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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549
FORM 10-Q
(Mark One) | | | | | |
☒ | QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
For the quarterly period ended September 30, 2023
OR
| | | | | |
☐ | TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
For the transition period from to
Commission File Number: 001-35518
SUPERNUS PHARMACEUTICALS, INC.
(Exact name of registrant as specified in its charter) | | | | | | | | | | | | |
Delaware | | | | 20-2590184 |
(State or other jurisdiction of incorporation or organization) | | | | (I.R.S. Employer Identification No.) |
| | | | |
9715 Key West Avenue | Rockville | MD | | 20850 |
(Address of principal executive offices) | | | | (Zip Code) |
(301) 838-2500
(Registrant’s telephone number, including area code)
Indicate by check mark whether the registrant: (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. ☒ Yes ☐ No
Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files).
☒ Yes No ☐
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act. | | | | | | | | | | | | |
Large accelerated filer | ☒
| | Accelerated filer | ☐ |
| | | | |
Non-accelerated filer | ☐ | | Smaller reporting company | ☐ |
| | | | |
| | | Emerging growth company | ☐ |
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. o
Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). ☐ Yes ☒ No
Securities registered pursuant to Section 12(b) of the Exchange Act: | | | | | | | | | | | | | | | | | | | | |
Title of each class | | Outstanding at November 1, 2023 | | Trading Symbol | | Name of each exchange on which registered |
Common Stock, $0.001 par value per share | | 54,632,847 | | SUPN | | The Nasdaq Global Market |
SUPERNUS PHARMACEUTICALS, INC.
FORM 10-Q — QUARTERLY REPORT
FOR THE QUARTERLY PERIOD ENDED September 30, 2023
PART I — FINANCIAL INFORMATION
Supernus Pharmaceuticals, Inc.
Condensed Consolidated Balance Sheets
(in thousands, except share data) | | | | | | | | | | | |
| September 30, | | December 31, |
| 2023 | | 2022 |
| (unaudited) | | |
Assets | | | |
Current assets | | | |
Cash and cash equivalents | $ | 94,985 | | | $ | 93,120 | |
Marketable securities | 105,204 | | | 368,214 | |
Accounts receivable, net | 141,764 | | | 165,497 | |
Inventories, net | 83,480 | | | 91,541 | |
Prepaid expenses and other current assets | 23,927 | | | 15,779 | |
Total current assets | 449,360 | | | 734,151 | |
Long-term marketable securities | 25,125 | | | 93,896 | |
Property and equipment, net | 13,688 | | | 15,173 | |
Intangible assets, net | 641,147 | | | 702,463 | |
Goodwill | 117,019 | | | 117,019 | |
Other assets | 38,821 | | | 39,806 | |
Total assets | $ | 1,285,160 | | | $ | 1,702,508 | |
| | | |
Liabilities and stockholders’ equity | | | |
Current liabilities | | | |
Accounts payable and accrued liabilities | $ | 78,471 | | | $ | 96,342 | |
Accrued product returns and rebates | 162,473 | | | 151,665 | |
Convertible notes, net | — | | | 401,968 | |
Contingent consideration, current portion | 45,880 | | | 21,120 | |
Other current liabilities | 710 | | | 16,863 | |
Total current liabilities | 287,534 | | | 687,958 | |
Contingent consideration, long-term | 7,774 | | | 33,847 | |
Operating lease liabilities, long-term | 33,841 | | | 35,998 | |
Deferred income tax liabilities, net | 35,224 | | | 49,809 | |
Other liabilities | 8,596 | | | 8,692 | |
Total liabilities | 372,969 | | | 816,304 | |
| | | |
Stockholders’ equity | | | |
Common stock, $0.001 par value; 130,000,000 shares authorized; 54,630,758 and 54,253,796 shares issued and outstanding as of September 30, 2023 and December 31, 2022, respectively | 55 | | | 54 | |
Additional paid-in capital | 431,956 | | | 408,115 | |
Accumulated other comprehensive loss, net of tax | (1,206) | | | (3,210) | |
Retained earnings | 481,386 | | | 481,245 | |
Total stockholders’ equity | 912,191 | | | 886,204 | |
| | | |
Total liabilities and stockholders’ equity | $ | 1,285,160 | | | $ | 1,702,508 | |
See accompanying notes.
Supernus Pharmaceuticals, Inc.
Condensed Consolidated Statements of Earnings (Loss)
(in thousands, except share and per share data)
| | | | | | | | | | | | | | | | | | | | | | | |
| Three Months Ended September 30, | | Nine Months Ended September 30, |
| 2023 | | 2022 | | 2023 | | 2022 |
| (unaudited) | | (unaudited) |
Revenues | | | | | | | |
Net product sales | $ | 149,004 | | | $ | 172,724 | | | $ | 417,915 | | | $ | 485,647 | |
Royalty revenues | 4,876 | | | 4,629 | | | 25,292 | | | 14,263 | |
Total revenues | 153,880 | | | 177,353 | | | 443,207 | | | 499,910 | |
| | | | | | | |
Costs and expenses | | | | | | | |
Cost of goods sold | 19,601 | | | 25,878 | | | 64,152 | | | 64,267 | |
Research and development | 22,655 | | | 19,554 | | | 68,246 | | | 56,778 | |
Selling, general and administrative | 82,700 | | | 112,314 | | | 255,079 | | | 303,249 | |
Amortization of intangible assets | 21,242 | | | 20,644 | | | 61,316 | | | 61,932 | |
Contingent consideration expense (gain) | (456) | | | 486 | | | (1,313) | | | 1,894 | |
Total costs and expenses | 145,742 | | | 178,876 | | | 447,480 | | | 488,120 | |
| | | | | | | |
Operating earnings (loss) | 8,138 | | | (1,523) | | | (4,273) | | | 11,790 | |
| | | | | | | |
Other income (expense) | | | | | | | |
Interest expense | — | | | (1,724) | | | (2,415) | | | (5,476) | |
Interest and other income, net | 1,751 | | | 2,803 | | | 8,467 | | | 19,289 | |
Total other income (expense) | 1,751 | | | 1,079 | | | 6,052 | | | 13,813 | |
| | | | | | | |
Earnings (loss) before income taxes | 9,889 | | | (444) | | | 1,779 | | | 25,603 | |
| | | | | | | |
Income tax expense (benefit) | 25,865 | | | (2,193) | | | 1,638 | | | (9,627) | |
Net earnings (loss) | $ | (15,976) | | | $ | 1,749 | | | $ | 141 | | | $ | 35,230 | |
| | | | | | | |
Earnings (loss) per share | | | | | | | |
Basic | $ | (0.29) | | | $ | 0.03 | | | $ | 0.00 | | | $ | 0.66 | |
Diluted | $ | (0.29) | | | $ | 0.03 | | | $ | 0.00 | | | $ | 0.62 | |
| | | | | | | |
Weighted average shares outstanding | | | | | | | |
Basic | 54,608,963 | | | 53,789,674 | | | 54,498,687 | | | 53,517,838 | |
Diluted | 54,608,963 | | | 55,034,838 | | | 55,574,922 | | | 61,543,121 | |
See accompanying notes.
Supernus Pharmaceuticals, Inc.
Condensed Consolidated Statements of Comprehensive Earnings (Loss)
(in thousands)
| | | | | | | | | | | | | | | | | | | | | | | |
| Three Months Ended September 30, | | Nine Months Ended September 30, |
| 2023 | | 2022 | | 2023 | | 2022 |
| (unaudited) | | (unaudited) |
Net earnings (loss) | $ | (15,976) | | | $ | 1,749 | | | $ | 141 | | | $ | 35,230 | |
Other comprehensive gain (loss) | | | | | | | |
Unrealized gain (loss) on marketable securities, net of tax | 569 | | | (1,826) | | | 2,004 | | | (5,585) | |
Other comprehensive gain (loss) | 569 | | | (1,826) | | | 2,004 | | | (5,585) | |
Comprehensive earnings (loss) | $ | (15,407) | | | $ | (77) | | | $ | 2,145 | | | $ | 29,645 | |
See accompanying notes.
Supernus Pharmaceuticals, Inc.
Condensed Consolidated Statements of Changes in Stockholders’ Equity
Nine Months Ended September 30, 2023 and 2022
(unaudited, in thousands, except share data)
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
j | Common Stock | | Additional Paid-in Capital | | Accumulated Other Comprehensive Earnings (Loss) | | Retained Earnings | | Total Stockholders’ Equity |
| Shares | | Amount | | | | |
Balance, December 31, 2022 | 54,253,796 | | | $ | 54 | | | $ | 408,115 | | | $ | (3,210) | | | $ | 481,245 | | | $ | 886,204 | |
Share-based compensation | — | | | — | | | 6,306 | | | — | | | — | | | 6,306 | |
Issuance of common stock under the equity award plans, net of shares withheld for employee taxes | 216,826 | | | — | | | 1,811 | | | — | | | — | | | 1,811 | |
Net earnings | — | | | — | | | — | | | — | | | 16,948 | | | 16,948 | |
Unrealized gain on marketable securities, net of tax | — | | | — | | | — | | | 881 | | | — | | | 881 | |
Balance, March 31, 2023 | 54,470,622 | | | $ | 54 | | | $ | 416,232 | | | $ | (2,329) | | | $ | 498,193 | | | $ | 912,150 | |
Share-based compensation | — | | | — | | | 6,088 | | | — | | | — | | | 6,088 | |
Issuance of common stock under the equity award plans, net of shares withheld for employee taxes | 122,279 | | | 1 | | | 1,946 | | | — | | | — | | | 1,947 | |
Net loss | — | | | — | | | — | | | — | | | (831) | | | (831) | |
Unrealized gain on marketable securities, net of tax | — | | | — | | | — | | | 554 | | | — | | | 554 | |
Balance, June 30, 2023 | 54,592,901 | | | $ | 55 | | | $ | 424,266 | | | $ | (1,775) | | | $ | 497,362 | | | $ | 919,908 | |
Share-based compensation | — | | | — | | | 7,920 | | | — | | | — | | | 7,920 | |
Issuance of common stock under the equity award plans, net of shares withheld for employee taxes | 37,857 | | | — | | | (230) | | | — | | | — | | | (230) | |
Net loss | — | | | — | | | — | | | — | | | (15,976) | | | (15,976) | |
Unrealized loss on marketable securities, net of tax | — | | | — | | | — | | | 569 | | | — | | | 569 | |
Balance, September 30, 2023 | 54,630,758 | | | $ | 55 | | | $ | 431,956 | | | $ | (1,206) | | | $ | 481,386 | | | $ | 912,191 | |
Supernus Pharmaceuticals, Inc.
Condensed Consolidated Statements of Changes in Stockholders’ Equity
Nine Months Ended September 30, 2023 and 2022
(unaudited, in thousands, except share data)
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Common Stock | | Additional Paid-in Capital | | Accumulated Other Comprehensive Earnings (Loss) | | Retained Earnings | | Total Stockholders’ Equity |
| Shares | | Amount | | | | |
Balance, December 31, 2021 | 53,256,094 | | | $ | 53 | | | $ | 434,337 | | | $ | 1,539 | | | $ | 379,922 | | | $ | 815,851 | |
Cumulative effect of adoption of ASU 2020-06 | — | | | — | | | (56,212) | | | — | | | 40,612 | | | (15,600) | |
Balance, January 1, 2022 | 53,256,094 | | | 53 | | | 378,125 | | | 1,539 | | | 420,534 | | | 800,251 | |
Share-based compensation | — | | | — | | | 4,025 | | | — | | | — | | | 4,025 | |
Issuance of common stock in connection with the Company’s equity award plans | 130,211 | | | — | | | 866 | | | — | | | — | | | 866 | |
Net earnings | — | | | — | | | — | | | — | | | 25,616 | | | 25,616 | |
Unrealized loss on marketable securities, net of tax | — | | | — | | | — | | | (2,312) | | | — | | | (2,312) | |
Balance, March 31, 2022 | 53,386,305 | | | $ | 53 | | | $ | 383,016 | | | $ | (773) | | | $ | 446,150 | | | $ | 828,446 | |
Share-based compensation | — | | | — | | | 4,297 | | | — | | | — | | | 4,297 | |
Issuance of common stock in connection with the Company’s equity award plans | 106,081 | | | — | | | 2,273 | | | — | | | — | | | 2,273 | |
Net earnings | — | | | — | | | — | | | — | | | 7,865 | | | 7,865 | |
Unrealized loss on marketable securities, net of tax | — | | | — | | | — | | | (1,447) | | | — | | | (1,447) | |
Balance, June 30, 2022 | 53,492,386 | | | $ | 53 | | | $ | 389,586 | | | $ | (2,220) | | | $ | 454,015 | | | $ | 841,434 | |
Share-based compensation | — | | | — | | | 4,985 | | | — | | | — | | | 4,985 | |
Issuance of common stock in connection with the Company’s equity award plans | 561,127 | | | 1 | | | 6,455 | | | — | | | — | | | 6,456 | |
Net earnings | — | | | — | | | — | | | — | | | 1,749 | | | 1,749 | |
Unrealized loss on marketable securities, net of tax | — | | | — | | | — | | | (1,826) | | | — | | | (1,826) | |
Balance, September 30, 2022 | 54,053,513 | | | $ | 54 | | | $ | 401,026 | | | $ | (4,046) | | | $ | 455,764 | | | $ | 852,798 | |
See accompanying notes.
Supernus Pharmaceuticals, Inc.
Condensed Consolidated Statements of Cash Flows
(in thousands) | | | | | | | | | | | |
| Nine Months Ended September 30, |
| 2023 | | 2022 |
| (unaudited) |
Cash flows from operating activities | | | |
Net earnings | $ | 141 | | | $ | 35,230 | |
Adjustments to reconcile net earnings (loss) to net cash provided by operating activities: | | | |
Depreciation and amortization | 63,183 | | | 64,694 | |
Other income from Navitor (see Note 4) | — | | | (12,888) | |
Amortization of deferred financing costs and debt discount | 532 | | | 1,582 | |
Realized gains from sales of marketable securities | — | | | (14) | |
Amortization of premium/discount on marketable securities | (849) | | | 3,215 | |
Change in fair value of contingent consideration | (1,313) | | | 1,894 | |
Other noncash adjustments, net | 10,485 | | | 7,983 | |
Share-based compensation expense | 20,314 | | | 13,307 | |
Deferred income tax benefit | (15,255) | | | (18,564) | |
Changes in operating assets and liabilities: | | | |
Accounts receivable | 21,155 | | | (14,958) | |
Inventories | 1,082 | | | (6,304) | |
Prepaid expenses and other assets | (8,138) | | | 3,098 | |
Accrued product returns and rebates | 10,808 | | | 25,746 | |
Accounts payable and other liabilities | (36,018) | | | (12,659) | |
Contingent consideration | — | | | (2,100) | |
Net cash provided by operating activities | 66,127 | | | 89,262 | |
| | | |
Cash flows from investing activities | | | |
Purchases of marketable securities | — | | | (340,665) | |
Sales and maturities of marketable securities | 335,297 | | | 173,189 | |
Purchases of property and equipment | (587) | | | (422) | |
Net cash provided by (used in) investing activities | 334,710 | | | (167,898) | |
| | | |
Cash flows from financing activities | | | |
Proceeds from Line of Credit | 93,000 | | | — | |
Payments on Line of Credit | (93,000) | | | — | |
Payment on convertible notes | (402,500) | | | — | |
Payment of contingent consideration | — | | | (22,900) | |
Proceeds from issuance of common stock | 3,528 | | | 9,594 | |
Net cash used in financing activities | (398,972) | | | (13,306) | |
| | | |
Net change in cash and cash equivalents | 1,865 | | | (91,942) | |
Cash and cash equivalents at beginning of year | 93,120 | | | 203,434 | |
Cash and cash equivalents at end of period | $ | 94,985 | | | $ | 111,492 | |
| | | |
Supplemental cash flow information | | | |
Cash paid for interest on debt | $ | 1,946 | | | $ | 2,516 | |
Cash paid for income taxes | 27,055 | | | 14,558 | |
Cash paid for operating leases | 13,242 | | | 9,547 | |
| | | |
Noncash investing and financing activities | | | |
Lease assets obtained for new operating leases | $ | 5,903 | | | $ | 973 | |
Deferred legal fees and fixed assets included in accounts payable and accrued expenses | — | | | 144 | |
Property and equipment additions from utilization of tenant improvement allowance | — | | | 580 | |
See accompanying notes.
Supernus Pharmaceuticals, Inc.
Notes to Condensed Consolidated Financial Statements (unaudited)
1. Business Organization
Supernus Pharmaceuticals, Inc. (the "Company", see Note 2, Consolidation) is a biopharmaceutical company focused on developing and commercializing products for the treatment of central nervous system (CNS) diseases. The Company's diverse neuroscience portfolio includes approved treatments for epilepsy, migraine, attention-deficit hyperactivity disorder (ADHD), hypomobility in Parkinson’s Disease (PD), cervical dystonia, chronic sialorrhea, dyskinesia in PD patients receiving levodopa-based therapy, and drug-induced extrapyramidal reactions in adult patients. The Company is developing a broad range of novel CNS product candidates including new potential treatments for hypomobility in PD, epilepsy, depression, and other CNS disorders.
The Company has eight commercial products that it markets: Qelbree®, GOCOVRI®, Trokendi XR®, Oxtellar XR®, APOKYN®, XADAGO®, Osmolex ER®, and MYOBLOC®. In addition, SPN-830 (apomorphine infusion device) is a late-stage drug/device combination product candidate for the continuous treatment of motor fluctuations ("off" episodes) in PD patients that are not adequately controlled with oral levodopa and one or more adjunct PD medications.
2. Summary of Significant Accounting Policies
Basis of Presentation
The Company’s unaudited condensed consolidated financial statements have been prepared in accordance with the requirements of the U.S. Securities and Exchange Commission (SEC) for interim financial information. As permitted under Generally Accepted Accounting Principles in the United States (U.S. GAAP), certain notes and other information have been omitted from the interim unaudited condensed consolidated financial statements presented in this Quarterly Report on Form 10-Q. Therefore, these unaudited condensed consolidated financial statements should be read in conjunction with the Company’s most recent Annual Report on Form 10-K, for the year ended December 31, 2022, filed with the SEC.
In management’s opinion, the unaudited condensed consolidated financial statements include all normal and recurring adjustments necessary for a fair presentation of the Company’s financial position, results of operations, and cash flows. The results of operations for any interim period are not necessarily indicative of the Company’s future quarterly or annual results.
The Company, which is primarily located in the U.S., operates in one operating segment.
Consolidation
The Company's unaudited condensed consolidated financial statements include the accounts of Supernus Pharmaceuticals, Inc. and its wholly owned subsidiaries. These are collectively referred to herein as "Supernus" or "the Company." Supernus Pharmaceuticals, Inc. and each of its subsidiaries are distinct legal entities. All significant intercompany transactions and balances have been eliminated in consolidation.
The unaudited condensed consolidated financial statements reflect the consolidation of entities in which the Company has a controlling financial interest. In determining whether there is a controlling financial interest, the Company considers if it has a majority of the voting interests of the entity, or if the entity is a variable interest entity (VIE) and if the Company is the primary beneficiary. In determining the primary beneficiary of a VIE, the Company evaluates whether it has both: the power to direct the activities of the VIE that most significantly impact the VIE's economic performance; and the obligation to absorb losses of, or the right to receive benefits from the VIE that could potentially be significant to that VIE. The Company's judgment with respect to its level of influence or control of an entity involves the consideration of various factors, including the form of an ownership interest; representation in the entity's governance; the size of the investment; estimates of future cash flows; the ability to participate in policymaking decisions; and the rights of the other investors to participate in the decision making process, including the right to liquidate the entity, if applicable. If the Company is not the primary beneficiary of the VIE, and an ownership interest is maintained in the entity, the interest is accounted for under the equity or cost methods of accounting, as appropriate.
The Company continuously assesses whether it is the primary beneficiary of a VIE as changes to existing relationships or future transactions may affect its conclusions.
Use of Estimates
The Company bases its estimates on: historical experience; forecasts; information received from its service providers; information from other sources, including public and proprietary sources; and other assumptions that the Company believes are reasonable under the circumstances. Actual results could differ materially from the Company’s estimates. The Company periodically evaluates the methodologies employed in making its estimates.
Advertising Expense
Advertising expense includes the cost of promotional materials and activities, such as printed materials and digital marketing, marketing programs and speaker programs. The costs of the Company's advertising efforts are expensed as incurred.
The Company incurred approximately $25.1 million and $76.9 million in advertising expense for the three and nine months ended September 30, 2023, respectively, and approximately $52.0 million and $112.8 million for the three and nine months ended September 30, 2022. These expenses are recorded as a component of Selling, general and administrative expenses in the unaudited condensed consolidated statements of earnings (loss).
Restricted Cash
On March 30, 2023, the Company transferred funds totaling $403.8 million, which was reported as restricted cash in the first quarter of 2023, to the Trustee (Wilmington Trust) related to the repayment of the 2023 Notes. On April 1, 2023, the Company paid the total principal amount due of $402.5 million under the 2023 Notes and the remaining outstanding interest due of $1.3 million with the restricted cash. Refer to Note 8, Debt.
Line of Credit
Line of credit includes borrowings under the uncommitted demand secured line of credit. On February 8, 2023, the Company entered into a credit line agreement (the “Credit Line”) with UBS Bank USA (“UBS”). The Credit Line provides for a revolving line of credit of up to $150 million, which can be drawn at any time. Refer to Note 8, Debt.
Recently Issued Accounting Pronouncements
Accounting Pronouncements Adopted
Accounting Standards Update (ASU) 2020-06, Debt - Debt with Conversion and Other Options (Subtopic 470-20) and Derivatives and Hedging - Contracts in Entity's Own Equity (Subtopic 815-40): Accounting for Convertible Instruments and Contracts in an Entity's Own Equity - The new standard, issued in August 2020, simplifies the accounting for certain financial instruments with characteristics of liabilities and equity, including convertible debt instruments with cash conversion and beneficial conversion features. ASU 2020-06 eliminates requirements to separately account for liability and equity components of such convertible debt instruments and eliminates the ability to use the treasury stock method for calculating diluted earnings per share for convertible instruments whose principal amount may be settled in whole or in part with equity. Instead, ASU 2020-06 requires (i) the entire amount of the security to be presented as a liability on the balance sheet and (ii) application of the “if-converted” method for calculating diluted earnings per share. This new standard also removes certain settlement conditions required for equity contracts to qualify for the derivative scope exception.
The Company adopted the new guidance as of January 1, 2022 using the modified retrospective method of transition which allows for a cumulative-effect adjustment to the opening balance of retained earnings in the period of adoption. As a result, the cumulative effect of the accounting change increased the carrying amount of the convertible notes, net by $20.6 million, increased retained earnings by $40.6 million, reduced additional paid-in capital by $56.2 million, and decreased deferred tax liabilities by $5.0 million as of January 1, 2022. Upon adoption, the Company began calculating diluted earnings per share under the if-converted method.
3. Disaggregated Revenues
The following table summarizes the disaggregation of revenues by product or source, (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | |
| Three Months Ended September 30, | | Nine Months Ended September 30, |
| 2023 | | 2022 | | 2023 | | 2022 |
| (unaudited) | | (unaudited) |
Net product sales | | | | | | | |
Qelbree | $ | 37,081 | | | $ | 18,326 | | | $ | 93,840 | | | $ | 37,708 | |
GOCOVRI | 32,889 | | | 27,878 | | | 87,650 | | | 75,179 | |
Oxtellar XR | 29,644 | | | 30,528 | | | 82,359 | | | 88,007 | |
Trokendi XR | 20,625 | | | 69,599 | | | 74,734 | | | 204,033 | |
APOKYN | 21,510 | | | 18,261 | | | 56,324 | | | 57,156 | |
Other(1) | 7,255 | | | 8,132 | | | 23,008 | | | 23,564 | |
Total net product sales | $ | 149,004 | | | $ | 172,724 | | | $ | 417,915 | | | $ | 485,647 | |
Royalty revenues | 4,876 | | | 4,629 | | | 25,292 | | | 14,263 | |
Total revenues | $ | 153,880 | | | $ | 177,353 | | | $ | 443,207 | | | $ | 499,910 | |
___________________________________________
(1) Includes net product sales of MYOBLOC, XADAGO and Osmolex ER.
The decrease in Trokendi XR net product sales for the three and nine months ended September 30, 2023, compared to the same period in 2022 was primarily attributable to the loss of exclusivity with generic entrants in January 2023.
The following table shows the percentage of net product sales to total net product sales:
| | | | | | | | | | | | | | | | | | | | | | | |
| Percentage of Net Product Sales |
| Three Months Ended September 30, | | Nine Months Ended September 30, |
| 2023 | | 2022 | | 2023 | | 2022 |
Qelbree | 25% | | 11% | | 22% | | 8% |
GOCOVRI | 22% | | 16% | | 21% | | 15% |
Oxtellar XR | 20% | | 18% | | 20% | | 18% |
Trokendi XR | 14% | | 40% | | 18% | | 42% |
APOKYN | 14% | | 10% | | 13% | | 12% |
Other(1) | 5% | | 5% | | 6% | | 5% |
Total | 100% | | 100% | | 100% | | 100% |
___________________________________________(1) Includes net product sales of MYOBLOC, XADAGO and Osmolex ER.
Each of our three major customers, AmerisourceBergen Drug Corporation, Cardinal Health, Inc. and McKesson Corporation, individually accounted for more than 20% of our total net product sales and collectively accounted for more than 70% of our total net product sales for the three and nine months ended September 30, 2023 and 2022.
The Company recognized noncash royalty revenue of $4.0 million for the nine months ended September 30, 2023. The Company recognized noncash royalty revenue of $2.5 million and $7.2 million for the three and nine months ended September 30, 2022, respectively. Refer to Note 15, Commitments and Contingencies.
4. Investments
Marketable Securities
Unrestricted available-for-sale marketable securities held by the Company are as follows, (dollars in thousands): | | | | | | | | | | | |
| September 30, 2023 | | December 31, 2022 |
| (unaudited) | | |
Corporate and municipal debt securities | | | |
Amortized cost | $ | 131,891 | | | $ | 466,333 | |
Gross unrealized gains | 1 | | | 14 | |
Gross unrealized losses | (1,563) | | | (4,237) | |
Total fair value | $ | 130,329 | | | $ | 462,110 | |
The contractual maturities of the unrestricted available-for-sale marketable securities held by the Company are as follows, (dollars in thousands): | | | | | |
| September 30, 2023 |
| (unaudited) |
Less than 1 year | $ | 105,204 | |
1 year to 2 years | 25,125 | |
| |
| |
| |
Total | $ | 130,329 | |
As of September 30, 2023, there was no impairment due to credit loss on any available-for-sale marketable securities.
Investment in Navitor
Development Agreement
In April 2020, the Company entered into a development agreement (the Development Agreement) with Navitor Pharmaceuticals, Inc. (Navitor Inc.). The Company can terminate the Development Agreement upon 30 days' notice. Under the terms of the Development Agreement, the Company and Navitor Inc. will jointly conduct a Phase II clinical program for NV-5138 (SPN-820) for treatment-resistant depression. The Company will bear all of the Phase I and Phase II development costs incurred by either party, up to a maximum of $50 million. In addition, the Company will incur certain other research and development support costs. There are certain additional payment amounts which could be incurred by the Company. These costs are contingent upon Navitor Inc. achieving defined development milestones. The Company has an option to acquire or license NV-5138 (SPN-820), for which additional payments would be required.
Equity investment
In addition to entering into the Development Agreement in April 2020, the Company acquired Series D Preferred Shares of Navitor Inc. for $15 million, representing an approximately 13% ownership position in Navitor Inc.
In March 2021, Navitor Inc. underwent a legal restructuring. In the restructuring, Navitor Inc. became a wholly owned subsidiary of a newly formed limited liability company, Navitor Pharmaceuticals LLC (Navitor LLC), and the outstanding shares of stock in Navitor Inc. were exchanged for units of membership in Navitor LLC having equivalent rights and preferences (Navitor Restructuring). As part of the Navitor Restructuring, the Series D Preferred Shares previously held by the Company were exchanged for Series D Preferred Shares in Navitor LLC. In addition, certain assets that did not relate to NV-5138 (SPN-820) were transferred from Navitor Inc. to a newly formed entity that became a separate, wholly owned subsidiary of Navitor LLC.
The Company had determined that Navitor LLC is a VIE. The Company does not consolidate this VIE because the Company lacks the power to direct the activities that most significantly impact Navitor’s economic performance.
Prior to the Navitor Restructuring, the investment was accounted for under the practical expedient allowed for equity securities without readily determinable fair value, which is cost minus impairment plus any changes in observable price changes from an orderly transaction of similar investments in Navitor Inc. Following the legal restructuring and exchange of the preferred shares for member equity units of Navitor LLC, the investment was accounted for under the equity method of accounting due to the Company's ability to exert significant influence over but not control the financial and operating decisions of Navitor LLC. As
a result of the change from a cost method investment to an equity method investment, the Company was required to measure its investment initially in accordance with the guidance in ASC 805. The majority of the assets and liabilities recorded in Navitor LLC's financial statements represent working capital items and cash that are being used for research and development purposes and are significantly lower than the Company's investment in Navitor LLC, which created a significant basis difference for the Company's investment in the underlying net assets. The Company determined that substantially all of the fair value of the investment was attributable to a single in-process research and development (IPR&D) asset. As a result, Navitor LLC was not considered a business as defined in ASC 805. In the first quarter of 2021, the $15 million investment, which was previously recorded in Other assets in the unaudited condensed consolidated balance sheets, was expensed and recorded in Research and development expense.
The Company records its share of the results of Navitor LLC, a private company, on a quarter lag as the financial information of Navitor LLC is not available on a sufficiently timely basis for the Company to apply the equity method of accounting. In December 2021, Navitor LLC sold one of its subsidiaries and distributed cash to its members in accordance with each member's share of the proceeds from the sale. The Company received $12.9 million in December 2021 from Navitor LLC in connection with this sale. As the Company's policy is to record its share of the results in its equity method investment on a quarter lag as previously indicated, the Company recorded the cash amount received in Other current liabilities in the consolidated balance sheets as of December 31, 2021. In the first quarter of 2022, the Company determined its estimated share of Navitor LLC's year-end 2021 earnings and recorded a gain of $12.9 million in Interest and other income, net in the unaudited condensed consolidated statement of earnings (loss).
The maximum exposure to losses related to Navitor LLC is a maximum of approximately $50 million in expense for Phase I and Phase II development of NV-5138 (SPN-820), and the cost of other development and formulation activities provided by the Company.
Subsequent to the Development Agreement entered into in 2020, no additional equity investment has been made or financing has been provided to Navitor LLC.
5. Fair Value of Financial Measurements
The fair value of an asset or liability represents the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between unrelated market participants.
The Company reports the fair value of assets and liabilities using a three level measurement hierarchy that prioritizes the inputs used to measure fair value. Fair value hierarchy consists of the following three levels:
•Level 1—Valuations based on unadjusted quoted prices in active markets that are accessible at measurement date for identical assets.
•Level 2—Valuations based on quoted prices for similar assets or liabilities in active markets, quoted prices for identical or similar assets or liabilities in markets that are not active and model-based valuations in which all significant inputs are observable in the market, either directly or indirectly (e.g., interest rates; yield curves).
•Level 3—Valuations using significant inputs that are unobservable in the market and inputs that reflect the Company’s own assumptions. These are based on the best information available, including the Company’s own data.
The fair value of the restricted marketable securities is recorded in Other assets on the unaudited condensed consolidated balance sheets. There have been no transfers of assets or liabilities into or out of Level 3 of the fair value hierarchy.
Financial Assets and Liabilities Recorded at Fair Value
The Company’s financial assets that are required to be measured at fair value on a recurring basis are as follows (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | |
| | | Fair Value Measurements as of September 30, 2023 (unaudited) |
| Total Fair Value as of September 30, 2023 (unaudited) | | Level 1 | | Level 2 | | Level 3 |
Assets: | | | | | | | |
Cash and cash equivalents | | | | | | | |
Cash | $ | 38,302 | | | $ | 38,302 | | | $ | — | | | $ | — | |
Money market securities and funds | 56,683 | | | 56,683 | | | — | | | — | |
Marketable securities | | | | | | | |
Corporate and municipal debt securities | 105,204 | | | — | | | 105,204 | | | — | |
| | | | | | | |
Long-term marketable securities | | | | | | | |
Corporate and municipal debt securities | 25,125 | | | — | | | 25,125 | | | — | |
| | | | | | | |
Other assets | | | | | | | |
Marketable securities - restricted (SERP) | 512 | | | 14 | | | 498 | | | — | |
Total assets at fair value | $ | 225,826 | | | $ | 94,999 | | | $ | 130,827 | | | $ | — | |
Liabilities: | | | | | | | |
Contingent consideration | $ | 53,654 | | | $ | — | | | $ | — | | | $ | 53,654 | |
Total liabilities at fair value | $ | 53,654 | | | $ | — | | | $ | — | | | $ | 53,654 | |
| | | | | | | | | | | | | | | | | | | | | | | |
| | | Fair Value Measurements as of December 31, 2022 |
| Total Fair Value as of December 31, 2022 | | Level 1 | | Level 2 | | Level 3 |
Assets: | | | | | | | |
Cash and cash equivalents | | | | | | | |
Cash | $ | 52,181 | | | $ | 52,181 | | | $ | — | | | $ | — | |
Money market securities and funds | 40,939 | | | 40,939 | | | — | | | — | |
Marketable securities | | | | | | | |
Corporate and municipal debt securities | 368,214 | | | — | | | 368,214 | | | — | |
| | | | | | | |
Long-term marketable securities | | | | | | | |
Corporate and municipal debt securities | 93,896 | | | — | | | 93,896 | | | — | |
| | | | | | | |
Other assets | | | | | | | |
Marketable securities - restricted (SERP) | 496 | | | 11 | | | 485 | | | — | |
Total assets at fair value | $ | 555,726 | | | $ | 93,131 | | | $ | 462,595 | | | $ | — | |
Liabilities: | | | | | | | |
Contingent consideration | $ | 54,967 | | | $ | — | | | $ | — | | | $ | 54,967 | |
Total liabilities at fair value | $ | 54,967 | | | $ | — | | | $ | — | | | $ | 54,967 | |
Other Financial Instruments
The carrying amounts of other financial instruments, including accounts receivable, accounts payable, and accrued expenses approximate fair value due to their short-term maturities.
Financial Liabilities Recorded at Carrying Value
On April 1, 2023, the Company paid the total principal amount due of $402.5 million under the 2023 Notes and the outstanding interest due of $1.3 million.
As of December 31, 2022, the carrying value and fair value of the 2023 Notes which were not carried at fair value was as follows (dollars in thousands):
| | | | | | | | | | | |
| December 31, 2022 |
| Carrying Value | | Fair Value (Level 2) |
| | | |
Convertible notes, net | $ | 401,968 | | | $ | 395,959 | |
The fair value has been estimated based on actual trading information, and quoted prices, both provided by bond traders.
6. Contingent Consideration
The following table provides the current and long-term portions related to the contingent consideration for the USWM Acquisition and Adamas Acquisition (dollars in thousands):
| | | | | | | | | | | |
| September 30, 2023 | | December 31, 2022 |
Reported under the following captions in the condensed consolidated balance sheets: | (unaudited) | | |
Contingent consideration, current portion | $ | 45,880 | | | $ | 21,120 | |
Contingent consideration, long-term | 7,774 | | | 33,847 | |
Total | $ | 53,654 | | | $ | 54,967 | |
The Company's contingent consideration liabilities are related to the USWM Acquisition in 2020 and the Adamas Acquisition in 2021 (each acquisition as defined below). The contingent consideration liabilities are measured at fair value using either a Monte Carlo simulation or the income approach. The Company classifies its contingent consideration liabilities as Level 3 fair value measurements based on the significant unobservable inputs used to estimate fair value. These reflect the inputs and assumptions the Company believes would be made by market participants. Changes in any of those inputs together or in isolation may result in significantly lower or higher fair value measurement. The change in fair value is reported on the condensed consolidated statement of earnings (loss) in Contingent consideration (gain) expense.
USWM Contingent Consideration
On June 9, 2020 (the USWM Closing Date), the Company completed its acquisition of all the outstanding equity of USWM Enterprises, LLC (USWM Enterprises) (USWM Acquisition). The USWM Acquisition included potential additional contingent consideration payments for regulatory and development milestones and sales-based milestones. As of September 30, 2023, the potential contingent consideration payments are up to $85 million, which is comprised of the potential $55 million in regulatory and development milestones and $30 million in sales-based milestones.
•Regulatory and development milestones:
The potential $55 million in regulatory and development milestones is comprised of (1) $25 million related to the FDA's approval of the SPN-830 NDA and (2) $30 million related to the subsequent commercial product launch.
•Sales-based milestones:
The potential $30 million sales-based milestone relates to the achievement of certain net product sales of the acquired USWM products in 2023. As of September 30, 2023, the Company assessed that this remaining $30 million sales-based milestone will not be achieved based on net sales projections.
The key assumptions considered in estimating the fair value include the estimated probability and timing of milestone achievement, such as the probability and timing of obtaining regulatory approval, discount rate, and the estimated amount and timing of projected revenues from the acquired USWM products.
Adamas Contingent Consideration
On November 24, 2021 (the Adamas Closing Date), the Company completed its acquisition of all the outstanding equity of Adamas (Adamas Acquisition). The Adamas Acquisition included payment of two non-tradable contingent value rights (CVRs) each of which represents the contractual right to receive a contingent payment upon the achievement of the applicable aggregate worldwide net product sales of GOCOVRI.
Each CVR represents the contractual right to receive a contingent payment of $0.50 per share in cash, less any applicable withholding taxes and without interest, upon the achievement of the applicable milestone (each such amount, a Milestone Payment) in accordance with the terms of a Contingent Value Rights Agreement entered into between the Company and American Stock Transfer & Trust Company, LLC, as rights agent, as further defined in the CVR agreement. One Milestone Payment is payable (subject to certain terms and conditions) upon the first occurrence of the achievement of aggregate worldwide net sales of GOCOVRI in excess of $150 million during any consecutive 12-month period ending on or before December 31, 2024 (Milestone 2024). Another Milestone Payment is payable (subject to certain terms and conditions) upon the first occurrence of the achievement of aggregate worldwide net sales of GOCOVRI in excess of $225 million during any consecutive 12-month period ending on or before December 31, 2025 (Milestone 2025 and, together with Milestone 2024, the Milestones). Each Milestone may only be achieved once. The possible outcomes for the contingent consideration range from $0 to $50.9 million on an undiscounted basis.
The key assumptions considered in estimating the fair value of the Adamas sales-based milestones include the estimated revenue projections, volatility, estimated discount rates and risk-free interest rate.
Change in the Fair Value of Contingent Consideration
The following tables provide a reconciliation of the beginning and ending balances related to the contingent consideration for the USWM Acquisition and Adamas Acquisition (dollars in thousands): | | | | | | | | | | | | | | | | | |
| USWM Acquisition | | Adamas Acquisition | | Total |
Balance at December 31, 2022 | $ | 46,270 | | | $ | 8,697 | | | $ | 54,967 | |
Change in fair value recognized in earnings | (1,710) | | | 63 | | | (1,647) | |
Balance at March 31, 2023 (unaudited) | 44,560 | | | 8,760 | | | 53,320 | |
Change in fair value recognized in earnings | 660 | | | 130 | | | 790 | |
Balance at June 30, 2023 (unaudited) | 45,220 | | | 8,890 | | | 54,110 | |
Change in fair value recognized in earnings | 660 | | | (1,116) | | | (456) | |
Balance at September 30, 2023 (unaudited) | $ | 45,880 | | | $ | 7,774 | | | $ | 53,654 | |
| | | | | | | | | | | | | | | | | |
| USWM Acquisition | | Adamas Acquisition | | Total |
Balance at December 31, 2021 | $ | 70,170 | | | $ | 10,307 | | | $ | 80,477 | |
Milestone payments | (25,000) | | | — | | | (25,000) | |
Change in fair value recognized in earnings | 1,720 | | | (1,055) | | | 665 | |
Balance at March 31, 2022 (unaudited) | 46,890 | | | 9,252 | | | 56,142 | |
Change in fair value recognized in earnings | 350 | | | 393 | | | 743 | |
Balance at June 30, 2022 (unaudited) | 47,240 | | | 9,645 | | | 56,885 | |
Change in fair value recognized in earnings | 350 | | | 136 | | | 486 | |
Balance at September 30, 2022 (unaudited) | $ | 47,590 | | | $ | 9,781 | | | $ | 57,371 | |
The Company recorded a $0.7 million expense and a $0.4 million gain due to the change in the fair value of the contingent consideration liabilities for the USWM milestones for the three and nine months ended September 30, 2023 primarily driven by the passage of time in both periods, as well as the change in timing of milestone achievement and estimated discount rate in the first quarter of 2023. The Company recorded a $0.4 million expense and a $2.4 million expense due to the change in the fair value of the contingent consideration liabilities for the USWM milestones for the three and nine months ended September 30, 2022 primarily driven by the passage of time and the accretion to the payout amount related to the milestone achieved in the first quarter of 2022.
The Company recorded a $1.1 million gain and a $0.9 million gain due to the change in fair value of the contingent consideration liabilities for the Adamas CVRs for the three and nine months ended September 30, 2023 primarily driven by the passage of time. The Company recorded a $0.1 million expense and a $0.5 million gain due to the change in fair value of the contingent consideration liabilities for the Adamas CVRs for the three and nine months ended September 30, 2022 primarily driven by the passage of time.
The Company paid $25 million in the first quarter of 2022 of which $22.9 million represents the acquisition date fair value of the contingent consideration liability and was reported under cash flows from financing activities. The remaining $2.1 million represents the excess of the acquisition date fair value and was reported under cash flows from operating activities. The amount paid was for the milestone that was due upon the FDA acceptance of the SPN-830 NDA for review, which was achieved in the first quarter of 2022.
7. Intangible Assets, Net
The following table sets forth the gross carrying amounts and related accumulated amortization of intangibles assets (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | September 30, 2023 | | December 31, 2022 |
| | | (unaudited) | | | | | | |
| Remaining Weighted Average Life (Years) | | Carrying Amount, Gross | | Accumulated Amortization | | Carrying Amount, Net | | Carrying Amount, Gross | | Accumulated Amortization | | Carrying Amount, Net |
Acquired in-process research and development | | | $ | 124,000 | | | $ | — | | | $ | 124,000 | | | $ | 124,000 | | | $ | — | | | $ | 124,000 | |
Intangible assets subject to amortization: | | | | | | | | | | | | | |
Acquired developed technology and product rights | 7.08 | | 681,500 | | | (171,191) | | | 510,309 | | | 681,500 | | | (113,061) | | | 568,439 | |
Capitalized patent defense costs | 0.92 | | 43,820 | | | (36,982) | | | 6,838 | | | 43,820 | | | (33,796) | | | 10,024 | |
Total intangible assets | 7.00 | | $ | 849,320 | | | $ | (208,173) | | | $ | 641,147 | | | $ | 849,320 | | | $ | (146,857) | | | $ | 702,463 | |
Amortization expense for intangible assets was approximately $21.2 million and $61.3 million, for the three and nine months ended September 30, 2023 and approximately $20.6 million and $61.9 million for the three and nine months ended September 30, 2022, respectively.
U.S. patents covering Trokendi XR and Oxtellar XR will expire no earlier than 2027. In regard to Trokendi XR, the Company entered into settlement agreements that allowed third parties to enter the market on January 1, 2023. In regard to Oxtellar XR, the Company entered into settlement and license agreements that allows a third party to enter the market in September 2024, or sooner under certain conditions.
8. Debt
Convertible Senior Notes Due 2023
The 0.625% Convertible Senior Notes Due 2023 (2023 Notes), which were issued in March 2018, bore interest at an annual rate of 0.625%, payable semi-annually in arrears on April 1 and October 1 of each year. The 2023 Notes matured on April 1, 2023. On March 30, 2023, the Company transferred funds totaling $403.8 million to the Trustee (Wilmington Trust) related to the repayment of the 2023 Notes which was reported as restricted cash in the first quarter of 2023. On April 1, 2023, the Company paid the total principal amount due of $402.5 million under the 2023 Notes and the remaining outstanding interest due of $1.3 million with the restricted cash.
Contemporaneous with the issuance of the 2023 Notes, the Company also entered into separate privately negotiated convertible note hedge transactions (collectively, the Convertible Note Hedge Transactions) with each of the call spread counterparties. The Company issued 402,500 convertible note hedge options. As of March 31, 2023, the Convertible Note Hedges have expired.
Concurrently with entering into the Convertible Note Hedge Transactions, the Company also entered into separate privately negotiated warrant transactions (collectively, the Warrant Transactions) with each of the call spread counterparties. The
Company issued a total of 6,783,939 warrants. The warrants entitle the holder to one share per warrant. The strike price of the Warrant Transactions will initially be $80.91 per share of the Company’s common stock, and is subject to adjustment.
The Warrant Transactions were intended to partially offset the cost to the Company of the purchased Convertible Note Hedge Transactions; however, the Warrant Transactions could have a dilutive effect with respect to the Company’s common stock, to the extent that the market price per share of the Company’s common stock, as measured under the terms of the Warrant Transactions, exceeds the strike price of the warrants. The warrants expire in tranches, if unexercised, on or before November 22, 2023.
As of December 31, 2022, the liability component of the 2023 Notes consisted of the following, (dollars in thousands): | | | | | |
| December 31, 2022 |
| |
2023 Notes | $ | 402,500 | |
Unamortized debt discount and deferred financing costs | (532) | |
Total carrying value | $ | 401,968 | |
Uncommitted Demand Secured Line of Credit
On February 8, 2023, the Company entered into a credit line agreement with UBS. The Credit Line provides for a revolving line of credit of up to $150 million, which can be drawn at any time. Any fixed rate borrowing will bear interest at a fixed interest rate, equal to the sum of (i) the UBS Fixed Funding Rate (as defined in the Credit Line) plus (ii) the applicable Percentage Spread established in the Credit Line. Any variable rate borrowing will bear interest at a variable interest rate, equal to the sum of (i) the UBS Variable Rate (as defined in the Credit Line) plus (ii) the applicable Percentage Spread established in the Credit Line.
The Credit Line is secured by a first priority lien and security interest in certain of the Company’s assets, including each account of the Company at UBS Financial Services Inc. (the “Collateral Account”), and other such collateral (collectively, the "Collateral"), as further defined in the Credit Line. The Company may be required to post additional collateral if the value of the Collateral declines below the required collateral maintenance requirements.
Upon certain customary events of default, all amounts due under the Credit Line will become immediately due and payable without demand, and UBS has the right, in its discretion, to liquidate, transfer, withdraw or sell all or any part of the Collateral and apply the proceeds to repay any borrowings pursuant to the Credit Line.
The Company has the right to repay any variable rate advance under the Credit Line at any time, in whole or in part, without penalty. The Company may repay any fixed rate advance in whole, but may not repay any fixed rate advance in part. In its discretion and without cause, UBS has the right at any time to demand full or partial payment of amounts borrowed pursuant to the Credit Line and terminate the Credit Line.
On March 30, 2023, the Company borrowed $93.0 million under the Credit Line, which bore a variable interest rate. The funds from this borrowing were used to repay outstanding indebtedness under the 2023 Notes as discussed above under the Convertible Senior Notes Due 2023. As of June 30, 2023, the Company repaid the total principal balance of $93.0 million under the Credit Line and the interest incurred on the Credit Line of $0.7 million. As of September 30, 2023, there was no outstanding debt under the Credit Line.
9. Share-Based Payments
Share-based compensation expense is as follows (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | |
| Three Months Ended September 30, | | Nine Months Ended September 30, |
| 2023 | | 2022 | | 2023 | | 2022 |
| (unaudited) | | (unaudited) |
Research and development | $ | 1,254 | | | $ | 825 | | | $ | 3,458 | | | $ | 2,284 | |
Selling, general and administrative | 6,666 | | | 4,160 | | | 16,856 | | | 11,023 | |
Total | $ | 7,920 | | | $ | 4,985 | | | $ | 20,314 | | | $ | 13,307 | |
Stock Option and Stock Appreciation Rights
The following table summarizes stock option and stock appreciation rights (SAR) activities: | | | | | | | | | | | | | | | | | |
| Number of Options | | Weighted Average Exercise Price | | Weighted Average Remaining Contractual Term (in years) |
Outstanding, December 31, 2022 | 5,797,569 | | | $ | 26.99 | | | 6.11 |
Granted | 1,148,143 | | | $ | 38.28 | | | |
Exercised | (228,628) | | | $ | 17.50 | | | |
Forfeited | (91,986) | | | $ | 33.24 | | | |
Outstanding, September 30, 2023 (unaudited) | 6,625,098 | | | $ | 29.17 | | | 6.14 |
| | | | | |
As of September 30, 2023 (unaudited): | | | | | |
Vested and expected to vest | 6,625,098 | | | $ | 29.17 | | | 6.14 |
Exercisable | 4,116,000 | | | $ | 26.44 | | | 4.65 |
| | | | | |
As of December 31, 2022: | | | | | |
Vested and expected to vest | 5,797,569 | | | $ | 26.99 | | | 6.11 |
Exercisable | 3,541,395 | | | $ | 25.08 | | | 4.68 |
Restricted Stock Units
The following table summarizes restricted stock unit (RSU) activities:
| | | | | | | | | | | |
| Number of RSUs | | Weighted Average Grant Date Fair Value per Share |
Nonvested, December 31, 2022 | 131,960 | | | $ | 32.17 | |
Granted | 227,980 | | | $ | 38.60 | |
Vested | (47,049) | | | $ | 32.18 | |
Forfeited | (6,375) | | | $ | 34.63 | |
Nonvested, September 30, 2023 (unaudited) | 306,516 | | | $ | 36.90 | |
Performance Share Units
The following table summarizes performance share unit (PSU) activities:
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Performance-Based Units | | Market-Based Units | | Total PSUs |
| Number of PSUs | | Weighted Average Grant Date Fair Value per Share | | Number of PSUs | | Weighted Average Grant Date Fair Value per Share | | Number of PSUs | | Weighted Average Grant Date Fair Value per Share |
Nonvested, December 31, 2022 | 181,750 | | | $ | 29.07 | | | 20,000 | | | $ | 28.63 | | | 201,750 | | | $ | 29.03 | |
Granted | 205,000 | | | $ | 34.00 | | | — | | | $ | — | | | 205,000 | | | $ | 34.00 | |
Vested | (102,520) | | | $ | 31.04 | | | — | | | $ | — | | | (102,520) | | | $ | 31.04 | |
Forfeited | (3,000) | | | $ | 28.93 | | | — | | | $ | — | | | (3,000) | | | $ | 28.93 | |
Nonvested, September 30, 2023 (unaudited) | 281,230 | | $ | 31.95 | | | 20,000 | | $ | 28.63 | | | 301,230 | | $ | 31.73 | |
10. Earnings (Loss) per Share
Basic earnings (loss) per share is calculated using the weighted average number of common shares outstanding. Diluted earnings (loss) per share is calculated using the weighted average number of common shares outstanding, including the dilutive effect of the Company’s stock option grants, SARs, RSUs, employee stock purchase plan (ESPP) awards as determined per the treasury method, and the 2023 Notes, as determined per the if-converted method.
Effect of Convertible Notes and Related Convertible Note Hedges and Warrants
In connection with the issuance of the 2023 Notes, the Company entered into Convertible Note Hedge and Warrant Transactions as described further in Note 8, Debt. The expected collective impact of the Convertible Note Hedge and Warrant Transactions is to reduce the potential dilution that would occur if the price of the Company's common stock was between the conversion price of $59.33 per share and the strike price of the warrants of $80.91 per share.
Diluted earnings (loss) per share related to the 2023 Notes is calculated using the if-converted method. The number of dilutive shares is based on the initial conversion rate associated with the 2023 Notes. The Convertible Note Hedge and Warrant Transactions are excluded in the calculation of diluted earnings (loss) per share because inclusion would be anti-dilutive. Specifically, the denominator of the diluted earnings (loss) per share calculation excludes the additional shares related to the warrants because the average price of the Company's common stock was less than the strike price of the warrants of $80.91 per share. The Convertible Note Hedge Transactions are not considered in calculating diluted earnings (loss) per share as their impact would be anti-dilutive.
In addition to the above described effect of the 2023 Notes and the related Convertible Note Hedge and Warrant Transactions, the Company also excluded the common stock equivalents of the following outstanding stock-based awards and shares associated with the conversion of the 2023 Notes in the calculation of diluted earnings (loss) per share, because their inclusion would be anti-dilutive: | | | | | | | | | | | | | | | | | | | | | | | |
| Three Months Ended September 30, | | Nine Months Ended September 30, |
| 2023 | | 2022 | | 2023 | | 2022 |
| (unaudited) | | (unaudited) |
| | | | | | | |
2023 Notes | — | | | 6,783,936 | | | 2,261,312 | | | — | |
| | | | | | | |
Stock options, RSUs, PSUs | 411,506 | | | 792,904 | | | 486,080 | | | 470,822 | |
The following table sets forth the computation of basic and diluted earnings (loss) per share for the three and nine months ended September 30, 2023 and 2022 under the if-converted method (dollars in thousands, except share and per share amounts):
| | | | | | | | | | | | | | | | | | | | | | | |
| Three Months Ended September 30, | | Nine Months Ended September 30, |
| 2023 | | 2022 | | 2023 | | 2022 |
| (unaudited) | | (unaudited) |
Numerator: | | | | | | | |
Net earnings (loss) | $ | (15,976) | | | $ | 1,749 | | | $ | 141 | | | $ | 35,230 | |
After-tax interest expense for 2023 Notes | — | | | — | | | — | | | 2,664 | |
Numerator for dilutive earnings (loss) per share | $ | (15,976) | | | $ | 1,749 | | | $ | 141 | | | $ | 37,894 | |
Denominator: | | | | | | | |
Weighted average shares outstanding, basic | 54,608,963 | | | 53,789,674 | | | 54,498,687 | | | 53,517,838 | |
Effect of dilutive securities: | | | | | | | |
Stock options, RSUs and SARs | — | | | 1,245,164 | | | 1,076,235 | | | 1,241,347 | |
Convertible notes | — | | | — | | | — | | | 6,783,936 | |
Weighted average shares outstanding, diluted | 54,608,963 | | | 55,034,838 | | | 55,574,922 | | | 61,543,121 | |
| | | | | | | |
Earnings (loss) per share, basic | $ | (0.29) | | | $ | 0.03 | | | $ | 0.00 | | | $ | 0.66 | |
Earnings (loss) per share, diluted | $ | (0.29) | | | $ | 0.03 | | | $ | 0.00 | | | $ | 0.62 | |
11. Income Tax Expense (Benefit)
The following table provides information regarding the Company’s income tax expense (benefit) for the three and nine months ended September 30, 2023 and 2022 (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | |
| Three Months Ended September 30, | | Nine Months Ended September 30, |
| 2023 | | 2022 | | 2023 | | 2022 |
| (unaudited) | | (unaudited) |
Income tax expense (benefit) | $ | 25,865 | | | $ | (2,193) | | | $ | 1,638 | | | $ | (9,627) | |
Effective tax rate | 261.6 | % | | 493.9 | % | | 92.1 | % | | (37.6) | % |
Income tax expense was $25.9 million for the three months ended September 30, 2023, as compared to income tax benefit of $2.2 million for the same period in the prior year. The change was primarily due to the larger pretax income in the third quarter of 2023. Income tax expense was $1.6 million for the nine months ended September 30, 2023, as compared to income tax benefit of $9.6 million for the same period in the prior year. The change was primarily due to certain tax benefits recognized with certain reorganization activities that occurred during the first quarter of 2022.
The change in the effective tax rates for both the three months ended September 30, 2023 and nine months ended September 30, 2023, as compared to the same periods in prior year, were primarily due to lower pretax earnings forecasted for 2023. ASC 740, Income Taxes (ASC 740), requires an estimate of the annual effective income tax rate for the full year and apply it to pretax income (loss) for each interim period, taking into account year-to-date amounts and projected results for the full year. The annual forecasted earnings represent the Company's best estimate as of September 30, 2023 and is subject to changes, which could have a material impact on the effective tax rate in subsequent periods.
12. Leases
Operating lease assets and lease liabilities as reported on the unaudited condensed consolidated balance sheets are as follows (dollars in thousands):
| | | | | | | | | | | | | | | | | |
| Balance Sheet Classification | | September 30, 2023 | | December 31, 2022 |
| | | (unaudited) | | |
Assets | | | | | |
Operating lease assets | Other assets | | $ | 29,456 | | | $ | 28,904 | |
Total lease assets | | | $ | 29,456 | | | $ | 28,904 | |
| | | | | |
Liabilities | | | | | |
Operating lease liabilities, current portion | Accounts payable and accrued liabilities | | $ | 8,480 | | | $ | 6,791 | |
Operating lease liabilities, long-term | Operating lease liabilities, long-term | | 33,841 | | | 35,998 | |
Total lease liabilities | | | $ | 42,321 | | | $ | 42,789 | |
13. Composition of Other Balance Sheet Items
The following details the composition of other balance sheet items (dollars in thousands for amounts in tables):
Accounts Receivables, Net
As of September 30, 2023 and December 31, 2022, the Company has reduced accounts receivable by approximately $10.8 million and $13.0 million, respectively. Prompt pay discount and contractual service fees, which were originally recorded as a reduction to revenues, represents estimated amounts not expected to be paid by our customers. The Company's customers are primarily pharmaceutical wholesalers and distributors and specialty pharmacies.
Inventories
| | | | | | | | | | | |
| September 30, 2023 | | December 31, 2022 |
| (unaudited) | | |
Raw materials | $ | 21,556 | | | $ | 24,820 | |
Work in process | 26,966 | | | 31,710 | |
Finished goods | 34,958 | | | 35,011 | |
Total | $ | 83,480 | | | $ | 91,541 | |
Property and Equipment
| | | | | | | | | | | |
| September 30, 2023 | | December 31, 2022 |
| (unaudited) | | |
Lab equipment and furniture | $ | 12,620 | | | $ | 12,127 | |
Leasehold improvements | 14,023 | | | 14,023 | |
Software | 883 | | | 883 | |
Computer equipment | 1,078 | | | 983 | |
Construction-in-progress | — | | | 206 | |
| 28,604 | | | 28,222 | |
Less accumulated depreciation and amortization | (14,916) | | | (13,049) | |
Property and equipment, net | $ | 13,688 | | | $ | 15,173 | |
Depreciation and amortization expense on property and equipment was approximately $0.6 million and $1.9 million for the three and nine months ended September 30, 2023, and approximately $0.8 million and $2.2 million for the three and nine months ended September 30, 2022, respectively.
Accounts Payable and Accrued Liabilities
| | | | | | | | | | | |
| September 30, 2023 | | December 31, 2022 |
| (unaudited) | | |
Accounts payable | $ | 3,389 | | | $ | 10,543 | |
Accrued compensation, benefits, & related accruals | 19,025 | | | 16,963 | |
Accrued sales & marketing | 11,656 | | | 16,783 | |
Accrued R&D expenses | 9,659 | | | 7,490 | |
Accrued manufacturing expenses | 9,569 | | | 15,216 | |
Accrued royalties (1) | 8,852 | | | 12,022 | |
Operating lease liabilities, current portion (2) | 8,480 | | | 6,791 | |
Other accrued expenses | 7,841 | | | 10,534 | |
Total | $ | 78,471 | | | $ | 96,342 | |
_______________________________
(1) Refer to Note 15, Commitments and Contingencies.
(2) Refer to Note 12, Leases.
Accrued Product Returns and Rebates
| | | | | | | | | | | |
| September 30, 2023 | | December 31, 2022 |
| (unaudited) | | |
Accrued product rebates | $ | 108,129 | | | $ | 106,657 | |
Accrued product returns | 54,344 | | | 45,008 | |
Total | $ | 162,473 | | | $ | 151,665 | |
14. Interest Expense
The following details the composition of interest expense (dollars in thousands):
| | | | | | | | | | | | | | | | | | | | | | | |
| Three Months Ended September 30, | | Nine Months Ended September 30, |
| 2023 | | 2022 | | 2023 | | 2022 |
| (unaudited) | | (unaudited) |
Interest expense | $ | — | | | $ | (629) | | | $ | (1,321) | | | $ | (1,906) | |
Noncash interest expense on nonrecourse liability related to sale of future royalties | — | | | (566) | | | (562) | | | (1,988) | |
Noncash interest expense on debt | — | | | (529) | | | (532) | | | (1,582) | |
Total | $ | — | | | $ | (1,724) | | | $ | (2,415) | | | $ | (5,476) | |
Noncash interest expense on debt is related to amortization of deferred financing costs on the 2023 Notes. The Company fully amortized the deferred financing costs on the 2023 Notes in the first quarter of 2023.
15. Commitments and Contingencies
Product Licenses
The Company has obtained exclusive licenses from third parties for proprietary rights to support the product candidates in the Company's CNS portfolio. Under these license agreements, the Company may be required to pay certain amounts upon the achievement of defined milestones. If these products are ultimately commercialized, the Company is also obligated to pay royalties to third parties, computed as a percentage of net product sales, for each respective product under a license agreement.
Through the USWM Acquisition, the Company acquired licensing agreements with other pharmaceutical companies for APOKYN, XADAGO, and MYOBLOC. The Company is obligated to pay royalties to third parties, computed as a percentage of net product sales, for each of the products under the respective license agreements. The royalty expense incurred for these acquired products is recognized as Cost of goods sold in the unaudited condensed consolidated statements of earnings (loss).
Royalty Agreement
In the third quarter of 2014, the Company received $30 million pursuant to a Royalty Interest Acquisition Agreement related to the purchase by HC Royalty of certain of the Company's rights under the Company's agreement with United Therapeutics related to the commercialization of Orenitram (treprostinil) Extended-Release Tablets. Full ownership of the royalty rights have reverted back to the Company as the cumulative payment threshold has been reached as of June 30, 2023 (see Note 3, Disaggregated Revenues).
As of December 31, 2022, the nonrecourse liability related to the sale of future royalties was $6.0 million and was included in Other current liabilities as reported on the condensed consolidated balance sheet.
USWM Enterprise Commitments Assumed
As part of the USWM Acquisition, the Company assumed the remaining commitments of USWM Enterprises and its subsidiaries, which are discussed below.
The Company assumed the annual minimum purchase requirement of MYOBLOC, amounting to an estimated €3.9 million annually, under the contract manufacturing agreement with Merz for manufacture and supply.
MDD US Operations, LLC (formerly US WorldMeds, LLC) and its subsidiary, Solstice Neurosciences, LLC (US) (collectively, the MDD Subsidiaries) entered into a Corporate Integrity Agreement (CIA) with the Office of Inspector General of the U.S. Department of Health and Human Services which was effective in April 2019. Under the CIA, the MDD Subsidiaries agreed to and paid $17.5 million to resolve U.S. Department of Justice allegations that it violated the False Claims Act and committed to the establishment and ongoing maintenance of an effective compliance program. The fine was paid by the MDD Subsidiaries prior to closing of the USWM Acquisition. As part of the USWM Acquisition, the Company assumed the obligations of the CIA and could become liable for payment of certain stipulated monetary penalties in the event of any CIA violations. In addition, the Company will continue to maintain a broad array of processes, policies and procedures necessary to comply with the
CIA through March 2024.
Data Breach-related Contingency
On November 24, 2021, the Company announced that we were the target of a ransomware attack. The attack had no significant impact on our business and did not cause any long-term disruption to our operations. Based on its internal investigation, the Company believes the criminal ransomware groups ("criminal groups") copied certain data from our systems, encrypted certain data on the Company's systems, and then deployed malware designed to impede access to our systems. Thereafter the criminal groups contacted the Company and threatened to publish certain data copied from the Company's systems. Upon detection of the ransomware attack, the Company notified government authorities, engaged third-party cybersecurity experts through our outside counsel, and commenced its recovery process. The Company maintains redundant off-site data backups, which were verified to have not been compromised by the ransomware attack and were utilized to restore the data encrypted by the criminal groups. In the fourth quarter of 2021, the Company had successfully recovered the impacted files and took additional steps designed to further protect its networks and files.
Furthermore, while the Company has not been the subject of any legal proceedings involving the attack, the likelihood that the Company could be the subject of claims from persons alleging they suffered damages from the incident, or actions by governmental authorities is possible, but the amount of such fines, penalties or costs, if any, cannot be estimated at this time. The Company continues to monitor the situation.
Claims and Litigation
From time to time, the Company may be involved in various claims, litigation and legal proceedings. These matters may involve patent litigation, product liability and other product-related litigation, commercial and other matters, and government investigations, among others. On a quarterly basis, the Company reviews the status of each significant matter and assesses its potential financial exposure. If the potential loss from any claim, asserted or unasserted, or legal proceeding is considered probable and the amount can be reasonably estimated, the Company will accrue a liability for the estimated loss. Because of uncertainties related to claims, legal proceedings and litigation, accruals will be based on the Company's best estimates based on available information. The Company does not believe that any of these matters will have a material adverse effect on our financial position. The Company may reassess the potential liability related to these matters and may revise these estimates. The process of resolving matters through litigation or other means is inherently uncertain and it is possible that an unfavorable resolution of these matters will adversely affect the Company, its results of operations, financial condition and cash flows.
NAMENDA XR/Namzaric Qui Tam Litigation
On April 1, 2019, Adamas was served with a complaint filed in the United States District Court for the Northern District of California (the District Court) (Case No. 3:18-cv-03018-JCS) against it and several Allergan entities alleging violations of federal and state false claims acts (FCA) in connection with the commercialization of NAMENDA XR and Namzaric by Allergan. The lawsuit is a qui tam complaint brought by an individual, asserting rights of the federal government and various state governments. The lawsuit was originally filed in May 2018 under seal, and Adamas became aware of the lawsuit when it was served. The complaint alleges that patents held by Allergan and Adamas covering NAMENDA XR and Namzaric were procured through fraud on the United States Patent and Trademark Office and that these patents were asserted against potential generic manufacturers of NAMENDA XR and Namzaric to prevent the generic manufacturers from entering the market, thereby wrongfully excluding generic competition resulting in artificially high price being charged to government payors. Adamas' patents in question were licensed exclusively to Forest Laboratories Holdings Limited. The complaint includes a claim for damages of "potentially more than $2.5 billion dollars," treble damages and statutory penalties. To date the federal and state governments have declined to intervene in this action. This case is currently stayed pending Adamas's and Allergan's interlocutory appeal of the District Court's December 11, 2020 order denying Adamas's and Allergan's motion to dismiss the complaint. The appeal was heard by the United States Court of Appeals for the Ninth Circuit (Case No. 21-80005). Argument was held on January 10, 2022. On August 25, 2022, the Ninth Circuit sided with the defendants by reversing the District Court’s public disclosure bar rulings and remanding the case back to the District Court to decide certain issues in the first instance. On October 11, 2022, the plaintiff filed a petition for rehearing with the Ninth Circuit which was denied on November 3, 2022. On December 23, 2022, the defendants filed renewed motions to dismiss directed to the remaining unresolved issue. On March 20, 2023, the District Court entered an order and final judgment dismissing with prejudice Silbersher’s Federal False Claims Act claim while declining to exercise supplemental jurisdiction over the state false claims act claims which were dismissed without prejudice. On April 19, 2023, the plaintiff appealed the District Court's dismissal of the Federal False Claims Act claim.
APOKYN Litigation
On October 3, 2022, Sage Chemical, Inc. and TruPharma, LLC filed a lawsuit in the United States District Court for the District of Delaware (Case No.22-cv-1302) alleging that Supernus Pharmaceuticals, Inc., Britannia Pharmaceuticals Limited, and US WorldMeds Partners, LLC violated state and federal antitrust law in connection with APOKYN. On January 10, 2023, the Company filed motions to dismiss all claims. On January 25, 2023, Defendants filed a motion to stay discovery and stay the deadline to submit a proposed scheduling order pending resolutions of Defendants’ motions to dismiss. On March 7, 2023, the Court denied the Company's motion to stay and ordered that the parties commence discovery. On April 10, 2023, the Court issued a scheduling order that provides for a Pretrial Conference on March 7, 2025 and a jury trial beginning on March 24, 2025. Pretrial discovery is ongoing as the date of this letter. The Company intends to defend itself vigorously. However, the Company can offer no assurances that it will be successful in a litigation.
Apotex Settlement and License Agreements
The Company entered into a settlement and license agreements dated June 21, 2023 with Apotex Inc. to settle ongoing patent litigation regarding Apotex ANDA filings seeking approval to market a generic version of the Company's 150mg, 300mg, and 600mg strength Oxtellar XR (extended-release oxcarbazepine) tablets in September 2024, or sooner under certain conditions.
16. Subsequent Events
In October 2023, the Company resubmitted its New Drug Application (NDA) for its apomorphine infusion device (SPN-830) for the continuous treatment of motor fluctuations ("off" episodes) in Parkinson’s disease. In November 2023. the FDA accepted the resubmission of the NDA for SPN-830. The NDA is now considered filed, with a user fee goal date (PDUFA date) of April 5, 2024.
Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations
Management’s Discussion and Analysis of Financial Condition and Results of Operations is intended to help the reader understand the results of operations and the financial condition of Supernus Pharmaceuticals, Inc. The interim condensed consolidated financial statements included in this report and this Management’s Discussion and Analysis of Financial Condition and Results of Operations should be read in conjunction with our audited consolidated financial statements and notes thereto for the year ended December 31, 2022 and the related Management’s Discussion and Analysis of Financial Condition and Results of Operations, both of which are contained in our Annual Report on Form 10-K, filed with the Securities and Exchange Commission on March 9, 2023.
In addition to historical information, this Quarterly Report on Form 10-Q contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are intended to be covered by the safe harbors created thereby. These forward-looking statements may include declarations regarding the Company’s belief or current expectations of management, such as statements including the words “budgeted,” “anticipate,” “project,” “forecast,” “estimate,” “expect,” “may,” “believe,” “potential,” and similar statements or expressions, which are intended to be among the statements that are forward-looking statements, as such statements reflect the reality of risk and uncertainty that is inherent in our business. Actual results may differ materially from those expressed or implied by such forward-looking statements. Readers are cautioned not to place undue reliance on these forward-looking statements, which are made as of the date this report was filed with the Securities and Exchange Commission. Our actual results and the timing of events could differ materially from those discussed in our forward-looking statements because of many factors, including those set forth under the “Risk Factors” section of our Annual Report on Form 10-K and elsewhere in this report as well as in other reports and documents we file with the Securities and Exchange Commission from time to time. Except as required by law, we undertake no obligation to update any forward-looking statements to reflect events or circumstances occurring after the date of this Quarterly Report on Form 10-Q.
Unless the content requires otherwise, the words "Supernus," "we," "our" and "the Company" refer to Supernus Pharmaceuticals, Inc. and/or one or more of its subsidiaries, as the case may be. These terms are used solely for the convenience of the reader. Supernus Pharmaceuticals, Inc. and each of its subsidiaries are distinct legal entities. For example, MDD US Operations, LLC, a wholly-owned indirect subsidiary of Supernus Pharmaceuticals, Inc., is the exclusive licensee and distributor of APOKYN in the United States and its territories. Adamas Operations, LLC, a wholly-owned indirect subsidiary of Supernus Pharmaceuticals, Inc., wholly owns the patents and patent applications related to GOCOVRI and Osmolex ER and has a license agreement with Supernus Pharmaceuticals, Inc., granting Supernus Pharmaceuticals, Inc. rights to market and sell GOCOVRI and Osmolex ER.
Solely for convenience, in this Quarterly Report on Form 10-Q, the trade names are referred to without the TM symbols and the trademark registrations are referred to without the circled R, but such references should not be construed as any indicator that the Company will not assert, to the fullest extent under applicable law, our rights thereto.
Overview
We are a biopharmaceutical company focused on developing and commercializing products for the treatment of central nervous system (CNS) diseases. Our diverse neuroscience portfolio includes approved treatments for epilepsy, migraine, attention-deficit hyperactivity disorder (ADHD), hypomobility in Parkinson’s Disease (PD), cervical dystonia, chronic sialorrhea, dyskinesia in PD patients receiving levodopa-based therapy, and drug-induced extrapyramidal reactions in adult patients. We are developing a broad range of novel CNS product candidates including new potential treatments for hypomobility in PD, epilepsy, depression, and other CNS disorders.
Commercial Products
•Qelbree® (viloxazine extended-release capsules) is a novel non-stimulant product indicated for the treatment of ADHD in adults and pediatric patients 6 years and older. The United States Food and Drug Administration (FDA) approved Qelbree for the treatment of ADHD in pediatric patients 6 to 17 years of age in April 2021, and in adult patients in April 2022. The Company launched Qelbree for pediatric patients in May 2021 and for adult patients in May 2022 in the United States (U.S.).
•GOCOVRI® (amantadine) extended-release capsules is the first and only FDA approved medicine indicated for the treatment of dyskinesia in patients with PD receiving levodopa-based therapy, with or without concomitant dopaminergic medications, and as an adjunctive treatment to levodopa/carbidopa with PD experiencing "off" episodes.
•Trokendi XR® (topiramate) is the first once-daily extended-release topiramate product indicated for the treatment of epilepsy in patients 6 years of age and older in the U.S. market. It is also indicated for the prophylaxis of migraine headache in adults and adolescents 12 years and older.
•Oxtellar XR® (oxcarbazepine) is indicated as therapy for the treatment of partial onset seizures in patients 6 years of age and older. It is also the first once-daily extended-release oxcarbazepine product indicated for the treatment of epilepsy in the U.S. market.
•APOKYN® (apomorphine hydrochloride injection) is a product indicated for the acute, intermittent treatment of hypomobility, "off" episodes ("end-of-dose wearing off" and unpredictable "on/off" episodes) in patients with advanced PD.
•XADAGO® (safinamide) is a once-daily product indicated as adjunctive treatment to levodopa/carbidopa in patients with PD experiencing "off" episodes.
•Osmolex ER® (amantadine) extended-release tablets is for the treatment of PD and drug-induced extrapyramidal reactions in adult patients.
•MYOBLOC® (rimabotulinumtoxinB injection) is a product indicated for the treatment of cervical dystonia and chronic sialorrhea in adults. It is the only botulinum toxin type B available on the market.
Research and Development
We are committed to the development of innovative product candidates in neurology and psychiatry, including the following: SPN-830 (apomorphine infusion device) for treatment of PD
SPN-830 is a late-stage drug/device combination product candidate for the continuous treatment of motor fluctuations ("off" episodes) in PD patients that are not adequately controlled with oral levodopa and one or more adjunct PD medications. If approved, it would be the only continuous infusion of apomorphine available in the U.S. and an important step for PD patients that would have otherwise been candidates for potentially invasive surgical procedures, such as deep brain stimulation. Continuous slow infusion may also limit some of the side effects of a bolus injection of apomorphine.
In December 2021, we resubmitted the New Drug Application (NDA) to the FDA. In February 2022, we received a notice from the FDA that the resubmission of the NDA for SPN-830 was considered as a Standard Review and was assigned a PDUFA target action date in early October 2022. In October 2022, the FDA issued a Complete Response Letter (CRL) regarding the NDA for SPN-830. The CRL requires additional information and analysis related to the infusion device and drug product across several areas of the NDA including, but not limited to, labeling, product quality and manufacturing, device performance and risk analysis. In addition, the FDA mentions that approval of the NDA requires inspections that could not be completed in a timely manner due to COVID-19 travel restrictions. The CRL does not request additional efficacy and safety clinical studies. The FDA has made an initial determination that the amendment to the Company’s application in response to the CRL will be subject to a Class 2, or six-month, review timeline. In April 2023, the Company met with the FDA to discuss the CRL. In October 2023, the Company resubmitted the NDA for SPN-830. Refer to discussion under the Operational Highlights section below for a further regulatory update.
SPN-820 – Novel first-in-class molecule that increases mTORC1 mediated synaptic function for depression
SPN-820 is a first-in-class, orally active small molecule that increases the brain mechanistic target of rapamycin
complex 1 (mTORC1) mediated synaptic function intracellularly. SPN-820 does not bind to or modulate any cell surface receptors and therefore is unlikely to have abuse potential given lack of binding to targets implicated in drug abuse. In addition, unlike leucine, it is not incorporated into proteins during protein synthesis, and therefore, it is more available at the target site in the brain than leucine.
SPN-817 – Novel first-in-class highly selective AChE inhibitor for epilepsy
SPN-817 represents a novel mechanism of action (MOA) for an anticonvulsant. SPN-817 is a novel synthetic form of
huperzine A, a first in class, highly selective acetylcholinesterase (AChE) inhibitor, with pharmacological activities in CNS conditions such as focal epilepsy. The development will initially focus on the drug's anticonvulsant activity, which has been shown in preclinical models to be effective for the treatment of epilepsy. SPN-817 is in clinical development and has received Orphan Drug designation for several epilepsy indications from the FDA.
Operational Highlights
Qelbree Update
•Total IQVIA prescriptions were 163,344 in the third quarter of 2023, an increase of 73% compared to the same period last year and 12% compared to the second quarter of 2023.
•Qelbree continues to expand its base of prescribers, with approximately 24,189 prescribers in the third quarter of 2023, up from 21,291 prescribers in the second quarter of 2023.
•The Company presented new data at Psych Congress 2023 in September showing improved efficacy in children ages 6 years and older with ADHD when Qelbree is administered with stimulants, as well as in adults with ADHD who undergo long-term treatment with Qelbree.
Product Pipeline Update
SPN-830 (apomorphine infusion device) - Continuous treatment of motor fluctuations (“off” episodes) in Parkinson's Disease (PD)
•In November 2023, the FDA accepted the resubmission of the NDA for SPN-830. The resubmission is now considered filed, with a user fee goal date (PDUFA date) of April 5, 2024.
SPN-820 - Novel first-in-class activator of mTORC1 for the treatment of depression
•The Phase IIb multi-center randomized double-blind placebo-controlled parallel design study of SPN-820 in adults with treatment-resistant depression is ongoing. The study will examine the efficacy and safety of SPN-820 over a course of five weeks of treatment in approximately 268 patients in up to 50 clinical sites. The primary outcome measure is the change from baseline to end of treatment period on the Montgomery-Asberg Depression Rating Scale (MADRS) Total Score. Topline data from the Phase IIb trial is expected in 2025.
•The Company plans to initiate a Phase II open-label study in approximately 40 subjects with major depressive disorder (MDD) before year-end 2023. The primary objective of the study is to assess efficacy in MDD, as well as onset of efficacy.
SPN-817 – Novel first-in-class selective acetylcholinesterase (AChE) inhibitor for the treatment of epilepsy
•An open-label Phase IIa clinical study of SPN-817 for treatment-resistant seizures is ongoing. The study is examining the safety and tolerability of SPN-817 as adjunctive therapy in adult patients with treatment-resistant seizures, as well as assessing efficacy. The Company expects topline results from the Phase IIa study in the first half of 2024.
•The Company expects to initiate a Phase IIb randomized, double-blind, placebo-controlled study in approximately 436 patients with treatment-resistant focal seizures in the first half of 2024. The primary endpoint is change from baseline in focal seizure frequency per 28 days. Topline results from the Phase IIb study are expected in 2026.
SPN-443 – Novel stimulant for the treatment of ADHD/CNS
•The Company is planning in 2024 to initiate a Phase I single dose study in approximately 24 healthy adults following submission of an investigational new drug application. The primary objective of the study is to assess safety and tolerability.
Critical Accounting Policies and the Use of Estimates
A summary of our significant accounting policies is included in Note 2, Summary of Significant Accounting Policies of our audited consolidated financial statements included in the Annual Report on Form 10-K for the year ended December 31, 2022. There were no significant changes to the disclosures with respect to our critical accounting policies in our Annual Report on Form 10-K for the year ended December 31, 2022.
Results of Operations
Comparison of the Three and Nine Months ended September 30, 2023 and 2022
Revenues
Revenues consist primarily of net product sales of our commercial products in the U.S., supplemented by royalty revenues from our collaborative licensing arrangements. The following table provides information regarding our revenues during the three and nine months ended months ended September 30, 2023 and 2022 (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Three Months Ended September 30, | | Change | | Nine Months Ended September 30, | | Change |
| 2023 | | 2022 | | Amount | | Percent | | 2023 | | 2022 | | Amount | | Percent |
Net product sales | | | | | | | | | | | | | | | |
Qelbree | $ | 37,081 | | | $ | 18,326 | | | $ | 18,755 | | | 102 | % | | $ | 93,840 | | | $ | 37,708 | | | $ | 56,132 | | | 149 | % |
GOCOVRI | 32,889 | | | 27,878 | | | 5,011 | | | 18 | % | | 87,650 | | | 75,179 | | | 12,471 | | | 17 | % |
Oxtellar XR | 29,644 | | | 30,528 | | | (884) | | | (3) | % | | 82,359 | | | 88,007 | | | (5,648) | | | (6) | % |
Trokendi XR | 20,625 | | | 69,599 | | | (48,974) | | | (70) | % | | 74,734 | | | 204,033 | | | (129,299) | | | (63) | % |
APOKYN | 21,510 | | | 18,261 | | | 3,249 | | | 18 | % | | 56,324 | | | 57,156 | | | (832) | | | (1) | % |
Other(1) | 7,255 | | | 8,132 | | | (877) | | | (11) | % | | 23,008 | | | 23,564 | | | (556) | | | (2) | % |
Total net product sales | $ | 149,004 | | | $ | 172,724 | | | $ | (23,720) | | | (14) | % | | $ | 417,915 | | | $ | 485,647 | | | $ | (67,732) | | | (14) | % |
Royalty revenues | 4,876 | | | 4,629 | | | 247 | | | 5 | % | | 25,292 | | | 14,263 | | | 11,029 | | | 77 | % |
Total revenues | $ | 153,880 | | | $ | 177,353 | | | $ | (23,473) | | | (13) | % | | $ | 443,207 | | | $ | 499,910 | | | $ | (56,703) | | | (11) | % |
___________________________________________ (1) Includes net product sales of MYOBLOC, XADAGO and Osmolex ER.
Total net product sales decreased by $23.7 million and $67.7 million for the three and nine months ended September 30, 2023, as compared to the same periods in 2022, primarily due to the decline in net product sales of Trokendi XR which was partially offset by the increase in net product sales from Qelbree and GOCOVRI.
Qelbree net product sales increased by $18.8 million and $56.1 million for the three and nine months ended September 30, 2023 due to favorable unit prescription volume growth. The Company launched Qelbree for pediatric patients in May 2021 and for adult patients in May 2022 in the U.S. Trokendi XR net product sales decreased for the three and nine months ended September 30, 2023, as compared to the same periods in 2022 due to the loss of exclusivity with generics entering the market in January 2023.
Sales Deductions and Related Accruals
We record accrued product returns and accrued product rebates as current liabilities in Accrued product returns and rebates, on our condensed consolidated balance sheets. We record sales discounts as a reduction against Accounts receivable, net on the condensed consolidated balance sheets. Both amounts are generally affected by changes in gross product sales, changes in the provision for net product sales deductions, and the timing of payments/credits.
The following table provides a summary of activity with respect to accrued product returns and rebates during the periods indicated (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | |
| Accrued Product Returns and Rebates | | | | |
| Product Returns | | Product Rebates | | Allowance for Sales Discounts | | Total |
Balance at December 31, 2022 | $ | 45,008 | | | $ | 106,657 | | | $ | 12,995 | | | $ | 164,660 | |
Provision | | | | | | | |
Provision for current year sales | 17,484 | | | 310,166 | | | 48,766 | | | 376,416 | |
Adjustments relating to prior year sales | (52) | | | 1,657 | | | 32 | | | 1,637 | |
Total provision | $ | 17,432 | | | $ | 311,823 | | | $ | 48,798 | | | $ | 378,053 | |
Less: Actual payments/credits | (8,096) | | | (310,351) | | | (50,960) | | | (369,407) | |
Balance at September 30, 2023 | $ | 54,344 | | | $ | 108,129 | | | $ | 10,833 | | | $ | 173,306 | |
| | | | | | | | | | | | | | | | | | | | | | | |
| Accrued Product Returns and Rebates | | | | |
| Product Returns | | Product Rebates | | Allowance for Sales Discounts | | Total |
Balance at December 31, 2021 | $ | 35,127 | | | $ | 97,597 | | | $ | 13,537 | | | $ | 146,261 | |
Provision | | | | | | | |
Provision for current year sales | 13,846 | | | 321,860 | | | 55,693 | | | 391,399 | |
Adjustments relating to prior year sales | (3,225) | | | 31 | | | (3) | | | (3,197) | |
Total provision | $ | 10,621 | | | $ | 321,891 | | | $ | 55,690 | | | $ | 388,202 | |
Less: Actual payments/credits | (6,440) | | | (300,326) | | | (56,447) | | | (363,213) | |
Balance at September 30, 2022 | $ | 39,308 | | | $ | 119,162 | | | $ | 12,780 | | | $ | 171,250 | |
Accrued Product Returns and Rebates
The accrued product returns balance increased from $39.3 million as of September 30, 2022 to $54.3 million as of September 30, 2023 principally due to the timing of related return activity and an increase in provision for product returns primarily related to Qelbree.
The accrued product rebates balance decreased from $119.2 million as of September 30, 2022 to $108.1 million as of September 30, 2023 due to lower gross sales primarily relating to the loss of exclusivity on Trokendi XR and timing of payments.
Provision for Product Returns and Rebates
The provision for product returns increased from $10.6 million for the nine months ended September 30, 2022 to $17.4 million for the nine months ended September 30, 2023. The increase was primarily attributable to an increase in volume of products sold with the launch of Qelbree for adults in 2022, partially offset by lower sales of Trokendi XR.
The provision for product rebates decreased from $321.9 million for the nine months ended September 30, 2022 to $311.8 million for nine months ended September 30, 2023. The decrease was primarily attributable to lower Trokendi XR sales partially offset by higher Qelbree sales.
Royalty Revenues
Royalty revenues were $4.9 million and $4.6 million for the three months ended September 30, 2023 and 2022, respectively. Royalty revenues were $25.3 million and $14.3 million for the nine months ended September 30, 2023 and 2022, respectively. The increase was primarily due to royalties on generic Trokendi XR for the nine months ended September 30, 2023. The Company entered into settlement agreements on Trokendi XR that allowed third party generics to enter the market beginning January 1, 2023 and required them to pay royalties to the Company.
Cost of Goods Sold
Cost of goods sold was $19.6 million and $25.9 million for the three months ended September 30, 2023 and 2022, respectively. The decrease was primarily due to higher reserves in 2022 for GOCOVRI. Cost of goods sold was $64.2 million and $64.3 million for the nine months ended September 30, 2023 and 2022, respectively. The $0.1 million increase was primarily due to higher Qelbree costs in 2023 offset by higher GOCOVRI and Qelbree inventory reserve in 2022.
Research and Development Expenses
R&D expenses were $22.7 million and $19.6 million for the three months ended September 30, 2023 and 2022, respectively. R&D expenses were $68.2 million and $56.8 million for the nine months ended September 30, 2023 and 2022, respectively. The increase for both periods was primarily due to increased clinical program costs on SPN-817 and SPN-820 and increased manufacturing costs for our product candidates.
Selling, General and Administrative Expenses
The following table provides information regarding our selling, general and administrative (SG&A) expenses during the periods indicated (dollars in thousands):
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Three Months Ended September 30, | | Change | | Nine Months Ended September 30, | | Change |
| 2023 | | 2022 | | Amount | | Percent | | 2023 | | 2022 | | Amount | | Percent |
Selling and marketing | $ | 56,785 | | | $ | 85,704 | | | $ | (28,919) | | | (34)% | | $ | 173,909 | | | $ | 219,798 | | | $ | (45,889) | | | (21)% |
General and administrative | 25,915 | | | 26,610 | | | (695) | | | (3)% | | 81,170 | | | 83,451 | | | (2,281) | | | (3)% |
Total | $ | 82,700 | | | $ | 112,314 | | | $ | (29,614) | | | (26)% | | $ | 255,079 | | | $ | 303,249 | | | $ | (48,170) | | | (16)% |
Selling, general and administrative expenses decreased by 26% to $82.7 million for the three months ended September 30, 2023 and by 16% to $255.1 million for the nine months ended September 30, 2023. The decrease in selling and marketing expenses was primarily attributable to activities to support the launch of Qelbree to the adult population and the Qelbree direct-to-consumer campaign, which substantially occurred in the third quarter of 2022. The decrease in general and administrative expenses was primarily due to higher professional and consulting costs to support finance and information and technology operations in 2022, which was partially offset by higher legal costs and share-based compensation expense in 2023.
Amortization of Intangible Assets
Amortization of intangible assets was $21.2 million and $20.6 million for the three months ended September 30, 2023 and 2022, respectively. Amortization of intangible assets was $61.3 million and $61.9 million for the nine months ended September 30, 2023 and 2022, respectively.
Contingent Consideration (Gain) Expense
Contingent consideration was a gain of $0.5 million and an expense of $0.5 million for the three months ended September 30, 2023 and 2022, respectively. Contingent consideration was a gain of $1.3 million and an expense of $1.9 million for the nine months ended September 30, 2023 and 2022, respectively. The contingent consideration gain was primarily driven by the change in estimated fair value of sales-based milestones associated with the Adamas Acquisition.
Other Income (Expense)
Other income (expense) was income of $1.8 million and $1.1 million for the three months ended September 30, 2023 and 2022, respectively.
Other income (expense) was income of $6.1 million and $13.8 million for the nine months ended September 30, 2023 and 2022, respectively. The $7.7 million decrease in other income was primarily due to the $12.9 million gain associated with the Navitor investment for the three months ended March 31, 2022, offset by a decrease of $3.1 million in interest expense due to the repayment of the 2023 Notes in the second quarter of 2023.
Income Tax Expense (Benefit)
Income tax expense was $25.9 million for the three months ended September 30, 2023 as compared to income tax benefit of $2.2 million for the same period in the prior year. The change was primarily due to the larger pretax income in the third quarter of 2023. Income tax expense was $1.6 million for the nine months ended September 30, 2023 as compared to income tax benefit of $9.6 million for the same period in the prior year. The change was primarily due to certain tax benefits recognized with certain reorganization activities that occurred during the first quarter of 2022.
The change in the effective tax rates for both the three months ended September 30, 2023 and nine months ended September 30, 2023, as compared to the same periods in prior year, were primarily due to lower pretax earnings forecasted for 2023. ASC 740, Income Taxes (ASC 740), requires an estimate of the annual effective income tax rate for the full year and apply it to pretax income (loss) for each interim period, taking into account year-to-date amounts and projected results for the full year. The annual forecasted earnings represent the Company's best estimate as of September 30, 2023 and is subject to changes, which could have a material impact on the effective tax rate in subsequent periods.
Financial Condition, Liquidity and Capital Resources
We have financed our operations primarily with cash generated from product sales, supplemented by revenues from royalty and licensing arrangements, as well as proceeds from the sale of equity and debt securities. Continued cash generation is highly dependent on the success of our commercial products, as well as the success of our product candidates if approved by the FDA. While we expect continued profitability in future years, we anticipate there may be significant variability from year to year in the level of our profits particularly due to the commercial launch of Qelbree and the future commercial launch of SPN-830
(apomorphine infusion device), if approved by the FDA; continued market and payor pressures for our commercial products; the unfavorable impact of the loss of patent exclusivity for Trokendi XR in January 2023; and the likely unfavorable impact of the upcoming loss of patent exclusivity of Oxtellar XR in September 2024, or sooner under certain conditions.
The Company believes its balances of cash, cash equivalents, marketable securities and long-term marketable securities, which totaled $225.3 million as of September 30, 2023, along with cash generated from ongoing operations and continued access to debt markets, will be sufficient to satisfy its cash requirements over the next 12 months and beyond.
We may, from time to time, consider raising additional capital through: new collaborative arrangements; strategic alliances; additional equity and/or debt financings; or financing from other sources, especially in conjunction with opportunistic business development initiatives. We will continue to actively manage our capital structure and to consider all financing opportunities that could strengthen our long-term financial profile. Any such capital raises may or may not be similar to transactions in which we have engaged in the past. There can be no assurance that any such financing opportunities will be available on acceptable terms, if at all.
Cash and Cash Equivalents and Marketable Securities
Cash and cash equivalents, marketable securities, and long-term marketable securities are comprised of the following (dollars in thousands):
| | | | | | | | | | | | | | | | | | | | | | | |
| September 30 | | December 31 | | Change |
| 2023 | | 2022 | | Amount | | Percent |
Cash and cash equivalents | $ | 94,985 | | | $ | 93,120 | | | $ | 1,865 | | | 2% |
Marketable securities | 105,204 | | | 368,214 | | | (263,010) | | | (71)% |
Long-term marketable securities | 25,125 | | | 93,896 | | | (68,771) | | | (73)% |
Total | $ | 225,314 | | | $ | 555,230 | | | $ | (329,916) | | | (59)% |
The decrease is primarily attributable to the repayment of the 2023 Notes on April 1, 2023, partially offset by cash generated from operations.
Cash Flows
Cash flows are comprised of the following (dollars in thousands):
| | | | | | | | | | | | | | | | | |
| Nine Months Ended September 30, | | Change |
| 2023 | | 2022 | | Amount |
Net cash provided by (used in): | | | | | |
Operating activities | $ | 66,127 | | | $ | 89,262 | | | $ | (23,135) | |
Investing activities | 334,710 | | | (167,898) | | | 502,608 | |
Financing activities | (398,972) | | | (13,306) | | | (385,666) | |
Net change in cash and cash equivalents | $ | 1,865 | | | $ | (91,942) | | | $ | 93,807 | |
Cash and cash equivalents at beginning of year | 93,120 | | | 203,434 | | | (110,314) | |
Cash and cash equivalents at end of period | $ | 94,985 | | | $ | 111,492 | | | $ | (16,507) | |
Operating Activities
Net cash provided by operating activities was $66.1 million and $89.3 million for the nine months ended September 30, 2023 and 2022, respectively. The decrease in cash flows provided by operating activities is primarily due to the decrease in earnings as well as changes in working capital which reflects the timing impacts of changes in receivables, inventory, and payables.
Investing Activities
Net cash provided by investing activities was $334.7 million for the nine months ended September 30, 2023 compared to $167.9 million used during the same period in 2022, primarily due to the proceeds from the sale and maturities of investments in marketable securities which were used to pay off the 2023 Notes.
Financing Activities
Net cash used by financing activities were $399.0 million and $13.3 million for the nine months ended September 30, 2023 and 2022, respectively. The increase in cash flows used by financing activities is primarily due to the payment of the total principal amount due on the 2023 Notes. On March 30, 2023, the Company transferred funds totaling $403.8 million to the Trustee (Wilmington Trust) related to the repayment of the 2023 Notes which was reported as restricted cash in the first quarter of 2023. On April 1, 2023, the Company paid the total principal amount of $402.5 million under the 2023 Notes and the remaining outstanding interest due of $1.3 million with the restricted cash. This increase was slightly offset by the payment of $22.9 million for a contingent consideration milestone associated with the USWM Acquisition during the same period in 2022.
Material Cash Requirements
Refer to “Part II, Item 7 — Management’s Discussion and Analysis of Liquidity and Capital Resources”, of our Annual Report on Form 10-K for the year ended December 31, 2022, and Note 15, Commitments and Contingencies, in the Notes to the Condensed Consolidated Financial Statements in Part I, Item 1, Unaudited Condensed Consolidated Financial Statements, of this Quarterly Report on Form 10-Q for the discussion of our contractual obligations.
Recently Issued Accounting Pronouncements
For a discussion of new accounting pronouncements, see Note 2 in the Notes to the Condensed Consolidated Financial Statements in Part I, Item 1, Unaudited Condensed Consolidated Financial Statements, of this Quarterly Report on Form 10-Q.
Item 3. Quantitative and Qualitative Disclosures About Market Risk
The primary objective of our investment activities is to preserve our capital to fund operations and to facilitate business development activities. We also seek to maximize income from our investments without assuming significant interest rate risk, liquidity risk, or risk of default by investing in investment grade securities with maturities of four years or less. Our exposure to market risk is confined to investments in cash and cash equivalents, marketable securities, and long-term marketable securities. As of September 30, 2023, we had cash and cash equivalents, marketable securities, and long-term marketable securities of $225.3 million.
We fully repaid the outstanding principal and interest on the 2023 Notes in April 2023.
We borrowed funds pursuant to our Credit Line in connection with the payment of the 2023 Notes. We fully repaid the outstanding debt under the Credit Line in June 2023. In the future, we may borrow funds under the Credit Line. Variable rate borrowing exposes us to interest rate risk as increases in interest rates would increase our borrowing costs.
Any borrowed funds pursuant to our Credit Line are subject to a collateral maintenance requirement. The Credit Line is secured primarily by our portfolio of marketable securities, which is primarily comprised of corporate and U.S. government agency and municipal debt securities and may fluctuate in value. The fluctuations may be driven by, among other things, changes in interest rates, economic conditions, and other financial conditions as well as idiosyncratic factors related to a security’s issuer. To the extent a fluctuation in value results in the value of the collateral decreasing below the required collateral maintenance requirements we may be required to promptly post additional collateral. Additionally, our Credit Line is an uncommitted facility that may be terminated by the lender at any time. During periods of rapidly changing interest rates, economic conditions or other financial conditions, the Credit Line may be terminated by the lender and/or the lender may declare that any borrowings thereunder are immediately due.
Our cash and cash equivalents consist primarily of cash held at banks and investments in highly liquid financial instruments with an original maturity of three months or less. Our marketable securities, which are reported at fair value, generally consist of money market funds; corporate and municipal debt securities; and other fixed income securities. We place all investments with governmental, industrial, or financial institutions whose debt is rated as investment grade. These securities have maturities of one to four years. Because of the relatively short period that we hold our investments and because we generally hold these securities to maturity, we do not believe that an increase in interest rates would have any significant impact on the realizable value of our investments.
We do not have any currency or other derivative financial instruments other than the outstanding warrants to purchase common stock. The warrants expire in tranches, if unexercised, on or before November 22, 2023. The warrants entitle the holder to one share per warrant. The strike price of the warrants will initially be $80.91 per share of the Company’s common stock, and is subject to adjustment. The warrants could have a dilutive effect with respect to the Company’s common stock, to the extent that the market price per share of the Company’s common stock, as measured under the terms of the Warrant Transactions, exceeds the strike price of the warrants.
We may contract with clinical research organizations (CROs) and investigational sites globally. Currently, we have ongoing clinical trials being conducted outside the U.S. We do not hedge our foreign currency exchange rate risk. Transactions denominated in currencies other than the U.S. dollar are recorded based on exchange rates at the time such transactions arise. As of September 30, 2023 and December 31, 2022, substantially all of our liabilities were denominated in the U.S. dollar.
Inflation generally affects us by increasing our cost of labor and the cost of services provided by our vendors. We do not believe that inflation has had a material effect on our business, financial condition or results of operations. Nonetheless, if our costs were to become subject to significant inflationary pressures, we may not be able to fully offset such higher costs through price increases. Our inability or failure to do so could harm our business, financial condition and results of operations.
Item 4. Controls and Procedures
Evaluation of Disclosure Controls and Procedures
We maintain disclosure controls and procedures required by Rule 13a-15(e) and 15d-15(e) of the Securities Exchange Act of 1934, as amended, or the Exchange Act. Our disclosure controls and procedures are designed to provide reasonable assurance that the information required to be disclosed by us in the reports we file or submit under the Exchange Act has been appropriately recorded, processed, summarized, and reported within the time periods specified in the Securities and Exchange Commission's rules and forms and that such information is accumulated and communicated to our management, including our CEO and CFO, to allow timely decisions regarding required disclosure. We conducted an evaluation of the effectiveness of the design and operation of our disclosure controls and procedures as of September 30, 2023, the end of the period covered by this report. Based on that evaluation, under the supervision and with the participation of our management, including our CEO and CFO, we concluded that our disclosure controls and procedures are effective as of September 30, 2023.
Changes in Internal Control over Financial Reporting
Our management, including our CEO and CFO, evaluated changes in our internal control over financial reporting that occurred during the quarter ended September 30, 2023.
There were no changes in our internal control over financial reporting identified in connection with the evaluation required by paragraph (d) of Exchange Act Rule 13a-15 that occurred during the quarter ended September 30, 2023 that have materially affected or are reasonably likely to materially affect, our internal control over financial reporting.
PART II — OTHER INFORMATION
Item 1. Legal Proceedings
From time to time and in the ordinary course of business, Supernus Pharmaceuticals, Inc. ("Company") and any of its subsidiaries may be subject to various claims, charges and litigation. Parent and any of its subsidiaries may be required to file infringement claims against third parties for the infringement of our patents.
Oxtellar XR®
I. Supernus Pharmaceuticals, Inc. v. Apotex Inc., et al., C.A. No. 20-cv-7870 (MAS)(TJB) (D.N.J.)
The Company received a Paragraph IV Notice Letter from generic drug makers Apotex Inc. and Apotex Corp. (collectively, “Apotex”) dated May 13, 2020, directed to nine of its Oxtellar XR® Orange Book patents. Supernus’s U.S. Patent Nos. 7,722,898; 7,910,131; 8,617,600; 8,821,930; 9,119,791; 9,351,975; 9,370,525; 9,855,278; and 10,220,042 generally cover once-a-day oxcarbazepine formulations and methods of treating seizures using those formulations. The FDA Orange Book lists all nine of the Company’s Oxtellar XR® patents as expiring on April 13, 2027. On June 26, 2020, the Company filed a lawsuit against Apotex alleging infringement of the Company’s nine patents. The Complaint—filed in the U.S. District Court for the District of New Jersey—alleges, inter alia, that Apotex infringed the Company’s Oxtellar XR® patents by submitting to the FDA an Abbreviated New Drug Application (“ANDA”) seeking to market a generic version of Oxtellar XR® prior to the expiration of the Company’s patents. Filing its June 26, 2020, Complaint within 45 days of receiving Apotex’s Paragraph IV certification notice entitles Supernus to an automatic stay preventing the FDA from approving Apotex’s ANDA for 30 months from the date of the Company’s receipt of the Paragraph IV Notice Letter. On September 4, 2020, Apotex answered the Complaint and denied the substantive allegations of the Complaint, asserting affirmative defenses that include non-infringement and invalidity. Apotex also asserted Counterclaims seeking declaratory judgments of non-infringement for the nine Oxtellar XR® Orange Book patents. On October 30, 2020, the Company filed its Reply, denying the substantive allegations of Apotex’s Counterclaims. On January 27, 2022, the Court issued an Order staying all litigation proceedings and administratively terminated the action. The Court lifted the stay on July 01, 2022. Pursuant to the Court’s January 27, 2022, and July 01, 2022, Orders, the 30-month Stay was extended by 152 days from November 14, 2022, to April 15, 2023. On August 1, 2022, the Court issued an Order consolidating this lawsuit with another pending lawsuit against Apotex, C.A. No. 22-cv-322 (D.N.J.), discussed in Section II, below. The Court issued a revised Scheduling Order on December 20, 2022, that further extends the 30‑month stay. The Company entered into a settlement agreement with Apotex, and on June 27, 2023, a stipulation of dismissal without prejudice was entered by the U.S. District Court for the District of New Jersey. The agreement has been submitted to the applicable governmental agencies.
II. Supernus Pharmaceuticals, Inc. v. Apotex Inc., et al., C.A. No. 22-cv-322 (FLW)(TJB) (D.N.J.)
The Company received a Paragraph IV Notice Letter from generic drug makers Apotex Inc. and Apotex Corp. (collectively, “Apotex”) dated December 10, 2021, directed to one of its Oxtellar XR® Orange Book patents. Supernus’s U.S. Patent No. 11,166,960 generally covers once-a-day oxcarbazepine formulations and methods of treating seizures using those formulations. The FDA Orange Book lists U.S. Patent No. 11,166,960 as expiring on April 13, 2027. On January 24, 2022, the Company filed a lawsuit against Apotex alleging infringement of U.S. Patent No. 11,166,960. The Complaint—filed in the U.S. District Court for the District of New Jersey—alleges, inter alia, that Apotex infringed U.S. Patent No. 11,166,960 by submitting to the FDA an Abbreviated New Drug Application (“ANDA”) seeking to market a generic version of Oxtellar XR® prior to the expiration of U.S. Patent No. 11,166,960. On January 27, 2022, in related action, C.A. No. 20-cv-7870 (D.N.J.), the Court issued an Order staying all litigation proceedings and administratively terminated that related action. That Order further indicated that this action, i.e., C.A. No. 22-cv-322 (D.N.J.), will also be stayed. The Court lifted the stay of both actions on July 01, 2022. Pursuant to the Court’s January 27, 2022, and July 01, 2022, Orders, the 30-month Stay was extended by 152 days from November 14, 2022, to April 15, 2023. On August 1, 2022, the Court issued an Order consolidating this lawsuit with another pending lawsuit against Apotex, C.A. No. 20-cv-7870 (D.N.J.), discussed in Section I, above, and administratively terminated C.A. No. 22-cv-322 (D.N.J.). In related action C.A. No. 20-cv-7870 (D.N.J.), the Court issued a revised Scheduling Order on December 20, 2022, that further extends the 30-month stay. The Company entered into a settlement agreement with Apotex, and on June 27, 2023, a stipulation of dismissal without prejudice was entered by the U.S. District Court for the District of New Jersey. The agreement has been submitted to the applicable governmental agencies.
III. Supernus Pharmaceuticals, Inc. v. RiconPharma LLC, et al., C.A. No. 21-cv-12133 (MEF)(MAH) (D.N.J.)
The Company received a Paragraph IV Notice Letter from generic drug maker RiconPharma LLC dated April 20, 2021, directed to nine of its Oxtellar XR® Orange Book patents. Supernus’s U.S. Patent Nos. 7,722,898; 7,910,131; 8,617,600; 8,821,930; 9,119,791; 9,351,975; 9,370,525; 9,855,278; and 10,220,042 generally cover once-a-day oxcarbazepine formulations and methods of treating seizures using those formulations. The FDA Orange Book lists all nine of the Company’s Oxtellar XR® patents as expiring on April 13, 2027. On June 03, 2021, the Company filed a lawsuit against RiconPharma LLC and Ingenus Pharmaceuticals, LLC (collectively, “Ricon”) alleging infringement of the Company’s nine Oxtellar XR® patents. The Complaint—filed in the U.S. District Court for the District of New Jersey—alleges, inter alia, that Ricon infringed the Company’s Oxtellar XR® patents by submitting to the FDA an Abbreviated New Drug Application (“ANDA”) seeking to market a generic version of Oxtellar XR® prior to the expiration of the Company’s patents. Filing its June 03, 2021, Complaint within 45 days of receiving Ricon’s Paragraph IV certification notice entitles Supernus to an automatic stay preventing the FDA from approving Ricon’s ANDA for 30 months from the date of the Company’s receipt of the Paragraph IV Notice Letter. On August 30, 2021, Ricon answered the Complaint and denied the substantive allegations of the Complaint, asserting affirmative defenses that include non-infringement and invalidity. Ricon also asserted Counterclaims seeking declaratory judgments of non‑infringement for the nine Oxtellar XR® Orange Book patents. Supernus filed a motion to strike the jury demand in Ricon’s answer. On December 06, 2021, the Court signed an Order withdrawing the Jury demand from Ricon’s answer. On December 13, 2021, Ricon filed an amended Answer to Supernus’s Complaint. On December 15, 2021, the Company filed its reply, denying the substantive allegations of Ricon’s Counterclaims. On November 22, 2022, the Court issued an Order consolidating for all purposes this lawsuit with another pending lawsuit against Ricon, C.A. No. 22-cv-6340 (D.N.J.), discussed in Section IV, below. The Court issued a revised Scheduling Order on June 27, 2023, that provides a Joint Final Pretrial Order deadline of July 12, 2024. The Company entered into a settlement agreement with Ricon, and on August 21, 2023, a stipulation of dismissal without prejudice was entered by the U.S. District Court for the District of New Jersey. The agreement has been submitted to the applicable government agencies.
IV. Supernus Pharmaceuticals, Inc. v. RiconPharma LLC, et al., C.A. No. 22-cv-6340 (KM)(MAH) (D.N.J.)
The Company received a Paragraph IV Notice Letter from generic drug maker RiconPharma, LLC (“Ricon”) dated October 07, 2022, directed to one of its Oxtellar XR® Orange Book patents. Supernus’s U.S. Patent No. 11,166,960 generally covers once-a-day oxcarbazepine formulations and methods of treating seizures using those formulations. The FDA Orange Book lists U.S. Patent No. 11,166,960 as expiring on April 13, 2027. On October 28, 2022, the Company filed a lawsuit against Ricon alleging infringement of U.S. Patent No. 11,166,960. The Complaint—filed in the U.S. District Court for the District of New Jersey—alleges, inter alia, that Ricon infringed U.S. Patent No. 11,166,960 by submitting to the FDA an Abbreviated New Drug Application (“ANDA”) seeking to market a generic version of Oxtellar XR® prior to the expiration of U.S. Patent No. 11,166,960. On November 22, 2022, the Court issued an Order consolidating for all purposes this lawsuit with another pending lawsuit against Ricon, C.A. No. 21-cv-12133 (D.N.J.), discussed in Section III, above. The Court further ordered that this action—C.A. No. 22-cv-6340 (D.N.J.)—be administratively terminated.
V. Supernus Pharmaceuticals, Inc. v. Ajanta Pharma Limited, C.A. No. 22-cv-1431 (GBW) (D. Del.)
The Company received a Paragraph IV Notice Letter from generic drug maker Ajanta Pharma Limited (“Ajanta”) dated September 19, 2022, directed to ten of its Oxtellar XR® Orange Book patents. Supernus’s U.S. Patent Nos. 7,722,898; 7,910,131; 8,617,600; 8,821,930; 9,119,791; 9,351,975; 9,370,525; 9,855,278; 10,220,042; and 11,166,960 generally cover once-a-day oxcarbazepine formulations and methods of treating seizures using those formulations. The FDA Orange Book lists all ten of the Company’s Oxtellar XR® patents as expiring on April 13, 2027. On October 28, 2022, the Company filed a lawsuit against Ajanta alleging infringement of the Company’s ten Oxtellar XR® patents. The Complaint—filed in the U.S. District Court for the District of Delaware—alleges, inter alia, that Ajanta infringed the Company’s Oxtellar XR® patents by submitting to the FDA an Abbreviated New Drug Application (“ANDA”) seeking to market a generic version of Oxtellar XR® prior to the expiration of the Company’s patents. Filing its October 28, 2022, Complaint within 45 days of receiving Ajanta’s Paragraph IV certification notice entitles Supernus to an automatic stay preventing the FDA from approving Ajanta’s ANDA for 30 months from the date of the Company’s receipt of the Paragraph IV Notice Letter. On January 03, 2023, Ajanta answered the Complaint and denied the substantive allegations of the Complaint, asserting affirmative defenses that include non-infringement and invalidity. Ajanta also asserted Counterclaims seeking declaratory judgments of non-infringement and invalidity. On January 24, 2023, the Company filed its Reply, denying the substantive allegations of Ajanta’s Counterclaims. The Court issued a Scheduling Order on July 13, 2023, that sets a trial date of February 10, 2025. Pretrial discovery is ongoing as of the date of this filing.
Trokendi XR®
VI. Supernus Pharmaceuticals, Inc. v. Ajanta Pharma Limited, et al., C.A. No. 21-cv-6964 (GC)(DEA) (D.N.J.)
The Company received a Paragraph IV Notice Letter from generic drug maker Ajanta Pharma Limited dated February 10, 2021, directed to ten of its Trokendi XR® Orange Book patents. Supernus’s U.S. Patent Nos. 8,298,576; 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 generally cover once-a-day topiramate formulations and methods of treating or preventing seizures and migraines using those formulations. The FDA Orange Book currently lists United States Patent No. 8,298,576 as expiring on April 04, 2028, and United States Patent Nos. 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 as expiring on November 16, 2027. On March 26, 2021, the Company filed a lawsuit against Ajanta Pharma Limited and Ajanta Pharma USA Inc. (collectively “Ajanta”) alleging infringement of the Company’s Trokendi XR® Orange Book patents. The Complaint—filed in the U.S. District Court for the District of New Jersey—alleges, inter alia, that Ajanta infringed the Company’s Trokendi XR® patents by submitting to the FDA an Abbreviated New Drug Application (“ANDA”) seeking to market a generic version of Trokendi XR® prior to the expiration of the Company’s patents. Filing its March 26, 2021, Complaint within 45 days of receiving Ajanta’s Paragraph IV certification notice entitles Supernus to an automatic stay preventing the FDA from approving Ajanta’s ANDA for 30 months from the date of the Company’s receipt of the Paragraph IV Notice Letter. On June 07, 2021, Ajanta answered the Complaint and denied the substantive allegations of the Complaint, asserting affirmative defenses that include non-infringement and invalidity. Ajanta also asserted Counterclaims seeking declaratory judgments of non‑infringement and invalidity for the Trokendi XR® Orange Book patents. On June 28, 2021, the Company filed its reply, denying the substantive allegations of Ajanta’s Counterclaims. Following the initial Rule 16 Scheduling Conference, the Court issued a case schedule. On December 17, 2021, the Court issued an order consolidating this lawsuit with the lawsuit against Torrent, discussed in Section VII, below. The consolidation order extended the 30‑month stay preventing the FDA from approving Ajanta’s ANDA to December 16, 2023. The Company entered into a settlement agreement with Ajanta, and on April 04, 2023, a stipulation of dismissal without prejudice was entered by the U.S. District Court for the District of New Jersey. The agreement has been submitted to the applicable governmental agencies.
VII. Supernus Pharmaceuticals, Inc. v. Torrent Pharmaceuticals Ltd., et al., C.A. No. 21-cv-14268 (GC)(DEA) (D.N.J.)
The Company received a Paragraph IV Notice Letter from generic drug maker Torrent Pharmaceuticals Ltd. dated June 15, 2021, directed to ten of its Trokendi XR® Orange Book patents. Supernus’s U.S. Patent Nos. 8,298,576; 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 generally cover once-a-day topiramate formulations and methods of treating or preventing seizures and migraines using those formulations. The FDA Orange Book currently lists United States Patent No. 8,298,576 as expiring on April 04, 2028, and United States Patent Nos. 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 as expiring on November 16, 2027. On July 28, 2021, the Company filed a lawsuit against Torrent Pharmaceuticals Ltd. and Torrent Pharma Inc. (collectively, “Torrent”) alleging infringement of the Company’s Trokendi XR® Orange Book patents. The Complaint—filed in the U.S. District Court for the District of New Jersey—alleges, inter alia, that Torrent infringed the Company’s Trokendi XR® patents by submitting to the FDA an Abbreviated New Drug Application (“ANDA”) seeking to market a generic version of Trokendi XR® prior to the expiration of the Company’s patents. Filing its July 28, 2021, Complaint within 45 days of receiving Torrent’s Paragraph IV certification notice entitles Supernus to an automatic stay preventing the FDA from approving Torrent’s ANDA for 30 months from the date of the Company’s receipt of the Paragraph IV Notice Letter. On September 29, 2021, Torrent answered the Complaint and denied the substantive allegations of the Complaint, asserting affirmative defenses that include non-infringement and invalidity. Torrent also asserted Counterclaims seeking declaratory judgments of non‑infringement for the Trokendi XR® Orange Book patents. On November 3, 2021, the Company filed its reply, denying the substantive allegations of Torrent’s Counterclaims. Following the initial Rule 16 Scheduling Conference, the Court issued a case schedule. On December 17, 2021, the Court issued an order consolidating this lawsuit with the lawsuit against Ajanta, discussed in Section VI, above. The Court held a bench trial between July 31, 2023, and August 03, 2023. Closing arguments for the trial were held on October 04, 2023. The Court has not issued its trial decision as of the date of this filing.
VIII. Supernus Pharmaceuticals, Inc. v. Lupin Limited, et al., C.A. No. 21-cv-1293 (MN) (D. Del.)
The Company received a Paragraph IV Notice Letter from generic drug maker Lupin Limited dated July 29, 2021, directed to ten of its Trokendi XR® Orange Book patents. Supernus’s U.S. Patent Nos. 8,298,576; 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 generally cover once-a-day topiramate formulations and methods of treating or preventing seizures and migraines using those formulations. The FDA Orange Book currently lists United States Patent No. 8,298,576 as expiring on April 04, 2028, and United States Patent Nos. 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 as expiring on November 16,
2027. On September 10, 2021, the Company filed a lawsuit against Lupin Limited, Lupin Atlantis Holdings S.A., Nanomi B.V., Lupin Inc., and Lupin Pharmaceuticals, Inc. (collectively, “Lupin”) alleging infringement of the Company’s Trokendi XR® Orange Book patents. The Complaint—filed in the U.S. District Court for the District of Delaware—alleges, inter alia, that Lupin infringed the Company’s Trokendi XR® patents by submitting to the FDA an Abbreviated New Drug Application (“ANDA”) seeking to market a generic version of Trokendi XR® prior to the expiration of the Company’s patents. Filing its September 10, 2021, Complaint within 45 days of receiving Lupin’s Paragraph IV certification notice entitles Supernus to an automatic stay preventing the FDA from approving Lupin’s ANDA for 30 months from the date of the Company’s receipt of the Paragraph IV Notice Letter. On December 20, 2021, Lupin answered the Complaint and denied the substantive allegations of the Complaint, asserting affirmative defenses that include non-infringement and invalidity. Lupin also asserted Counterclaims seeking declaratory judgments of non‑infringement and invalidity for the Trokendi XR® Orange Book patents. On January 10, 2022, the Company filed its reply, denying the substantive allegations of Lupin’s Counterclaims. On May 11, 2023, the Company and Lupin filed a Stipulation and [Proposed] Order to Amend Scheduling Order, that proposed an extension of the 30-month stay to March 30, 2024, but also stated that “the parties do not object to the Court exercising its discretion to further extend the expiration of the 30-month stay beyond the Proposed Date of March 30, 2024 as the Court deems appropriate.” On May 12, 2023, the Court issued a revised scheduling order that provides for a Final Pretrial Conference on March 12, 2024, and a five-day bench trial beginning on March 18, 2024. Pretrial discovery is ongoing as of the date of this filing.
IX. Supernus Pharmaceuticals, Inc. v. Zydus Pharmaceuticals (USA) Inc., et al., C.A. No. 21-cv-17104 (GC)(LHG) (D.N.J.)
The Company received a Paragraph IV Notice Letter from generic drug maker Zydus Pharmaceuticals (USA) Inc. dated August 05, 2021, directed to ten of its Trokendi XR® Orange Book patents. Supernus’s U.S. Patent Nos. 8,298,576; 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 generally cover once-a-day topiramate formulations and methods of treating or preventing seizures and migraines using those formulations. The FDA Orange Book currently lists United States Patent No. 8,298,576 as expiring on April 04, 2028, and United States Patent Nos. 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 as expiring on November 16, 2027. On September 17, 2021, the Company filed a lawsuit against Zydus Pharmaceuticals (USA) Inc. and Cadila Healthcare Limited (collectively, “Zydus”) alleging infringement of the Company’s Trokendi XR® Orange Book patents. The Complaint—filed in the U.S. District Court for the District of New Jersey—alleges, inter alia, that Zydus infringed the Company’s Trokendi XR® patents by submitting to the FDA an Abbreviated New Drug Application (“ANDA”) seeking to market a generic version of Trokendi XR® prior to the expiration of the Company’s patents. Filing its September 17, 2021, Complaint within 45 days of receiving Zydus’s Paragraph IV certification notice entitles Supernus to an automatic stay preventing the FDA from approving Zydus’s ANDA for 30 months from the date of the Company’s receipt of the Paragraph IV Notice Letter. The August 05, 2021, Paragraph IV Notice Letter from Zydus Pharmaceuticals (USA) Inc. concerns Zydus’s proposed generic equivalent of the 200 mg strength of Trokendi XR®.[1] The August 05, 2021, Paragraph IV Notice Letter referenced herein does not concern the same ANDA as the one that was at issue in the previous lawsuit. On December 28, 2021, Zydus answered the Complaint and denied the substantive allegations of the Complaint, asserting affirmative defenses that include non-infringement and invalidity. On April 29, 2022, the Court issued a scheduling order. The Company entered into a settlement agreement with Zydus, and on January 06, 2023, a stipulation of dismissal without prejudice was entered by the U.S. District Court for the District of New Jersey. The agreement has been submitted to the applicable governmental agencies.
X. Supernus Pharmaceuticals, Inc. v. Alkem Laboratories Ltd., C.A. No. 22-cv-3511 (EEB)(SRH) (N.D. Ill.)
The Company received a Paragraph IV Notice Letter from generic drug maker Alkem Laboratories Ltd. dated May 25, 2022, directed to ten of its Trokendi XR® Orange Book patents. Supernus’s U.S. Patent Nos. 8,298,576; 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 generally cover once-a-day topiramate formulations and methods of treating or preventing seizures and migraines using those formulations. The FDA Orange Book currently lists United States Patent No. 8,298,576 as expiring on April 04, 2028, and United States Patent Nos. 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 as expiring on November 16, 2027. On July 6, 2022, the Company filed a lawsuit against Alkem Laboratories Ltd. (“Alkem”) alleging infringement of the Company’s Trokendi XR® Orange Book patents. The Complaint—filed in the U.S. District Court for the Northern District of Illinois—alleges, inter alia, that Alkem infringed the Company’s Trokendi XR® patents by submitting to the FDA an Abbreviated New Drug Application (“ANDA”) seeking to market a generic version of Trokendi XR® prior to the expiration of the Company’s
1 Previously, the Company was in a lawsuit against Zydus Pharmaceuticals (USA) Inc. and Cadila Healthcare Limited concerning an Abbreviated New Drug Application (“ANDA”) for Zydus’s proposed generic equivalents of the 25 mg, 50 mg, and 100 mg strengths of Trokendi XR®. A settlement agreement was entered into between the Company and Zydus Pharmaceuticals (USA) Inc. and Cadila Healthcare Limited concerning the previous lawsuit. See https://www.sec.gov/Archives/edgar/data/1356576/000110465917031191/a17-10293_1ex10d1.htm.
patents. Filing its July 06, 2022, Complaint within 45 days of receiving Alkem’s Paragraph IV certification notice entitles Supernus to an automatic stay preventing the FDA from approving Alkem’s ANDA for 30 months from the date of the Company’s receipt of the Paragraph IV Notice Letter. On October 03, 2022, Alkem answered the Complaint and denied the substantive allegations of the Complaint, asserting affirmative defenses that include non-infringement and invalidity. The Company entered into a settlement agreement with Alkem, and on March 20, 2023, a stipulation of dismissal without prejudice was entered by the U.S. District Court for the Northern District of Illinois. The agreement has been submitted to the applicable governmental agencies.
XI. Supernus Pharmaceuticals, Inc. v. Dr. Reddy’s Laboratories, Ltd., et al., C.A. No. 22-cv-4705 (GC)(JBD) (D.N.J.)
The Company received a Paragraph IV Notice Letter from generic drug makers Dr, Reddy’s Laboratories Ltd. and Dr. Reddy’s Laboratories, Inc. dated June 09, 2022, directed to ten of its Trokendi XR® Orange Book patents. Supernus’s U.S. Patent Nos. 8,298,576; 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 generally cover once-a-day topiramate formulations and methods of treating or preventing seizures and migraines using those formulations. The FDA Orange Book currently lists United States Patent No. 8,298,576 as expiring on April 04, 2028, and United States Patent Nos. 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 as expiring on November 16, 2027. On July 22, 2022, the Company filed a lawsuit against Dr, Reddy’s Laboratories Ltd. and Dr. Reddy’s Laboratories, Inc. (“DRL”) alleging infringement of the Company’s Trokendi XR® Orange Book patents. The Complaint—filed in the U.S. District Court for the District of New Jersey—alleges, inter alia, that DRL infringed the Company’s Trokendi XR® patents by submitting to the FDA an Abbreviated New Drug Application (“ANDA”) seeking to market a generic version of Trokendi XR® prior to the expiration of the Company’s patents. Filing its July 22, 2022, Complaint within 45 days of receiving DRL’s Paragraph IV certification notice entitles Supernus to an automatic stay preventing the FDA from approving DRL’s ANDA for 30 months from the date of the Company’s receipt of the Paragraph IV Notice Letter. On October 07, 2022, DRL answered the Complaint and denied the substantive allegations of the Complaint, asserting affirmative defenses that include non-infringement and invalidity. The Company entered into a settlement agreement with DRL, and on June 28, 2023, a stipulation of dismissal without prejudice was entered by the U.S. District Court for the District of New Jersey. The agreement has been submitted to the applicable governmental agencies.
XII. Supernus Pharmaceuticals, Inc. v. Ascent Pharmaceuticals Inc., et al., C.A. No. 23-cv-4015 (GC)(DEA) (D.N.J.)
The Company received a Paragraph IV Notice Letter from generic drug maker Ascent Pharmaceuticals Inc. dated June 15, 2023, directed to ten of its Trokendi XR® Orange Book patents. Supernus’s U.S. Patent Nos. 8,298,576; 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 generally cover once-a-day topiramate formulations and methods of treating or preventing seizures and migraines using those formulations. The FDA Orange Book currently lists United States Patent No. 8,298,576 as expiring on April 04, 2028, and United States Patent Nos. 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 as expiring on November 16, 2027. On July 26, 2023, the Company filed a lawsuit against Ascent Pharmaceuticals Inc., Camber Pharmaceuticals, Inc., and Hetero Labs Ltd. (collectively, “Ascent”) alleging infringement of the Company’s Trokendi XR® Orange Book patents. The Complaint—filed in the U.S. District Court for the District of New Jersey—alleges, inter alia, that Ascent infringed the Company’s Trokendi XR® patents by submitting to the FDA an Abbreviated New Drug Application (“ANDA”) seeking to market a generic version of Trokendi XR® prior to the expiration of the Company’s patents. Filing its July 26, 2023, Complaint within 45 days of receiving Ascent’s Paragraph IV certification notice entitles Supernus to an automatic stay preventing the FDA from approving Ascent’s ANDA for 30 months from the date of the Company’s receipt of the Paragraph IV Notice Letter. On September 28, 2023, the Court entered a stipulation of dismissal without prejudice as to only defendants Camber and Hetero, which included stipulations that, among other things: (i) Ascent Pharma will not contest personal jurisdiction or venue in this District for this Action; (ii) Camber and Hetero will be bound by any injunction in this Action to the extent it concerns the Ascent ANDA; and (iii) Ascent Pharma will collect and produce any relevant discovery that is in the possession, custody, or control of Camber and Hetero. On October 11, 2023, Ascent Pharma answered the Complaint and denied the substantive allegations of the Complaint, asserting affirmative defenses that include non-infringement and invalidity. The Court has not issued a Scheduling Order as of the date of this filing.
XIII. Supernus Pharmaceuticals, Inc. v. Ascent Pharmaceuticals Inc., et al., C.A. No. 23-cv-5720 (E.D.N.Y.)
The Company received a Paragraph IV Notice Letter from generic drug maker Ascent Pharmaceuticals Inc. dated June 15, 2023, directed to ten of its Trokendi XR® Orange Book patents. Supernus’s U.S. Patent Nos. 8,298,576; 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 generally cover once-a-day topiramate formulations and methods of treating or preventing seizures and migraines using those formulations. The FDA Orange Book currently lists United States Patent No. 8,298,576 as expiring on April 04, 2028, and United States Patent Nos. 8,298,580; 8,663,683; 8,877,248; 8,889,191; 8,992,989; 9,549,940; 9,555,004; 9,622,983; and 10,314,790 as expiring on November 16,
2027. On July 28, 2023, the Company filed a lawsuit against Ascent Pharmaceuticals Inc., Camber Pharmaceuticals, Inc., and Hetero Labs Ltd. (collectively, “Ascent”) alleging infringement of the Company’s Trokendi XR® Orange Book patents. The Complaint—filed in the U.S. District Court for the Eastern District of New York—alleges, inter alia, that Ascent infringed the Company’s Trokendi XR® patents by submitting to the FDA an Abbreviated New Drug Application (“ANDA”) seeking to market a generic version of Trokendi XR® prior to the expiration of the Company’s patents. Filing its July 28, 2023, Complaint within 45 days of receiving Ascent’s Paragraph IV certification notice entitles Supernus to an automatic stay preventing the FDA from approving Ascent’s ANDA for 30 months from the date of the Company’s receipt of the Paragraph IV Notice Letter. On October 25, 2023, Supernus filed a notice of voluntary dismissal of the Complaint without prejudice. The Court dismissed the case without prejudice on October 30, 2023. The October 30, 2023, dismissal does not impact the co‑pending matter against Ascent, C.A. No. 23-cv-4015 (D.N.J.), discussed in Section XII above.
APOKYN®
XIV. Sage Chemical, Inc., et al. v. Supernus Pharmaceuticals, Inc., et al., C.A. No. 22-cv-1302 (CJB) (D. Del.)
On October 03, 2022, Sage Chemical, Inc. and TruPharma, LLC filed a lawsuit in the United States District Court for the District of Delaware alleging that Supernus Pharmaceuticals, Inc., Britannia Pharmaceuticals Limited (“Britannia”), and US WorldMeds Partners, LLC (“US WorldMeds”) violated state and federal antitrust law in connection with APOKYN® (apomorphine HCl). On October 16, 2022, Plaintiffs amended their complaint to add additional defendants MDD US Enterprises, LLC, MDD US Operations, LLC (each a subsidiary of Supernus Pharmaceuticals, Inc.), USWM, LLC (“USWM”), Paul Breckinridge Jones, Sr., Herbert Lee Warren, Jr., Henry Van Den Berg, and Kristin L. Gullo. On January 10, 2023, Defendants filed an Omnibus Motion to Dismiss the Amended Complaint seeking dismissal of each of Plaintiffs’ claims and the lawsuit in its entirety and US WorldMeds with USWM, Britannia, and the group of individual defendants each filed separate motions to dismiss. As of April 12, 2023, briefing on those motions is now complete. Those motions remain pending. On April 10, 2023, the Court issued a scheduling order that provides for a Pretrial Conference on March 07, 2025, and a jury trial beginning on March 24, 2025. Pretrial discovery is ongoing as of the date of this filing.
XADAGO®
On June 10, 2021, Newron Pharmaceuticals S.p.A. ("Newron"), Zambon S.p.A. ("Zambon") and Supernus Pharmaceuticals, Inc. (the "Company"), through its subsidiary MDD US Operations, LLC (collectively, "Plaintiffs"), initiated litigation against generic drug makers Aurobindo Pharma Limited, Aurobindo Pharma USA Inc., MSN Laboratories Private Limited ("MSN"), Optimus Pharma Pvt Ltd, Prinston Pharmaceutical, Inc., RK Pharma, Inc. and Zenara Pharma Private Limited (collectively, "Defendants") for infringement of three FDA Orange Book patents covering XADAGO®, the Company's once-daily product indicated as adjunctive treatment to levodopa/carbidopa in patients with Parkinson's Disease experiencing "off" episodes. U.S. Patent Nos. 8,076,515, 8,278,485 and 8,283,380 (collectively, the "XADAGO Patents") cover the pharmaceutical formulation of and methods of treatment with safinamide. The XADAGO Patents expire between June 2027 and March 2031. The Company has a license agreement with Zambon, Newron's partner, related to the XADAGO Patents, and as a new chemical entity, XADAGO was under the 5-year FDA exclusivity period that expired on March 21, 2022. The Complaint - filed in the U.S. District Court for the District of Delaware - alleges that the Defendants infringed the XADAGO Patents by submitting to the U.S. Food and Drug Administration (FDA) Abbreviated New Drug Applications (ANDAs) seeking to market generic versions of XADAGO prior to the expiration of the patents. Filing the Complaint within 45 days of receiving each of the Defendants' Paragraph IV notice letters entitles the Plaintiffs to an automatic stay preventing the FDA from approving the Defendants' ANDAs for 30 months from the date of the Plaintiffs' receipt of the Paragraph IV Notice Letters. On March 22, 2022, defendant Optimus Pharma Pvt Ltd was dismissed from the case without prejudice. On January 05, 2023, Defendants Aurobindo Pharma Limited and Aurobindo Pharma USA Inc. were dismissed from the case without prejudice pursuant to a settlement agreement. On April 14, 2023, the Court issued a claim construction opinion and order construing terms of the asserted patent claims. On August 15, 2023, defendant Prinston Pharmaceutical, Inc. was dismissed from the case with prejudice pursuant to a settlement agreement. Fact and expert discovery are closed. A pretrial conference is set for December 08, 2023. A three-day bench trial is set to begin on January 08, 2024.
Adamas Litigation
In November 2012, Adamas Pharmaceuticals, Inc. (Adamas) granted Forest Laboratories Holdings Limited, an indirect wholly-owned subsidiary of Allergan plc (Forest), an exclusive license to certain of Adamas's intellectual property rights relating to human therapeutics containing memantine in the United States. Under the terms of that license agreement, Forest has the right to enforce such intellectual property rights which are related to its right to market and sell Namzaric and NAMENDA XR for the treatment of moderate to severe dementia related to Alzheimer's disease. Adamas has a right to participate in, but not control, such enforcement actions by Forest.
Since 2018 multiple generic companies have launched generic versions of NAMENDA XR. A number of companies have submitted ANDAs including one or more certifications to the FDA, pursuant to 21 U.S.C. § 355(j)(2)(A)(vii)(iv), requesting approval to manufacture and market generic versions of Namzaric, on which Adamas became entitled to receive royalties from Forest beginning in May 2020.
Adamas and Forest have settled with all such Namzaric ANDA filers, including all first filers on all the available dosage forms of Namzaric. Subject to those agreements, the earliest date on which any of these agreements grant a license to market a Namzaric ANDA filer's generic version of Namzaric is January 1, 2025 (or earlier in certain circumstances). Alternatively, the Namzaric ANDA filers with the earliest date have the option to launch an authorized generic version of Namzaric beginning on January 1, 2026 instead of launching their own generic version of Namzaric on January 1, 2025. Adamas and Forest intend to continue to enforce the patents associated with Namzaric.
On April 1, 2019, Adamas was served with a complaint filed in the United States District Court for the Northern District of California (Case No. 3:18-cv-03018-JCS) against it and several Forest and Allergan entities alleging violations of federal and state false claims acts (FCA) in connection with the commercialization of NAMENDA XR and Namzaric by Allergan. The lawsuit is a qui tam complaint brought by a named individual, Zachary Silbersher, asserting rights of the Federal government and various state governments. The lawsuit was originally filed in May 2018 under seal, and Adamas became aware of the lawsuit when it was served. The complaint alleges that patents held by Allergan and Adamas covering NAMENDA XR and Namzaric were procured through fraud on the United States Patent and Trademark Office and that these patents were asserted against potential generic manufacturers of NAMENDA XR and Namzaric to prevent the generic manufacturers from entering the market, thereby wrongfully excluding generic competition resulting in artificially high prices being charged to government payors.
Adamas's patents in question were licensed exclusively to Forest. The complaint includes a claim for damages of “potentially more than $2.5 billion dollars,” treble damages and statutory penalties. To date the federal and state governments have declined to intervene in this action. This case is currently stayed pending Adamas's and Allergan's interlocutory appeal of the District Court's December 11, 2020 order denying Adamas's and Allergan's motions to dismiss the complaint. The appeal was heard by the United States Court of Appeals for the Ninth Circuit (Case No. 21-80005). Argument was held on January 10, 2022. On August 25, 2022, the Ninth Circuit sided with the defendants by reversing the District Court’s public disclosure bar rulings and remanding the case back to the District Court to decide certain issues in the first instance. On October 11, 2022, the plaintiff filed a petition for rehearing with the Ninth Circuit, which was denied. On December 23, 2022, defendants filed renewed motions to dismiss directed to the remaining unresolved issue. On March 20, 2023, the district court entered an order and final judgment dismissing with prejudice the FCA claim while declining to exercise supplemental jurisdiction over the state false claims act claims which were dismissed without prejudice. On April 19, 2023, the plaintiff appealed the District Court's dismissal of the Federal False Claims Act claim.
On December 10, 2019, a putative class action lawsuit alleging violations of the federal securities laws was filed by Ali Zaidi against Adamas and certain of Adamas's former directors and officers in federal court in the Northern District of California (Case No. 4:19-cv-08051). This lawsuit alleges violations of the Securities Exchange Act of 1934 by Adamas and certain of Adamas's former directors and officers. On October 8, 2021, the presiding judge dismissed the litigation, and granted Plaintiffs leave to amend their complaint. On November 5, 2021, Plaintiffs filed their second amended class action complaint. On December 10, 2021, Adamas filed a motion to dismiss the Second Amended Complaint. Plaintiffs opposed the motion to dismiss. On January 13, 2023, the Court granted in part and denied in part Defendants’ Motion to Dismiss. All claims against Adamas have been dismissed with prejudice, but claims against one of the individual defendants, who may have certain rights to indemnification, remain. On February 27, 2023, plaintiffs advised the Court that plaintiffs would proceed only on the remaining claim against one of the individual defendants. The individual defendant filed an answer denying the claim on April 28, 2023. On September 21, 2023, the parties reached an agreement in principle to settle the Zaidi litigation, subject to court approval. On October 31, 2023, the Court granted the parties' stipulation staying all proceedings and vacating all existing deadlines. If the plaintiff has not moved for preliminary approval of a settlement by January 5, 2024, the parties are required to file a joint status report with the Court by January 8, 2024.
On March 16, 2020, a shareholder derivative lawsuit was filed by Patrick Van Camp in federal court in the Northern District of California (Case No. 4:20-cv-01815) naming Adamas and certain of Adamas's former directors and officers as defendants. This lawsuit alleged certain of Adamas's former directors and officers breached fiduciary duties and violated the Securities Exchange Act of 1934. Adamas was named as a nominal defendant only. On April 6, 2020, another, virtually identical, shareholder derivative lawsuit was filed by James Druzbik in federal court in the Northern District of California (Case No. 4:20- cv-02320) naming Adamas and certain of Adamas's former directors and officers as defendants. This lawsuit contained the same allegations, claims, and defendants as the first derivative action. Adamas is named as a nominal defendant only. In both actions, Plaintiffs sought unspecified monetary damages and other relief. These actions were consolidated. On May 16, 2023 the court entered an order dismissing the consolidated actions, without prejudice. The consolidated cases were closed on June 7, 2023.
Adamas believes it has strong factual and legal defenses to all actions and intends to defend itself vigorously.
Item 1A. Risk Factors
Any investment in our business involves a high degree of risk. Before making an investment decision, you should carefully consider the information we include in this Quarterly Report on Form 10-Q, including our condensed consolidated financial statements and related notes; the additional information in the other reports we file with the Securities and Exchange Commission; and the risks described in our Annual Report on Form 10-K for the year ended December 31, 2022 and quarterly report on Form 10-Q for the period ended September 30, 2023. These risks may result in material harm to our business and our financial condition and results of operations. If a material, adverse event was to occur, the market price of our common stock may decline, and you could lose part or all of your investment.
Item 2. Unregistered Sales of Equity Securities and Use of Proceeds
(a) Sales of Unregistered Securities.
During the nine months ended September 30, 2023, all of the Company's grants of equity awards occurred pursuant to its 2021 Equity Incentive Plan (the "2021 Plan"). Securities issued under the 2021 Plan are registered on the Company's Form S-8 filed on June 25, 2021.
Item 3. Defaults Upon Senior Securities
None.
Item 4. Mine Safety Disclosures
None.
Item 5. Other Information
(a) None.
(b) None.
(c) Insider Trading Arrangements and Policies.
During the quarter, the following trading arrangements were adopted or terminated as indicated below:
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Name and Title of Director or Officer | Rule 10b5-1 Trading Arrangement(1) | Trading Arrangement Adopted or Terminated | Date of Adoption or Termination | Duration of Trading Arrangement | Aggregate Number of Securities to be Purchased Pursuant to Trading Arrangement | Aggregate Number of Securities to be Sold Pursuant to Trading Arrangement |
Jack Khattar, President, Chief Executive Officer and Director | Yes | Adopted | August 27, 2023 | First Transaction Date(1) through March 3, 2025 | 75,037 | 75,037(2) |
Padmanabh P. Bhatt, Ph.D, Senior Vice President of Intellectual Property and Chief Scientific Officer | Yes | Adopted | September 7, 2023 | First Transaction Date(1) through April 30, 2024 | 109,250 | 109,250(2) |
___________________________________________
(1) First Transaction Date means the date that is the later of (i) the 91st day after the Date of Adoption, or (ii) the earlier of: (a) the third business day following the disclosure of the Company’s financial results in a Form 10-Q or Form 10-K for the completed fiscal quarter in which the trading arrangement was adopted, or (b) the 121st day after the Date of Adoption.
(2) This trading arrangement covers the exercise and sale of stock options, with a portion of such sales limited to an amount reasonably estimated such that the net proceeds from the sale are sufficient to cover the exercise cost and taxes associated with the exercise of the stock options.
Item 6. Exhibits
The following exhibits are filed or furnished as part of this Quarterly Report on Form 10-Q: | | | | | | | | |
Exhibit Number | | Description |
31.1 | | |
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31.2 | | |
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32.1 | | |
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32.2 | | |
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101 | | The following financial information from the Company’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2023, formatted in Inline XBRL: (i) Cover Page, (ii) Condensed Consolidated Statements of Earnings (Loss), (iii) Condensed Consolidated Statements of Comprehensive Earnings (Loss), (iv) Condensed Consolidated Balance Sheets, (v) Condensed Consolidated Statements of Changes in Stockholders' Equity, (vi) Condensed Consolidated Statements of Cash Flows, and (vii) the Notes to Condensed Consolidated Financial Statements, tagged in summary and detail. |
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104 | | The cover page of the Company’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2023, formatted in Inline XBRL (included with the Exhibit 101 attachments). |
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_______________________________________________________________________________
†† Certain portions of this exhibit that constitute confidential information have been omitted in accordance with Regulation S-K, Item 601(b)(10)(iv) because it (i) is not material and (ii) would be competitively harmful if publicly disclosed.
* Previously filed.
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized. | | | | | | | | |
| SUPERNUS PHARMACEUTICALS, INC. |
| | |
DATED: November 8, 2023 | By: | /s/ Jack A. Khattar |
| | Jack A. Khattar President and Chief Executive Officer |
| | |
DATED: November 8, 2023 | By: | /s/ Timothy C. Dec |
| | Timothy C. Dec Senior Vice-President and Chief Financial Officer |
EXHIBIT 31.1
CERTIFICATION
I, Jack A. Khattar, certify that:
1.I have reviewed this Quarterly Report on Form 10-Q of Supernus Pharmaceuticals, Inc.;
2.Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;
3.Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;
4.The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:
(a)designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;
(b)designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;
(c)evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and
(d)disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and
5.The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):
(a)all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and
(b)any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.
| | | | | | | | |
Date: November 8, 2023 | By: | /s/ Jack A. Khattar |
| | Jack A. Khattar President and Chief Executive Officer |
EXHIBIT 31.2
CERTIFICATION
I, Timothy C. Dec, certify that:
1.I have reviewed this Quarterly Report on Form 10-Q of Supernus Pharmaceuticals, Inc.;
2.Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;
3.Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;
4.The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:
(a)designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;
(b)designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;
(c)evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and
(d)disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and
5.The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):
(a)all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and
(b)any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.
| | | | | | | | |
Date: November 8, 2023 | By: | /s/ Timothy C. Dec |
| | Timothy C. Dec |
| | Senior Vice President and Chief Financial Officer |
EXHIBIT 32.1
SUPERNUS PHARMACEUTICALS, INC.
CERTIFICATION PURSUANT TO
18 U.S.C. sec. 1350,
AS ADOPTED PURSUANT TO
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002
In connection with the Quarterly Report of Supernus Pharmaceuticals, Inc. (the “Company”) on Form 10-Q for the period ended September 30, 2023 as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Jack A. Khattar, President and Chief Executive Officer of the Company, certify, pursuant to 18 U.S.C. sec. 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:
(1)The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and
(2)The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.
| | | | | | | | |
Date: November 8, 2023 | By: | /s/ Jack A. Khattar |
| | Jack A. Khattar President and Chief Executive Officer |
EXHIBIT 32.2
SUPERNUS PHARMACEUTICALS, INC.
CERTIFICATION PURSUANT TO
18 U.S.C. sec. 1350,
AS ADOPTED PURSUANT TO
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002
In connection with the Quarterly Report of Supernus Pharmaceuticals, Inc. (the “Company”) on Form 10-Q for the period ended September 30, 2023 as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Timothy C. Dec, Senior Vice President and Chief Financial Officer of the Company, certify, pursuant to 18 U.S.C. sec. 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:
(1)The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and
(2)The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.
| | | | | | | | |
Date: November 8, 2023 | By: | /s/ Timothy C. Dec |
| | Timothy C. Dec Senior Vice President and Chief Financial Officer |
v3.23.3
Cover Page - shares
|
9 Months Ended |
|
Sep. 30, 2023 |
Nov. 01, 2023 |
Cover [Abstract] |
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|
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true
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Sep. 30, 2023
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|
|
Entity File Number |
001-35518
|
|
Entity Registrant Name |
SUPERNUS PHARMACEUTICALS, INC.
|
|
Entity Incorporation, State or Country Code |
DE
|
|
Entity Tax Identification Number |
20-2590184
|
|
Entity Address, Address Line One |
9715 Key West Avenue
|
|
Entity Address, City or Town |
Rockville
|
|
Entity Address, State or Province |
MD
|
|
Entity Address, Postal Zip Code |
20850
|
|
City Area Code |
301
|
|
Local Phone Number |
838-2500
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Entity Current Reporting Status |
Yes
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Entity Interactive Data Current |
Yes
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Title of 12(b) Security |
Common Stock, $0.001 par value per share
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Entity Common Stock, Shares Outstanding |
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54,632,847
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NASDAQ
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v3.23.3
Condensed Consolidated Balance Sheets - USD ($) $ in Thousands |
Sep. 30, 2023 |
Dec. 31, 2022 |
Current assets |
|
|
Cash and cash equivalents |
$ 94,985
|
$ 93,120
|
Marketable securities |
105,204
|
368,214
|
Accounts receivable, net |
141,764
|
165,497
|
Inventories, net |
83,480
|
91,541
|
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23,927
|
15,779
|
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449,360
|
734,151
|
Long-term marketable securities |
25,125
|
93,896
|
Property and equipment, net |
13,688
|
15,173
|
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641,147
|
702,463
|
Goodwill |
117,019
|
117,019
|
Other assets |
38,821
|
39,806
|
Total assets |
1,285,160
|
1,702,508
|
Current liabilities |
|
|
Accounts payable and accrued liabilities |
78,471
|
96,342
|
Accrued product returns and rebates |
162,473
|
151,665
|
Convertible notes, net |
0
|
401,968
|
Contingent consideration, current portion |
45,880
|
21,120
|
Other current liabilities |
710
|
16,863
|
Total current liabilities |
287,534
|
687,958
|
Contingent consideration, long-term |
7,774
|
33,847
|
Operating lease liabilities, long-term |
33,841
|
35,998
|
Deferred income tax liabilities, net |
35,224
|
49,809
|
Other liabilities |
8,596
|
8,692
|
Total liabilities |
372,969
|
816,304
|
Stockholders’ equity |
|
|
Common stock, $0.001 par value; 130,000,000 shares authorized; 54,630,758 and 54,253,796 shares issued and outstanding as of September 30, 2023 and December 31, 2022, respectively |
55
|
54
|
Additional paid-in capital |
431,956
|
408,115
|
Accumulated other comprehensive loss, net of tax |
(1,206)
|
(3,210)
|
Retained earnings |
481,386
|
481,245
|
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912,191
|
886,204
|
Total liabilities and stockholders’ equity |
$ 1,285,160
|
$ 1,702,508
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v3.23.3
Condensed Consolidated Balance Sheets (Parenthetical) - $ / shares
|
Sep. 30, 2023 |
Dec. 31, 2022 |
Stockholders’ equity |
|
|
Common stock, par value (in dollars per share) |
$ 0.001
|
$ 0.001
|
Common stock shares authorized (in shares) |
130,000,000
|
130,000,000
|
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54,630,758
|
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|
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54,253,796
|
54,253,796
|
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v3.23.3
Condensed Consolidated Statements of Earnings (Loss) - USD ($) $ in Thousands |
3 Months Ended |
9 Months Ended |
Sep. 30, 2023 |
Sep. 30, 2022 |
Sep. 30, 2023 |
Sep. 30, 2022 |
Revenues |
|
|
|
|
Total revenues |
$ 153,880
|
$ 177,353
|
$ 443,207
|
$ 499,910
|
Costs and expenses |
|
|
|
|
Cost of goods sold |
19,601
|
25,878
|
64,152
|
64,267
|
Research and development |
22,655
|
19,554
|
68,246
|
56,778
|
Selling, general and administrative |
82,700
|
112,314
|
255,079
|
303,249
|
Amortization of intangible assets |
21,242
|
20,644
|
61,316
|
61,932
|
Contingent consideration expense (gain) |
(456)
|
486
|
(1,313)
|
1,894
|
Total costs and expenses |
145,742
|
178,876
|
447,480
|
488,120
|
Operating earnings (loss) |
8,138
|
(1,523)
|
(4,273)
|
11,790
|
Other income (expense) |
|
|
|
|
Interest expense |
0
|
(1,724)
|
(2,415)
|
(5,476)
|
Interest and other income, net |
1,751
|
2,803
|
8,467
|
19,289
|
Total other income (expense) |
1,751
|
1,079
|
6,052
|
13,813
|
Earnings (loss) before income taxes |
9,889
|
(444)
|
1,779
|
25,603
|
Income tax expense (benefit) |
25,865
|
(2,193)
|
1,638
|
(9,627)
|
Net earnings (loss) |
$ (15,976)
|
$ 1,749
|
$ 141
|
$ 35,230
|
Earnings (loss) per share |
|
|
|
|
Basic (in dollars per share) |
$ (0.29)
|
$ 0.03
|
$ 0.00
|
$ 0.66
|
Diluted (in dollars per share) |
$ (0.29)
|
$ 0.03
|
$ 0.00
|
$ 0.62
|
Weighted average shares outstanding |
|
|
|
|
Basic (in shares) |
54,608,963
|
53,789,674
|
54,498,687
|
53,517,838
|
Diluted (in shares) |
54,608,963
|
55,034,838
|
55,574,922
|
61,543,121
|
Net product sales |
|
|
|
|
Revenues |
|
|
|
|
Total revenues |
$ 149,004
|
$ 172,724
|
$ 417,915
|
$ 485,647
|
Royalty revenues |
|
|
|
|
Revenues |
|
|
|
|
Total revenues |
$ 4,876
|
$ 4,629
|
$ 25,292
|
$ 14,263
|
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v3.23.3
Condensed Consolidated Statements of Comprehensive Earnings (Loss) - USD ($) $ in Thousands |
3 Months Ended |
9 Months Ended |
Sep. 30, 2023 |
Sep. 30, 2022 |
Sep. 30, 2023 |
Sep. 30, 2022 |
Statement of Comprehensive Income [Abstract] |
|
|
|
|
Net earnings (loss) |
$ (15,976)
|
$ 1,749
|
$ 141
|
$ 35,230
|
Other comprehensive gain (loss) |
|
|
|
|
Unrealized gain (loss) on marketable securities, net of tax |
569
|
(1,826)
|
2,004
|
(5,585)
|
Other comprehensive gain (loss) |
569
|
(1,826)
|
2,004
|
(5,585)
|
Comprehensive earnings (loss) |
$ (15,407)
|
$ (77)
|
$ 2,145
|
$ 29,645
|
X |
- DefinitionAmount after tax of increase (decrease) in equity from transactions and other events and circumstances from net income and other comprehensive income, attributable to parent entity. Excludes changes in equity resulting from investments by owners and distributions to owners.
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v3.23.3
Condensed Consolidated Statements of Changes in Stockholder's Equity - USD ($) $ in Thousands |
Total |
Cumulative effect of adoption of ASU 2020-06 |
Balance, January 1, 2022 |
Common Stock |
Additional Paid-in Capital |
Additional Paid-in Capital
Cumulative effect of adoption of ASU 2020-06
|
Additional Paid-in Capital
Balance, January 1, 2022
|
Accumulated Other Comprehensive Earnings (Loss) |
Retained Earnings |
Retained Earnings
Cumulative effect of adoption of ASU 2020-06
|
Retained Earnings
Balance, January 1, 2022
|
Balance (in shares) at Dec. 31, 2021 |
|
|
|
53,256,094
|
|
|
|
|
|
|
|
Balance at Dec. 31, 2021 |
$ 815,851
|
$ (15,600)
|
$ 800,251
|
$ 53
|
$ 434,337
|
$ (56,212)
|
$ 378,125
|
$ 1,539
|
$ 379,922
|
$ 40,612
|
$ 420,534
|
Increase (Decrease) in Stockholders' Equity |
|
|
|
|
|
|
|
|
|
|
|
Share-based compensation |
4,025
|
|
|
|
4,025
|
|
|
|
|
|
|
Issuance of common stock under the equity award plans, net of shares withheld for employee taxes (in shares) |
|
|
|
130,211
|
|
|
|
|
|
|
|
Issuance of common stock under the equity award plans, net of shares withheld for employee taxes |
866
|
|
|
|
866
|
|
|
|
|
|
|
Net earnings (loss) |
25,616
|
|
|
|
|
|
|
|
25,616
|
|
|
Unrealized gain (loss) on marketable securities, net of tax |
(2,312)
|
|
|
|
|
|
|
(2,312)
|
|
|
|
Balance (in shares) at Mar. 31, 2022 |
|
|
|
53,386,305
|
|
|
|
|
|
|
|
Balance at Mar. 31, 2022 |
828,446
|
|
|
$ 53
|
383,016
|
|
|
(773)
|
446,150
|
|
|
Balance (in shares) at Dec. 31, 2021 |
|
|
|
53,256,094
|
|
|
|
|
|
|
|
Balance at Dec. 31, 2021 |
815,851
|
$ (15,600)
|
$ 800,251
|
$ 53
|
434,337
|
$ (56,212)
|
$ 378,125
|
1,539
|
379,922
|
$ 40,612
|
$ 420,534
|
Increase (Decrease) in Stockholders' Equity |
|
|
|
|
|
|
|
|
|
|
|
Net earnings (loss) |
35,230
|
|
|
|
|
|
|
|
|
|
|
Unrealized gain (loss) on marketable securities, net of tax |
(5,585)
|
|
|
|
|
|
|
|
|
|
|
Balance (in shares) at Sep. 30, 2022 |
|
|
|
54,053,513
|
|
|
|
|
|
|
|
Balance at Sep. 30, 2022 |
852,798
|
|
|
$ 54
|
401,026
|
|
|
(4,046)
|
455,764
|
|
|
Balance (in shares) at Mar. 31, 2022 |
|
|
|
53,386,305
|
|
|
|
|
|
|
|
Balance at Mar. 31, 2022 |
828,446
|
|
|
$ 53
|
383,016
|
|
|
(773)
|
446,150
|
|
|
Increase (Decrease) in Stockholders' Equity |
|
|
|
|
|
|
|
|
|
|
|
Share-based compensation |
4,297
|
|
|
|
4,297
|
|
|
|
|
|
|
Issuance of common stock under the equity award plans, net of shares withheld for employee taxes (in shares) |
|
|
|
106,081
|
|
|
|
|
|
|
|
Issuance of common stock under the equity award plans, net of shares withheld for employee taxes |
2,273
|
|
|
|
2,273
|
|
|
|
|
|
|
Net earnings (loss) |
7,865
|
|
|
|
|
|
|
|
7,865
|
|
|
Unrealized gain (loss) on marketable securities, net of tax |
(1,447)
|
|
|
|
|
|
|
(1,447)
|
|
|
|
Balance (in shares) at Jun. 30, 2022 |
|
|
|
53,492,386
|
|
|
|
|
|
|
|
Balance at Jun. 30, 2022 |
841,434
|
|
|
$ 53
|
389,586
|
|
|
(2,220)
|
454,015
|
|
|
Increase (Decrease) in Stockholders' Equity |
|
|
|
|
|
|
|
|
|
|
|
Share-based compensation |
4,985
|
|
|
|
4,985
|
|
|
|
|
|
|
Issuance of common stock under the equity award plans, net of shares withheld for employee taxes (in shares) |
|
|
|
561,127
|
|
|
|
|
|
|
|
Issuance of common stock under the equity award plans, net of shares withheld for employee taxes |
6,456
|
|
|
$ 1
|
6,455
|
|
|
|
|
|
|
Net earnings (loss) |
1,749
|
|
|
|
|
|
|
|
1,749
|
|
|
Unrealized gain (loss) on marketable securities, net of tax |
(1,826)
|
|
|
|
|
|
|
(1,826)
|
|
|
|
Balance (in shares) at Sep. 30, 2022 |
|
|
|
54,053,513
|
|
|
|
|
|
|
|
Balance at Sep. 30, 2022 |
$ 852,798
|
|
|
$ 54
|
401,026
|
|
|
(4,046)
|
455,764
|
|
|
Balance (in shares) at Dec. 31, 2022 |
54,253,796
|
|
|
54,253,796
|
|
|
|
|
|
|
|
Balance at Dec. 31, 2022 |
$ 886,204
|
|
|
$ 54
|
408,115
|
|
|
(3,210)
|
481,245
|
|
|
Increase (Decrease) in Stockholders' Equity |
|
|
|
|
|
|
|
|
|
|
|
Share-based compensation |
6,306
|
|
|
|
6,306
|
|
|
|
|
|
|
Issuance of common stock under the equity award plans, net of shares withheld for employee taxes (in shares) |
|
|
|
216,826
|
|
|
|
|
|
|
|
Issuance of common stock under the equity award plans, net of shares withheld for employee taxes |
1,811
|
|
|
|
1,811
|
|
|
|
|
|
|
Net earnings (loss) |
16,948
|
|
|
|
|
|
|
|
16,948
|
|
|
Unrealized gain (loss) on marketable securities, net of tax |
881
|
|
|
|
|
|
|
881
|
|
|
|
Balance (in shares) at Mar. 31, 2023 |
|
|
|
54,470,622
|
|
|
|
|
|
|
|
Balance at Mar. 31, 2023 |
$ 912,150
|
|
|
$ 54
|
416,232
|
|
|
(2,329)
|
498,193
|
|
|
Balance (in shares) at Dec. 31, 2022 |
54,253,796
|
|
|
54,253,796
|
|
|
|
|
|
|
|
Balance at Dec. 31, 2022 |
$ 886,204
|
|
|
$ 54
|
408,115
|
|
|
(3,210)
|
481,245
|
|
|
Increase (Decrease) in Stockholders' Equity |
|
|
|
|
|
|
|
|
|
|
|
Net earnings (loss) |
141
|
|
|
|
|
|
|
|
|
|
|
Unrealized gain (loss) on marketable securities, net of tax |
$ 2,004
|
|
|
|
|
|
|
|
|
|
|
Balance (in shares) at Sep. 30, 2023 |
54,253,796
|
|
|
54,630,758
|
|
|
|
|
|
|
|
Balance at Sep. 30, 2023 |
$ 912,191
|
|
|
$ 55
|
431,956
|
|
|
(1,206)
|
481,386
|
|
|
Balance (in shares) at Mar. 31, 2023 |
|
|
|
54,470,622
|
|
|
|
|
|
|
|
Balance at Mar. 31, 2023 |
912,150
|
|
|
$ 54
|
416,232
|
|
|
(2,329)
|
498,193
|
|
|
Increase (Decrease) in Stockholders' Equity |
|
|
|
|
|
|
|
|
|
|
|
Share-based compensation |
6,088
|
|
|
|
6,088
|
|
|
|
|
|
|
Issuance of common stock under the equity award plans, net of shares withheld for employee taxes (in shares) |
|
|
|
122,279
|
|
|
|
|
|
|
|
Issuance of common stock under the equity award plans, net of shares withheld for employee taxes |
1,947
|
|
|
$ 1
|
1,946
|
|
|
|
|
|
|
Net earnings (loss) |
(831)
|
|
|
|
|
|
|
|
(831)
|
|
|
Unrealized gain (loss) on marketable securities, net of tax |
554
|
|
|
|
|
|
|
554
|
|
|
|
Balance (in shares) at Jun. 30, 2023 |
|
|
|
54,592,901
|
|
|
|
|
|
|
|
Balance at Jun. 30, 2023 |
919,908
|
|
|
$ 55
|
424,266
|
|
|
(1,775)
|
497,362
|
|
|
Increase (Decrease) in Stockholders' Equity |
|
|
|
|
|
|
|
|
|
|
|
Share-based compensation |
7,920
|
|
|
|
7,920
|
|
|
|
|
|
|
Issuance of common stock under the equity award plans, net of shares withheld for employee taxes (in shares) |
|
|
|
37,857
|
|
|
|
|
|
|
|
Issuance of common stock under the equity award plans, net of shares withheld for employee taxes |
(230)
|
|
|
|
(230)
|
|
|
|
|
|
|
Net earnings (loss) |
(15,976)
|
|
|
|
|
|
|
|
(15,976)
|
|
|
Unrealized gain (loss) on marketable securities, net of tax |
$ 569
|
|
|
|
|
|
|
569
|
|
|
|
Balance (in shares) at Sep. 30, 2023 |
54,253,796
|
|
|
54,630,758
|
|
|
|
|
|
|
|
Balance at Sep. 30, 2023 |
$ 912,191
|
|
|
$ 55
|
$ 431,956
|
|
|
$ (1,206)
|
$ 481,386
|
|
|
X |
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v3.23.3
Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands |
9 Months Ended |
Sep. 30, 2023 |
Sep. 30, 2022 |
Cash flows from operating activities |
|
|
Net earnings (loss) |
$ 141
|
$ 35,230
|
Adjustments to reconcile net earnings (loss) to net cash provided by operating activities: |
|
|
Depreciation and amortization |
63,183
|
64,694
|
Other income from Navitor (see Note 4) |
0
|
(12,888)
|
Amortization of deferred financing costs and debt discount |
532
|
1,582
|
Realized gains from sales of marketable securities |
0
|
(14)
|
Amortization of premium/discount on marketable securities |
(849)
|
3,215
|
Change in fair value of contingent consideration |
(1,313)
|
1,894
|
Other noncash adjustments, net |
10,485
|
7,983
|
Share-based compensation expense |
20,314
|
13,307
|
Deferred income tax benefit |
(15,255)
|
(18,564)
|
Changes in operating assets and liabilities: |
|
|
Accounts receivable |
21,155
|
(14,958)
|
Inventories |
1,082
|
(6,304)
|
Prepaid expenses and other assets |
(8,138)
|
3,098
|
Accrued product returns and rebates |
10,808
|
25,746
|
Accounts payable and other liabilities |
(36,018)
|
(12,659)
|
Contingent consideration |
0
|
(2,100)
|
Net cash provided by operating activities |
66,127
|
89,262
|
Cash flows from investing activities |
|
|
Purchases of marketable securities |
0
|
(340,665)
|
Sales and maturities of marketable securities |
335,297
|
173,189
|
Purchases of property and equipment |
(587)
|
(422)
|
Net cash provided by (used in) investing activities |
334,710
|
(167,898)
|
Cash flows from financing activities |
|
|
Proceeds from Line of Credit |
93,000
|
0
|
Payments on Line of Credit |
(93,000)
|
0
|
Payment on convertible notes |
(402,500)
|
0
|
Payment of contingent consideration |
0
|
(22,900)
|
Proceeds from issuance of common stock |
3,528
|
9,594
|
Net cash used in financing activities |
(398,972)
|
(13,306)
|
Net change in cash and cash equivalents |
1,865
|
(91,942)
|
Cash and cash equivalents at beginning of year |
93,120
|
203,434
|
Cash and cash equivalents at end of period |
94,985
|
111,492
|
Supplemental cash flow information |
|
|
Cash paid for interest on debt |
1,946
|
2,516
|
Cash paid for income taxes |
27,055
|
14,558
|
Cash paid for operating leases |
13,242
|
9,547
|
Noncash investing and financing activities |
|
|
Lease assets obtained for new operating leases |
5,903
|
973
|
Deferred legal fees and fixed assets included in accounts payable and accrued expenses |
0
|
144
|
Property and equipment additions from utilization of tenant improvement allowance |
$ 0
|
$ 580
|
X |
- DefinitionDeferred Legal Fees and Fixed Assets Included in Accounts Payable and Accrued Expenses
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v3.23.3
Business Organization
|
9 Months Ended |
Sep. 30, 2023 |
Organization, Consolidation and Presentation of Financial Statements [Abstract] |
|
Business Organization |
Business Organization Supernus Pharmaceuticals, Inc. (the "Company", see Note 2, Consolidation) is a biopharmaceutical company focused on developing and commercializing products for the treatment of central nervous system (CNS) diseases. The Company's diverse neuroscience portfolio includes approved treatments for epilepsy, migraine, attention-deficit hyperactivity disorder (ADHD), hypomobility in Parkinson’s Disease (PD), cervical dystonia, chronic sialorrhea, dyskinesia in PD patients receiving levodopa-based therapy, and drug-induced extrapyramidal reactions in adult patients. The Company is developing a broad range of novel CNS product candidates including new potential treatments for hypomobility in PD, epilepsy, depression, and other CNS disorders. The Company has eight commercial products that it markets: Qelbree®, GOCOVRI®, Trokendi XR®, Oxtellar XR®, APOKYN®, XADAGO®, Osmolex ER®, and MYOBLOC®. In addition, SPN-830 (apomorphine infusion device) is a late-stage drug/device combination product candidate for the continuous treatment of motor fluctuations ("off" episodes) in PD patients that are not adequately controlled with oral levodopa and one or more adjunct PD medications.
|
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- DefinitionThe entire disclosure for the nature of an entity's business, major products or services, principal markets including location, and the relative importance of its operations in each business and the basis for the determination, including but not limited to, assets, revenues, or earnings. For an entity that has not commenced principal operations, disclosures about the risks and uncertainties related to the activities in which the entity is currently engaged and an understanding of what those activities are being directed toward.
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v3.23.3
Summary of Significant Accounting Policies
|
9 Months Ended |
Sep. 30, 2023 |
Accounting Policies [Abstract] |
|
Summary of Significant Accounting Policies |
Summary of Significant Accounting Policies Basis of Presentation The Company’s unaudited condensed consolidated financial statements have been prepared in accordance with the requirements of the U.S. Securities and Exchange Commission (SEC) for interim financial information. As permitted under Generally Accepted Accounting Principles in the United States (U.S. GAAP), certain notes and other information have been omitted from the interim unaudited condensed consolidated financial statements presented in this Quarterly Report on Form 10-Q. Therefore, these unaudited condensed consolidated financial statements should be read in conjunction with the Company’s most recent Annual Report on Form 10-K, for the year ended December 31, 2022, filed with the SEC. In management’s opinion, the unaudited condensed consolidated financial statements include all normal and recurring adjustments necessary for a fair presentation of the Company’s financial position, results of operations, and cash flows. The results of operations for any interim period are not necessarily indicative of the Company’s future quarterly or annual results. The Company, which is primarily located in the U.S., operates in one operating segment. Consolidation The Company's unaudited condensed consolidated financial statements include the accounts of Supernus Pharmaceuticals, Inc. and its wholly owned subsidiaries. These are collectively referred to herein as "Supernus" or "the Company." Supernus Pharmaceuticals, Inc. and each of its subsidiaries are distinct legal entities. All significant intercompany transactions and balances have been eliminated in consolidation. The unaudited condensed consolidated financial statements reflect the consolidation of entities in which the Company has a controlling financial interest. In determining whether there is a controlling financial interest, the Company considers if it has a majority of the voting interests of the entity, or if the entity is a variable interest entity (VIE) and if the Company is the primary beneficiary. In determining the primary beneficiary of a VIE, the Company evaluates whether it has both: the power to direct the activities of the VIE that most significantly impact the VIE's economic performance; and the obligation to absorb losses of, or the right to receive benefits from the VIE that could potentially be significant to that VIE. The Company's judgment with respect to its level of influence or control of an entity involves the consideration of various factors, including the form of an ownership interest; representation in the entity's governance; the size of the investment; estimates of future cash flows; the ability to participate in policymaking decisions; and the rights of the other investors to participate in the decision making process, including the right to liquidate the entity, if applicable. If the Company is not the primary beneficiary of the VIE, and an ownership interest is maintained in the entity, the interest is accounted for under the equity or cost methods of accounting, as appropriate. The Company continuously assesses whether it is the primary beneficiary of a VIE as changes to existing relationships or future transactions may affect its conclusions. Use of Estimates The Company bases its estimates on: historical experience; forecasts; information received from its service providers; information from other sources, including public and proprietary sources; and other assumptions that the Company believes are reasonable under the circumstances. Actual results could differ materially from the Company’s estimates. The Company periodically evaluates the methodologies employed in making its estimates. Advertising Expense Advertising expense includes the cost of promotional materials and activities, such as printed materials and digital marketing, marketing programs and speaker programs. The costs of the Company's advertising efforts are expensed as incurred. The Company incurred approximately $25.1 million and $76.9 million in advertising expense for the three and nine months ended September 30, 2023, respectively, and approximately $52.0 million and $112.8 million for the three and nine months ended September 30, 2022. These expenses are recorded as a component of Selling, general and administrative expenses in the unaudited condensed consolidated statements of earnings (loss). Restricted Cash On March 30, 2023, the Company transferred funds totaling $403.8 million, which was reported as restricted cash in the first quarter of 2023, to the Trustee (Wilmington Trust) related to the repayment of the 2023 Notes. On April 1, 2023, the Company paid the total principal amount due of $402.5 million under the 2023 Notes and the remaining outstanding interest due of $1.3 million with the restricted cash. Refer to Note 8, Debt. Line of Credit Line of credit includes borrowings under the uncommitted demand secured line of credit. On February 8, 2023, the Company entered into a credit line agreement (the “Credit Line”) with UBS Bank USA (“UBS”). The Credit Line provides for a revolving line of credit of up to $150 million, which can be drawn at any time. Refer to Note 8, Debt. Recently Issued Accounting Pronouncements Accounting Pronouncements Adopted Accounting Standards Update (ASU) 2020-06, Debt - Debt with Conversion and Other Options (Subtopic 470-20) and Derivatives and Hedging - Contracts in Entity's Own Equity (Subtopic 815-40): Accounting for Convertible Instruments and Contracts in an Entity's Own Equity - The new standard, issued in August 2020, simplifies the accounting for certain financial instruments with characteristics of liabilities and equity, including convertible debt instruments with cash conversion and beneficial conversion features. ASU 2020-06 eliminates requirements to separately account for liability and equity components of such convertible debt instruments and eliminates the ability to use the treasury stock method for calculating diluted earnings per share for convertible instruments whose principal amount may be settled in whole or in part with equity. Instead, ASU 2020-06 requires (i) the entire amount of the security to be presented as a liability on the balance sheet and (ii) application of the “if-converted” method for calculating diluted earnings per share. This new standard also removes certain settlement conditions required for equity contracts to qualify for the derivative scope exception. The Company adopted the new guidance as of January 1, 2022 using the modified retrospective method of transition which allows for a cumulative-effect adjustment to the opening balance of retained earnings in the period of adoption. As a result, the cumulative effect of the accounting change increased the carrying amount of the convertible notes, net by $20.6 million, increased retained earnings by $40.6 million, reduced additional paid-in capital by $56.2 million, and decreased deferred tax liabilities by $5.0 million as of January 1, 2022. Upon adoption, the Company began calculating diluted earnings per share under the if-converted method.
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- DefinitionThe entire disclosure for all significant accounting policies of the reporting entity.
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v3.23.3
Disaggregated Revenues
|
9 Months Ended |
Sep. 30, 2023 |
Disaggregation of Revenue [Abstract] |
|
Disaggregated Revenues |
Disaggregated Revenues The following table summarizes the disaggregation of revenues by product or source, (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Nine Months Ended September 30, | | 2023 | | 2022 | | 2023 | | 2022 | | (unaudited) | | (unaudited) | Net product sales | | | | | | | | Qelbree | $ | 37,081 | | | $ | 18,326 | | | $ | 93,840 | | | $ | 37,708 | | GOCOVRI | 32,889 | | | 27,878 | | | 87,650 | | | 75,179 | | Oxtellar XR | 29,644 | | | 30,528 | | | 82,359 | | | 88,007 | | Trokendi XR | 20,625 | | | 69,599 | | | 74,734 | | | 204,033 | | APOKYN | 21,510 | | | 18,261 | | | 56,324 | | | 57,156 | | Other(1) | 7,255 | | | 8,132 | | | 23,008 | | | 23,564 | | Total net product sales | $ | 149,004 | | | $ | 172,724 | | | $ | 417,915 | | | $ | 485,647 | | Royalty revenues | 4,876 | | | 4,629 | | | 25,292 | | | 14,263 | | Total revenues | $ | 153,880 | | | $ | 177,353 | | | $ | 443,207 | | | $ | 499,910 | |
___________________________________________ (1) Includes net product sales of MYOBLOC, XADAGO and Osmolex ER. The decrease in Trokendi XR net product sales for the three and nine months ended September 30, 2023, compared to the same period in 2022 was primarily attributable to the loss of exclusivity with generic entrants in January 2023. The following table shows the percentage of net product sales to total net product sales: | | | | | | | | | | | | | | | | | | | | | | | | | Percentage of Net Product Sales | | Three Months Ended September 30, | | Nine Months Ended September 30, | | 2023 | | 2022 | | 2023 | | 2022 | Qelbree | 25% | | 11% | | 22% | | 8% | GOCOVRI | 22% | | 16% | | 21% | | 15% | Oxtellar XR | 20% | | 18% | | 20% | | 18% | Trokendi XR | 14% | | 40% | | 18% | | 42% | APOKYN | 14% | | 10% | | 13% | | 12% | Other(1) | 5% | | 5% | | 6% | | 5% | Total | 100% | | 100% | | 100% | | 100% | ___________________________________________(1) Includes net product sales of MYOBLOC, XADAGO and Osmolex ER. Each of our three major customers, AmerisourceBergen Drug Corporation, Cardinal Health, Inc. and McKesson Corporation, individually accounted for more than 20% of our total net product sales and collectively accounted for more than 70% of our total net product sales for the three and nine months ended September 30, 2023 and 2022. The Company recognized noncash royalty revenue of $4.0 million for the nine months ended September 30, 2023. The Company recognized noncash royalty revenue of $2.5 million and $7.2 million for the three and nine months ended September 30, 2022, respectively. Refer to Note 15, Commitments and Contingencies.
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v3.23.3
Investments
|
9 Months Ended |
Sep. 30, 2023 |
Investments, Debt and Equity Securities [Abstract] |
|
Investments |
Investments Marketable Securities Unrestricted available-for-sale marketable securities held by the Company are as follows, (dollars in thousands): | | | | | | | | | | | | | September 30, 2023 | | December 31, 2022 | | (unaudited) | | | Corporate and municipal debt securities | | | | Amortized cost | $ | 131,891 | | | $ | 466,333 | | Gross unrealized gains | 1 | | | 14 | | Gross unrealized losses | (1,563) | | | (4,237) | | Total fair value | $ | 130,329 | | | $ | 462,110 | |
The contractual maturities of the unrestricted available-for-sale marketable securities held by the Company are as follows, (dollars in thousands): | | | | | | | September 30, 2023 | | (unaudited) | Less than 1 year | $ | 105,204 | | 1 year to 2 years | 25,125 | | | | | | | | Total | $ | 130,329 | |
As of September 30, 2023, there was no impairment due to credit loss on any available-for-sale marketable securities. Investment in Navitor Development Agreement In April 2020, the Company entered into a development agreement (the Development Agreement) with Navitor Pharmaceuticals, Inc. (Navitor Inc.). The Company can terminate the Development Agreement upon 30 days' notice. Under the terms of the Development Agreement, the Company and Navitor Inc. will jointly conduct a Phase II clinical program for NV-5138 (SPN-820) for treatment-resistant depression. The Company will bear all of the Phase I and Phase II development costs incurred by either party, up to a maximum of $50 million. In addition, the Company will incur certain other research and development support costs. There are certain additional payment amounts which could be incurred by the Company. These costs are contingent upon Navitor Inc. achieving defined development milestones. The Company has an option to acquire or license NV-5138 (SPN-820), for which additional payments would be required. Equity investment In addition to entering into the Development Agreement in April 2020, the Company acquired Series D Preferred Shares of Navitor Inc. for $15 million, representing an approximately 13% ownership position in Navitor Inc. In March 2021, Navitor Inc. underwent a legal restructuring. In the restructuring, Navitor Inc. became a wholly owned subsidiary of a newly formed limited liability company, Navitor Pharmaceuticals LLC (Navitor LLC), and the outstanding shares of stock in Navitor Inc. were exchanged for units of membership in Navitor LLC having equivalent rights and preferences (Navitor Restructuring). As part of the Navitor Restructuring, the Series D Preferred Shares previously held by the Company were exchanged for Series D Preferred Shares in Navitor LLC. In addition, certain assets that did not relate to NV-5138 (SPN-820) were transferred from Navitor Inc. to a newly formed entity that became a separate, wholly owned subsidiary of Navitor LLC. The Company had determined that Navitor LLC is a VIE. The Company does not consolidate this VIE because the Company lacks the power to direct the activities that most significantly impact Navitor’s economic performance. Prior to the Navitor Restructuring, the investment was accounted for under the practical expedient allowed for equity securities without readily determinable fair value, which is cost minus impairment plus any changes in observable price changes from an orderly transaction of similar investments in Navitor Inc. Following the legal restructuring and exchange of the preferred shares for member equity units of Navitor LLC, the investment was accounted for under the equity method of accounting due to the Company's ability to exert significant influence over but not control the financial and operating decisions of Navitor LLC. As a result of the change from a cost method investment to an equity method investment, the Company was required to measure its investment initially in accordance with the guidance in ASC 805. The majority of the assets and liabilities recorded in Navitor LLC's financial statements represent working capital items and cash that are being used for research and development purposes and are significantly lower than the Company's investment in Navitor LLC, which created a significant basis difference for the Company's investment in the underlying net assets. The Company determined that substantially all of the fair value of the investment was attributable to a single in-process research and development (IPR&D) asset. As a result, Navitor LLC was not considered a business as defined in ASC 805. In the first quarter of 2021, the $15 million investment, which was previously recorded in Other assets in the unaudited condensed consolidated balance sheets, was expensed and recorded in Research and development expense. The Company records its share of the results of Navitor LLC, a private company, on a quarter lag as the financial information of Navitor LLC is not available on a sufficiently timely basis for the Company to apply the equity method of accounting. In December 2021, Navitor LLC sold one of its subsidiaries and distributed cash to its members in accordance with each member's share of the proceeds from the sale. The Company received $12.9 million in December 2021 from Navitor LLC in connection with this sale. As the Company's policy is to record its share of the results in its equity method investment on a quarter lag as previously indicated, the Company recorded the cash amount received in Other current liabilities in the consolidated balance sheets as of December 31, 2021. In the first quarter of 2022, the Company determined its estimated share of Navitor LLC's year-end 2021 earnings and recorded a gain of $12.9 million in Interest and other income, net in the unaudited condensed consolidated statement of earnings (loss). The maximum exposure to losses related to Navitor LLC is a maximum of approximately $50 million in expense for Phase I and Phase II development of NV-5138 (SPN-820), and the cost of other development and formulation activities provided by the Company. Subsequent to the Development Agreement entered into in 2020, no additional equity investment has been made or financing has been provided to Navitor LLC.
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- DefinitionThe entire disclosure for investments in certain debt and equity securities.
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v3.23.3
Fair Value of Financial Measurements
|
9 Months Ended |
Sep. 30, 2023 |
Fair Value Disclosures [Abstract] |
|
Fair Value of Financial Measurements |
Fair Value of Financial Measurements The fair value of an asset or liability represents the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between unrelated market participants. The Company reports the fair value of assets and liabilities using a three level measurement hierarchy that prioritizes the inputs used to measure fair value. Fair value hierarchy consists of the following three levels: •Level 1—Valuations based on unadjusted quoted prices in active markets that are accessible at measurement date for identical assets. •Level 2—Valuations based on quoted prices for similar assets or liabilities in active markets, quoted prices for identical or similar assets or liabilities in markets that are not active and model-based valuations in which all significant inputs are observable in the market, either directly or indirectly (e.g., interest rates; yield curves). •Level 3—Valuations using significant inputs that are unobservable in the market and inputs that reflect the Company’s own assumptions. These are based on the best information available, including the Company’s own data. The fair value of the restricted marketable securities is recorded in Other assets on the unaudited condensed consolidated balance sheets. There have been no transfers of assets or liabilities into or out of Level 3 of the fair value hierarchy. Financial Assets and Liabilities Recorded at Fair Value The Company’s financial assets that are required to be measured at fair value on a recurring basis are as follows (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | | | Fair Value Measurements as of September 30, 2023 (unaudited) | | Total Fair Value as of September 30, 2023 (unaudited) | | Level 1 | | Level 2 | | Level 3 | Assets: | | | | | | | | Cash and cash equivalents | | | | | | | | Cash | $ | 38,302 | | | $ | 38,302 | | | $ | — | | | $ | — | | Money market securities and funds | 56,683 | | | 56,683 | | | — | | | — | | Marketable securities | | | | | | | | Corporate and municipal debt securities | 105,204 | | | — | | | 105,204 | | | — | | | | | | | | | | Long-term marketable securities | | | | | | | | Corporate and municipal debt securities | 25,125 | | | — | | | 25,125 | | | — | | | | | | | | | | Other assets | | | | | | | | Marketable securities - restricted (SERP) | 512 | | | 14 | | | 498 | | | — | | Total assets at fair value | $ | 225,826 | | | $ | 94,999 | | | $ | 130,827 | | | $ | — | | Liabilities: | | | | | | | | Contingent consideration | $ | 53,654 | | | $ | — | | | $ | — | | | $ | 53,654 | | Total liabilities at fair value | $ | 53,654 | | | $ | — | | | $ | — | | | $ | 53,654 | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | Fair Value Measurements as of December 31, 2022 | | Total Fair Value as of December 31, 2022 | | Level 1 | | Level 2 | | Level 3 | Assets: | | | | | | | | Cash and cash equivalents | | | | | | | | Cash | $ | 52,181 | | | $ | 52,181 | | | $ | — | | | $ | — | | Money market securities and funds | 40,939 | | | 40,939 | | | — | | | — | | Marketable securities | | | | | | | | Corporate and municipal debt securities | 368,214 | | | — | | | 368,214 | | | — | | | | | | | | | | Long-term marketable securities | | | | | | | | Corporate and municipal debt securities | 93,896 | | | — | | | 93,896 | | | — | | | | | | | | | | Other assets | | | | | | | | Marketable securities - restricted (SERP) | 496 | | | 11 | | | 485 | | | — | | Total assets at fair value | $ | 555,726 | | | $ | 93,131 | | | $ | 462,595 | | | $ | — | | Liabilities: | | | | | | | | Contingent consideration | $ | 54,967 | | | $ | — | | | $ | — | | | $ | 54,967 | | Total liabilities at fair value | $ | 54,967 | | | $ | — | | | $ | — | | | $ | 54,967 | |
Other Financial Instruments The carrying amounts of other financial instruments, including accounts receivable, accounts payable, and accrued expenses approximate fair value due to their short-term maturities. Financial Liabilities Recorded at Carrying Value On April 1, 2023, the Company paid the total principal amount due of $402.5 million under the 2023 Notes and the outstanding interest due of $1.3 million. As of December 31, 2022, the carrying value and fair value of the 2023 Notes which were not carried at fair value was as follows (dollars in thousands): | | | | | | | | | | | | | December 31, 2022 | | Carrying Value | | Fair Value (Level 2) | | | | | Convertible notes, net | $ | 401,968 | | | $ | 395,959 | |
The fair value has been estimated based on actual trading information, and quoted prices, both provided by bond traders.
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v3.23.3
Contingent Consideration
|
9 Months Ended |
Sep. 30, 2023 |
Business Combination and Asset Acquisition [Abstract] |
|
Contingent Consideration |
Contingent Consideration The following table provides the current and long-term portions related to the contingent consideration for the USWM Acquisition and Adamas Acquisition (dollars in thousands): | | | | | | | | | | | | | September 30, 2023 | | December 31, 2022 | Reported under the following captions in the condensed consolidated balance sheets: | (unaudited) | | | Contingent consideration, current portion | $ | 45,880 | | | $ | 21,120 | | Contingent consideration, long-term | 7,774 | | | 33,847 | | Total | $ | 53,654 | | | $ | 54,967 | |
The Company's contingent consideration liabilities are related to the USWM Acquisition in 2020 and the Adamas Acquisition in 2021 (each acquisition as defined below). The contingent consideration liabilities are measured at fair value using either a Monte Carlo simulation or the income approach. The Company classifies its contingent consideration liabilities as Level 3 fair value measurements based on the significant unobservable inputs used to estimate fair value. These reflect the inputs and assumptions the Company believes would be made by market participants. Changes in any of those inputs together or in isolation may result in significantly lower or higher fair value measurement. The change in fair value is reported on the condensed consolidated statement of earnings (loss) in Contingent consideration (gain) expense. USWM Contingent Consideration On June 9, 2020 (the USWM Closing Date), the Company completed its acquisition of all the outstanding equity of USWM Enterprises, LLC (USWM Enterprises) (USWM Acquisition). The USWM Acquisition included potential additional contingent consideration payments for regulatory and development milestones and sales-based milestones. As of September 30, 2023, the potential contingent consideration payments are up to $85 million, which is comprised of the potential $55 million in regulatory and development milestones and $30 million in sales-based milestones. •Regulatory and development milestones: The potential $55 million in regulatory and development milestones is comprised of (1) $25 million related to the FDA's approval of the SPN-830 NDA and (2) $30 million related to the subsequent commercial product launch. •Sales-based milestones: The potential $30 million sales-based milestone relates to the achievement of certain net product sales of the acquired USWM products in 2023. As of September 30, 2023, the Company assessed that this remaining $30 million sales-based milestone will not be achieved based on net sales projections. The key assumptions considered in estimating the fair value include the estimated probability and timing of milestone achievement, such as the probability and timing of obtaining regulatory approval, discount rate, and the estimated amount and timing of projected revenues from the acquired USWM products. Adamas Contingent Consideration On November 24, 2021 (the Adamas Closing Date), the Company completed its acquisition of all the outstanding equity of Adamas (Adamas Acquisition). The Adamas Acquisition included payment of two non-tradable contingent value rights (CVRs) each of which represents the contractual right to receive a contingent payment upon the achievement of the applicable aggregate worldwide net product sales of GOCOVRI. Each CVR represents the contractual right to receive a contingent payment of $0.50 per share in cash, less any applicable withholding taxes and without interest, upon the achievement of the applicable milestone (each such amount, a Milestone Payment) in accordance with the terms of a Contingent Value Rights Agreement entered into between the Company and American Stock Transfer & Trust Company, LLC, as rights agent, as further defined in the CVR agreement. One Milestone Payment is payable (subject to certain terms and conditions) upon the first occurrence of the achievement of aggregate worldwide net sales of GOCOVRI in excess of $150 million during any consecutive 12-month period ending on or before December 31, 2024 (Milestone 2024). Another Milestone Payment is payable (subject to certain terms and conditions) upon the first occurrence of the achievement of aggregate worldwide net sales of GOCOVRI in excess of $225 million during any consecutive 12-month period ending on or before December 31, 2025 (Milestone 2025 and, together with Milestone 2024, the Milestones). Each Milestone may only be achieved once. The possible outcomes for the contingent consideration range from $0 to $50.9 million on an undiscounted basis. The key assumptions considered in estimating the fair value of the Adamas sales-based milestones include the estimated revenue projections, volatility, estimated discount rates and risk-free interest rate. Change in the Fair Value of Contingent Consideration The following tables provide a reconciliation of the beginning and ending balances related to the contingent consideration for the USWM Acquisition and Adamas Acquisition (dollars in thousands): | | | | | | | | | | | | | | | | | | | USWM Acquisition | | Adamas Acquisition | | Total | Balance at December 31, 2022 | $ | 46,270 | | | $ | 8,697 | | | $ | 54,967 | | Change in fair value recognized in earnings | (1,710) | | | 63 | | | (1,647) | | Balance at March 31, 2023 (unaudited) | 44,560 | | | 8,760 | | | 53,320 | | Change in fair value recognized in earnings | 660 | | | 130 | | | 790 | | Balance at June 30, 2023 (unaudited) | 45,220 | | | 8,890 | | | 54,110 | | Change in fair value recognized in earnings | 660 | | | (1,116) | | | (456) | | Balance at September 30, 2023 (unaudited) | $ | 45,880 | | | $ | 7,774 | | | $ | 53,654 | |
| | | | | | | | | | | | | | | | | | | USWM Acquisition | | Adamas Acquisition | | Total | Balance at December 31, 2021 | $ | 70,170 | | | $ | 10,307 | | | $ | 80,477 | | Milestone payments | (25,000) | | | — | | | (25,000) | | Change in fair value recognized in earnings | 1,720 | | | (1,055) | | | 665 | | Balance at March 31, 2022 (unaudited) | 46,890 | | | 9,252 | | | 56,142 | | Change in fair value recognized in earnings | 350 | | | 393 | | | 743 | | Balance at June 30, 2022 (unaudited) | 47,240 | | | 9,645 | | | 56,885 | | Change in fair value recognized in earnings | 350 | | | 136 | | | 486 | | Balance at September 30, 2022 (unaudited) | $ | 47,590 | | | $ | 9,781 | | | $ | 57,371 | |
The Company recorded a $0.7 million expense and a $0.4 million gain due to the change in the fair value of the contingent consideration liabilities for the USWM milestones for the three and nine months ended September 30, 2023 primarily driven by the passage of time in both periods, as well as the change in timing of milestone achievement and estimated discount rate in the first quarter of 2023. The Company recorded a $0.4 million expense and a $2.4 million expense due to the change in the fair value of the contingent consideration liabilities for the USWM milestones for the three and nine months ended September 30, 2022 primarily driven by the passage of time and the accretion to the payout amount related to the milestone achieved in the first quarter of 2022. The Company recorded a $1.1 million gain and a $0.9 million gain due to the change in fair value of the contingent consideration liabilities for the Adamas CVRs for the three and nine months ended September 30, 2023 primarily driven by the passage of time. The Company recorded a $0.1 million expense and a $0.5 million gain due to the change in fair value of the contingent consideration liabilities for the Adamas CVRs for the three and nine months ended September 30, 2022 primarily driven by the passage of time. The Company paid $25 million in the first quarter of 2022 of which $22.9 million represents the acquisition date fair value of the contingent consideration liability and was reported under cash flows from financing activities. The remaining $2.1 million represents the excess of the acquisition date fair value and was reported under cash flows from operating activities. The amount paid was for the milestone that was due upon the FDA acceptance of the SPN-830 NDA for review, which was achieved in the first quarter of 2022.
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v3.23.3
Intangible Assets, Net
|
9 Months Ended |
Sep. 30, 2023 |
Goodwill and Intangible Assets Disclosure [Abstract] |
|
Intangible Assets, Net |
Intangible Assets, NetThe following table sets forth the gross carrying amounts and related accumulated amortization of intangibles assets (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | September 30, 2023 | | December 31, 2022 | | | | (unaudited) | | | | | | | | Remaining Weighted Average Life (Years) | | Carrying Amount, Gross | | Accumulated Amortization | | Carrying Amount, Net | | Carrying Amount, Gross | | Accumulated Amortization | | Carrying Amount, Net | Acquired in-process research and development | | | $ | 124,000 | | | $ | — | | | $ | 124,000 | | | $ | 124,000 | | | $ | — | | | $ | 124,000 | | Intangible assets subject to amortization: | | | | | | | | | | | | | | Acquired developed technology and product rights | 7.08 | | 681,500 | | | (171,191) | | | 510,309 | | | 681,500 | | | (113,061) | | | 568,439 | | Capitalized patent defense costs | 0.92 | | 43,820 | | | (36,982) | | | 6,838 | | | 43,820 | | | (33,796) | | | 10,024 | | Total intangible assets | 7.00 | | $ | 849,320 | | | $ | (208,173) | | | $ | 641,147 | | | $ | 849,320 | | | $ | (146,857) | | | $ | 702,463 | |
Amortization expense for intangible assets was approximately $21.2 million and $61.3 million, for the three and nine months ended September 30, 2023 and approximately $20.6 million and $61.9 million for the three and nine months ended September 30, 2022, respectively. U.S. patents covering Trokendi XR and Oxtellar XR will expire no earlier than 2027. In regard to Trokendi XR, the Company entered into settlement agreements that allowed third parties to enter the market on January 1, 2023. In regard to Oxtellar XR, the Company entered into settlement and license agreements that allows a third party to enter the market in September 2024, or sooner under certain conditions.
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v3.23.3
Debt
|
9 Months Ended |
Sep. 30, 2023 |
Debt Disclosure [Abstract] |
|
Debt |
Debt Convertible Senior Notes Due 2023 The 0.625% Convertible Senior Notes Due 2023 (2023 Notes), which were issued in March 2018, bore interest at an annual rate of 0.625%, payable semi-annually in arrears on April 1 and October 1 of each year. The 2023 Notes matured on April 1, 2023. On March 30, 2023, the Company transferred funds totaling $403.8 million to the Trustee (Wilmington Trust) related to the repayment of the 2023 Notes which was reported as restricted cash in the first quarter of 2023. On April 1, 2023, the Company paid the total principal amount due of $402.5 million under the 2023 Notes and the remaining outstanding interest due of $1.3 million with the restricted cash. Contemporaneous with the issuance of the 2023 Notes, the Company also entered into separate privately negotiated convertible note hedge transactions (collectively, the Convertible Note Hedge Transactions) with each of the call spread counterparties. The Company issued 402,500 convertible note hedge options. As of March 31, 2023, the Convertible Note Hedges have expired. Concurrently with entering into the Convertible Note Hedge Transactions, the Company also entered into separate privately negotiated warrant transactions (collectively, the Warrant Transactions) with each of the call spread counterparties. The Company issued a total of 6,783,939 warrants. The warrants entitle the holder to one share per warrant. The strike price of the Warrant Transactions will initially be $80.91 per share of the Company’s common stock, and is subject to adjustment. The Warrant Transactions were intended to partially offset the cost to the Company of the purchased Convertible Note Hedge Transactions; however, the Warrant Transactions could have a dilutive effect with respect to the Company’s common stock, to the extent that the market price per share of the Company’s common stock, as measured under the terms of the Warrant Transactions, exceeds the strike price of the warrants. The warrants expire in tranches, if unexercised, on or before November 22, 2023. As of December 31, 2022, the liability component of the 2023 Notes consisted of the following, (dollars in thousands): | | | | | | | December 31, 2022 | | | 2023 Notes | $ | 402,500 | | Unamortized debt discount and deferred financing costs | (532) | | Total carrying value | $ | 401,968 | |
Uncommitted Demand Secured Line of Credit On February 8, 2023, the Company entered into a credit line agreement with UBS. The Credit Line provides for a revolving line of credit of up to $150 million, which can be drawn at any time. Any fixed rate borrowing will bear interest at a fixed interest rate, equal to the sum of (i) the UBS Fixed Funding Rate (as defined in the Credit Line) plus (ii) the applicable Percentage Spread established in the Credit Line. Any variable rate borrowing will bear interest at a variable interest rate, equal to the sum of (i) the UBS Variable Rate (as defined in the Credit Line) plus (ii) the applicable Percentage Spread established in the Credit Line. The Credit Line is secured by a first priority lien and security interest in certain of the Company’s assets, including each account of the Company at UBS Financial Services Inc. (the “Collateral Account”), and other such collateral (collectively, the "Collateral"), as further defined in the Credit Line. The Company may be required to post additional collateral if the value of the Collateral declines below the required collateral maintenance requirements. Upon certain customary events of default, all amounts due under the Credit Line will become immediately due and payable without demand, and UBS has the right, in its discretion, to liquidate, transfer, withdraw or sell all or any part of the Collateral and apply the proceeds to repay any borrowings pursuant to the Credit Line. The Company has the right to repay any variable rate advance under the Credit Line at any time, in whole or in part, without penalty. The Company may repay any fixed rate advance in whole, but may not repay any fixed rate advance in part. In its discretion and without cause, UBS has the right at any time to demand full or partial payment of amounts borrowed pursuant to the Credit Line and terminate the Credit Line. On March 30, 2023, the Company borrowed $93.0 million under the Credit Line, which bore a variable interest rate. The funds from this borrowing were used to repay outstanding indebtedness under the 2023 Notes as discussed above under the Convertible Senior Notes Due 2023. As of June 30, 2023, the Company repaid the total principal balance of $93.0 million under the Credit Line and the interest incurred on the Credit Line of $0.7 million. As of September 30, 2023, there was no outstanding debt under the Credit Line.
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- DefinitionThe entire disclosure for information about short-term and long-term debt arrangements, which includes amounts of borrowings under each line of credit, note payable, commercial paper issue, bonds indenture, debenture issue, own-share lending arrangements and any other contractual agreement to repay funds, and about the underlying arrangements, rationale for a classification as long-term, including repayment terms, interest rates, collateral provided, restrictions on use of assets and activities, whether or not in compliance with debt covenants, and other matters important to users of the financial statements, such as the effects of refinancing and noncompliance with debt covenants.
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v3.23.3
Share-Based Payments
|
9 Months Ended |
Sep. 30, 2023 |
Share-Based Payment Arrangement [Abstract] |
|
Share-Based Payments |
Share-Based PaymentsShare-based compensation expense is as follows (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Nine Months Ended September 30, | | 2023 | | 2022 | | 2023 | | 2022 | | (unaudited) | | (unaudited) | Research and development | $ | 1,254 | | | $ | 825 | | | $ | 3,458 | | | $ | 2,284 | | Selling, general and administrative | 6,666 | | | 4,160 | | | 16,856 | | | 11,023 | | Total | $ | 7,920 | | | $ | 4,985 | | | $ | 20,314 | | | $ | 13,307 | |
Stock Option and Stock Appreciation Rights The following table summarizes stock option and stock appreciation rights (SAR) activities: | | | | | | | | | | | | | | | | | | | Number of Options | | Weighted Average Exercise Price | | Weighted Average Remaining Contractual Term (in years) | Outstanding, December 31, 2022 | 5,797,569 | | | $ | 26.99 | | | 6.11 | Granted | 1,148,143 | | | $ | 38.28 | | | | Exercised | (228,628) | | | $ | 17.50 | | | | Forfeited | (91,986) | | | $ | 33.24 | | | | Outstanding, September 30, 2023 (unaudited) | 6,625,098 | | | $ | 29.17 | | | 6.14 | | | | | | | As of September 30, 2023 (unaudited): | | | | | | Vested and expected to vest | 6,625,098 | | | $ | 29.17 | | | 6.14 | Exercisable | 4,116,000 | | | $ | 26.44 | | | 4.65 | | | | | | | As of December 31, 2022: | | | | | | Vested and expected to vest | 5,797,569 | | | $ | 26.99 | | | 6.11 | Exercisable | 3,541,395 | | | $ | 25.08 | | | 4.68 |
Restricted Stock Units The following table summarizes restricted stock unit (RSU) activities: | | | | | | | | | | | | | Number of RSUs | | Weighted Average Grant Date Fair Value per Share | Nonvested, December 31, 2022 | 131,960 | | | $ | 32.17 | | Granted | 227,980 | | | $ | 38.60 | | Vested | (47,049) | | | $ | 32.18 | | Forfeited | (6,375) | | | $ | 34.63 | | Nonvested, September 30, 2023 (unaudited) | 306,516 | | | $ | 36.90 | |
Performance Share Units The following table summarizes performance share unit (PSU) activities: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Performance-Based Units | | Market-Based Units | | Total PSUs | | Number of PSUs | | Weighted Average Grant Date Fair Value per Share | | Number of PSUs | | Weighted Average Grant Date Fair Value per Share | | Number of PSUs | | Weighted Average Grant Date Fair Value per Share | Nonvested, December 31, 2022 | 181,750 | | | $ | 29.07 | | | 20,000 | | | $ | 28.63 | | | 201,750 | | | $ | 29.03 | | Granted | 205,000 | | | $ | 34.00 | | | — | | | $ | — | | | 205,000 | | | $ | 34.00 | | Vested | (102,520) | | | $ | 31.04 | | | — | | | $ | — | | | (102,520) | | | $ | 31.04 | | Forfeited | (3,000) | | | $ | 28.93 | | | — | | | $ | — | | | (3,000) | | | $ | 28.93 | | Nonvested, September 30, 2023 (unaudited) | 281,230 | | $ | 31.95 | | | 20,000 | | $ | 28.63 | | | 301,230 | | $ | 31.73 | |
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v3.23.3
Earnings (Loss) per Share
|
9 Months Ended |
Sep. 30, 2023 |
Earnings Per Share [Abstract] |
|
Earnings (Loss) per Share |
Earnings (Loss) per Share Basic earnings (loss) per share is calculated using the weighted average number of common shares outstanding. Diluted earnings (loss) per share is calculated using the weighted average number of common shares outstanding, including the dilutive effect of the Company’s stock option grants, SARs, RSUs, employee stock purchase plan (ESPP) awards as determined per the treasury method, and the 2023 Notes, as determined per the if-converted method. Effect of Convertible Notes and Related Convertible Note Hedges and Warrants In connection with the issuance of the 2023 Notes, the Company entered into Convertible Note Hedge and Warrant Transactions as described further in Note 8, Debt. The expected collective impact of the Convertible Note Hedge and Warrant Transactions is to reduce the potential dilution that would occur if the price of the Company's common stock was between the conversion price of $59.33 per share and the strike price of the warrants of $80.91 per share. Diluted earnings (loss) per share related to the 2023 Notes is calculated using the if-converted method. The number of dilutive shares is based on the initial conversion rate associated with the 2023 Notes. The Convertible Note Hedge and Warrant Transactions are excluded in the calculation of diluted earnings (loss) per share because inclusion would be anti-dilutive. Specifically, the denominator of the diluted earnings (loss) per share calculation excludes the additional shares related to the warrants because the average price of the Company's common stock was less than the strike price of the warrants of $80.91 per share. The Convertible Note Hedge Transactions are not considered in calculating diluted earnings (loss) per share as their impact would be anti-dilutive. In addition to the above described effect of the 2023 Notes and the related Convertible Note Hedge and Warrant Transactions, the Company also excluded the common stock equivalents of the following outstanding stock-based awards and shares associated with the conversion of the 2023 Notes in the calculation of diluted earnings (loss) per share, because their inclusion would be anti-dilutive: | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Nine Months Ended September 30, | | 2023 | | 2022 | | 2023 | | 2022 | | (unaudited) | | (unaudited) | | | | | | | | | 2023 Notes | — | | | 6,783,936 | | | 2,261,312 | | | — | | | | | | | | | | Stock options, RSUs, PSUs | 411,506 | | | 792,904 | | | 486,080 | | | 470,822 | |
The following table sets forth the computation of basic and diluted earnings (loss) per share for the three and nine months ended September 30, 2023 and 2022 under the if-converted method (dollars in thousands, except share and per share amounts):
| | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Nine Months Ended September 30, | | 2023 | | 2022 | | 2023 | | 2022 | | (unaudited) | | (unaudited) | Numerator: | | | | | | | | Net earnings (loss) | $ | (15,976) | | | $ | 1,749 | | | $ | 141 | | | $ | 35,230 | | After-tax interest expense for 2023 Notes | — | | | — | | | — | | | 2,664 | | Numerator for dilutive earnings (loss) per share | $ | (15,976) | | | $ | 1,749 | | | $ | 141 | | | $ | 37,894 | | Denominator: | | | | | | | | Weighted average shares outstanding, basic | 54,608,963 | | | 53,789,674 | | | 54,498,687 | | | 53,517,838 | | Effect of dilutive securities: | | | | | | | | Stock options, RSUs and SARs | — | | | 1,245,164 | | | 1,076,235 | | | 1,241,347 | | Convertible notes | — | | | — | | | — | | | 6,783,936 | | Weighted average shares outstanding, diluted | 54,608,963 | | | 55,034,838 | | | 55,574,922 | | | 61,543,121 | | | | | | | | | | Earnings (loss) per share, basic | $ | (0.29) | | | $ | 0.03 | | | $ | 0.00 | | | $ | 0.66 | | Earnings (loss) per share, diluted | $ | (0.29) | | | $ | 0.03 | | | $ | 0.00 | | | $ | 0.62 | |
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v3.23.3
Income Tax Expense (Benefit)
|
9 Months Ended |
Sep. 30, 2023 |
Income Tax Disclosure [Abstract] |
|
Income Tax Expense (Benefit) |
Income Tax Expense (Benefit) The following table provides information regarding the Company’s income tax expense (benefit) for the three and nine months ended September 30, 2023 and 2022 (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Nine Months Ended September 30, | | 2023 | | 2022 | | 2023 | | 2022 | | (unaudited) | | (unaudited) | Income tax expense (benefit) | $ | 25,865 | | | $ | (2,193) | | | $ | 1,638 | | | $ | (9,627) | | Effective tax rate | 261.6 | % | | 493.9 | % | | 92.1 | % | | (37.6) | % |
Income tax expense was $25.9 million for the three months ended September 30, 2023, as compared to income tax benefit of $2.2 million for the same period in the prior year. The change was primarily due to the larger pretax income in the third quarter of 2023. Income tax expense was $1.6 million for the nine months ended September 30, 2023, as compared to income tax benefit of $9.6 million for the same period in the prior year. The change was primarily due to certain tax benefits recognized with certain reorganization activities that occurred during the first quarter of 2022. The change in the effective tax rates for both the three months ended September 30, 2023 and nine months ended September 30, 2023, as compared to the same periods in prior year, were primarily due to lower pretax earnings forecasted for 2023. ASC 740, Income Taxes (ASC 740), requires an estimate of the annual effective income tax rate for the full year and apply it to pretax income (loss) for each interim period, taking into account year-to-date amounts and projected results for the full year. The annual forecasted earnings represent the Company's best estimate as of September 30, 2023 and is subject to changes, which could have a material impact on the effective tax rate in subsequent periods.
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v3.23.3
Leases
|
9 Months Ended |
Sep. 30, 2023 |
Leases [Abstract] |
|
Leases |
Leases Operating lease assets and lease liabilities as reported on the unaudited condensed consolidated balance sheets are as follows (dollars in thousands):
| | | | | | | | | | | | | | | | | | | Balance Sheet Classification | | September 30, 2023 | | December 31, 2022 | | | | (unaudited) | | | Assets | | | | | | Operating lease assets | Other assets | | $ | 29,456 | | | $ | 28,904 | | Total lease assets | | | $ | 29,456 | | | $ | 28,904 | | | | | | | | Liabilities | | | | | | Operating lease liabilities, current portion | Accounts payable and accrued liabilities | | $ | 8,480 | | | $ | 6,791 | | Operating lease liabilities, long-term | Operating lease liabilities, long-term | | 33,841 | | | 35,998 | | Total lease liabilities | | | $ | 42,321 | | | $ | 42,789 | |
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- DefinitionThe entire disclosure for operating leases of lessee. Includes, but is not limited to, description of operating lease and maturity analysis of operating lease liability.
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v3.23.3
Composition of Other Balance Sheet Items
|
9 Months Ended |
Sep. 30, 2023 |
Organization, Consolidation and Presentation of Financial Statements [Abstract] |
|
Composition of Other Balance Sheet Items |
Composition of Other Balance Sheet ItemsThe following details the composition of other balance sheet items (dollars in thousands for amounts in tables): Accounts Receivables, Net As of September 30, 2023 and December 31, 2022, the Company has reduced accounts receivable by approximately $10.8 million and $13.0 million, respectively. Prompt pay discount and contractual service fees, which were originally recorded as a reduction to revenues, represents estimated amounts not expected to be paid by our customers. The Company's customers are primarily pharmaceutical wholesalers and distributors and specialty pharmacies. Inventories | | | | | | | | | | | | | September 30, 2023 | | December 31, 2022 | | (unaudited) | | | Raw materials | $ | 21,556 | | | $ | 24,820 | | Work in process | 26,966 | | | 31,710 | | Finished goods | 34,958 | | | 35,011 | | Total | $ | 83,480 | | | $ | 91,541 | |
Property and Equipment | | | | | | | | | | | | | September 30, 2023 | | December 31, 2022 | | (unaudited) | | | Lab equipment and furniture | $ | 12,620 | | | $ | 12,127 | | Leasehold improvements | 14,023 | | | 14,023 | | Software | 883 | | | 883 | | Computer equipment | 1,078 | | | 983 | | Construction-in-progress | — | | | 206 | | | 28,604 | | | 28,222 | | Less accumulated depreciation and amortization | (14,916) | | | (13,049) | | Property and equipment, net | $ | 13,688 | | | $ | 15,173 | |
Depreciation and amortization expense on property and equipment was approximately $0.6 million and $1.9 million for the three and nine months ended September 30, 2023, and approximately $0.8 million and $2.2 million for the three and nine months ended September 30, 2022, respectively. Accounts Payable and Accrued Liabilities | | | | | | | | | | | | | September 30, 2023 | | December 31, 2022 | | (unaudited) | | | Accounts payable | $ | 3,389 | | | $ | 10,543 | | Accrued compensation, benefits, & related accruals | 19,025 | | | 16,963 | | Accrued sales & marketing | 11,656 | | | 16,783 | | Accrued R&D expenses | 9,659 | | | 7,490 | | Accrued manufacturing expenses | 9,569 | | | 15,216 | | Accrued royalties (1) | 8,852 | | | 12,022 | | Operating lease liabilities, current portion (2) | 8,480 | | | 6,791 | | Other accrued expenses | 7,841 | | | 10,534 | | Total | $ | 78,471 | | | $ | 96,342 | |
_______________________________ (1) Refer to Note 15, Commitments and Contingencies. (2) Refer to Note 12, Leases. Accrued Product Returns and Rebates | | | | | | | | | | | | | September 30, 2023 | | December 31, 2022 | | (unaudited) | | | Accrued product rebates | $ | 108,129 | | | $ | 106,657 | | Accrued product returns | 54,344 | | | 45,008 | | Total | $ | 162,473 | | | $ | 151,665 | |
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v3.23.3
Interest Expense
|
9 Months Ended |
Sep. 30, 2023 |
Other Income and Expenses [Abstract] |
|
Interest Expense |
Interest Expense The following details the composition of interest expense (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Nine Months Ended September 30, | | 2023 | | 2022 | | 2023 | | 2022 | | (unaudited) | | (unaudited) | Interest expense | $ | — | | | $ | (629) | | | $ | (1,321) | | | $ | (1,906) | | Noncash interest expense on nonrecourse liability related to sale of future royalties | — | | | (566) | | | (562) | | | (1,988) | | Noncash interest expense on debt | — | | | (529) | | | (532) | | | (1,582) | | Total | $ | — | | | $ | (1,724) | | | $ | (2,415) | | | $ | (5,476) | |
Noncash interest expense on debt is related to amortization of deferred financing costs on the 2023 Notes. The Company fully amortized the deferred financing costs on the 2023 Notes in the first quarter of 2023.
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v3.23.3
Commitments and Contingencies
|
9 Months Ended |
Sep. 30, 2023 |
Commitments and Contingencies Disclosure [Abstract] |
|
Commitments and Contingencies |
Commitments and Contingencies Product Licenses The Company has obtained exclusive licenses from third parties for proprietary rights to support the product candidates in the Company's CNS portfolio. Under these license agreements, the Company may be required to pay certain amounts upon the achievement of defined milestones. If these products are ultimately commercialized, the Company is also obligated to pay royalties to third parties, computed as a percentage of net product sales, for each respective product under a license agreement. Through the USWM Acquisition, the Company acquired licensing agreements with other pharmaceutical companies for APOKYN, XADAGO, and MYOBLOC. The Company is obligated to pay royalties to third parties, computed as a percentage of net product sales, for each of the products under the respective license agreements. The royalty expense incurred for these acquired products is recognized as Cost of goods sold in the unaudited condensed consolidated statements of earnings (loss). Royalty Agreement In the third quarter of 2014, the Company received $30 million pursuant to a Royalty Interest Acquisition Agreement related to the purchase by HC Royalty of certain of the Company's rights under the Company's agreement with United Therapeutics related to the commercialization of Orenitram (treprostinil) Extended-Release Tablets. Full ownership of the royalty rights have reverted back to the Company as the cumulative payment threshold has been reached as of June 30, 2023 (see Note 3, Disaggregated Revenues). As of December 31, 2022, the nonrecourse liability related to the sale of future royalties was $6.0 million and was included in Other current liabilities as reported on the condensed consolidated balance sheet. USWM Enterprise Commitments Assumed As part of the USWM Acquisition, the Company assumed the remaining commitments of USWM Enterprises and its subsidiaries, which are discussed below. The Company assumed the annual minimum purchase requirement of MYOBLOC, amounting to an estimated €3.9 million annually, under the contract manufacturing agreement with Merz for manufacture and supply. MDD US Operations, LLC (formerly US WorldMeds, LLC) and its subsidiary, Solstice Neurosciences, LLC (US) (collectively, the MDD Subsidiaries) entered into a Corporate Integrity Agreement (CIA) with the Office of Inspector General of the U.S. Department of Health and Human Services which was effective in April 2019. Under the CIA, the MDD Subsidiaries agreed to and paid $17.5 million to resolve U.S. Department of Justice allegations that it violated the False Claims Act and committed to the establishment and ongoing maintenance of an effective compliance program. The fine was paid by the MDD Subsidiaries prior to closing of the USWM Acquisition. As part of the USWM Acquisition, the Company assumed the obligations of the CIA and could become liable for payment of certain stipulated monetary penalties in the event of any CIA violations. In addition, the Company will continue to maintain a broad array of processes, policies and procedures necessary to comply with the CIA through March 2024. Data Breach-related Contingency On November 24, 2021, the Company announced that we were the target of a ransomware attack. The attack had no significant impact on our business and did not cause any long-term disruption to our operations. Based on its internal investigation, the Company believes the criminal ransomware groups ("criminal groups") copied certain data from our systems, encrypted certain data on the Company's systems, and then deployed malware designed to impede access to our systems. Thereafter the criminal groups contacted the Company and threatened to publish certain data copied from the Company's systems. Upon detection of the ransomware attack, the Company notified government authorities, engaged third-party cybersecurity experts through our outside counsel, and commenced its recovery process. The Company maintains redundant off-site data backups, which were verified to have not been compromised by the ransomware attack and were utilized to restore the data encrypted by the criminal groups. In the fourth quarter of 2021, the Company had successfully recovered the impacted files and took additional steps designed to further protect its networks and files. Furthermore, while the Company has not been the subject of any legal proceedings involving the attack, the likelihood that the Company could be the subject of claims from persons alleging they suffered damages from the incident, or actions by governmental authorities is possible, but the amount of such fines, penalties or costs, if any, cannot be estimated at this time. The Company continues to monitor the situation. Claims and Litigation From time to time, the Company may be involved in various claims, litigation and legal proceedings. These matters may involve patent litigation, product liability and other product-related litigation, commercial and other matters, and government investigations, among others. On a quarterly basis, the Company reviews the status of each significant matter and assesses its potential financial exposure. If the potential loss from any claim, asserted or unasserted, or legal proceeding is considered probable and the amount can be reasonably estimated, the Company will accrue a liability for the estimated loss. Because of uncertainties related to claims, legal proceedings and litigation, accruals will be based on the Company's best estimates based on available information. The Company does not believe that any of these matters will have a material adverse effect on our financial position. The Company may reassess the potential liability related to these matters and may revise these estimates. The process of resolving matters through litigation or other means is inherently uncertain and it is possible that an unfavorable resolution of these matters will adversely affect the Company, its results of operations, financial condition and cash flows. NAMENDA XR/Namzaric Qui Tam Litigation On April 1, 2019, Adamas was served with a complaint filed in the United States District Court for the Northern District of California (the District Court) (Case No. 3:18-cv-03018-JCS) against it and several Allergan entities alleging violations of federal and state false claims acts (FCA) in connection with the commercialization of NAMENDA XR and Namzaric by Allergan. The lawsuit is a qui tam complaint brought by an individual, asserting rights of the federal government and various state governments. The lawsuit was originally filed in May 2018 under seal, and Adamas became aware of the lawsuit when it was served. The complaint alleges that patents held by Allergan and Adamas covering NAMENDA XR and Namzaric were procured through fraud on the United States Patent and Trademark Office and that these patents were asserted against potential generic manufacturers of NAMENDA XR and Namzaric to prevent the generic manufacturers from entering the market, thereby wrongfully excluding generic competition resulting in artificially high price being charged to government payors. Adamas' patents in question were licensed exclusively to Forest Laboratories Holdings Limited. The complaint includes a claim for damages of "potentially more than $2.5 billion dollars," treble damages and statutory penalties. To date the federal and state governments have declined to intervene in this action. This case is currently stayed pending Adamas's and Allergan's interlocutory appeal of the District Court's December 11, 2020 order denying Adamas's and Allergan's motion to dismiss the complaint. The appeal was heard by the United States Court of Appeals for the Ninth Circuit (Case No. 21-80005). Argument was held on January 10, 2022. On August 25, 2022, the Ninth Circuit sided with the defendants by reversing the District Court’s public disclosure bar rulings and remanding the case back to the District Court to decide certain issues in the first instance. On October 11, 2022, the plaintiff filed a petition for rehearing with the Ninth Circuit which was denied on November 3, 2022. On December 23, 2022, the defendants filed renewed motions to dismiss directed to the remaining unresolved issue. On March 20, 2023, the District Court entered an order and final judgment dismissing with prejudice Silbersher’s Federal False Claims Act claim while declining to exercise supplemental jurisdiction over the state false claims act claims which were dismissed without prejudice. On April 19, 2023, the plaintiff appealed the District Court's dismissal of the Federal False Claims Act claim. APOKYN Litigation On October 3, 2022, Sage Chemical, Inc. and TruPharma, LLC filed a lawsuit in the United States District Court for the District of Delaware (Case No.22-cv-1302) alleging that Supernus Pharmaceuticals, Inc., Britannia Pharmaceuticals Limited, and US WorldMeds Partners, LLC violated state and federal antitrust law in connection with APOKYN. On January 10, 2023, the Company filed motions to dismiss all claims. On January 25, 2023, Defendants filed a motion to stay discovery and stay the deadline to submit a proposed scheduling order pending resolutions of Defendants’ motions to dismiss. On March 7, 2023, the Court denied the Company's motion to stay and ordered that the parties commence discovery. On April 10, 2023, the Court issued a scheduling order that provides for a Pretrial Conference on March 7, 2025 and a jury trial beginning on March 24, 2025. Pretrial discovery is ongoing as the date of this letter. The Company intends to defend itself vigorously. However, the Company can offer no assurances that it will be successful in a litigation. Apotex Settlement and License Agreements The Company entered into a settlement and license agreements dated June 21, 2023 with Apotex Inc. to settle ongoing patent litigation regarding Apotex ANDA filings seeking approval to market a generic version of the Company's 150mg, 300mg, and 600mg strength Oxtellar XR (extended-release oxcarbazepine) tablets in September 2024, or sooner under certain conditions.
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v3.23.3
Subsequent Events
|
9 Months Ended |
Sep. 30, 2023 |
Subsequent Events [Abstract] |
|
Subsequent Events |
Subsequent Events In October 2023, the Company resubmitted its New Drug Application (NDA) for its apomorphine infusion device (SPN-830) for the continuous treatment of motor fluctuations ("off" episodes) in Parkinson’s disease. In November 2023. the FDA accepted the resubmission of the NDA for SPN-830. The NDA is now considered filed, with a user fee goal date (PDUFA date) of April 5, 2024.
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v3.23.3
Pay vs Performance Disclosure - USD ($) $ in Thousands |
3 Months Ended |
9 Months Ended |
Sep. 30, 2023 |
Jun. 30, 2023 |
Mar. 31, 2023 |
Sep. 30, 2022 |
Jun. 30, 2022 |
Mar. 31, 2022 |
Sep. 30, 2023 |
Sep. 30, 2022 |
Pay vs Performance Disclosure |
|
|
|
|
|
|
|
|
Net earnings (loss) |
$ (15,976)
|
$ (831)
|
$ 16,948
|
$ 1,749
|
$ 7,865
|
$ 25,616
|
$ 141
|
$ 35,230
|
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- DefinitionThe portion of profit or loss for the period, net of income taxes, which is attributable to the parent.
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v3.23.3
Insider Trading Arrangements
|
3 Months Ended |
9 Months Ended |
Sep. 30, 2023
shares
|
Sep. 30, 2023
shares
|
Trading Arrangements, by Individual |
|
|
Material Terms of Trading Arrangement |
|
During the quarter, the following trading arrangements were adopted or terminated as indicated below: | | | | | | | | | | | | | | | | | | | | | Name and Title of Director or Officer | Rule 10b5-1 Trading Arrangement(1) | Trading Arrangement Adopted or Terminated | Date of Adoption or Termination | Duration of Trading Arrangement | Aggregate Number of Securities to be Purchased Pursuant to Trading Arrangement | Aggregate Number of Securities to be Sold Pursuant to Trading Arrangement | Jack Khattar, President, Chief Executive Officer and Director | Yes | Adopted | August 27, 2023 | First Transaction Date(1) through March 3, 2025 | 75,037 | 75,037(2) | Padmanabh P. Bhatt, Ph.D, Senior Vice President of Intellectual Property and Chief Scientific Officer | Yes | Adopted | September 7, 2023 | First Transaction Date(1) through April 30, 2024 | 109,250 | 109,250(2) |
___________________________________________ (1) First Transaction Date means the date that is the later of (i) the 91st day after the Date of Adoption, or (ii) the earlier of: (a) the third business day following the disclosure of the Company’s financial results in a Form 10-Q or Form 10-K for the completed fiscal quarter in which the trading arrangement was adopted, or (b) the 121st day after the Date of Adoption. (2) This trading arrangement covers the exercise and sale of stock options, with a portion of such sales limited to an amount reasonably estimated such that the net proceeds from the sale are sufficient to cover the exercise cost and taxes associated with the exercise of the stock options.
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Rule 10b5-1 Arrangement Terminated |
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|
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Non-Rule 10b5-1 Arrangement Terminated |
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|
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Jack Khattar [Member] |
|
|
Trading Arrangements, by Individual |
|
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Name |
Jack Khattar
|
|
Title |
President, Chief Executive Officer and Director
|
|
Rule 10b5-1 Arrangement Adopted |
true
|
|
Adoption Date |
August 27, 2023
|
|
Arrangement Duration |
554 days
|
|
Aggregate Available |
75,037
|
75,037
|
Padmanabh P. Bhatt [Member] |
|
|
Trading Arrangements, by Individual |
|
|
Name |
Padmanabh P. Bhatt, Ph.D
|
|
Title |
Senior Vice President of Intellectual Property and Chief Scientific Officer
|
|
Rule 10b5-1 Arrangement Adopted |
true
|
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Adoption Date |
September 7, 2023
|
|
Arrangement Duration |
236 days
|
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Aggregate Available |
109,250
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109,250
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v3.23.3
Summary of Significant Accounting Policies (Policies)
|
9 Months Ended |
Sep. 30, 2023 |
Accounting Policies [Abstract] |
|
Basis of Presentation |
Basis of Presentation The Company’s unaudited condensed consolidated financial statements have been prepared in accordance with the requirements of the U.S. Securities and Exchange Commission (SEC) for interim financial information. As permitted under Generally Accepted Accounting Principles in the United States (U.S. GAAP), certain notes and other information have been omitted from the interim unaudited condensed consolidated financial statements presented in this Quarterly Report on Form 10-Q. Therefore, these unaudited condensed consolidated financial statements should be read in conjunction with the Company’s most recent Annual Report on Form 10-K, for the year ended December 31, 2022, filed with the SEC. In management’s opinion, the unaudited condensed consolidated financial statements include all normal and recurring adjustments necessary for a fair presentation of the Company’s financial position, results of operations, and cash flows. The results of operations for any interim period are not necessarily indicative of the Company’s future quarterly or annual results. The Company, which is primarily located in the U.S., operates in one operating segment.
|
Consolidation |
Consolidation The Company's unaudited condensed consolidated financial statements include the accounts of Supernus Pharmaceuticals, Inc. and its wholly owned subsidiaries. These are collectively referred to herein as "Supernus" or "the Company." Supernus Pharmaceuticals, Inc. and each of its subsidiaries are distinct legal entities. All significant intercompany transactions and balances have been eliminated in consolidation. The unaudited condensed consolidated financial statements reflect the consolidation of entities in which the Company has a controlling financial interest. In determining whether there is a controlling financial interest, the Company considers if it has a majority of the voting interests of the entity, or if the entity is a variable interest entity (VIE) and if the Company is the primary beneficiary. In determining the primary beneficiary of a VIE, the Company evaluates whether it has both: the power to direct the activities of the VIE that most significantly impact the VIE's economic performance; and the obligation to absorb losses of, or the right to receive benefits from the VIE that could potentially be significant to that VIE. The Company's judgment with respect to its level of influence or control of an entity involves the consideration of various factors, including the form of an ownership interest; representation in the entity's governance; the size of the investment; estimates of future cash flows; the ability to participate in policymaking decisions; and the rights of the other investors to participate in the decision making process, including the right to liquidate the entity, if applicable. If the Company is not the primary beneficiary of the VIE, and an ownership interest is maintained in the entity, the interest is accounted for under the equity or cost methods of accounting, as appropriate. The Company continuously assesses whether it is the primary beneficiary of a VIE as changes to existing relationships or future transactions may affect its conclusions.
|
Use of Estimates |
Use of Estimates The Company bases its estimates on: historical experience; forecasts; information received from its service providers; information from other sources, including public and proprietary sources; and other assumptions that the Company believes are reasonable under the circumstances. Actual results could differ materially from the Company’s estimates. The Company periodically evaluates the methodologies employed in making its estimates.
|
Advertising Expense |
Advertising Expense Advertising expense includes the cost of promotional materials and activities, such as printed materials and digital marketing, marketing programs and speaker programs. The costs of the Company's advertising efforts are expensed as incurred.
|
Recently Issued Accounting Pronouncements |
Recently Issued Accounting Pronouncements Accounting Pronouncements Adopted Accounting Standards Update (ASU) 2020-06, Debt - Debt with Conversion and Other Options (Subtopic 470-20) and Derivatives and Hedging - Contracts in Entity's Own Equity (Subtopic 815-40): Accounting for Convertible Instruments and Contracts in an Entity's Own Equity - The new standard, issued in August 2020, simplifies the accounting for certain financial instruments with characteristics of liabilities and equity, including convertible debt instruments with cash conversion and beneficial conversion features. ASU 2020-06 eliminates requirements to separately account for liability and equity components of such convertible debt instruments and eliminates the ability to use the treasury stock method for calculating diluted earnings per share for convertible instruments whose principal amount may be settled in whole or in part with equity. Instead, ASU 2020-06 requires (i) the entire amount of the security to be presented as a liability on the balance sheet and (ii) application of the “if-converted” method for calculating diluted earnings per share. This new standard also removes certain settlement conditions required for equity contracts to qualify for the derivative scope exception. The Company adopted the new guidance as of January 1, 2022 using the modified retrospective method of transition which allows for a cumulative-effect adjustment to the opening balance of retained earnings in the period of adoption. As a result, the cumulative effect of the accounting change increased the carrying amount of the convertible notes, net by $20.6 million, increased retained earnings by $40.6 million, reduced additional paid-in capital by $56.2 million, and decreased deferred tax liabilities by $5.0 million as of January 1, 2022. Upon adoption, the Company began calculating diluted earnings per share under the if-converted method.
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v3.23.3
Disaggregated Revenues (Tables)
|
9 Months Ended |
Sep. 30, 2023 |
Disaggregation of Revenue [Abstract] |
|
Summary of disaggregation of revenues by nature |
The following table summarizes the disaggregation of revenues by product or source, (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Nine Months Ended September 30, | | 2023 | | 2022 | | 2023 | | 2022 | | (unaudited) | | (unaudited) | Net product sales | | | | | | | | Qelbree | $ | 37,081 | | | $ | 18,326 | | | $ | 93,840 | | | $ | 37,708 | | GOCOVRI | 32,889 | | | 27,878 | | | 87,650 | | | 75,179 | | Oxtellar XR | 29,644 | | | 30,528 | | | 82,359 | | | 88,007 | | Trokendi XR | 20,625 | | | 69,599 | | | 74,734 | | | 204,033 | | APOKYN | 21,510 | | | 18,261 | | | 56,324 | | | 57,156 | | Other(1) | 7,255 | | | 8,132 | | | 23,008 | | | 23,564 | | Total net product sales | $ | 149,004 | | | $ | 172,724 | | | $ | 417,915 | | | $ | 485,647 | | Royalty revenues | 4,876 | | | 4,629 | | | 25,292 | | | 14,263 | | Total revenues | $ | 153,880 | | | $ | 177,353 | | | $ | 443,207 | | | $ | 499,910 | |
___________________________________________ (1) Includes net product sales of MYOBLOC, XADAGO and Osmolex ER. The decrease in Trokendi XR net product sales for the three and nine months ended September 30, 2023, compared to the same period in 2022 was primarily attributable to the loss of exclusivity with generic entrants in January 2023. The following table shows the percentage of net product sales to total net product sales: | | | | | | | | | | | | | | | | | | | | | | | | | Percentage of Net Product Sales | | Three Months Ended September 30, | | Nine Months Ended September 30, | | 2023 | | 2022 | | 2023 | | 2022 | Qelbree | 25% | | 11% | | 22% | | 8% | GOCOVRI | 22% | | 16% | | 21% | | 15% | Oxtellar XR | 20% | | 18% | | 20% | | 18% | Trokendi XR | 14% | | 40% | | 18% | | 42% | APOKYN | 14% | | 10% | | 13% | | 12% | Other(1) | 5% | | 5% | | 6% | | 5% | Total | 100% | | 100% | | 100% | | 100% | ___________________________________________(1) Includes net product sales of MYOBLOC, XADAGO and Osmolex ER.
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v3.23.3
Investments (Tables)
|
9 Months Ended |
Sep. 30, 2023 |
Investments, Debt and Equity Securities [Abstract] |
|
Schedule of unrestricted available-for-sale marketable securities |
Unrestricted available-for-sale marketable securities held by the Company are as follows, (dollars in thousands): | | | | | | | | | | | | | September 30, 2023 | | December 31, 2022 | | (unaudited) | | | Corporate and municipal debt securities | | | | Amortized cost | $ | 131,891 | | | $ | 466,333 | | Gross unrealized gains | 1 | | | 14 | | Gross unrealized losses | (1,563) | | | (4,237) | | Total fair value | $ | 130,329 | | | $ | 462,110 | |
|
Schedule of contractual maturities of the unrestricted available-for-sale marketable securities held |
The contractual maturities of the unrestricted available-for-sale marketable securities held by the Company are as follows, (dollars in thousands): | | | | | | | September 30, 2023 | | (unaudited) | Less than 1 year | $ | 105,204 | | 1 year to 2 years | 25,125 | | | | | | | | Total | $ | 130,329 | |
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v3.23.3
Fair Value of Financial Measurements (Tables)
|
9 Months Ended |
Sep. 30, 2023 |
Fair Value Disclosures [Abstract] |
|
Schedule of fair value of the financial assets and liabilities |
The Company’s financial assets that are required to be measured at fair value on a recurring basis are as follows (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | | | Fair Value Measurements as of September 30, 2023 (unaudited) | | Total Fair Value as of September 30, 2023 (unaudited) | | Level 1 | | Level 2 | | Level 3 | Assets: | | | | | | | | Cash and cash equivalents | | | | | | | | Cash | $ | 38,302 | | | $ | 38,302 | | | $ | — | | | $ | — | | Money market securities and funds | 56,683 | | | 56,683 | | | — | | | — | | Marketable securities | | | | | | | | Corporate and municipal debt securities | 105,204 | | | — | | | 105,204 | | | — | | | | | | | | | | Long-term marketable securities | | | | | | | | Corporate and municipal debt securities | 25,125 | | | — | | | 25,125 | | | — | | | | | | | | | | Other assets | | | | | | | | Marketable securities - restricted (SERP) | 512 | | | 14 | | | 498 | | | — | | Total assets at fair value | $ | 225,826 | | | $ | 94,999 | | | $ | 130,827 | | | $ | — | | Liabilities: | | | | | | | | Contingent consideration | $ | 53,654 | | | $ | — | | | $ | — | | | $ | 53,654 | | Total liabilities at fair value | $ | 53,654 | | | $ | — | | | $ | — | | | $ | 53,654 | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | Fair Value Measurements as of December 31, 2022 | | Total Fair Value as of December 31, 2022 | | Level 1 | | Level 2 | | Level 3 | Assets: | | | | | | | | Cash and cash equivalents | | | | | | | | Cash | $ | 52,181 | | | $ | 52,181 | | | $ | — | | | $ | — | | Money market securities and funds | 40,939 | | | 40,939 | | | — | | | — | | Marketable securities | | | | | | | | Corporate and municipal debt securities | 368,214 | | | — | | | 368,214 | | | — | | | | | | | | | | Long-term marketable securities | | | | | | | | Corporate and municipal debt securities | 93,896 | | | — | | | 93,896 | | | — | | | | | | | | | | Other assets | | | | | | | | Marketable securities - restricted (SERP) | 496 | | | 11 | | | 485 | | | — | | Total assets at fair value | $ | 555,726 | | | $ | 93,131 | | | $ | 462,595 | | | $ | — | | Liabilities: | | | | | | | | Contingent consideration | $ | 54,967 | | | $ | — | | | $ | — | | | $ | 54,967 | | Total liabilities at fair value | $ | 54,967 | | | $ | — | | | $ | — | | | $ | 54,967 | |
|
Schedule of financial liabilities that are not carried at fair value |
As of December 31, 2022, the carrying value and fair value of the 2023 Notes which were not carried at fair value was as follows (dollars in thousands): | | | | | | | | | | | | | December 31, 2022 | | Carrying Value | | Fair Value (Level 2) | | | | | Convertible notes, net | $ | 401,968 | | | $ | 395,959 | |
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v3.23.3
Contingent Consideration (Tables)
|
9 Months Ended |
Sep. 30, 2023 |
Business Combination and Asset Acquisition [Abstract] |
|
Schedule of business acquisitions by acquisition, contingent consideration |
The following table provides the current and long-term portions related to the contingent consideration for the USWM Acquisition and Adamas Acquisition (dollars in thousands): | | | | | | | | | | | | | September 30, 2023 | | December 31, 2022 | Reported under the following captions in the condensed consolidated balance sheets: | (unaudited) | | | Contingent consideration, current portion | $ | 45,880 | | | $ | 21,120 | | Contingent consideration, long-term | 7,774 | | | 33,847 | | Total | $ | 53,654 | | | $ | 54,967 | |
|
Reconciliation of the beginning and ending balances related to the contingent consideration |
The following tables provide a reconciliation of the beginning and ending balances related to the contingent consideration for the USWM Acquisition and Adamas Acquisition (dollars in thousands): | | | | | | | | | | | | | | | | | | | USWM Acquisition | | Adamas Acquisition | | Total | Balance at December 31, 2022 | $ | 46,270 | | | $ | 8,697 | | | $ | 54,967 | | Change in fair value recognized in earnings | (1,710) | | | 63 | | | (1,647) | | Balance at March 31, 2023 (unaudited) | 44,560 | | | 8,760 | | | 53,320 | | Change in fair value recognized in earnings | 660 | | | 130 | | | 790 | | Balance at June 30, 2023 (unaudited) | 45,220 | | | 8,890 | | | 54,110 | | Change in fair value recognized in earnings | 660 | | | (1,116) | | | (456) | | Balance at September 30, 2023 (unaudited) | $ | 45,880 | | | $ | 7,774 | | | $ | 53,654 | |
| | | | | | | | | | | | | | | | | | | USWM Acquisition | | Adamas Acquisition | | Total | Balance at December 31, 2021 | $ | 70,170 | | | $ | 10,307 | | | $ | 80,477 | | Milestone payments | (25,000) | | | — | | | (25,000) | | Change in fair value recognized in earnings | 1,720 | | | (1,055) | | | 665 | | Balance at March 31, 2022 (unaudited) | 46,890 | | | 9,252 | | | 56,142 | | Change in fair value recognized in earnings | 350 | | | 393 | | | 743 | | Balance at June 30, 2022 (unaudited) | 47,240 | | | 9,645 | | | 56,885 | | Change in fair value recognized in earnings | 350 | | | 136 | | | 486 | | Balance at September 30, 2022 (unaudited) | $ | 47,590 | | | $ | 9,781 | | | $ | 57,371 | |
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v3.23.3
Intangible Assets, Net (Tables)
|
9 Months Ended |
Sep. 30, 2023 |
Goodwill and Intangible Assets Disclosure [Abstract] |
|
Schedule of Intangible Assets |
The following table sets forth the gross carrying amounts and related accumulated amortization of intangibles assets (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | September 30, 2023 | | December 31, 2022 | | | | (unaudited) | | | | | | | | Remaining Weighted Average Life (Years) | | Carrying Amount, Gross | | Accumulated Amortization | | Carrying Amount, Net | | Carrying Amount, Gross | | Accumulated Amortization | | Carrying Amount, Net | Acquired in-process research and development | | | $ | 124,000 | | | $ | — | | | $ | 124,000 | | | $ | 124,000 | | | $ | — | | | $ | 124,000 | | Intangible assets subject to amortization: | | | | | | | | | | | | | | Acquired developed technology and product rights | 7.08 | | 681,500 | | | (171,191) | | | 510,309 | | | 681,500 | | | (113,061) | | | 568,439 | | Capitalized patent defense costs | 0.92 | | 43,820 | | | (36,982) | | | 6,838 | | | 43,820 | | | (33,796) | | | 10,024 | | Total intangible assets | 7.00 | | $ | 849,320 | | | $ | (208,173) | | | $ | 641,147 | | | $ | 849,320 | | | $ | (146,857) | | | $ | 702,463 | |
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v3.23.3
Debt (Tables)
|
9 Months Ended |
Sep. 30, 2023 |
Debt Disclosure [Abstract] |
|
Summary of liability component of 2023 Notes |
As of December 31, 2022, the liability component of the 2023 Notes consisted of the following, (dollars in thousands): | | | | | | | December 31, 2022 | | | 2023 Notes | $ | 402,500 | | Unamortized debt discount and deferred financing costs | (532) | | Total carrying value | $ | 401,968 | |
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v3.23.3
Share-Based Payments (Tables)
|
9 Months Ended |
Sep. 30, 2023 |
Share-Based Payment Arrangement [Abstract] |
|
Schedule of share-based compensation expense |
Share-based compensation expense is as follows (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Nine Months Ended September 30, | | 2023 | | 2022 | | 2023 | | 2022 | | (unaudited) | | (unaudited) | Research and development | $ | 1,254 | | | $ | 825 | | | $ | 3,458 | | | $ | 2,284 | | Selling, general and administrative | 6,666 | | | 4,160 | | | 16,856 | | | 11,023 | | Total | $ | 7,920 | | | $ | 4,985 | | | $ | 20,314 | | | $ | 13,307 | |
|
Summary of stock options and SAR activities |
The following table summarizes stock option and stock appreciation rights (SAR) activities: | | | | | | | | | | | | | | | | | | | Number of Options | | Weighted Average Exercise Price | | Weighted Average Remaining Contractual Term (in years) | Outstanding, December 31, 2022 | 5,797,569 | | | $ | 26.99 | | | 6.11 | Granted | 1,148,143 | | | $ | 38.28 | | | | Exercised | (228,628) | | | $ | 17.50 | | | | Forfeited | (91,986) | | | $ | 33.24 | | | | Outstanding, September 30, 2023 (unaudited) | 6,625,098 | | | $ | 29.17 | | | 6.14 | | | | | | | As of September 30, 2023 (unaudited): | | | | | | Vested and expected to vest | 6,625,098 | | | $ | 29.17 | | | 6.14 | Exercisable | 4,116,000 | | | $ | 26.44 | | | 4.65 | | | | | | | As of December 31, 2022: | | | | | | Vested and expected to vest | 5,797,569 | | | $ | 26.99 | | | 6.11 | Exercisable | 3,541,395 | | | $ | 25.08 | | | 4.68 |
|
Summary of restricted stock units |
The following table summarizes restricted stock unit (RSU) activities: | | | | | | | | | | | | | Number of RSUs | | Weighted Average Grant Date Fair Value per Share | Nonvested, December 31, 2022 | 131,960 | | | $ | 32.17 | | Granted | 227,980 | | | $ | 38.60 | | Vested | (47,049) | | | $ | 32.18 | | Forfeited | (6,375) | | | $ | 34.63 | | Nonvested, September 30, 2023 (unaudited) | 306,516 | | | $ | 36.90 | |
|
Summary of performance stock unit |
The following table summarizes performance share unit (PSU) activities: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Performance-Based Units | | Market-Based Units | | Total PSUs | | Number of PSUs | | Weighted Average Grant Date Fair Value per Share | | Number of PSUs | | Weighted Average Grant Date Fair Value per Share | | Number of PSUs | | Weighted Average Grant Date Fair Value per Share | Nonvested, December 31, 2022 | 181,750 | | | $ | 29.07 | | | 20,000 | | | $ | 28.63 | | | 201,750 | | | $ | 29.03 | | Granted | 205,000 | | | $ | 34.00 | | | — | | | $ | — | | | 205,000 | | | $ | 34.00 | | Vested | (102,520) | | | $ | 31.04 | | | — | | | $ | — | | | (102,520) | | | $ | 31.04 | | Forfeited | (3,000) | | | $ | 28.93 | | | — | | | $ | — | | | (3,000) | | | $ | 28.93 | | Nonvested, September 30, 2023 (unaudited) | 281,230 | | $ | 31.95 | | | 20,000 | | $ | 28.63 | | | 301,230 | | $ | 31.73 | |
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v3.23.3
Earnings (Loss) per Share (Tables)
|
9 Months Ended |
Sep. 30, 2023 |
Earnings Per Share [Abstract] |
|
Schedule of common stock equivalents excluded in the calculation of diluted earnings per share |
In addition to the above described effect of the 2023 Notes and the related Convertible Note Hedge and Warrant Transactions, the Company also excluded the common stock equivalents of the following outstanding stock-based awards and shares associated with the conversion of the 2023 Notes in the calculation of diluted earnings (loss) per share, because their inclusion would be anti-dilutive: | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Nine Months Ended September 30, | | 2023 | | 2022 | | 2023 | | 2022 | | (unaudited) | | (unaudited) | | | | | | | | | 2023 Notes | — | | | 6,783,936 | | | 2,261,312 | | | — | | | | | | | | | | Stock options, RSUs, PSUs | 411,506 | | | 792,904 | | | 486,080 | | | 470,822 | |
|
Schedule of computation of basic and diluted earnings per share |
The following table sets forth the computation of basic and diluted earnings (loss) per share for the three and nine months ended September 30, 2023 and 2022 under the if-converted method (dollars in thousands, except share and per share amounts):
| | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Nine Months Ended September 30, | | 2023 | | 2022 | | 2023 | | 2022 | | (unaudited) | | (unaudited) | Numerator: | | | | | | | | Net earnings (loss) | $ | (15,976) | | | $ | 1,749 | | | $ | 141 | | | $ | 35,230 | | After-tax interest expense for 2023 Notes | — | | | — | | | — | | | 2,664 | | Numerator for dilutive earnings (loss) per share | $ | (15,976) | | | $ | 1,749 | | | $ | 141 | | | $ | 37,894 | | Denominator: | | | | | | | | Weighted average shares outstanding, basic | 54,608,963 | | | 53,789,674 | | | 54,498,687 | | | 53,517,838 | | Effect of dilutive securities: | | | | | | | | Stock options, RSUs and SARs | — | | | 1,245,164 | | | 1,076,235 | | | 1,241,347 | | Convertible notes | — | | | — | | | — | | | 6,783,936 | | Weighted average shares outstanding, diluted | 54,608,963 | | | 55,034,838 | | | 55,574,922 | | | 61,543,121 | | | | | | | | | | Earnings (loss) per share, basic | $ | (0.29) | | | $ | 0.03 | | | $ | 0.00 | | | $ | 0.66 | | Earnings (loss) per share, diluted | $ | (0.29) | | | $ | 0.03 | | | $ | 0.00 | | | $ | 0.62 | |
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v3.23.3
Income Tax Expense (Benefit) (Tables)
|
9 Months Ended |
Sep. 30, 2023 |
Income Tax Disclosure [Abstract] |
|
Schedule of effective income tax rate reconciliation |
The following table provides information regarding the Company’s income tax expense (benefit) for the three and nine months ended September 30, 2023 and 2022 (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Nine Months Ended September 30, | | 2023 | | 2022 | | 2023 | | 2022 | | (unaudited) | | (unaudited) | Income tax expense (benefit) | $ | 25,865 | | | $ | (2,193) | | | $ | 1,638 | | | $ | (9,627) | | Effective tax rate | 261.6 | % | | 493.9 | % | | 92.1 | % | | (37.6) | % |
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v3.23.3
Leases (Tables)
|
9 Months Ended |
Sep. 30, 2023 |
Leases [Abstract] |
|
Schedule of balance sheet information related to leases |
Operating lease assets and lease liabilities as reported on the unaudited condensed consolidated balance sheets are as follows (dollars in thousands):
| | | | | | | | | | | | | | | | | | | Balance Sheet Classification | | September 30, 2023 | | December 31, 2022 | | | | (unaudited) | | | Assets | | | | | | Operating lease assets | Other assets | | $ | 29,456 | | | $ | 28,904 | | Total lease assets | | | $ | 29,456 | | | $ | 28,904 | | | | | | | | Liabilities | | | | | | Operating lease liabilities, current portion | Accounts payable and accrued liabilities | | $ | 8,480 | | | $ | 6,791 | | Operating lease liabilities, long-term | Operating lease liabilities, long-term | | 33,841 | | | 35,998 | | Total lease liabilities | | | $ | 42,321 | | | $ | 42,789 | |
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v3.23.3
Composition of Other Balance Sheet Items (Tables)
|
9 Months Ended |
Sep. 30, 2023 |
Organization, Consolidation and Presentation of Financial Statements [Abstract] |
|
Schedule of inventories |
Inventories | | | | | | | | | | | | | September 30, 2023 | | December 31, 2022 | | (unaudited) | | | Raw materials | $ | 21,556 | | | $ | 24,820 | | Work in process | 26,966 | | | 31,710 | | Finished goods | 34,958 | | | 35,011 | | Total | $ | 83,480 | | | $ | 91,541 | |
|
Schedule of property and equipment |
Property and Equipment | | | | | | | | | | | | | September 30, 2023 | | December 31, 2022 | | (unaudited) | | | Lab equipment and furniture | $ | 12,620 | | | $ | 12,127 | | Leasehold improvements | 14,023 | | | 14,023 | | Software | 883 | | | 883 | | Computer equipment | 1,078 | | | 983 | | Construction-in-progress | — | | | 206 | | | 28,604 | | | 28,222 | | Less accumulated depreciation and amortization | (14,916) | | | (13,049) | | Property and equipment, net | $ | 13,688 | | | $ | 15,173 | |
|
Schedule of accrued expenses and other current liabilities |
Accounts Payable and Accrued Liabilities | | | | | | | | | | | | | September 30, 2023 | | December 31, 2022 | | (unaudited) | | | Accounts payable | $ | 3,389 | | | $ | 10,543 | | Accrued compensation, benefits, & related accruals | 19,025 | | | 16,963 | | Accrued sales & marketing | 11,656 | | | 16,783 | | Accrued R&D expenses | 9,659 | | | 7,490 | | Accrued manufacturing expenses | 9,569 | | | 15,216 | | Accrued royalties (1) | 8,852 | | | 12,022 | | Operating lease liabilities, current portion (2) | 8,480 | | | 6,791 | | Other accrued expenses | 7,841 | | | 10,534 | | Total | $ | 78,471 | | | $ | 96,342 | |
_______________________________ (1) Refer to Note 15, Commitments and Contingencies. (2) Refer to Note 12, Leases.
|
Schedule of accrued product returns and rebates |
Accrued Product Returns and Rebates | | | | | | | | | | | | | September 30, 2023 | | December 31, 2022 | | (unaudited) | | | Accrued product rebates | $ | 108,129 | | | $ | 106,657 | | Accrued product returns | 54,344 | | | 45,008 | | Total | $ | 162,473 | | | $ | 151,665 | |
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v3.23.3
Interest Expense (Tables)
|
9 Months Ended |
Sep. 30, 2023 |
Other Income and Expenses [Abstract] |
|
Schedule of interest expense |
The following details the composition of interest expense (dollars in thousands): | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended September 30, | | Nine Months Ended September 30, | | 2023 | | 2022 | | 2023 | | 2022 | | (unaudited) | | (unaudited) | Interest expense | $ | — | | | $ | (629) | | | $ | (1,321) | | | $ | (1,906) | | Noncash interest expense on nonrecourse liability related to sale of future royalties | — | | | (566) | | | (562) | | | (1,988) | | Noncash interest expense on debt | — | | | (529) | | | (532) | | | (1,582) | | Total | $ | — | | | $ | (1,724) | | | $ | (2,415) | | | $ | (5,476) | |
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v3.23.3
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v3.23.3
Summary of Significant Accounting Policies - Advertising Expense (Details) - USD ($) $ in Millions |
3 Months Ended |
9 Months Ended |
Sep. 30, 2023 |
Sep. 30, 2022 |
Sep. 30, 2023 |
Sep. 30, 2022 |
Accounting Policies [Abstract] |
|
|
|
|
Advertising costs |
$ 25.1
|
$ 52.0
|
$ 76.9
|
$ 112.8
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v3.23.3
Summary of Significant Accounting Policies - Recently Issued Accounting Pronouncements (Details) - USD ($) $ in Thousands |
Sep. 30, 2023 |
Jun. 30, 2023 |
Mar. 31, 2023 |
Dec. 31, 2022 |
Sep. 30, 2022 |
Jun. 30, 2022 |
Mar. 31, 2022 |
Jan. 01, 2022 |
Dec. 31, 2021 |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |
|
|
|
|
|
|
|
|
|
Stockholders' equity |
$ 912,191
|
$ 919,908
|
$ 912,150
|
$ 886,204
|
$ 852,798
|
$ 841,434
|
$ 828,446
|
|
$ 815,851
|
Accounting Standards Update 2020-06 |
|
|
|
|
|
|
|
|
|
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |
|
|
|
|
|
|
|
|
|
Long-term debt |
|
|
|
|
|
|
|
$ 20,600
|
|
Net deferred tax liabilities |
|
|
|
|
|
|
|
(5,000)
|
|
Cumulative effect of adoption of ASU 2020-06 |
|
|
|
|
|
|
|
|
|
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |
|
|
|
|
|
|
|
|
|
Stockholders' equity |
|
|
|
|
|
|
|
|
(15,600)
|
Retained Earnings |
|
|
|
|
|
|
|
|
|
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |
|
|
|
|
|
|
|
|
|
Stockholders' equity |
481,386
|
497,362
|
498,193
|
481,245
|
455,764
|
454,015
|
446,150
|
|
379,922
|
Retained Earnings | Cumulative effect of adoption of ASU 2020-06 |
|
|
|
|
|
|
|
|
|
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |
|
|
|
|
|
|
|
|
|
Stockholders' equity |
|
|
|
|
|
|
|
|
40,612
|
Retained Earnings | Cumulative effect of adoption of ASU 2020-06 | Accounting Standards Update 2020-06 |
|
|
|
|
|
|
|
|
|
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |
|
|
|
|
|
|
|
|
|
Stockholders' equity |
|
|
|
|
|
|
|
40,600
|
|
Additional Paid-in Capital |
|
|
|
|
|
|
|
|
|
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |
|
|
|
|
|
|
|
|
|
Stockholders' equity |
$ 431,956
|
$ 424,266
|
$ 416,232
|
$ 408,115
|
$ 401,026
|
$ 389,586
|
$ 383,016
|
|
434,337
|
Additional Paid-in Capital | Cumulative effect of adoption of ASU 2020-06 |
|
|
|
|
|
|
|
|
|
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |
|
|
|
|
|
|
|
|
|
Stockholders' equity |
|
|
|
|
|
|
|
|
$ (56,212)
|
Additional Paid-in Capital | Cumulative effect of adoption of ASU 2020-06 | Accounting Standards Update 2020-06 |
|
|
|
|
|
|
|
|
|
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |
|
|
|
|
|
|
|
|
|
Stockholders' equity |
|
|
|
|
|
|
|
$ (56,200)
|
|
X |
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v3.23.3
Disaggregated Revenues - Summary of Revenues and Product Sales (Details) - USD ($) $ in Thousands |
3 Months Ended |
9 Months Ended |
Sep. 30, 2023 |
Sep. 30, 2022 |
Sep. 30, 2023 |
Sep. 30, 2022 |
Disaggregation of Revenue [Line Items] |
|
|
|
|
Total revenues |
$ 153,880
|
$ 177,353
|
$ 443,207
|
$ 499,910
|
Net product sales |
|
|
|
|
Disaggregation of Revenue [Line Items] |
|
|
|
|
Total revenues |
$ 149,004
|
$ 172,724
|
$ 417,915
|
$ 485,647
|
Net product sales | Revenue from Contract with Customer Benchmark | Product Concentration Risk |
|
|
|
|
Disaggregation of Revenue [Line Items] |
|
|
|
|
Concentration risk percentage |
100.00%
|
100.00%
|
100.00%
|
100.00%
|
Qelbree |
|
|
|
|
Disaggregation of Revenue [Line Items] |
|
|
|
|
Total revenues |
$ 37,081
|
$ 18,326
|
$ 93,840
|
$ 37,708
|
Qelbree | Revenue from Contract with Customer Benchmark | Product Concentration Risk |
|
|
|
|
Disaggregation of Revenue [Line Items] |
|
|
|
|
Concentration risk percentage |
25.00%
|
11.00%
|
22.00%
|
8.00%
|
GOCOVRI |
|
|
|
|
Disaggregation of Revenue [Line Items] |
|
|
|
|
Total revenues |
$ 32,889
|
$ 27,878
|
$ 87,650
|
$ 75,179
|
GOCOVRI | Revenue from Contract with Customer Benchmark | Product Concentration Risk |
|
|
|
|
Disaggregation of Revenue [Line Items] |
|
|
|
|
Concentration risk percentage |
22.00%
|
16.00%
|
21.00%
|
15.00%
|
Oxtellar XR |
|
|
|
|
Disaggregation of Revenue [Line Items] |
|
|
|
|
Total revenues |
$ 29,644
|
$ 30,528
|
$ 82,359
|
$ 88,007
|
Oxtellar XR | Revenue from Contract with Customer Benchmark | Product Concentration Risk |
|
|
|
|
Disaggregation of Revenue [Line Items] |
|
|
|
|
Concentration risk percentage |
20.00%
|
18.00%
|
20.00%
|
18.00%
|
Trokendi XR |
|
|
|
|
Disaggregation of Revenue [Line Items] |
|
|
|
|
Total revenues |
$ 20,625
|
$ 69,599
|
$ 74,734
|
$ 204,033
|
Trokendi XR | Revenue from Contract with Customer Benchmark | Product Concentration Risk |
|
|
|
|
Disaggregation of Revenue [Line Items] |
|
|
|
|
Concentration risk percentage |
14.00%
|
40.00%
|
18.00%
|
42.00%
|
APOKYN |
|
|
|
|
Disaggregation of Revenue [Line Items] |
|
|
|
|
Total revenues |
$ 21,510
|
$ 18,261
|
$ 56,324
|
$ 57,156
|
APOKYN | Revenue from Contract with Customer Benchmark | Product Concentration Risk |
|
|
|
|
Disaggregation of Revenue [Line Items] |
|
|
|
|
Concentration risk percentage |
14.00%
|
10.00%
|
13.00%
|
12.00%
|
Other |
|
|
|
|
Disaggregation of Revenue [Line Items] |
|
|
|
|
Total revenues |
$ 7,255
|
$ 8,132
|
$ 23,008
|
$ 23,564
|
Other | Revenue from Contract with Customer Benchmark | Product Concentration Risk |
|
|
|
|
Disaggregation of Revenue [Line Items] |
|
|
|
|
Concentration risk percentage |
5.00%
|
5.00%
|
6.00%
|
5.00%
|
Royalty revenues |
|
|
|
|
Disaggregation of Revenue [Line Items] |
|
|
|
|
Total revenues |
$ 4,876
|
$ 4,629
|
$ 25,292
|
$ 14,263
|
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v3.23.3
Investments - Narrative (Details) - USD ($)
|
1 Months Ended |
3 Months Ended |
9 Months Ended |
Dec. 31, 2021 |
Apr. 30, 2020 |
Sep. 30, 2023 |
Sep. 30, 2022 |
Mar. 31, 2021 |
Sep. 30, 2023 |
Sep. 30, 2022 |
Investments, Debt and Equity Securities [Abstract] |
|
|
|
|
|
|
|
Impairment due to credit losses |
|
|
|
|
|
$ 0
|
|
Variable Interest Entity [Line Items] |
|
|
|
|
|
|
|
Research and development |
|
|
$ 22,655,000
|
$ 19,554,000
|
|
$ 68,246,000
|
$ 56,778,000
|
Cash distributions received |
$ 12,900,000
|
|
|
|
|
|
|
Variable Interest Entity, Not Primary Beneficiary |
|
|
|
|
|
|
|
Variable Interest Entity [Line Items] |
|
|
|
|
|
|
|
Research and development |
|
|
|
|
$ 15,000,000
|
|
|
Navitor Pharmaceuticals, Inc. | Variable Interest Entity, Not Primary Beneficiary |
|
|
|
|
|
|
|
Variable Interest Entity [Line Items] |
|
|
|
|
|
|
|
Agreement termination notice period |
|
30 days
|
|
|
|
|
|
Threshold for development costs payments |
|
$ 50,000,000
|
|
|
|
|
|
Investments |
|
$ 15,000,000
|
|
|
|
|
|
VIE, qualitative or quantitative information, ownership percentage |
|
13.00%
|
|
|
|
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v3.23.3
Fair Value of Financial Measurements - Carrying Value (Details) - USD ($) $ in Thousands |
Sep. 30, 2023 |
Dec. 31, 2022 |
Liabilities: |
|
|
Contingent consideration |
$ 53,654
|
$ 54,967
|
Recurring |
|
|
Other assets |
|
|
Marketable securities - restricted (SERP) |
512
|
496
|
Total assets at fair value |
225,826
|
555,726
|
Liabilities: |
|
|
Contingent consideration |
53,654
|
54,967
|
Total liabilities at fair value |
53,654
|
54,967
|
Recurring | Corporate and municipal debt securities |
|
|
Marketable securities |
|
|
Corporate and municipal debt securities |
105,204
|
368,214
|
Long-term marketable securities |
|
|
Corporate and municipal debt securities |
25,125
|
93,896
|
Recurring | Cash |
|
|
Cash and cash equivalents |
|
|
Cash and money market funds |
38,302
|
52,181
|
Recurring | Money market securities and funds |
|
|
Cash and cash equivalents |
|
|
Cash and money market funds |
56,683
|
40,939
|
Recurring | Level 1 |
|
|
Other assets |
|
|
Marketable securities - restricted (SERP) |
14
|
11
|
Total assets at fair value |
94,999
|
93,131
|
Liabilities: |
|
|
Contingent consideration |
0
|
0
|
Total liabilities at fair value |
0
|
0
|
Recurring | Level 1 | Corporate and municipal debt securities |
|
|
Marketable securities |
|
|
Corporate and municipal debt securities |
0
|
0
|
Long-term marketable securities |
|
|
Corporate and municipal debt securities |
0
|
0
|
Recurring | Level 1 | Cash |
|
|
Cash and cash equivalents |
|
|
Cash and money market funds |
38,302
|
52,181
|
Recurring | Level 1 | Money market securities and funds |
|
|
Cash and cash equivalents |
|
|
Cash and money market funds |
56,683
|
40,939
|
Recurring | Level 2 |
|
|
Other assets |
|
|
Marketable securities - restricted (SERP) |
498
|
485
|
Total assets at fair value |
130,827
|
462,595
|
Liabilities: |
|
|
Contingent consideration |
0
|
0
|
Total liabilities at fair value |
0
|
0
|
Recurring | Level 2 | Corporate and municipal debt securities |
|
|
Marketable securities |
|
|
Corporate and municipal debt securities |
105,204
|
368,214
|
Long-term marketable securities |
|
|
Corporate and municipal debt securities |
25,125
|
93,896
|
Recurring | Level 2 | Cash |
|
|
Cash and cash equivalents |
|
|
Cash and money market funds |
0
|
0
|
Recurring | Level 2 | Money market securities and funds |
|
|
Cash and cash equivalents |
|
|
Cash and money market funds |
0
|
0
|
Recurring | Level 3 |
|
|
Other assets |
|
|
Marketable securities - restricted (SERP) |
0
|
0
|
Total assets at fair value |
0
|
0
|
Liabilities: |
|
|
Contingent consideration |
53,654
|
54,967
|
Total liabilities at fair value |
53,654
|
54,967
|
Recurring | Level 3 | Corporate and municipal debt securities |
|
|
Marketable securities |
|
|
Corporate and municipal debt securities |
0
|
0
|
Long-term marketable securities |
|
|
Corporate and municipal debt securities |
0
|
0
|
Recurring | Level 3 | Cash |
|
|
Cash and cash equivalents |
|
|
Cash and money market funds |
0
|
0
|
Recurring | Level 3 | Money market securities and funds |
|
|
Cash and cash equivalents |
|
|
Cash and money market funds |
$ 0
|
$ 0
|
X |
- DefinitionFair value portion of probable future economic benefits obtained or controlled by an entity as a result of past transactions or events.
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v3.23.3
Contingent Consideration - Current and Long-Term Contingent Consideration (Details) - USD ($) $ in Thousands |
Sep. 30, 2023 |
Dec. 31, 2022 |
Business Combination and Asset Acquisition [Abstract] |
|
|
Contingent consideration, current portion |
$ 45,880
|
$ 21,120
|
Contingent consideration, long-term |
7,774
|
33,847
|
Total |
$ 53,654
|
$ 54,967
|
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v3.23.3
Contingent Consideration - Narrative (Details) $ / shares in Units, $ in Thousands |
|
3 Months Ended |
9 Months Ended |
Nov. 24, 2021
USD ($)
right
$ / shares
|
Sep. 30, 2023
USD ($)
|
Jun. 30, 2023
USD ($)
|
Mar. 31, 2023
USD ($)
|
Sep. 30, 2022
USD ($)
|
Jun. 30, 2022
USD ($)
|
Mar. 31, 2022
USD ($)
|
Sep. 30, 2023
USD ($)
|
Sep. 30, 2022
USD ($)
|
Business Acquisition [Line Items] |
|
|
|
|
|
|
|
|
|
Change in fair value recognized in earnings |
|
$ (456)
|
$ 790
|
$ (1,647)
|
$ 486
|
$ 743
|
$ 665
|
|
|
Milestone payments |
|
|
|
|
|
|
25,000
|
|
|
Payment for contingent consideration liability, financing activities |
|
|
|
|
|
22,900
|
|
$ 0
|
$ 22,900
|
Payment for contingent consideration liability, operating activities |
|
|
|
|
|
2,100
|
|
|
|
USWM Acquisition |
|
|
|
|
|
|
|
|
|
Business Acquisition [Line Items] |
|
|
|
|
|
|
|
|
|
Additional cash payments upon milestone achievements maximum |
|
85,000
|
|
|
|
|
|
85,000
|
|
Change in fair value recognized in earnings |
|
660
|
660
|
(1,710)
|
350
|
350
|
1,720
|
(400)
|
2,400
|
Milestone payments |
|
|
|
|
|
|
25,000
|
|
|
USWM Acquisition | SPN-30 Regulatory and Commercial Activities |
|
|
|
|
|
|
|
|
|
Business Acquisition [Line Items] |
|
|
|
|
|
|
|
|
|
Additional cash payments upon milestone achievements maximum |
|
55,000
|
|
|
|
|
|
55,000
|
|
USWM Acquisition | SPN-830 NDA Approval Milestone |
|
|
|
|
|
|
|
|
|
Business Acquisition [Line Items] |
|
|
|
|
|
|
|
|
|
Additional cash payments upon milestone achievements maximum |
|
25,000
|
|
|
|
|
|
25,000
|
|
USWM Acquisition | APOKYN and SPN-830 |
|
|
|
|
|
|
|
|
|
Business Acquisition [Line Items] |
|
|
|
|
|
|
|
|
|
Additional cash payments upon milestone achievements maximum |
|
30,000
|
|
|
|
|
|
30,000
|
|
USWM Acquisition | Subsequent Commercial Product Launch |
|
|
|
|
|
|
|
|
|
Business Acquisition [Line Items] |
|
|
|
|
|
|
|
|
|
Additional cash payments upon milestone achievements maximum |
|
30,000
|
|
|
|
|
|
30,000
|
|
Adamas Acquisition |
|
|
|
|
|
|
|
|
|
Business Acquisition [Line Items] |
|
|
|
|
|
|
|
|
|
Additional cash payments upon milestone achievements maximum |
$ 50,900
|
|
|
|
|
|
|
|
|
Contingents value rights | right |
2
|
|
|
|
|
|
|
|
|
Contingent consideration arrangements, value (in dollars per share) | $ / shares |
$ 0.50
|
|
|
|
|
|
|
|
|
Additional cash payments upon milestone achievements minimum |
$ 0
|
|
|
|
|
|
|
|
|
Change in fair value recognized in earnings |
|
$ (1,116)
|
$ 130
|
$ 63
|
$ 136
|
$ 393
|
(1,055)
|
$ (900)
|
$ (500)
|
Milestone payments |
|
|
|
|
|
|
$ 0
|
|
|
Adamas Acquisition | The Milestones |
|
|
|
|
|
|
|
|
|
Business Acquisition [Line Items] |
|
|
|
|
|
|
|
|
|
Contingent consideration arrangements, excess acquisition date fair value |
$ 225,000
|
|
|
|
|
|
|
|
|
Contingent consideration arrangements, excess acquisition date fair value, term |
12 months
|
|
|
|
|
|
|
|
|
Adamas Acquisition | Milestone 2024 |
|
|
|
|
|
|
|
|
|
Business Acquisition [Line Items] |
|
|
|
|
|
|
|
|
|
Contingent consideration arrangements, excess acquisition date fair value |
$ 150,000
|
|
|
|
|
|
|
|
|
Contingent consideration arrangements, excess acquisition date fair value, term |
12 months
|
|
|
|
|
|
|
|
|
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v3.23.3
Contingent Consideration - Reconciliation of the Beginning and Ending Balances Related to the Contingent Consideration (Details) - USD ($) $ in Thousands |
3 Months Ended |
9 Months Ended |
Sep. 30, 2023 |
Jun. 30, 2023 |
Mar. 31, 2023 |
Sep. 30, 2022 |
Jun. 30, 2022 |
Mar. 31, 2022 |
Sep. 30, 2023 |
Sep. 30, 2022 |
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Roll Forward] |
|
|
|
|
|
|
|
|
Balance at December 31, 2022 |
$ 54,110
|
$ 53,320
|
$ 54,967
|
$ 56,885
|
$ 56,142
|
$ 80,477
|
$ 54,967
|
$ 80,477
|
Milestone payments |
|
|
|
|
|
(25,000)
|
|
|
Change in fair value recognized in earnings |
(456)
|
790
|
(1,647)
|
486
|
743
|
665
|
|
|
Balance at September 30, 2023 (unaudited) |
53,654
|
54,110
|
53,320
|
57,371
|
56,885
|
56,142
|
53,654
|
57,371
|
USWM Acquisition |
|
|
|
|
|
|
|
|
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Roll Forward] |
|
|
|
|
|
|
|
|
Balance at December 31, 2022 |
45,220
|
44,560
|
46,270
|
47,240
|
46,890
|
70,170
|
46,270
|
70,170
|
Milestone payments |
|
|
|
|
|
(25,000)
|
|
|
Change in fair value recognized in earnings |
660
|
660
|
(1,710)
|
350
|
350
|
1,720
|
(400)
|
2,400
|
Balance at September 30, 2023 (unaudited) |
45,880
|
45,220
|
44,560
|
47,590
|
47,240
|
46,890
|
45,880
|
47,590
|
Adamas Acquisition |
|
|
|
|
|
|
|
|
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Roll Forward] |
|
|
|
|
|
|
|
|
Balance at December 31, 2022 |
8,890
|
8,760
|
8,697
|
9,645
|
9,252
|
10,307
|
8,697
|
10,307
|
Milestone payments |
|
|
|
|
|
0
|
|
|
Change in fair value recognized in earnings |
(1,116)
|
130
|
63
|
136
|
393
|
(1,055)
|
(900)
|
(500)
|
Balance at September 30, 2023 (unaudited) |
$ 7,774
|
$ 8,890
|
$ 8,760
|
$ 9,781
|
$ 9,645
|
$ 9,252
|
$ 7,774
|
$ 9,781
|
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v3.23.3
Intangible Assets, Net - Intangible Assets Gross Carrying Amount and Related Accumulated Amortization (Details) - USD ($) $ in Thousands |
3 Months Ended |
9 Months Ended |
|
Sep. 30, 2023 |
Sep. 30, 2022 |
Sep. 30, 2023 |
Sep. 30, 2022 |
Dec. 31, 2022 |
Finite-Lived Intangible Assets [Line Items] |
|
|
|
|
|
Remaining Weighted Average Life (Years) |
7 years
|
|
7 years
|
|
|
Accumulated Amortization |
$ (208,173)
|
|
$ (208,173)
|
|
$ (146,857)
|
Amortization of intangible assets |
21,242
|
$ 20,644
|
61,316
|
$ 61,932
|
|
Total intangible assets, carrying amount, gross |
849,320
|
|
849,320
|
|
849,320
|
Intangible assets, net |
641,147
|
|
641,147
|
|
702,463
|
Amortization of intangible assets |
21,242
|
20,644
|
61,316
|
$ 61,932
|
|
Maximum |
|
|
|
|
|
Finite-Lived Intangible Assets [Line Items] |
|
|
|
|
|
Amortization of intangible assets |
|
20,600
|
|
|
|
Amortization of intangible assets |
|
$ 20,600
|
|
|
|
Acquired in-process research and development |
|
|
|
|
|
Indefinite-lived Intangible Assets [Line Items] |
|
|
|
|
|
Acquired in-process research and development |
$ 124,000
|
|
$ 124,000
|
|
124,000
|
Acquired developed technology and product rights |
|
|
|
|
|
Finite-Lived Intangible Assets [Line Items] |
|
|
|
|
|
Remaining Weighted Average Life (Years) |
7 years 29 days
|
|
7 years 29 days
|
|
|
Carrying Amount, Gross |
$ 681,500
|
|
$ 681,500
|
|
681,500
|
Accumulated Amortization |
(171,191)
|
|
(171,191)
|
|
(113,061)
|
Carrying Amount, Net |
$ 510,309
|
|
$ 510,309
|
|
568,439
|
Capitalized patent defense costs |
|
|
|
|
|
Finite-Lived Intangible Assets [Line Items] |
|
|
|
|
|
Remaining Weighted Average Life (Years) |
11 months 1 day
|
|
11 months 1 day
|
|
|
Carrying Amount, Gross |
$ 43,820
|
|
$ 43,820
|
|
43,820
|
Accumulated Amortization |
(36,982)
|
|
(36,982)
|
|
(33,796)
|
Carrying Amount, Net |
$ 6,838
|
|
$ 6,838
|
|
$ 10,024
|
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v3.23.3
Debt - Narrative (Details) - USD ($)
|
|
|
1 Months Ended |
3 Months Ended |
6 Months Ended |
9 Months Ended |
|
Apr. 01, 2023 |
Mar. 30, 2023 |
Mar. 31, 2018 |
Sep. 30, 2023 |
Sep. 30, 2022 |
Jun. 30, 2023 |
Sep. 30, 2023 |
Sep. 30, 2022 |
Feb. 08, 2023 |
Debt Instrument [Line Items] |
|
|
|
|
|
|
|
|
|
Cash paid for interest on debt |
|
|
|
|
|
|
$ 1,946,000
|
$ 2,516,000
|
|
Strike price of the warrant transactions (in dollars per share) |
|
|
|
$ 80.91
|
|
|
$ 80.91
|
|
|
Interest expense |
|
|
|
$ 0
|
$ 629,000
|
|
$ 1,321,000
|
$ 1,906,000
|
|
Convertible Debt |
|
|
|
|
|
|
|
|
|
Debt Instrument [Line Items] |
|
|
|
|
|
|
|
|
|
Interest rate |
|
|
|
0.625%
|
|
|
0.625%
|
|
|
Repayments of debt |
|
$ 403,800,000
|
|
|
|
|
|
|
|
Extinguishment of debt |
$ 402,500,000
|
|
|
|
|
|
|
|
|
Cash paid for interest on debt |
$ 1,300,000
|
|
|
|
|
|
|
|
|
Convertible note hedge options issued (in shares) |
|
|
402,500
|
|
|
|
|
|
|
Warrants issued (in shares) |
|
|
|
6,783,939
|
|
|
6,783,939
|
|
|
Number of shares per warrant entitled to holder (in shares) |
|
|
|
|
|
|
1
|
|
|
Revolving Credit Facility | Line of Credit |
|
|
|
|
|
|
|
|
|
Debt Instrument [Line Items] |
|
|
|
|
|
|
|
|
|
Repayments of debt |
|
|
|
|
|
$ 93,000,000
|
|
|
|
Line of credit facility, maximum borrowing capacity |
|
|
|
|
|
|
|
|
$ 150,000,000
|
Proceeds from issuance of debt |
|
$ 93,000,000
|
|
|
|
|
|
|
|
Interest expense |
|
|
|
|
|
$ 700,000
|
|
|
|
Short-term debt |
|
|
|
$ 0
|
|
|
$ 0
|
|
|
X |
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v3.23.3
Share-Based Payments - Share-based Compensation Expense (Details) - USD ($) $ in Thousands |
3 Months Ended |
9 Months Ended |
Sep. 30, 2023 |
Sep. 30, 2022 |
Sep. 30, 2023 |
Sep. 30, 2022 |
Share-based payments |
|
|
|
|
Total |
$ 7,920
|
$ 4,985
|
$ 20,314
|
$ 13,307
|
Research and development |
|
|
|
|
Share-based payments |
|
|
|
|
Total |
1,254
|
825
|
3,458
|
2,284
|
Selling, general and administrative |
|
|
|
|
Share-based payments |
|
|
|
|
Total |
$ 6,666
|
$ 4,160
|
$ 16,856
|
$ 11,023
|
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Share-Based Payments - SAR Activity (Details) - Stock option and Stock Appreciation Rights - $ / shares
|
9 Months Ended |
12 Months Ended |
Sep. 30, 2023 |
Dec. 31, 2022 |
Number of Options |
|
|
Outstanding at the beginning of the period (in shares) |
5,797,569
|
|
Granted (in shares) |
1,148,143
|
|
Exercised (in shares) |
(228,628)
|
|
Forfeited (in shares) |
(91,986)
|
|
Outstanding at the end of the period (in shares) |
6,625,098
|
5,797,569
|
Vested and expected to vest (in shares) |
6,625,098
|
5,797,569
|
Exercisable (in shares) |
4,116,000
|
3,541,395
|
Weighted Average Exercise Price |
|
|
Outstanding at the beginning of the period (in dollars per share) |
$ 26.99
|
|
Granted (in dollars per share) |
38.28
|
|
Exercised (in dollars per share) |
17.50
|
|
Forfeited (in dollars per share) |
33.24
|
|
Outstanding at the end of the period (in dollars per share) |
29.17
|
$ 26.99
|
Vested and expected to vest (in dollars per share) |
29.17
|
26.99
|
Exercisable (in dollars per share) |
$ 26.44
|
$ 25.08
|
Weighted Average Remaining Contractual Term (in years) |
|
|
Outstanding at the end of the period |
6 years 1 month 20 days
|
6 years 1 month 9 days
|
Vested and expected to vest |
6 years 1 month 20 days
|
6 years 1 month 9 days
|
Exercisable |
4 years 7 months 24 days
|
4 years 8 months 4 days
|
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|
9 Months Ended |
Sep. 30, 2023
$ / shares
shares
|
Number of RSUs |
|
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131,960
|
Granted (in shares) | shares |
227,980
|
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(47,049)
|
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(6,375)
|
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306,516
|
Weighted Average Grant Date Fair Value per Share |
|
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$ 32.17
|
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38.60
|
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32.18
|
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34.63
|
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$ 36.90
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v3.23.3
Share-Based Payments - Performance Stock Units (Details)
|
9 Months Ended |
Sep. 30, 2023
$ / shares
shares
|
Total PSUs |
|
Number of PSUs |
|
Nonvested, beginning balance (in shares) | shares |
201,750
|
Granted (in shares) | shares |
205,000
|
Vested (in shares) | shares |
(102,520)
|
Forfeited (in shares) | shares |
(3,000)
|
Nonvested, ending balance (in shares) | shares |
301,230
|
Weighted Average Grant Date Fair Value per Share |
|
Nonvested, beginning balance (in dollars per share) | $ / shares |
$ 29.03
|
Granted (in dollars per share) | $ / shares |
34.00
|
Vested (in dollars per share) | $ / shares |
31.04
|
Forfeited (in dollars per share) | $ / shares |
28.93
|
Nonvested, ending balance (in dollars per share) | $ / shares |
$ 31.73
|
Performance-Based Units |
|
Number of PSUs |
|
Nonvested, beginning balance (in shares) | shares |
181,750
|
Granted (in shares) | shares |
205,000
|
Vested (in shares) | shares |
(102,520)
|
Forfeited (in shares) | shares |
(3,000)
|
Nonvested, ending balance (in shares) | shares |
281,230
|
Weighted Average Grant Date Fair Value per Share |
|
Nonvested, beginning balance (in dollars per share) | $ / shares |
$ 29.07
|
Granted (in dollars per share) | $ / shares |
34.00
|
Vested (in dollars per share) | $ / shares |
31.04
|
Forfeited (in dollars per share) | $ / shares |
28.93
|
Nonvested, ending balance (in dollars per share) | $ / shares |
$ 31.95
|
Market-Based Units |
|
Number of PSUs |
|
Nonvested, beginning balance (in shares) | shares |
20,000
|
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0
|
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0
|
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0
|
Nonvested, ending balance (in shares) | shares |
20,000
|
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|
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$ 28.63
|
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0
|
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|
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|
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v3.23.3
Earnings (Loss) per Share (Details) - USD ($) $ / shares in Units, $ in Thousands |
3 Months Ended |
9 Months Ended |
Sep. 30, 2023 |
Jun. 30, 2023 |
Mar. 31, 2023 |
Sep. 30, 2022 |
Jun. 30, 2022 |
Mar. 31, 2022 |
Sep. 30, 2023 |
Sep. 30, 2022 |
Income per share |
|
|
|
|
|
|
|
|
Strike price of the warrant transactions (in dollars per share) |
$ 80.91
|
|
|
|
|
|
$ 80.91
|
|
Numerator: |
|
|
|
|
|
|
|
|
Net earnings (loss) |
$ (15,976)
|
$ (831)
|
$ 16,948
|
$ 1,749
|
$ 7,865
|
$ 25,616
|
$ 141
|
$ 35,230
|
After-tax interest expense for 2023 Notes |
0
|
|
|
0
|
|
|
0
|
2,664
|
Numerator for dilutive earnings (loss) per share |
$ (15,976)
|
|
|
$ 1,749
|
|
|
$ 141
|
$ 37,894
|
Denominator: |
|
|
|
|
|
|
|
|
Weighted average shares outstanding, basic (in shares) |
54,608,963
|
|
|
53,789,674
|
|
|
54,498,687
|
53,517,838
|
Effect of dilutive securities: |
|
|
|
|
|
|
|
|
Stock options, RSU and SAR (in shares) |
0
|
|
|
1,245,164
|
|
|
1,076,235
|
1,241,347
|
Convertible notes |
0
|
|
|
0
|
|
|
0
|
6,783,936
|
Weighted average shares outstanding, diluted (in shares) |
54,608,963
|
|
|
55,034,838
|
|
|
55,574,922
|
61,543,121
|
Earnings per share, basic (in dollars per share) |
$ (0.29)
|
|
|
$ 0.03
|
|
|
$ 0.00
|
$ 0.66
|
Earnings per share, diluted (in dollars per share) |
(0.29)
|
|
|
$ 0.03
|
|
|
0.00
|
$ 0.62
|
Convertible Debt |
|
|
|
|
|
|
|
|
Income per share |
|
|
|
|
|
|
|
|
Conversion price, per share of common stock (in dollars per share) |
$ 59.33
|
|
|
|
|
|
$ 59.33
|
|
2023 Notes |
|
|
|
|
|
|
|
|
Income per share |
|
|
|
|
|
|
|
|
Common stock equivalents excluded in the calculation of diluted income per share (in shares) |
0
|
|
|
6,783,936
|
|
|
2,261,312
|
0
|
Stock options, RSUs, PSUs |
|
|
|
|
|
|
|
|
Income per share |
|
|
|
|
|
|
|
|
Common stock equivalents excluded in the calculation of diluted income per share (in shares) |
411,506
|
|
|
792,904
|
|
|
486,080
|
470,822
|
X |
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v3.23.3
v3.23.3
Leases (Details) - USD ($) $ in Thousands |
Sep. 30, 2023 |
Dec. 31, 2022 |
Assets |
|
|
Operating lease assets |
$ 29,456
|
$ 28,904
|
Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible List] |
Other assets
|
Other assets
|
Liabilities |
|
|
Operating lease liabilities, current portion |
$ 8,480
|
$ 6,791
|
Operating Lease, Liability, Current, Statement of Financial Position [Extensible List] |
Accounts payable and accrued liabilities
|
Accounts payable and accrued liabilities
|
Operating lease liabilities, long-term |
$ 33,841
|
$ 35,998
|
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible List] |
Operating lease liabilities, long-term
|
Operating lease liabilities, long-term
|
Total lease liabilities |
$ 42,321
|
$ 42,789
|
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Composition of Other Balance Sheet Items - Inventories (Details) - USD ($) $ in Thousands |
Sep. 30, 2023 |
Dec. 31, 2022 |
Organization, Consolidation and Presentation of Financial Statements [Abstract] |
|
|
Raw materials |
$ 21,556
|
$ 24,820
|
Work in process |
26,966
|
31,710
|
Finished goods |
34,958
|
35,011
|
Total inventories |
$ 83,480
|
$ 91,541
|
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v3.23.3
Composition of Other Balance Sheet Items - Property and Equipment (Details) - USD ($) $ in Thousands |
3 Months Ended |
9 Months Ended |
|
Sep. 30, 2023 |
Sep. 30, 2022 |
Sep. 30, 2023 |
Sep. 30, 2022 |
Dec. 31, 2022 |
Property and equipment |
|
|
|
|
|
Property and equipment, gross |
$ 28,604
|
|
$ 28,604
|
|
$ 28,222
|
Less accumulated depreciation and amortization |
(14,916)
|
|
(14,916)
|
|
(13,049)
|
Property and equipment, net |
13,688
|
|
13,688
|
|
15,173
|
Depreciation and amortization expense |
600
|
$ 800
|
1,900
|
$ 2,200
|
|
Lab equipment and furniture |
|
|
|
|
|
Property and equipment |
|
|
|
|
|
Property and equipment, gross |
12,620
|
|
12,620
|
|
12,127
|
Leasehold improvements |
|
|
|
|
|
Property and equipment |
|
|
|
|
|
Property and equipment, gross |
14,023
|
|
14,023
|
|
14,023
|
Software |
|
|
|
|
|
Property and equipment |
|
|
|
|
|
Property and equipment, gross |
883
|
|
883
|
|
883
|
Computer equipment |
|
|
|
|
|
Property and equipment |
|
|
|
|
|
Property and equipment, gross |
1,078
|
|
1,078
|
|
983
|
Construction-in-progress |
|
|
|
|
|
Property and equipment |
|
|
|
|
|
Property and equipment, gross |
$ 0
|
|
$ 0
|
|
$ 206
|
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v3.23.3
Composition of Other Balance Sheet Items - Accrued Payable and Accrued Liabilities (Details) - USD ($) $ in Thousands |
Sep. 30, 2023 |
Dec. 31, 2022 |
Organization, Consolidation and Presentation of Financial Statements [Abstract] |
|
|
Accounts payable |
$ 3,389
|
$ 10,543
|
Accrued compensation, benefits, & related accruals |
19,025
|
16,963
|
Accrued sales & marketing |
11,656
|
16,783
|
Accrued R&D expenses |
9,659
|
7,490
|
Accrued manufacturing expenses |
9,569
|
15,216
|
Accrued royalties |
8,852
|
12,022
|
Operating lease liabilities, current portion |
8,480
|
6,791
|
Other accrued expenses |
7,841
|
10,534
|
Total |
$ 78,471
|
$ 96,342
|
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3 Months Ended |
9 Months Ended |
Sep. 30, 2023 |
Sep. 30, 2022 |
Sep. 30, 2023 |
Sep. 30, 2022 |
Other Income and Expenses [Abstract] |
|
|
|
|
Interest expense |
$ 0
|
$ (629)
|
$ (1,321)
|
$ (1,906)
|
Noncash interest expense on nonrecourse liability related to sale of future royalties |
0
|
(566)
|
(562)
|
(1,988)
|
Noncash interest expense on debt |
0
|
(529)
|
(532)
|
(1,582)
|
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|
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|
$ (2,415)
|
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