RNS Number:8436T
Antisoma PLC
05 January 2004


Antisoma plc
Director Shareholdings


London, UK, 5 January 2004: Antisoma plc (LSE: ASM) announces that the following
Directors have made purchases of Antisoma shares pursuant to the Placing and
Open Offer that was approved by shareholders on Thursday 18 December 2003.

Director/senior             Shares purchased @           New holding in 
executive                        40p per share             Antisoma plc


Glyn Edwards                            25,000                  652,127
Raymond Spencer                         33,705                  235,940
Barry Price                             49,210                  541,312
Grahame Cook                            31,521                  258,570


Enquiries

Antisoma plc
Raymond Spencer, Chief Financial Officer             Tel: +44 (0)20 8799 8200


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