating
businesses, are classed as de minimis holdings. Organic holdings
are investments in which the Group has acquired a shareholding upon
creating the company as a result of our technology transfer
relationship with Imperial College London, but in which we have not
actively invested.
The total value of the Group's 147 portfolio companies
(excluding multi-sector platforms, organic investments and de
minimis holdings), calculated by reference to the Group's holding
in such companies and grossed up to reflect their total value, is
now in excess of GBP5bn, or almost GBP6bn including the Group's
holdings in multi-sector platform companies, most significantly
Oxford Sciences Innovation plc (2017: GBP4bn, GBP5bn).
Portfolio analysis by sector
The Group funds spin-out companies based on a wide variety of
scientific research emerging from leading research-intensive
institutions and does not limit itself to funding companies from
particular areas of science. The Group splits its core opportunity
evaluation, investment and business building team into two
specialist divisions, Life Sciences and Technology. Where the Group
invests in businesses that cannot be classified within these
divisions, primarily those portfolio companies which also invest in
other opportunities, they are recorded as multi-sector platforms.
An update on the two primary operating segments is included in the
financial review.
As at 31 December 2018 As at 31 December 2017
Fair value Number Fair value(2) Number
---------------- ---------- ----------------- ---------
Sector GBPm % % GBPm % %
Life Sciences 624.5 57% 64 43% 680.1 63% 73 46%
Technology 396.9 37% 83 55% 327.3 31% 82 52%
Multi-sector platforms 63.2 6% 3 2% 62.9 6% 3 2%
Total 1,084.6 100% 150 100% 1,070.3 100% 158 100%
De minimis & Organic
holdings 8.3 7.2
----------------------- --------- ----------
Total Portfolio 1,092.9 1,077.5
----------------------- --------- ----------
Attributable to third
parties(1) 35.3 22.3
----------------------- --------- ----------
Gross Portfolio 1,128.2 1,099.8
----------------------- --------- ----------
1. The amount attributable to third parties consists of GBP18.7m
attributable to minority interests represented by third party
limited partners in the consolidated fund, IPVFII, GBP5.5m
attributable to minority interests represented by third party
limited partners in the consolidated US portfolio, GBP8.1m
attributable to Imperial College London and GBP3.0m to other third
parties (2017: GBP16.3m, GBP0.0m GBP5.7m, GBP0.3m).
2. Restated following finalisation of provisional acquisition
accounting in respect of Touchstone acquisition (see note 26)
The following table lists the value movements attributable to
the largest twenty portfolio investments by value, which represent
62.8% of the total portfolio value (2017: 69.0%). Additional detail
on the performance of these companies is included in the Life
Sciences and Technology portfolio reviews.
Fair value Fair value Fair value
Group of Group movement of Group
holding holding
stake at Net and fees at
Sector, Quoted at 31 settled
(Q)/ Dec 31 Dec investment/ in 31 Dec
Unquoted
(U) 2018(1) 2017(2) (divestment) equity 2018
Company name Description % % GBPm GBPm GBPm GBPm
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Enabling the
analysis
of any living
Oxford Nanopore thing,
Technologies by any person, in Life Sciences
Limited any environment (U) 18.2% 274.1 - - 274.1
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Design and
development
of novel
therapeutic Life Sciences
Istesso Limited drugs (U) 59.1% 51.1 2.0 4.8 57.9
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
University of
Oxford
preferred IP
partner
Oxford Sciences under 15-year Multi-sector
Innovation framework platforms
plc agreement (U) 7.6% 55.5 - - 55.5
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
World leading
developer
of next generation
Ceres Power fuel cell Technology
Holdings plc technology (Q) 18.9% 31.5 4.4 11.2 47.1
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Anti-malware
solutions
for enterprise
Garrison Technology cyber Technology
Limited defences (U) 23.4% 9.8 3.8 15.2 28.8
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Contactless haptic
technology
Ultrahaptics "feeling Technology
Holdings Limited without touching" (U) 23.8% 21.8 0.5 5.2 27.5
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Developing high
Autifony value,
Therapeutics novel medicines to Life Sciences
Limited treat CNS diseases (U) 28.2% 23.9 - 1.7 25.6
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Featurespace Leading predictive Technology
Limited analytics company (U) 25.4% 15.6 - 9.6 25.2
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
PsiOxus Oncolytic viral
Therapeutics therapeutics Life Sciences
Limited for cancer (U) 25.0% 22.7 - - 22.7
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Optimising the
human
experience of
Actual Experience networked Technology
plc applications (Q) 22.1% 28.3 - (8.4) 19.9
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Clinical cancer
genomics
company utilising
circulating DNA
analysis
to improve testing
and treatment in Life Sciences
Inivata Limited oncology (U) 31.3% 12.8 6.0 - 18.8
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
New methodology for
achieving extreme
First Light intensity cavity Technology
Fusion Limited collapse (U) 35.9% 13.9 3.8 0.2 17.9
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Novel optical
waveguide
technology and
modules
for augmented
Wave Optics reality
Limited displays Technology(U) 21.1% 5.6 2.0 7.6 15.2
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Creavo Medical Quantum cardiac
Technologies imaging Life Sciences
Limited technology (U) 39.3% 14.4 - - 14.4
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Cell Medica T cell therapeutics Life Sciences
Limited for oncology (U) 24.6% 26.3 - (12.4) 13.9
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Online text-based
psychotherapy
Ieso Digital software Life Sciences
Health Limited and service (U) 45.5% 14.7 - (0.8) 13.9
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Cancer therapeutics
based on new
Mission understandings
Therapeutics of DNA damage Life Sciences
Limited response (U) 20.6% 12.4 - 1.3 13.7
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Mobile payments
with
Yoyo Wallet integrated loyalty Technology
Limited schemes (U) 40.0% 13.3 0.3 - 13.6
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Novel catalyst
technologies
to build carbon
dioxide
Econic Technologies into polyurethanes Technology
Limited and other polymers (U) 49.7% 10.6 3.0 - 13.6
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Equipment,
materials
and software for
Uniformity additive Technology
Labs Inc manufacturing (U) 22.8% 4.7 (0.6)(4) 9.0 13.1
------------------- ------------------- --------------- -------- ---------- ------------- ---------- ----------
Top 20 total 663.0 25.2 44.2 732.4
Other companies (130 companies) 407.3 38.8 (93.9) 352.2
De-minimis & Organic investments 7.2 2.5 (1.4) 8.3
Value not attributable to equity
holders 22.3 6.9 6.1 35.3(3)
---------------------------------------- --------------- -------- ---------- ------------- ---------- ----------
Total 1,099.8 73.4 (45.0) 1,128.2
--------------------------------------------------------- -------- ---------- ------------- ---------- ----------
1. Represents the Group's undiluted beneficial economic equity
interest (excluding debt), including the Group's portion of IPVFII,
and the Group's portion of the US portfolio. Voting interest is
below 50%.
2. 31 Dec 2017 fair value restated following finalisation of
provisional acquisition accounting in respect of Touchstone
acquisition (see note 26)
3. Includes GBP2.0m increase in revenue share to Imperial
College London, with a corresponding increase in revenue share
liability resulting in no net fair value movement.
4. The Group has not sold shares in Uniformity Labs Inc. during
the year. The realisation noted above reflects the effect of
minority ownership of the US portfolio, following the strategic
investment made during the year.
Portfolio review
LIFE SCIENCES
Dr Sam Williams Managing Partner, Life Sciences
IP Group's Life Sciences portfolio comprises 64 companies worth
GBP624.5m as at 31 December 2018
Review of the year
Oxford Nanopore
The Group's largest holding, Oxford Nanopore Technologies Ltd,
continues to make excellent progress with tangible signs of it
disrupting the $3.7bn DNA sequencing market. The company produces a
range of novel, proprietary, real-time DNA sequencing devices, from
small and portable formats such as MinION and Flongle to the
high-throughput PromethION, which can deliver sub-$1,000 genomes.
Oxford Nanopore's long-term goal is to enable the analysis of any
living thing, by any person, in any environment. Where sequencing
has traditionally been performed in the central lab environment,
the company seeks to address that central market but also open up
new, distributed markets. The Company made significant progress in
2018, as set out in further detail below, and this continued in
2019, including the announcement in March 2019 that its new 'R10'
nanopore had been released into early access. ONT also described
very promising internal results with R10, including consensus
accuracy of Q50 (or 99.999%).
Oxford Nanopore successfully completed a GBP100m fundraising in
March 2018, primarily from Asian investors, to support commercial
expansion and continued investment in R&D. It subsequently
announced a $50m investment from Amgen, whose subsidiary deCODE
Genetics noted that they have now used nanopore technology to
sequence several hundred genomes. While Oxford Nanopore has not yet
disclosed 2018 orders, it noted at the start of the year that it
was expecting strong growth across the world, with notable
contribution from China. In the previous year, between 2016-2017,
the Company approximately tripled its orders.
Key 2018 highlights for Oxford Nanopore included:
Technology
-- PromethION launch. PromethION is Oxford Nanopore's largest
device, designed to offer multi-Tb of sequence data, on demand.
Dramatic performance improvements during the year showing that a
PromethION could offer a 30X human genome for less than $600, and a
rapid pathway to less than $300 with larger data yields. By the end
of the year, researchers were routinely using PromethION to
sequence human genomes at scale.
-- Upgrades in nanopore, algorithms for enhanced performance.
The Company announced that a new nanopore, R10, will come online in
early 2019. Having delivered 'Q42' accuracy internally, and with a
pathway to Q50 (99.999%), this is expected to expand the
applications for which Oxford Nanopore can be used. The company is
also focused on updating its analysis algorithms and other
improvements that all contribute to ongoing performance
enhancements.
-- "RevD", a flow cell upgrade for high yields of data. This
release enabled as much as 30Gb of sequence data to be generated
from a single GridION/MinION Flow Cell, making these small devices
into powerful devices that can address an even broader range of
scientific questions.
-- Ultra-long reads. Oxford Nanopore technology sequences the
fragment of DNA/RNA that is presented to it, allowing very long
contiguous fragments to be analysed. This confers huge benefits
including easier assembly, characterisation of repeats and
structural variations and phasing. In 2018, the longest read ever
sequenced (2.3Mb) was revealed. This is symbolic of a broader
desire to get consistently high 'N50'; large numbers of long reads,
enabled by Oxford Nanopore's '109' kits also released in 2018.
-- Flongle. The adapter for MinION that allows low cost, rapid,
smaller tests, was released into an early access community in late
2018. With hugely disruptive potential in a range of testing
applications, 2019 will bring more examples of how it is being used
by the scientific community.
Applications
-- Whole human genomes: At the start of the year, Nature
Genetics published the first complete human genome using Oxford
Nanopore sequencing. Described as the most complete genome using a
single technology to date, the consortium of researchers, from nine
different institutions, added ultra-long reads to their assembly to
double their contiguity, estimate telomere lengths, and resolve
complex regions including the 4Mb major histocompatibility
complex.
-- Direct RNA: A landmark paper using nanopore sequencing for
the direct analysis of RNA was published in Nature in 2018. RNA
analysis accounts for about a third of the sequencing market; this
information gives scientists an insight into how DNA information is
really being expressed. Oxford Nanopore technology can uniquely
analyse RNA without using an intermediary (bisulfite sequencing),
giving new biological insights including methylation profiling.
-- Towards diagnostics: Oxford Nanopore technology is currently
for research use only, however scientists are exploring ways to use
it in a regulated environment to provide diagnostic testing. During
the year, researchers showed methods for rapid characterisation of
lung infections in an acute setting, TB in remote populations,
rapid characterisation of acute myeloid leukemia, and rapid testing
of Huntingdon's disease. These applications are expected to
progress towards clinical use in 2019.
-- Public health: Real time, portable sequencing is uniquely
positioned to be used in the field rather in the lab, for rapid
insights. In 2018, Oxford Nanopore's technology was used in real
time surveillance of outbreaks of Rabies, Lassa fever, Yellow
Fever, Flu, Dengue, Malaria, E. coli and MRSA.
-- Plant genomes: Understanding plant genomes is important for
agriculture and food industries, however plant genomes are
typically very large and complex; the abundant long read sequencing
of Oxford Nanopore is uniquely positioned to address this. In 2018,
researchers spoke about using nanopore to sequence many plant
species, including '100 tomato genomes in 100 days'.
-- Targeted sequencing: Oxford Nanopore has indicated that in
2019 it will expand the availability of its technology in targeted
sequencing, which is used in a broad range of application
areas.
For more information about the uses of nanopore technology,
visit https://nanoporetech.com/resource-centre
Other significant portfolio company updates
The overall performance of the rest of the life sciences
portfolio has been poor (-10.4%), largely as a result of negative
share-price movement in the listed companies. Most notably, Diurnal
Group plc suffered a setback when its drug Chronocort did not meet
the primary endpoint in a Phase 3 study in congenital adrenal
hyperplasia (CAH). The stock closed the year down 85.5%, marking a
GBP33.1m reduction in our fair value holding. However, despite
this, we and the company are optimistic that the drug remains
approvable, given some very positive outcomes using other measures
in the Phase 3 study, and that premium pricing is still possible.
Diurnal is due to receive advice from the EMA in the first half of
2019 which will provide an indication of the way forward. Assuming
a positive outcome, the company anticipates filing a Marketing
Authorisation Application (MAA) for Chronocort(R) in Q4 2019.
Other poor performers in the portfolio were Circassia
(GBP14.0m), Avacta (GBP5.0m), Cell Medica (GBP12.4m), OxSyBio
(GBP6.6m) and Abzena which, despite being acquired for GBP34m by a
private equity buyer, provided a -GBP5.2m return for the year.
In the private Life Sciences portfolio, there were some notable
successes, including Microbiotica signing a $534m deal with
Genentech, Mission Therapeutics signing a collaboration with Abbvie
and Avacta signing a $310m deal with LG Group. From a financing
perspective, a number of our companies announced significant
funding rounds including Series B financings for Crescendo
Biologics (headline $70m raised), Artios Pharma (GBP65m raised) and
Inivata ($51.4m raised).
Portfolio review
TECHNOLOGY
Mark Reilly Managing Partner, Technology
IP Group's Technology portfolio comprises 83 companies worth
GBP396.9m as at 31 December 2018.
Review of the year
Technology
2018 saw strong revenue progress, major commercial deals, and
several large transactions in the Technology Partnership's
portfolio.
WaveOptics raised GBP20m from investors including Octopus, Bosch
and Goertek to further commercialise its waveguide technology,
which we believe will be one of the fundamental building blocks of
a huge emerging opportunity in augmented reality. The involvement
of Goertek in this transaction, whose customers include Samsung,
Sony and Google, is a major endorsement for the WaveOptics
technology and will enable the company to achieve mass market
manufacturing scale.
Another of our portfolio companies targeting the virtual and
augmented reality market, remote haptics pioneer Ultrahaptics,
capped off a year of progress by securing the Queens Award for
Enterprise and raising GBP35m from Mayfair Equity Partners,
Hostplus and Dolby Family Ventures. Another recipient of the Queens
Award, Featurespace, continued its impressive revenue growth in
2018, securing a place in the Sunday Times Tech Track 100, Deloitte
Technology Fast 50 and FT 1000 Fastest Growing Companies in Europe.
Featurespace announced that it had secured a new round of GBP25.0m
growth capital immediately after the year end. The round was led by
Insight Venture Partners, a New York-based global private equity
firm focused on high-growth investments in the technology sector,
while MissionOG, a US-based venture capital fund with significant
operational experience across the payments industry, also
participated in the round as a new investor. The funding was also
supported by existing investors including IP Group plc, Highland
Europe, TTV Capital, Robert Sansom and Invoke Capital.
One particularly notable element of these transactions is the
amount of money brought in from high-quality financial and
strategic investors who have never before invested in an IP Group
portfolio company. Between them, the Ceres Power, WaveOptics and
Ultrahaptics transactions brought in more than GBP75m from
high-quality first-time co-investors alongside circa GBP10m
invested by IP Group. This demonstrates the growing appeal of our
portfolio to a broader and deeper pool of capital.
We were also encouraged by the revenue progress at many of our
top assets, several of which are showing signs of progressing
maturity as revenue undergoes high double-digit or even
triple-digit growth. Examples include Ceres Power and Azuri, both
of which have a rapidly-growing revenue run rate that now exceeds
GBP10m per annum, and others such as Featurespace, Perpertuum and
Import.io which have all shown rapid recent revenue growth.
Unfortunately, the substantial fair value uplift delivered by
the above-mentioned transactions was significantly offset in the
year by negative movement in the price of some of our listed assets
in very challenging stock market conditions for small cap
technology companies. Xeros saw a large drop in price as the shares
reacted to slower than hoped-for commercial progress, but we were
also disappointed to see significant commercial progress at some
other assets contradicted by the share price. Actual Experience, in
particular, achieved major milestones in 2018 with its first
full-scale deployment of a large customer from one of its channel
partners, yet its share price reduced by 30% over the year. We hope
that these will prove short-term anomalies that will be rectified
as further progress occurs.
Cleantech
In our Cleantech portfolio we focus on building outstanding,
science-based businesses that mitigate the impacts of climate
change and other environmental challenges.
The IP Group Cleantech team continues to enhance its growing
reputation in both venture and policy-making circles. Our Head of
Cleantech, Dr Robert Trezona, is one of the handful of leaders from
the energy sector chosen to be a commissioner of the Energy
Transitions Commission (www.energy-transitions.org), which has been
working for over a year to develop a roadmap for how to reduce
carbon emissions from "hard to abate" sectors that must be
addressed by 2050 to avoid climate breakdown. The commission's
report was launched by Lord Adair Turner in November and vindicates
a number of technology themes we have been pursuing in the IP Group
Cleantech portfolio, notably fuel cells, carbon capture and
fusion.
The portfolio saw significant progress this year, most notably
at Ceres Power, which received new equity investment totalling
GBP74 million from financial investors and Bosch and Weichai Power.
The company announced in December that it had hit major milestones
with both of those two strategic partners, meaning that revenue for
their current 2017/18 financial year is expected to more than
double to approximately GBP15 million, from GBP7 million in
2016/17.
Elsewhere in the portfolio, carbon capture chemistry company
C-Capture announced a major partnership with Drax, the UK's biggest
power station, to deliver a Bioenergy Carbon Capture and Storage
(BECCS) pilot plant. If this project is successful, the C-Capture
technology could enable Drax to become the world's first
carbon-negative power station.
Finally, we were pleased to welcome a new company to the
Cleantech portfolio, University of Oxford spin-out and autonomous
vehicle software pioneer Oxbotica. Soon after our investment, the
company was among the lead recipients of a GBP25m grant supporting
the UK's first trials of self-driving vehicle services and has
already secured a strategic alliance with Addison Lee Group, the
global ground transportation business, to accelerate the
implementation of autonomous vehicles on London's streets.
Portfolio review
MULTI-SECTOR PLATFORMS
The Group has maintained its strategic stakes in its
multi-sector platform companies, most significantly Oxford Sciences
Innovation plc (OSI) and Cambridge Innovation Capital plc
(CIC).
As a result of its 15-year framework agreement with the
University of Oxford, OSI is the preferred intellectual property
partner for the provision of capital to, and development of, Oxford
spin-out companies and is entitled to 50 per cent of the
university's founder equity in spin-out companies. OSI has raised
in excess of GBP580m to date, and 2018 was another good year for
OSI as the portfolio continued to develop with a further 22
companies being added to the portfolio, and OSI leading on 33
investments. The number of investments now stands at 69 with a
total portfolio value of GBP229m and cash and deposits of GBP455m.
Net Asset Value per share has increased from 111.2p to 116.1p. In
early 2019, OSI announced the appointment of Patrick Pichette,
previously Google's Chief Financial Officer, as Chairman designate
and Charles Conn, most recently Chief Executive of the Rhodes
Trust, as Chief Executive.
CIC is a preferred investor for the University of Cambridge for
the commercialisation of intellectual property created at the
University under a 10-year memorandum of understanding, and a
Cambridge-based investor in technology and healthcare companies
from the Cambridge Cluster. CIC has raised GBP125.0m to date, and
in September 2018 CIC announced that it had committed a total of
GBP19.6m into two new and nine existing portfolio companies during
the period ending September 2018. By the end of 2018, CIC had
invested GBP111.0m since inception, in 24 companies.
Financial review
Greg Smith Chief Financial Officer
The Group recorded a loss for the year of GBP293.8m (2017:
profit of GBP53.4m) and a negative Return on Hard NAV, i.e. on the
Group's net assets excluding goodwill and intangible assets, of
GBP75.6m (2017: positive GBP64.1m). Net assets at 31 December 2018
were GBP1,218.2m (2017: GBP1,508.5m) and Hard NAV totalled
GBP1,217.5m at 31 December 2018 (2017: GBP1,295.8m), representing
115.0p per share (2017: 122.5p).
Consolidated statement of comprehensive income
A summary analysis of the Group's financial performance is
provided below:
2018 2017
GBPm GBPm
------------------------------------------------------------------ ------- ------
Net portfolio gains/(losses) (1) (48.4) 94.2
Change in fair value of limited and limited liability partnership
interests 2.3 (0.2)
Net Overheads (2) (26.0) (17.6)
Licensing income - Istesso group - 3.4
Administrative expenses - Istesso group - (3.5)
Administrative expenses - other consolidated portfolio companies (2.6) (2.1)
Administrative expenses - share based payments charge (1.9) (2.4)
IFRS3 charge in respect of acquisition of subsidiary (3.3) (4.4)
Carried interest plan release/(charge) 1.1 (1.3)
Amortisation of intangible assets (9.9) (3.9)
Goodwill impairment (203.2) -
Acquisition and restructuring costs - (9.1)
Net finance (expense)/income (1.8) 0.3
Taxation (0.1) -
------------------------------------------------------------------ ------- ------
(Loss)/profit for the year (293.8) 53.4
Other comprehensive income (0.1) -
------------------------------------------------------------------ ------- ------
Total comprehensive income/(loss) for the year (293.9) 53.4
------------------------------------------------------------------ ------- ------
Exclude:
Amortisation of intangible assets 9.9 3.9
Goodwill impairment 203.2 -
Share based payment charge 1.9 2.4
IFRS charge in respect of acquisition of subsidiary 3.3 4.4
------------------------------------------------------------------ ------- ------
Return on Hard NAV (75.6) 64.1
------------------------------------------------------------------ ------- ------
Exclude:
Acquisition and restructuring costs - 9.1
------------------------------------------------------------------ ------- ------
Return on Hard NAV excluding acquisition and restructuring
costs (75.6) 73.2
------------------------------------------------------------------ ------- ------
(1) Defined in Note 27 Alternative Performance Measures
(2) See net overheads table below and definition in Note 27
Alternative Performance Measures
Net portfolio gains/(losses) consist primarily of realised and
unrealised fair value gains and losses from the Group's equity and
debt holdings in spin-out businesses, which are analysed in detail
in the Portfolio review above.
Net Overheads
2018 2017
GBPm GBPm
-------------------------------------------------- ------ ------
Other income 9.9 6.1
Administrative expenses - all other expenses (34.5) (21.2)
Administrative expenses - Annual Incentive Scheme (1.4) (2.5)
Net Overheads (26.0) (17.6)
-------------------------------------------------- ------ ------
Other income totalled GBP9.9m; an increase on the year (2017:
GBP6.1m) due to the acquisition of Touchstone Innovation plc on
17(th) October 2017; the 2018 results see the consolidation on this
business for the full year. In addition, 2018 saw continued growth
in revenues for Parkwalk Advisors Limited, which was acquired on 31
January 2017. Other income comprises fund management fees,
licensing and patent income from Imperial Innovations, corporate
finance fees as well as consulting and similar fees, typically
chargeable to portfolio companies for services including executive
search and selection as well as legal and administrative
support.
Other central administrative expenses, excluding
performance-based staff incentives and share-based payments
charges, have increased to GBP34.5m during the period (2017:
GBP21.2m), primarily as a result of the annualised cost of
Touchstone Innovations plc, as well as the growth in IP Group's
Australasian operations. Of the GBP34.5m gross overheads, GBP5.8m
relates to the cost of the Group's US and Australasian operations.
The charge of GBP1.4m in respect of the Group's Annual Incentive
Scheme (2017: GBP2.5m), reflects performance against 2018 AIS
targets.
GBP3.3m of the Group's 2018 net overheads relate to the
Technology Transfer Office (2017: GBP0.7m). On 28 February 2019,
the Group transferred back the future commercialisation operations
of the TTO to Imperial, although retained its rights to future
earnings in respect of existing licenses. The transfer of the TTO
and the surrender of the lease on Touchstone Innovation's head
office in Central London (agreed on 22 March 2019), represent the
final steps in the conclusion of the Touchstone integration, that
management estimates will result in annual cost synergies of GBP8m
compared to IP Group and Touchstone's combined pre-acquisition net
operating cost base. The full level of annual synergies will be
realised following the completion of these last two integration
steps, i.e. for the year ending 31 December 2020 onwards.
Other income statement items
The share-based payments charge of GBP1.9m (2017: GBP2.4m)
reflects the accounting charge for the Group's Long-Term Incentive
Plan and Deferred Bonus Share Plan. This non-cash charge reflects
the fair value of services received from employees, measured by
reference to the fair value of the share-based payments at the date
of award, but has no net impact on the Group's total equity or net
assets.
In late 2017, the Group's drug development subsidiary, Istesso
Limited, was deconsolidated from the Group and recognised as a
portfolio company; its licensing income and administrating costs
are no longer consolidated into the Group's results.
Included within the Group's administrative expenses are costs in
respect of a small number of other portfolio companies. Typically,
the Group owns a non-controlling interest in its portfolio
companies; however in certain circumstances the Group takes a
controlling stake and hence consolidates the results of a portfolio
company into the Group's financial statements. The administrative
expenses included in the Group's results for such companies
primarily comprise staff costs, R&D and other operating
expenses.
The carried interest plan release of GBP0.8m (2017: charge of
GBP1.3m) relates to the recalculation of liabilities under the
Group's carry schemes, which include a newly constituted scheme for
the combined UK investment teams, as well as historic IP Group and
Touchstone schemes. No cash payments are due to scheme members
until sufficient asset realisations have occurred.
Costs of GBP3.3m (2017: GBP4.4m) were recognised in relation to
deferred and contingent consideration payable to the sellers of
Parkwalk Advisors Ltd deemed under IFRS3 to be a payment for
post-acquisition services.
Included in the Group's results are non-cash charges in respect
of the impairment of historic goodwill of GBP203.2m (2017: GBPnil)
and amortisation of acquisition intangibles of GBP9.9m (2017:
3.9m). The Group conducts impairment testing of goodwill on at
least an annual basis (or earlier if impairment triggers are
identified), using a consistent model to estimate the value in use
of the assets in each CGU versus the carrying value of goodwill.
Key inputs to the model include an estimate of the Group's future
portfolio return, the anticipated level of portfolio investment and
the Group's cost of capital. The rate of return estimate has
previously been based on the Group's long-term returns forecast,
which was supported by the Group's cumulative IRR performance. As a
result of current year portfolio performance, particularly the
Group's AIM-quoted companies, as well as the broader macroeconomic
and equity market environment, management has lowered its
assumptions for future rate of return for these purposes, using
historic cumulative IRR as a basis. This is the primary factor
resulting in the impairment of goodwill.
Acquisition intangibles relates to separately identifiable
assets recognised through the acquisition of Touchstone Innovations
plc, Parkwalk Advisors Limited and Fusion IP plc; these assets are
amortised over the period to which the contractual commitments
relate.
Statement of financial position
A summary analysis of the Group's assets and liabilities is
provided below:
Year ended Year ended
31 December 31 December
2018 2017
GBPm GBPm
------------------------------------- ------------ ------------
Goodwill and other intangible assets 0.7 212.7
Portfolio 1,128.2 1,099.8
Other non-current assets 18.8 12.6
Cash and deposits 219.0 326.3
EIB debt facility (97.8) (104.0)
Other net current liabilities (9.9) (11.4)
Other non-current liabilities (40.8) (27.5)
Total Equity or Net Assets 1,218.2 1,508.5
Exclude:
Goodwill (0.4) (202.5)
Other intangible assets (0.3) (10.2)
Hard NAV 1,217.5 1,295.8
-------------------------------------- ------------ ------------
Hard NAV per share 115.0p 122.5p
-------------------------------------- ------------ ------------
Goodwill and other intangible assets relate to the group's
previous acquisitions including Touchstone Innovations plc,
Parkwalk Advisors Limited, Fusion IP plc, Techtran Limited and Top
Technology Venture Limited.
The composition of, and movements in the Group's portfolio is
described in the Portfolio review above.
The majority of non-current assets relate to holdings in LP and
LLP funds; these include our co-investment fund IP Venture Fund, as
well as investments in Apollo Therapeutics LLP, UCL Technology Fund
LP and Technikos LLP. These funds give us both economic interest
and direct investment opportunities in a portfolio of early stage
companies, as well as relationships with high quality institutional
co-investors.
The largest item within other non-current liabilities are loans
from LPs of consolidated funds. The Group consolidates the assets
of two managed funds in which it has both a significant economic
interest, specifically co-investment fund IP Venture Fund II LP and
IPG Cayman LP, which was created during the year to facilitate
third party investment into the Group's US portfolio. Loans from
third parties of consolidated funds represent third party loans
into these partnerships. These loans are repayable only upon IPVFII
generating sufficient returns to repay the Limited Partners.
At 31 December 2018, the Group held gross cash and deposits of
GBP219.0m (2017: GBP326.3m). It remains the Group's policy to place
cash that is surplus to near-term working capital requirements on
short-term and overnight deposits with financial institutions that
meet the Group's treasury policy criteria or in low-risk treasury
funds rated "A" or above. The Group's treasury policy is described
in detail in note 2 to the Group financial statements alongside
details of the credit ratings of the Group's cash and deposit
counterparties.
At 31 December 2018, the Group had a total of GBP40.2m (2017:
GBP1.2m) held in US Dollars and GBP0.1m (2017: GBP0.1m) held in AUS
Dollars.
Both IP Group and Touchstone Innovation plc arranged debt
facilities with the European Investment Bank ("the EIB"), total
borrowings under which totalled GBP97.8m at the period end (2017:
GBP104m). Of these facilities, GBP15.4m is due to be repaid within
twelve months of the period end (2017: GBP6.3m). The facility
provides IP Group with an additional source of long-term capital to
support the development of the portfolio.
All-share acquisition of Touchstone Innovations plc
On 17 October 2017 the Group acquired control of 100% of the
ordinary shares in Touchstone Innovations plc. The Group has
recognised the assets and liabilities acquired in accordance with
IFRS 3 'Business Combinations'. Certain assets, primarily holdings
in unlisted portfolio companies that have been accounted for using
valuation techniques, were provisionally determined and for a
12-month period post-acquisition, adjustments are made to these
assets to the extent that new information is obtained about facts
and circumstances that were in existence at the acquisition date.
Post finalisation of the acquisition accounting, the prior year
Touchstone net assets acquired have been restated by GBP30.4m
(which comprises GBP30.8m portfolio valuation decrease, GBP0.4m
decrease in fixed assets and GBP0.8m decrease in non-current
liabilities) with a corresponding increase in goodwill.
Cash, cash equivalents and short-term deposits ("Cash")
The principal constituents of the movement in Cash during the
year are summarised as follows:
2018 2017
GBPm GBPm
------------------------------------------------------------- ------- ------
Net Cash generated/(used) by operating activities (24.9) (22.4)
Net Cash generated/(used) in investing activities (excluding
cash flows from deposits) (76.0) (67.6)
Cash acquired on acquisition of subsidiary undertakings
(net of cash acquired) - 107.8
Issue of share capital - 181.0
Repayment/drawdown of debt facility (6.3) 15.0
Effect of foreign exchange rate changes (0.1) 0.2
------------------------------------------------------------- ------- ------
Movement during period (107.3) 214.0
------------------------------------------------------------- ------- ------
At 31 December 2018, the Group's Cash totalled GBP219.0m, a
decrease of GBP107.3m from a total of GBP326.3m at 31 December 2017
due to net cash used by operating activities of GBP24.9m, net cash
used in investing activities of GBP76.0m and debt repayments of
GBP6.3m.
Taxation
The Group's business model seeks to deliver long-term value to
its stakeholders through the commercialisation of fundamental
research carried out at its partner universities. To date, this has
been largely achieved through the formation of, and provision of
services and development capital to, spin-out companies formed
around the output of such research. The Group primarily seeks to
generate capital gains from its holdings in spin-out companies over
the longer term but has historically made annual net operating
losses from its operations from a UK tax perspective. Capital gains
achieved by the Group would ordinarily be taxed upon realisation of
such holdings; however since the Group typically holds in excess of
10% in its portfolio companies and those companies are themselves
trading, the Directors continue to believe that the majority of its
holdings will qualify for the Substantial Shareholdings Exemption
("SSE"). This exemption provides that gains arising on the disposal
of qualifying holdings are not chargeable to UK corporation tax
and, as such, the Group has continued not to recognise a provision
for deferred taxation in respect of uplifts in value on those
equity holdings that meet the qualifying criteria. Gains arising on
sales of non-qualifying holdings would ordinarily give rise to
taxable profits for the Group, to the extent that these exceed the
Group's operating losses from time to time.
The majority of investments acquired via the combination with
Touchstone Innovations plc were previously held via Imperial
Innovation Sárl, which exempted dividends and gains from tax under
Luxembourg law provided the conditions for the relevant
participation exemption were met. During the year, the group
unwound this structure and as a result the assets of Touchstone
Innovations are now subject to the UK tax regime described
above.
The Group complies with relevant global initiatives including
the US Foreign Account Tax Compliance Act (FATCA) and the OECD
Common Reporting Standard.
Alternative Performance Measures ("APMs")
The Group discloses alternative performance measures, such as
Hard NAV and Return on Hard NAV, in this Annual Report. The
Directors believe that these APMs assist in providing additional
useful information on the underlying trends, performance and
position of the Group. Further information on APMs utilised in the
Group, is set out in note 27.
Risk management
Managing risk: our framework for balancing risk and reward
A robust and effective risk management framework is essential
for the Group to achieve its strategic objectives and to ensure
that the directors are able to manage the business in a sustainable
manner, which protects its employees, partners, shareholders and
other stakeholders. Ongoing consideration of, and regular updates
to, the policies intended to mitigate risk enable the effective
balancing of risk and reward.
Governance
Overall responsibility for the risk framework and definition of
risk appetite rests with the Board, who through regular review of
risks ensure that risk exposure is matched with an ability to
achieve the Group's strategic objectives. The IP Group Risk Council
operates to establish, recommend and maintain a fit for purpose
risk management framework appropriate for the Group and oversees
the effective application of the framework across the business.
Risk identification is carried out through bottom-up process via
operational risk registers maintained by individual teams, with
additional top-down input from the management team with
non-executive review being carried out by the audit and risk
committee.
Risk management process
Ranking of the Group's risks is carried out by combining the
financial, strategic, operational, reputational, regulatory and
employee impact of risks and the likelihood that they may occur.
Operational risks are collated into strategic risks which
identifies key themes and emerging risks and ultimately informs our
principal risks which are detailed in the Principal Risk and
Uncertainty section of this report. The operations of the Group,
and the implementation of its objectives and strategy, are subject
to a number of principal risks and uncertainties. Were more than
one of the risks to occur together, the overall impact on the Group
may be compounded.
The design and ongoing effectiveness of the key controls over
the Group's principal risks are documented using a 'risk and
control matrix', which includes an assessment of the design and
operating effectiveness of the controls in question. The key
controls over the Group's identified principal risks are reviewed
by management, the audit and risk committee and the Board at least
twice a year. However, the Group's risk management programme can
only provide reasonable, not absolute, assurance that principal
risks are managed to an acceptable level.
During 2018 we have continued to build on our existing risk
management framework, enhancing risk management and internal
control processes and established an outsourced internal audit
function with PwC. This activity included the development of
operational risk registers for new front line operations and a
refresh of existing front line and operational risk registers, an
assessment of the strategic risks and the appropriateness of our
principal risks, testing of key controls over our principal risks,
a review of protectionist policies across the globe that may impact
our investments internationally including proposed CFIUS laws in
the US and an updated Brexit risk review led by the Group's Risk
Council. We have continued to support the Board in exercising their
responsibility surrounding risk management through the Risk Council
who meet on a regular basis. Priorities for 2019 include embedding
the risk management culture further across the business,
integrating internal audit in the business and empowering control
owners to identify and react to risks as they happen through
regular risk reporting.
Brexit
The Group continues to closely monitor political developments as
the UK prepares to leave the EU in 2019. Management updated its
assessment of the impacts of Brexit on the Group in response to the
likelihood of a "No Deal" scenario increasing in 2018. PwC's
specialist trade team facilitated a Brexit workshop with key people
within IP Group across capital markets, finance, compliance,
operations, legal, talent management and human resources to i)
identify the key risks of the likely impacts of Brexit and ii) to
discuss actions the Group could take to mitigate the risks
identified. As a result of this work, management determined that
Brexit did not constitute a principal risk for the Group however
management produced guidance for portfolio company boards and the
Group's representatives to assist with their preparations. The key
risks impacting our strategic aims identified via the
above-mentioned process are detailed further below:
Key risks Actions taken
Macro-economic environment could cause Ø Reassurance provided to key
a short-term UK recession which would stakeholders and investors that tangible
reduce investor confidence and impact and measurable preparations are being
access to capital for both IP Group considered and made in order to mitigate
and its portfolio companies. any risks that Brexit poses as much
Access to capital: as possible for IP Group
Ø A No Deal Brexit would create Ø Diversification of co-investors
uncertainty in the short term, likely and funding has been undertaken over
translating to more restrictive financing recent years to mitigate the reliance
conditions. Any reduction in UK credit on UK co-funders of the Group and
worthiness due to a Brexit induced its portfolio companies.
increase in the current account deficit Ø Material contracts that the
and higher exposure outside the EU Group considered most likely impacted
could increase the cost of lending by the Brexit process were reviewed.
and decrease the availability of capital. It was concluded that there were no
Ø Significant parts of the Brexit clauses contained within these contracts
outcome and political declarations and no indications from the third
are still vague, continuing to exacerbate parties received that would indicate
the political and economic uncertainty. contracts such as EIB loan facilities
Subdued investor confidence across or fund management contracts would
the investment sector is highly likely be terminated.
regardless of a Deal/No Deal scenario.
This could impact access to capital
for both IP Group and its portfolio
companies.
Ø In both a No Deal and a Deal
scenario the UK will leave the EIB
which results in loss of access to
funding. While the Group has assumed
no further funding, changes to repayment
obligations of existing funding could
be initiated.
==================================================
The performance and management of Ø A portfolio company risk exposure
portfolio companies is crucial to and consultation plan was developed.
the success of the Group and, as a The Group surveyed the portfolio companies'
result, the preparation that portfolio representatives of a sample of the
company management teams have undertaken most mature companies to determine
to address key Brexit risks will be the common Brexit-related risks which
central to the successful navigation had been discussed at their board
of operational and other issues that meetings. This analysis determined
may impact their performance. that the key risks across this subsection
Performance and management of portfolio of the portfolio fell into the following
companies: five categories:
Ø The macro-economic impact of i. Hiring and retaining talent
a No Deal Brexit would lead to a significant ii. Supply chain difficulties including
GDP fall and the risk of a short-term tariffs, delays and additional cost
recession is high. IP Group's portfolio for storing extra stock
companies have significant exposure iii. Macro-economy and currency risk
to the UK economy. impacting profit
Ø The regulated nature of a number iv. Access to funding from investors
of the Group's portfolio companies and EU grants
across both sectors could mean that v. Regulatory changes
marketing pharmaceuticals and selling Ø The Group used this information
medical devices into the EU is no to prepare an advice note for all
longer possible in the current way portfolio company representatives
in the event of a No Deal Brexit. at IP Group to enable those individuals
to raise relevant issues at portfolio
company board levels.
Ø Additional advice was obtained
from advisors regarding clinical trials
sponsored in the UK, companies distributing
medicine into the EU and selling medical
devices into the EU.
==================================================
The macro-economic environment has Ø A employee engagement strategy
an impact on long-term recruitment was developed and communicated to
and planning for companies. Additional relevant employees at IP Group advising
visa restrictions will also impact of the latest advice from Government
academics and student movement to and confirming the Group's support
the UK thus affecting the pool for of those affected.
potential portfolio companies and Ø The Government's White Paper
the quality of university partnerships. on immigration was reviewed and concluded
People: that while no short term impacts are
Ø IP Group and its portfolio envisaged for current employees over
companies have current employees who the medium term the Group will need
do not hold a UK passport and are to closely monitor the proposed new
allowed to work in the UK based on immigration rules including salary
their European Citizenship. These thresholds for skilled migrants. The
employees are experiencing high levels proposals are subject to change and
of uncertainty and could be considering the Group will continue to monitor
alternative options for working in the impact of the final changes.
the UK.
Ø As a result of the Brexit vote
and ongoing political, economic and
academic uncertainty, the UK is considered
a less attractive job market on a
global scale. This will impact on
the Group and its portfolio companies
who depend on highly skilled and specialised
employees who are difficult to attract
and retain. Significant impact on
long-term recruitment is likely to
be impacted.
Ø Individuals within the field
of academia and students from overseas
may face uncertainty.
==================================================
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END
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