ANEW MEDICAL, Inc. Announces Name Change to Klotho Neurosciences, Inc.
17 September 2024 - 8:30PM
The Board of ANEW MEDICAL, INC. (NASDAQ: WENA), today announced a
name and ticker symbol change to Klotho Neurosciences, Inc.
(NASDAQ: KLTO), and has launched a new website,
www.klothoneuro.com. The name and ticker change will have no impact
on current shareholders, and there is no action required on their
part.
The new name embodies the Company's commitment to strategically
direct its core investments of time and financial resources toward
the multibillion-dollar market opportunities for the company’s
patented Klotho gene technology assets in the neurosciences sector.
Through its exclusive worldwide license, the company’s patent
protected secreted form of the Klotho gene, s-KL, provides Klotho
Neurosciences with the opportunity to invest its strategic
resources into two distinct major market segments.
Innovative Prescription Drugs for Neurodegenerative
Diseases
The first is the development of new and highly innovative
prescription drugs for the treatment of neurodegenerative diseases
and age related disorders.
From this point forward, Klotho Neurosciences will focus
significant attention on the development of its lead candidate, a
novel treatment for Amyotrophic Lateral Sclerosis (ALS - also known
as Lou Gehrig’s disease), where the company hopes to expeditiously
gain FDA approval to enter the clinic.
The other key neurological areas of strategic focus for the
company are the development of novel therapeutics to treat
Alzheimer’s and Parkinson’s disease utilizing the company’s
proprietary s-KL gene therapy platform. In these indication areas,
and other age-related disorders, the company foresees the potential
of entering into research collaborations and partnership agreements
with major pharmaceutical companies that are strategically
investing in these specific areas.
Healthy Longevity
The second is the potential to increase healthy longevity or
lifespan using the company’s patented s-KL. In pursuit of this,
Klotho Neurosciences has entered into an important collaboration
with the “Blue Zone” researchers at the Okinawa Research Center for
Longevity Science (ORCLS) based in Japan and Hawaii. These
researchers have been studying Centenarians and healthy long life
spans for many years, and have collected and stored blood samples
from these healthy long living individuals. By analyzing these
samples, the company anticipates that it will be possible to
determine s-KL and Klotho blood and tissue levels in these healthy,
long-living persons. Based on preliminary data, the company
anticipates that the data will confirm that Klotho protein
expression is normalized (not depleted) in these people with long
life spans as compared to age-matched control groups. This work
will also enable Klotho Neurosciences to validate the clinical
assays that are needed for this study which, in the future, may be
used to identify persons at high risk for the development of
‘accelerated aging’ and neurologic pathologies. The benefit of this
would be that physicians would be able to intercede more promptly
in an intervention to provide treatments for these neurologic
pathologies prior to persons presenting with advanced disease.
Dr. Joseph Sinkule, Chairman, CEO, and Founder commented: “Our
new name truly reflects our strategic area of focus going forward.
We are excited in particular about the potential of developing
novel therapeutics to treat the devastating neurodegenerative
disorders such as ALS. Alzheimer’s and Parkinson’s disease, based
on our patented secreted form of the Klotho gene, s-KL. The Klotho
gene is referred to as the ‘anti-aging gene’ because studies have
shown that over-expression of the gene results in improved
cognition and a prolonged life span, whereas, conversely, an
absence of the gene and gene transcript causes rapid death from
age-related pathologies.”
Dr. Shalom Hirschman, the company’s Chief Medical Advisor,
added: “The data in a severe animal model of human ALS is very
compelling. Our plan is to meet with the FDA as soon as possible to
discuss the IND and propose a timetable for the potential
commencement of clinical trials in ALS patients.”
About Klotho Neurosciences, Inc.Klotho
Neurosciences, Inc. formerly ANEW MEDICAL, INC., is a Nasdaq-listed
pharmaceutical company with the ticker symbol
KLTO. The company specializes in the development
of patented, novel disease-modifying technologies targeting the
brain and central nervous system (CNS) that are seen as key
developments in treating neurodegenerative and age-related
disorders. The Company obtained exclusive worldwide rights to
platform technologies and knowhow to develop cutting edge protein,
gene and cell therapies to treat age-related pathologies such as
ALS, Alzheimer’s and Parkinson’s disease, multiple sclerosis, and
rare neurodegenerative diseases. The company is managed by a team
of individuals and advisors that are highly experienced in medical
product development and commercialization of medical products. For
additional information, please visit www.klothoneuro.com.
For more information, contact:Eric Boyd,
Investor RelationsEmail: IR@klothoneuro.com Website:
www.klothoneuro.com
Forward-Looking Statements:This press release
contains forward-looking statements. These statements are made
under the “safe harbor” provisions of the U.S. Private Securities
Litigation Reform Act of 1995. These forward-looking statements
generally are identified by the words “believe,” “project,”
“expect,” “anticipate,” “estimate,” “intend,” “strategy,” “future,”
“opportunity,” “plan,” “may,” “should,” “will,” “would,” “will be,”
“will continue,” “will likely result,” and similar expressions.
Without limiting the generality of the foregoing, the
forward-looking statements in this press release include
descriptions of the Company’s future commercial operations.
Forward-looking statements are predictions, projections and other
statements about future events that are based on current
expectations and assumptions and, as a result, are subject to risks
and uncertainties. Many factors could cause actual future events to
differ materially from the forward-looking statements in this press
release, such as the Company’s inability to implement its business
plans, identify and realize additional opportunities, or meet or
exceed its financial projections and changes in the regulatory or
competitive environment in which the Company operates. You should
carefully consider the foregoing factors and the other risks and
uncertainties described in the documents filed or to be filed by
the Company with the U.S. Securities and Exchange Commission (the
“SEC”) from time to time, which could cause actual events and
results to differ materially from those contained in the
forward-looking statements. Copies of these documents are available
on the SEC’s website, www.sec.gov. All information provided herein
is as of the date of this press release, and the Company undertakes
no obligation to update any forward-looking statement, except as
required under applicable law.
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