Arix Bioscience PLC (ARIX) 
Holding(s) in Company 
24-Jan-2024 / 17:30 GMT/BST 
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TR-1: Standard form for notification of major holdings 
 
NOTIFICATION OF MAJOR HOLDINGS (to be sent to the relevant issuer and to the FCA in Microsoft Word format if possible) 
i 
 
1a. Identity of the issuer or the underlying issuer of existing shares to which voting    Arix Bioscience Plc 
rights are attached ii: 
1b. Please indicate if the issuer is a non-UK issuer (please mark with an "X" if appropriate) 
Non-UK issuer 
2. Reason for the notification (please mark the appropriate box or boxes with an "X") 
An acquisition or disposal of voting rights                                                                  X 
An acquisition or disposal of financial instruments 
An event changing the breakdown of voting rights 
Other (please specify) iii: 
3. Details of person subject to the notification obligation iv 
Name                                                                                      RTW Investments, LP 
City and country of registered office (if applicable)                                     New York, USA 
4. Full name of shareholder(s) (if different from 3.) v 
Name                                                                                      RTW Biotech Opportunities 
                                                                                          Operating Ltd 
City and country of registered office (if applicable)                                     St Peter Port, Guernsey 
5. Date on which the threshold was crossed or reached vi:                                 17/01/2024 
6. Date on which issuer notified (DD/MM/YYYY):                                            22/01/2024 
7. Total positions of person(s) subject to the notification obligation 
                                                                    % of voting rights      Total 
                                                                    through financial       of     Total number of 
                                       % of voting rights attached  instruments             both   voting rights held 
                                       to shares (total of 8. A)    (total of 8.B 1 + 8.B   in %   in issuer (8.A + 
                                                                    2)                      (8.A + 8.B) vii 
                                                                                            8.B) 
Resulting situation on the date on     25.52                        0.00%                   25.52% 33,023,210 
which threshold was crossed or reached 
Position of previous notification (if 
                                       n/a                          n/a                     n/a 
applicable) 
 
8. Notified details of the resulting situation on the date on which the threshold was crossed or reached viii 
A: Voting rights attached to shares 
Class/type of            Number of voting rights ix        % of voting rights 
shares 
                         Direct            Indirect        Direct                                       Indirect 
ISIN code (if possible) 
                         (DTR5.1)           (DTR5.2.1)     (DTR5.1)                                     (DTR5.2.1) 
GB00BD045071             0                 33,023,210      0.00%                                        25.52% 
 
 
SUBTOTAL 8. A            33,023,210                        25.52% 
 
 
B 1: Financial Instruments according to DTR5.3.1R (1) (a) 
                                    Exercise/          Number of voting rights that may be acquired if 
Type of financial        Expiration Conversion Period  the instrument is                                % of voting 
instrument               date x     xi                                                                  rights 
                                                       exercised/converted. 
 
 
 
                                    SUBTOTAL 8. B 1 
 
 
B 2: Financial Instruments with similar economic effect according to DTR5.3.1R (1) (b) 
                                                  Physical or 
Type of financial      Expiration   Exercise/     cash                                                  % of voting 
instrument             date x       Conversion                 Number of voting rights                  rights 
                                    Period xi     Settlement 
                                                  xii 
 
 
 
                                                  SUBTOTAL 
                                                  8.B.2 
 
 
 
9. Information in relation to the person subject to the notification obligation (please mark the 
applicable box with an "X") 
Person subject to the notification obligation is not controlled by any natural person or legal entity and 
does not control any other undertaking(s) holding directly or indirectly an interest in the (underlying) 
issuer xiii 
Full chain of controlled undertakings through which the voting rights and/or the 
financial instruments are effectively held starting with the ultimate controlling natural person or legal 
entity (please add additional rows as necessary) xiv 
                 % of voting rights if it       % of voting rights through financial       Total of both if it equals or 
Name xv          equals or is higher than the   instruments if it equals or is higher than is higher than the notifiable 
                 notifiable threshold           the notifiable threshold                   threshold 
Roderick Wong 
RTW Investments 
GP LLC 
RTW Investments, 
LP 
RTW Biotech 
Opportunities 
Ltd 
RTW Biotech 
Opportunities    25.52%                         0.00%                                      25.52% 
Operating Ltd 
 
 
10. In case of proxy voting, please identify: 
Name of the proxy holder 
The number and % of voting rights held 
The date until which the voting rights will be 
held 
 
11. Additional information xvi 
 
 
Place of completion  London, UK 
Date of completion   19/01/2024 

----------------------------------------------------------------------------------------------------------------------- Dissemination of a Regulatory Announcement, transmitted by EQS Group. The issuer is solely responsible for the content of this announcement.

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ISIN:           GB00BD045071 
Category Code:  HOL 
TIDM:           ARIX 
LEI Code:       213800OVT3AHQCXNIX43 
OAM Categories: 2.3. Major shareholding notifications 
Sequence No.:   299502 
EQS News ID:    1822379 
 
End of Announcement  EQS News Service 
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