Filed
Pursuant to Rule 424(b)(3)
Registration
No. 333-269442
Prospectus
Supplement No. 3 Dated May 19, 2023
(To
Prospectus Dated April 26, 2023)
11,015,500
Shares of Common Stock
Warrants
to Purchase up to 11,015,500 Shares of Common Stock
11,015,500
Shares of Common Stock underlying the Warrants
This
Prospectus Supplement No. 3 (this “Prospectus Supplement”) supplements the prospectus of ZyVersa Therapeutics, Inc.
(the “Company”, “we”, “us”, or “our”) dated April 26, 2023
(as supplemented to date, the “Prospectus”) with the following attached
document which we filed with the Securities and Exchange Commission:
| A. | Our
Current Report on Form 8-K filed with the Securities and Exchange Commission on May 19, 2023. |
This
Prospectus Supplement should be read in conjunction with the Prospectus, which is required to be delivered with this Prospectus Supplement.
This Prospectus Supplement updates, amends and supplements the information included in the Prospectus.
If there is any inconsistency between the information in the Prospectus and this Prospectus Supplement, you should rely on the information
in this Prospectus Supplement.
This
Prospectus Supplement is not complete without, and may not be delivered or utilized except
in connection with, the Prospectus, including any amendments or supplements to it.
Investing
in our securities involves a high degree of risk. See “Risk Factors” beginning on page 7 of the Prospectus.
You
should rely only on the information contained in the Prospectus, as supplemented or amended by this Prospectus Supplement and any other
prospectus supplement or amendment thereto. We have not authorized anyone to provide you with different information.
Neither
the Securities and Exchange Commission nor any state securities commission has approved or disapproved of these securities or determined
if this prospectus is truthful or complete. Any representation to the contrary is a criminal offense.
The
date of this Prospectus Supplement No. 3 is May 19, 2023
INDEX
TO FILINGS
ANNEX
A
UNITED
STATES
SECURITIES
AND EXCHANGE COMMISSION
Washington,
DC 20549
FORM
8-K
CURRENT
REPORT
Pursuant
to Section 13 or 15(d) of the Securities Exchange Act of 1934
Date
of Report (Date of earliest event reported): May 17, 2023
ZYVERSA
THERAPEUTICS, INC.
(Exact
name of registrant as specified in its charter)
Delaware |
|
001-41184 |
|
86-2685744 |
(State
or other jurisdiction |
|
(Commission |
|
(I.R.S.
Employer |
of
incorporation) |
|
File
Number) |
|
Identification
No.) |
2200
N. Commerce Parkway, Suite 208
Weston,
Florida, 33326
(Address
of principal executive offices) (Zip Code)
(754)
231-1688
(Registrant’s
telephone number, including area code)
Check
the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under
any of the following provisions (see General Instruction A.2. below):
☐ |
Written
communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) |
|
|
☐ |
Soliciting
material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) |
|
|
☐ |
Pre-commencement
communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) |
|
|
☐ |
Pre-commencement
communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) |
Securities
registered pursuant to Section 12(b) of the Act:
Title
of Each Class |
|
Trading
Symbols |
|
Name
of each exchange on which registered |
Common
Stock, par value $0.0001 per share |
|
ZVSA |
|
The
Nasdaq Global Market |
Indicate
by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405
of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
Emerging
growth company ☒
If
an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying
with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐
Item
5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of
Certain Officers.
On
May 17, 2023, Katrin Rupalla, Ph.D., notified the Board of Directors (the “Board”) of ZyVersa Therapeutics, Inc. (the
“Company”) that she was resigning from the Board effective May 18, 2023. Dr. Rupalla did not resign from the Board
due to any disagreement with the Company on any matter relating to the Company’s operations, policies or practices.
On
May 17, 2023, Daniel J. O’Connor, notified the Board of the Company that he was resigning from the Board effective May
18, 2023. Mr. O’Connor did not resign from the Board due to any disagreement with the Company on any matter relating to the
Company’s operations, policies or practices.
Item 9.01. Financial
Statements and Exhibits.
(d) Exhibits:
SIGNATURES
Pursuant
to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by
the undersigned hereunto duly authorized.
|
ZyVersa
Therapeutics, Inc. |
|
|
|
May
19, 2023 |
By: |
/s/
Stephen C. Glover |
|
Name: |
Stephen
C. Glover |
|
Title: |
Chief
Executive Officer |
Exhibit 99.1
ZyVersa
Therapeutics Announces Changes to ZyVersa Board of Directors
Weston,
FL (May 19, 2023) – ZyVersa Therapeutics, Inc. (Nasdaq: ZVSA, or “ZyVersa”), a clinical stage specialty biopharmaceutical
company developing first-in-class drugs for the treatment of renal and inflammatory diseases with high unmet medical needs, announces
that two members of the Board of Directors have stepped down due to obligations associated with recent executive opportunities: Katrin
Rupalla, PhD and Daniel O’Connor. Dr. Rupalla resigned from ZyVersa’s Board of Directors to pursue an opportunity that precludes
her ability to serve on any board of directors. Mr. O’Connor, the former CEO of Larkspur which merged with ZyVersa in December
of 2022, has recently taken on the CEO role at Ambrx Biopharma and has resigned to focus on growth of his new company.
“On
behalf of the Board of Directors and the team at ZyVersa, I would like to thank Dr. Rupalla and Mr. O’Connor for their impactful
leadership during their tenure as Board members at ZyVersa,” said Stephen C. Glover, Co-founder, Chairman, Chief Executive Officer,
and President of ZyVersa. “As biopharmaceutical leaders with impeccable credentials and a proven track record of success, their
knowledge and perspectives have been invaluable as we progress development of our company and our lead renal and anti-inflammatory assets.”
About
ZyVersa Therapeutics, Inc.
ZyVersa
(Nasdaq: ZVSA) is a clinical stage specialty biopharmaceutical company leveraging advanced, proprietary technologies to develop first-in-class
drugs for patients with renal and inflammatory diseases who have significant unmet medical needs. The Company is currently advancing
a therapeutic development pipeline with multiple programs built around its two proprietary technologies – Cholesterol Efflux Mediator™
VAR 200 developed to ameliorate renal lipid accumulation that damages the kidneys’ filtration system in patients with glomerular
kidney diseases, and Inflammasome ASC Inhibitor IC 100, targeting damaging inflammation associated with numerous CNS and other inflammatory
diseases. For more information, please visit www.zyversa.com.
Cautionary
Statement Regarding Forward-Looking Statements
Certain
statements contained in this press release regarding matters that are not historical facts, are forward-looking statements within the
meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and the Private Securities Litigation Reform Act of 1995.
These include statements regarding management’s intentions, plans, beliefs, expectations, or forecasts for the future, and, therefore,
you are cautioned not to place undue reliance on them. No forward-looking statement can be guaranteed, and actual results may differ
materially from those projected. ZyVersa Therapeutics, Inc (“ZyVersa”) uses words such as “anticipates,” “believes,”
“plans,” “expects,” “projects,” “future,” “intends,” “may,” “will,”
“should,” “could,” “estimates,” “predicts,” “potential,” “continue,”
“guidance,” and similar expressions to identify these forward-looking statements that are intended to be covered by the safe-harbor
provisions. Such forward-looking statements are based on ZyVersa’s expectations and involve risks and uncertainties; consequently,
actual results may differ materially from those expressed or implied in the statements due to a number of factors, including ZyVersa’s
plans to develop and commercialize its product candidates, the timing of initiation of ZyVersa’s planned preclinical and clinical
trials; the timing of the availability of data from ZyVersa’s preclinical and clinical trials; the timing of any planned investigational
new drug application or new drug application; ZyVersa’s plans to research, develop, and commercialize its current and future product
candidates; the clinical utility, potential benefits and market acceptance of ZyVersa’s product candidates; ZyVersa’s commercialization,
marketing and manufacturing capabilities and strategy; ZyVersa’s ability to protect its intellectual property position; and ZyVersa’s
estimates regarding future revenue, expenses, capital requirements and need for additional financing.
New
factors emerge from time-to-time, and it is not possible for ZyVersa to predict all such factors, nor can ZyVersa assess the impact of
each such factor on the business or the extent to which any factor, or combination of factors, may cause actual results to differ materially
from those contained in any forward-looking statements. Forward-looking statements included in this press release are based on information
available to ZyVersa as of the date of this press release. ZyVersa disclaims any obligation to update such forward-looking statements
to reflect events or circumstances after the date of this press release, except as required by applicable law.
This
press release does not constitute an offer to sell, or the solicitation of an offer to buy, any securities.
Corporate
and IR Contact:
Karen
Cashmere
Chief
Commercial Officer
kcashmere@zyversa.com
786-251-9641
Media
Contacts
Tiberend
Strategic Advisors, Inc.
Casey
McDonald
cmcdonald@tiberend.com
646-577-8520
Dave
Schemelia
dschemelia@tiberend.com
609-468-9325
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