Bioasis Announces Allowance of Japanese Patent Application in Japan Relating to xB³™ Fusion Protein Comprising Iduronate-2-sulfatase
10 August 2021 - 7:00AM
BIOASIS TECHNOLOGIES INC. (TSXV:BTI; OTCQB:BIOAF),
(the “Company” or “Bioasis”), a pre-clinical, research-stage
biopharmaceutical company developing its proprietary xB3™ platform
technology to enhance the delivery of biologics across the
blood-brain barrier (“BBB”) for the treatment of central nervous
system (“CNS”) disorders in areas of high unmet medical need,
including brain cancers and neurodegenerative diseases, today
announced that the Japanese Patent Office (“JPO”) issued Japanese
Patent No. 2019-189551 Notice of Allowance for the Company’s
xB3-IDS fusion proteins.
The patent relates to fusion proteins between Bioasis’
xB3™ and Iduronate-2-sulfatase (IDS), and compositions and
methods related to the use thereof. The issued claims of this
patent cover the compositions for xB3™-IDS fusion protein and
treatment of lysosomal storage disease with or at risk of
developing central nervous system involvement, including Hunter
Syndrome (MPS II). This patent follows the June 18, 2020,
Australian patent application No. 2015219339 granted by the
Australian patent office also relating to the
iduronate-2-sulfatase, or IDS,
polypeptide. “We are excited about
the acceptance of this patent by the Japanese Patent Office. It
represents a major milestone for our intellectual property
protection around our core assets for the delivery in the Lysosomal
Storage Disease area in the important Asian market, particularly
the Japanese market. In addition to the already granted patents
worldwide, this further strengthens and reinforces our standing
around our xB3™ platform technology, particularly in the
Lysosomal Storage Disease area,” said Dr. Deborah Rathjen,
Executive Chair of the Board of Bioasis.
On behalf of the Board of Directors of Bioasis
Technologies Inc.Deborah Rathjen, Ph.D., Executive Chair
of the Board
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About BioasisBioasis Technologies Inc. is a
biopharmaceutical company developing the xB3™ platform, a
proprietary technology for the delivery of therapeutics across the
blood brain barrier and the treatment of CNS disorders in areas of
high unmet medical need, including brain cancers and
neurodegenerative diseases. The delivery of therapeutics across the
blood brain barrier represents the final frontier in treating
neurological disorders. The in-house development programs at
Bioasis are designed to develop symptomatic and disease-modifying
treatments for brain-related diseases and disorders. For more
information about the Company, please visit www.bioasis.us.
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statements within the meaning of the Private Securities Litigation
Reform Act of 1995 or forward-looking information under applicable
Canadian securities legislation that may not be based on historical
fact along with other statements containing the words “believe,”
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uncertainties and other factors that may cause our actual results,
events or developments, or industry results, to be materially
different from any future results, events or developments express
or implied by such forward-looking statements or information. Such
factors include, among others, our stage of development, lack of
any product revenues, additional capital requirements, risk
associated with the completion of clinical trials and obtaining
regulatory approval to market our products, the ability to protect
our intellectual property, dependence on collaborative partners and
the prospects for negotiating additional corporate collaborations
or licensing arrangements and their timing. Specifically, certain
risks and uncertainties that could cause such actual events or
results expressed or implied by such forward-looking statements and
information to differ materially from any future events or results
expressed or implied by such statements and information include,
but are not limited to, the risks and uncertainties that: products
that we develop may not succeed in preclinical or clinical trials,
or future products in our targeted corporate objectives; our future
operating results are uncertain and likely to fluctuate; we may not
be able to raise additional capital; we may not be successful in
establishing additional corporate collaborations or licensing
arrangements; we may not be able to establish marketing and the
costs of launching our products may be greater than anticipated; we
have no experience in commercial manufacturing; we may face unknown
risks related to intellectual property matters; we face increased
competition from pharmaceutical and biotechnology companies; and
other factors as described in detail in our filings with the
Canadian securities regulatory authorities at www.sedar.com. Given
these risks and uncertainties, you are cautioned not to place undue
reliance on such forward-looking statements and information, which
are qualified in their entirety by this cautionary statement. All
forward-looking statements and information made herein are based on
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or update such forward-looking statements and information to
reflect subsequent events or circumstances, except as required by
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Contacts:
Deborah Rathjen, Ph.D., Executive Chair of the Board and
CEOdeborah@bioasis.us203-533-7082
Investor Contact:Graeme DickColwell Capital
Corp.graeme@colwellcapital.com403-561-8989
1 Thom G, Tian MM, Hatcher JP, et al. A peptide derived from
melanotransferrin delivers a protein-based interleukin 1 receptor
antagonist across the BBB and ameliorates neuropathic pain in a
preclinical model. J Cereb Blood Flow Metab. 2019;39(10):2074-2088.
doi:10.1177/0271678X18772998
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