DiaMedica Founder Invited to Speak at International Scientific Conference
30 July 2009 - 11:53PM
Marketwired
DiaMedica Inc. (TSX VENTURE: DMA), a clinical stage
biopharmaceutical company developing novel treatments for various
stages of type 2 diabetes, is pleased to announce that Dr. Wayne
Lautt, co-founder of DiaMedica, will be speaking today at the
International Union of Physiological Sciences 36th World Congress,
a prestigious meeting held every four years, in Kyoto Japan.
Dr. Lautt's presentation, entitled "Meal-induced insulin
sensitization: role in the pathophysiology and prevention of
diabetes" will describe a nerve-signal mechanism that DiaMedica
believes is a fundamental cause of type 2 diabetes.
"This presentation affords the opportunity to describe a
mechanism that the Company believes is strongly connected to
insulin resistance, the precursor to type 2 diabetes, and to
present data that DiaMedica's approach fully reverses insulin
resistance in a diabetic animal model" stated Dr. Lautt.
"Furthermore, data will be presented demonstrating that restoring
this mechanism re-establishes the ability of the body to store more
nutrient energy in muscles, where it can be burned off, rather than
stored as fat, which leads to obesity."
About IUPS
The International Union of Physiological Sciences (IUPS) is an
organization which brings together physiologists from across the
globe. The unifying objective is to increase mankind's
understanding of the functions of cells, tissues, organs and organ
systems. It is an adhering member of the Council for International
Organizations of Medical Sciences and participates in the work of
several Scientific Committees of the International Council for
Science. The IUPS publishes a journal, Physiology in cooperation
with the American Physiological Society. The articles are
up-to-date reviews of modern physiology in order to maintain a
current knowledge of all fields of physiology.
About DiaMedica
DiaMedica is developing novel treatments for type 2 diabetes
based on a 'nerve signal' mechanism for which the Company has been
issued two U.S. patents. DiaMedica completed a successful phase II
trial with its lead product, DM-71, which demonstrated the ability
to reduce HbA1c (blood sugar) levels and weight in humans.
DiaMedica also completed a successful phase II trial with its
second compound, DM-83, designed to measure changes in insulin and
/ or glucose. The success of this clinical trial was highly
significant as DiaMedica believes it validated the novel 'nerve
signal' mechanism that would designate the Company's drugs as
first-in-class.
The Company's third drug in development, DM-99, recently
completed a phase II clinical trial. Patients receiving DM-99 in
Period 1 of this cross-over study showed a decrease in baseline
adjusted peak blood glucose concentration of 19% (p equals 0.077)
versus those receiving placebo as well as a decrease in incremental
glucose Area Under the Curve (AUC) 0-240 minutes of 31% (p equals
0.030) versus those receiving placebo. DM-199, a recombinant
version of DM-99, has been created with the expectation that it
will a long-acting version of DM-99. DiaMedica was recently awarded
a contribution of up to $492,000 from the National Research Council
of Canada Industrial Research Assistance Program (NRC-IRAP) to fund
the development of DM-199. DiaMedica has been recognized as one of
the Top Ten(TM) Life Science companies in Canada for the past two
years by the Ottawa Centre for Research and Innovation.
Caution Regarding Forward-Looking Information
Certain statements contained in this press release constitute
forward-looking information within the meaning of applicable
Canadian provincial securities legislation (collectively,
"forward-looking statements"). These forward-looking statements
relate to, among other things, our objectives, goals, targets,
strategies, intentions, plans, beliefs, estimates and outlook,
including, without limitation, our anticipated future operating
results, and can, in some cases, be identified by the use of words
such as "believe," "anticipate," "expect," "intend," "plan,"
"will," "may" and other similar expressions. In addition, any
statements that refer to expectations, projections or other
characterizations of future events or circumstances are
forward-looking statements.
These statements reflect management's current beliefs and are
based on information currently available to management. Certain
material factors or assumptions are applied in making
forward-looking statements, and actual results may differ
materially from those expressed or implied in such statements.
Important factors that could cause actual results to differ
materially from these expectations include, among other things:
DiaMedica's early stage of development, lack of product revenues
and history of operating losses, uncertainties related to clinical
trials and product development, rapid technological change,
uncertainties related to forecasts, competition, potential product
liability, additional financing requirements and access to capital,
unproven markets, supply of raw materials, income tax matters,
management of growth, partnerships for development and
commercialization of technology, effects of insurers' willingness
to pay for products, system failures, dependence on key personnel,
foreign currency risk, risks related to regulatory matters and
risks related to intellectual property and other risks detailed
from time to time in DiaMedica's filings with Canadian securities
regulatory authorities, as well as DiaMedica's ability to
anticipate and manage the risks associated with the foregoing.
Additional information about these factors and about the material
factors or assumptions underlying such forward-looking statements
may be found in the body of this news release, as well as under the
heading "Risk Factors" contained in DiaMedica's final long-form
prospectus dated March 12, 2007. DiaMedica cautions that the
foregoing list of important factors that may affect future results
is not exhaustive. When relying on DiaMedica's forward-looking
statements to make decisions with respect to DiaMedica, investors
and others should carefully consider the foregoing factors and
other uncertainties and potential events.
These risks and uncertainties should be considered carefully and
prospective investors should not place undue reliance on the
forward-looking statements. Although the forward-looking statements
contained in this press release are based upon what management
believes to be reasonable assumptions, DiaMedica cannot provide
assurance that actual results will be consistent with these
forward-looking statements. DiaMedica undertakes no obligation to
update or revise any forward-looking statement.
The TSX Venture Exchange does not accept responsibility for the
adequacy or accuracy of this release.
Contacts: DiaMedica Inc. Kevin Richardson, Ph.D. 204-478-5605
204-453-3745 (FAX) krichardson@diamedica.com www.diamedica.com
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